<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation K101E
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 7
Patients 20
Isolates 20
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)TK1002TK1002 AZT, 3TCNoneM184VK101EV35T, E36A, T39E, S48T, K173T, Q174K, G196R, T200A, Q207E, R211K, V245K, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293VC
Deshpande (2009)Pat20920RTFJ530732D4T, 3TC, AZTNoneM41L, D67N, L74IV, M184V, L210W, T215Y, K219KNA98G, K101E, V108I, Y181CFGVK20R, K32T, V35K, T39D, E44D, S48T, V60I, V118I, D121Y, K122E, I135R, S162A, K173ST, V189I, T200A, E203V, Q207E, R211K, K223Q, T240K, V245QC
Van Zyl (2013)704311.ZA.EC098KC423703D4T, 3TCNoneM184MVK101E, G190AP9PS, V35T, E36A, T39E, S48T, K122E, D123S, E138A, K173T, Q174K, D177E, T200A, I202V, Q207N, R211KC
 81010.ZA.GT1465KC423253AZT, 3TCNoneM184VK101EK20KR, E28K, K32E, V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, I178L, V179I, G196E, T200A, Q207A, F214L, V245QC
 80310.ZA.WC077KC423053ABC, 3TCNoneM41L, D67N, V75M, M184V, T215YA98G, K101E, G190AE28K, K32I, V35T, T39D, S48T, V60I, K122E, D123S, K173A, Q174E, D177E, T200A, Q207E, H208Y, R211K, V245QC
 111808.ZA.EC010KC423322AZT, DDINoneM41L, D67N, K70R, V75M, L210W, T215F, K219QA98G, K101EE28K, K32I, V35T, T39E, V60I, K122E, D123DG, I135V, S162C, K173A, Q174K, D177E, I178L, G196GE, T200A, K201KR, E203A, Q207E, H208Y, R211K, L228H, V245QC
 26012.ZA.NL010KC423765AZT, 3TCNoneD67N, K70R, M184V, T215F, K219EA98G, K101E, Y181CV35T, E36A, T39E, S48T, V60I, K122E, D123S, T139R, E169A, K173A, Q174E, T200A, E203K, Q207E, F214L, V245KC
 115211.ZA.NL004KC423718AZT, 3TC, DDINoneD67N, K70R, M184V, K219QA98G, K101EK20R, V35T, T39E, S48T, V60I, K122E, D123N, I135V, E138A, S162C, K173T, Q174KR, V179I, G196E, T200A, Q207K, R211T, D237N, V245QC
Acharya (2014)DGP113DGP113KJ185283TDF, 3TCNoneM41L, D67N, T69D, M184V, L210W, T215FK101E, K103NV8I, V35T, T39D, S48T, V60I, D121Y, K122E, I135T, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292IC
 DGP091DGP091KJ185261AZT, 3TCNoneM184VK101E, G190AV35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, D177E, T200A, Q207E, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, P294QC
Steegen (2014)10ZAKS07210ZAKS072KJ176354D4T, 3TCNone K101E, E138KP4S, E6K, K11S, K20R, V35T, E36A, T39E, S48T, V90I, K122E, D123G, S162A, T165I, K173T, Q174K, D177DE, I178IM, V179A, T200A, I202IV, Q207E, R211K, F214L, V245Q, E248D, D250DE, A272P, K277KR, L283I, E291D, V292IC
Neogi (2016)95513.ZA.WC329KT593521ABC, 3TCNoneL74V, Y115F, M184VK101E, Y181CP9S, V35T, E36A, T39E, S48T, V60I, W88C, K122E, D123G, E138A, Q174E, T200A, Q207E, R211Q, F214L, H221Y, V245Q, E248DC
Posada Cespedes (2017)453315.ZA.WC601 AZT, 3TCNoneM184V, T215FA98G, K101E, G190AV8I, E28K, K32IT, V35K, T39E, S48T, V60I, I132IV, S162Y, K173A, Q174K, D177EG, V179VI, T200A, Q207E, R211K, V245QC
 575515.ZA.EC1670 AZT, 3TCNoneK65RK101E, G190SP4S, V35T, T39E, S48T, S68G, K122E, D123N, E138A, I142V, S162C, K173A, D177E, T200A, E204Q, Q207D, R211K, V245QC
 157614.ZA.GT3340KX544225TDF, 3TCNone K101EV35T, T39E, S48T, E138G, K173T, T200A, R211K, V245NC
 318315.ZA.GT4435 AZT, 3TCNone K101E, E138KK20KR, V35T, E36A, T39E, S48T, K122E, S162N, K173A, Q174K, D177E, G196M, T200A, Q207E, R211K, V245Q, E248DC
 111113.ZA.EC787KX542809TDF, 3TCNoneM184V, T215FYA98G, K101E, V108VI, G190SV35T, E36A, T39D, S48ST, V60I, K122E, D123G, I135L, E138A, Q174N, V179I, T200A, Q207D, R211K, V245QC
 431614.ZA.GT3529KX544372AZT, 3TCNone K101E, K238TE6ED, V35T, T39E, K103R, K122E, D123G, I135T, E138A, S162C, T165I, K173A, Q174K, D177E, I178L, V179T, T200A, Q207E, R211K, V245QC
 50714.ZA.WC459KX544720AZT, 3TCNoneM184VK101E, G190AV35T, E36A, T39E, S48T, K122E, T165I, K173T, D177E, I178M, T200A, Q207A, V245QC
 154212.ZA.GT2434 TDF, 3TCNone K101E, G190AK20R, V35T, T39E, S48T, V60I, A98S, K122E, D123S, I135V, E138A, K173T, Q174K, T200A, Q207E, R211K, D237E, P243T, V245Q, E248D, D250EC