<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype C
Gene RT
Mutation L100I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 16
Isolates 22
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patNIB01_NIB719AJ577965AZT, DDI, 3TC, ABCEFVK65R, L74V, M184VL100I, K101E, K103N, V106MK20R, V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177E, T200A, Q207E, R211KC
Non-B Workgroup (2005)TK3010TK3010 DDC, D4T, DDI, 3TC, ABCEFVD67N, T69D, K70R, K219QA98G, L100I, K103NT7S, V35T, E36A, T39E, S48T, V60I, K122E, D123G, A129G, I135V, N136H, T165TI, K173T, Q174K, D177E, I178L, T200A, E203K, Q207E, R211K, V245Q, A272P, T286TA, V292I, I293V, K311R, V317A, Q334H, G335DC
  TK3010a DDC, D4T, DDI, 3TC, ABC, AZTEFVD67N, T69D, K70R, V75I, K219QA98G, L100I, K103NV35T, E36A, T39D, S48T, V60I, K122E, D123G, I135V, S162C, K166KR, K173T, Q174K, D177E, I178L, T200A, E203K, Q207E, R211K, V245Q, A272P, V292I, I293V, K311R, V317A, Q334H, G335D, Q340X, Y342XC
 TK3019TK3019 D4T, DDI, AZT, 3TC, ABCNVP, EFVM41L, D67N, T69D, K70R, L74V, M184V, T215YA98G, L100I, K103ND17DE, G18GV, V35T, T39A, E44D, S48T, V60I, K122E, D123S, K173A, Q174R, G196K, T200A, Q207E, H208Y, W212M, D218E, V245Q, A272P, K277R, E291D, V292I, I293VC
  TK3019a D4T, DDI, AZT, 3TC, ABCNVP, EFVM41L, D67N, T69D, K70R, L74V, T215F, K219WA98G, L100I, K103NV35T, T39A, E44D, S48T, V60I, S117A, V118I, K122E, D123S, K173A, G196E, T200A, E203V, Q207E, H208Y, W212G, G213W, D218E, L228H, V245Q, A272P, K277R, E291D, V292I, I293VC
Marconi (2008)ICH28ICH028EU308018D4T, 3TCEFVM184V, T215FL100I, K103NK122E, I135L, E138R, K173A, D177G, T200A, E203K, Q207D, R211K, Q242R, V245RC
 SW030sw030EU308043D4T, 3TCEFVD67DN, K70KR, L74I, V75IT, M184V, K219EA98AG, L100I, K103N, P225HS48T, V60I, K122E, D123N, I135IMT, K173A, D177E, G196K, T200A, Q207E, R211K, V245QC
 SW033sw033EU308046AZT, 3TCEFVD67N, K70R, M184V, T215Y, K219EL100I, K103N, Y181YFS48T, V60I, K122E, D123S, I135L, S162D, S163T, E169A, K173A, Q174K, D177E, V179VI, G196E, T200A, E203K, Q207E, V245QC
 SW098SW098EU308106D4T, DDIEFVD67G, K70R, K219EL100I, K103NV60I, T69TN, K122E, D123G, K173A, Q174K, D177E, T200E, I202V, Q207E, R211K, F214L, V245QC
Pillay (2008)DR5DR5AY589870AZTEFVD67N, K70RL100I, K103NK20R, V35T, E36A, T39D, V60I, K122E, D123S, K173A, D177E, I178L, T200A, E203K, Q207E, R211Q, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293VC
Wallis (2009)GT00240772GT00240772 AZT, 3TCEFVD67N, K70R, M184V, T215F, K219EL100I, K103NV35T, T39E, S48T, T69N, V90I, K122E, D123G, T139K, K173A, D177E, T200A, E204Q, R211K, L228R, V245Q, A272P, K281R, E291D, I293VC
 23583052358305 D4T, 3TCEFVD67N, M184V, T215YL100I, K103NV35T, T39E, K122E, D123S, T139K, K173A, D177E, I178L, G196T, T200A, Q207E, P243T, V245Q, E248D, A272P, L279M, E291D, I293VC
 GT00327585GT00327585 D4T, 3TCEFVD67N, M184VL100I, K103N, E138KV35T, T39D, S48T, V90I, K122E, D123G, T165IV, K173A, T200A, Q207K, R211K, V245Q, D250DE, A272P, K281R, L283I, E291D, V292I, I293VC
 TJC2416769TJC2416769 D4T, 3TCEFVD67DN, M184V, T215TFISL100I, K103N, P225PHL34LI, V35T, T39E, S48T, K122E, D123N, Q174L, D177DN, T200A, Q207E, R211K, F214L, D218DE, H221HY, V245Q, E248N, D250E, A272P, E291D, V292I, I293VC
El-Khatib (2010)Pat05510ZA_SAVE2324HQ012333AZT, 3TCEFVV75I, M184MIVL100I, K101KE, V106M, G190GAK22R, I31L, V35T, T39A, E40D, S48T, K64R, W88S, V90VI, V118I, K122E, E138A, T165I, K173I, Q174K, T200A, Q207E, R211K, F214L, H221HY, V245Q, E248NC
Green (2011)707PKE06F707PKE06FHM623498D4T, 3TCEFVD67N, T69TADN, K70R, M184V, K219QL100I, K103N, P225PHV35T, T39E, S48ST, V60I, K122E, I135IT, K173T, Q174K, D177E, T200A, Q207A, H221Y, V245Q, A272P, K277KR, T286A, A288AT, E291D, V292I, I293V, D324DEC
Sigaloff (2011)GT00240772GT00240772_1JN381581AZT, 3TCEFVD67N, K70R, M184V, T215F, K219EL100I, K103NV35T, T39E, S48T, T69N, V90I, K122E, D123G, T139K, K173A, D177E, T200A, E204Q, R211K, L228R, V245Q, A272P, K281R, E291D, I293V, V317XC
  GT00240772_2JN381582AZT, 3TCEFVD67N, K70R, M184V, T215F, K219EL100I, K103NV35T, T39E, S48T, T69N, V90I, K122E, D123G, T139K, K173A, D177E, T200A, E204Q, R211K, L228R, V245Q, A272P, K281R, E291D, I293VC
 GT00327585GT00327585_1JN381602D4T, 3TCEFVD67N, M184VL100I, K103N, E138KV35T, T39D, S48T, V90I, K122E, D123G, T165IV, K173A, T200A, Q207K, R211K, V245Q, D250DE, A272P, K281R, L283I, E291D, V292I, I293VC
  GT00327585_2JN381603D4T, 3TCEFVD67N, M184VL100I, K103N, E138KV35T, T39D, S48T, V90I, K122E, D123G, T165IV, K173A, T200A, Q207K, R211K, V245Q, D250DE, A272P, K281R, L283I, E291D, V292I, I293VC
 GT00443767GT00443767JN381616D4T, 3TCEFVA62AV, K65R, Y115YF, M184VL100I, K103NK20KR, V35T, T39E, K122E, D123DN, I142K, K173T, Q197P, T200A, Q207E, L228LR, D250E, A272P, T286A, E291D, V292I, I293V, A304EC
van Zyl (2011)A72A72JN638221D4T, 3TCEFVM184VL100I, K103NI5V, V35T, T39A, S48T, V60I, V90I, K122E, D123G, I135T, S162Y, K173A, D177E, G196K, T200A, Q207E, R211K, F214L, V245QC

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