<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation N348T
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 5
Patients 23
Isolates 23
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Gomez-Carrillo (2004)9876698766AY365581NRTINNRTIM184VK103N, V108I, Y188YHK49KR, D177E, F214L, R284K, T286A, I293V, K311KR, Q334L, N348T, M357T, G359S, T369V, E396D, A400LB
 103620103620AY365684NRTINNRTIM41L, D67N, K70R, T215F, K219E K22R, A33AG, V35T, Y56YC, V60I, T69TN, W88C, V118I, K122E, I135T, R211K, F214L, L228H, V245Q, E248D, K281R, I293IV, E297R, N306ND, I341V, N348T, V365I, L368I, I375V, T386I, K390R, A400TB
 116850116850AY365934NRTINNRTID67N, K70R, L74I, Y115F, M184V, T215I, K219EY181IV35T, V60I, K122E, I135V, I178L, V179I, T200V, I202V, F214L, L228H, V245I, I293V, I341V, F346Y, N348T, M357T, T386I, A400VB
 123807123807AY366025NRTINNRTID67N, K70R, M184V, T215F, K219QK101KHNQ, K103KN, Y181C, G190GAE28A, V35M, T69N, T200E, I202V, R211A, L228H, V245M, I293V, E297K, G335GS, I341F, N348T, G359S, T369V, A371V, I375V, A376T, K390R, E399DB
Baxter (2006)12-10941094-40614DQ879100NRTINNRTIM41L, T69D, L210W, T215YK101PV111I, V118I, I142T, T200A, H208Y, R211K, L228H, A272S, A288S, S322T, I329L, N348T, M357T, A360V, E399D, A400TB
 48-30023002-30225DQ877912NRTINNRTIM41ML, D67N, K70R, L74IV, Y115YF, M184V, T215F, K219QY188LV60I, T69N, D123E, I135T, T139I, K166R, D177E, V179I, T200A, F214L, D218E, A272P, K277R, E297K, Q334L, N348T, R356K, A360V, V365VI, A376T, E399DB
 48-30213021-30313DQ877931NRTINNRTIM41L, D67N, T69D, L74V, L210W, T215Y, K219RK101E, Y181C, G190AT39A, E44D, V111I, V118I, K122E, I135T, E203K, H208Y, R211Q, K223Q, V245T, K277R, Q278E, T286A, E297R, N348T, R356K, T362S, E370D, K385KR, T386TI, K390RB
 48-30833083-30313DQ877992NRTINNRTIM41L, D67N, L74IV, M184V, L210W, T215YV108I, Y181YCK20R, V35VI, K43E, E44D, K102Q, V118I, K122E, D123E, S162Y, V179VI, V189VI, E203K, Q207E, H208HY, R211K, K223PT, A272P, K277R, T286A, I293V, E297R, G335S, N348T, R356K, G359S, A360T, K366R, A371V, K385KR, K390R, A400TB
 48-40794079-30225DQ878308NRTINNRTID67N, K70R, M184V, T215F, K219EK103N, Y181C, G190AK20R, V35I, D121H, K122E, I135T, Q174A, D177E, T200A, E203A, Q207E, L228H, V245VE, A272P, K277R, T286P, A288S, P294T, E297K, I326V, Q334L, N348T, R356K, G359S, A360T, T377N, T386I, K390R, E399D, A400TB
 48-72017201-30808DQ879026NRTINNRTI K103N, V106AE6K, I50L, K122E, S162C, T200A, E203D, R211K, I293V, I329L, N348T, G359S, T377V, K390R, E399D, A400TB
Riddler (2008)62447161337IbHM056583D4T, 3TCEFVM184VK103NK20R, T165L, I178M, R211K, F214L, V245A, A272P, A288S, I293V, A327V, G335D, N348T, M357T, A360AT, T369A, A376T, K390R, E399D, A400T, T403S, V435I, G436E, L452E, V466I, V467VI, H483Y, K512R, S519C, V548I, A554K, K558RB
Dau (2010)07157A07157AGU581823NRTINNRTIM41L, L74LV, L210W, T215YK103N, Y181CK20R, E44D, V118I, I135V, S162C, V179VI, R211K, L228R, Q242QL, V245EK, I293V, N348T, M357T, A400TB
 07215A07215AGU581824NRTINNRTIM184V, T215YK103NK20R, E138A, S162C, T200A, R211K, K277R, T286A, E297K, E312A, I326V, P345Q, N348T, A376S, T377L, T386I, A400TB
 10961A10961AGU582025NRTINNRTIM41L, D67N, K70R, M184V, T215FY, K219EK103N, Y181YCV35K, T39A, V60I, K102R, I135T, I178IM, T200TA, D218DE, L228H, T286A, E297K, K311KR, Q334QE, N348T, A360T, K366KR, S379G, T386I, K390R, A400TB
 11025A11025AGU582029NRTINNRTIM41L, D67N, V75LM, F77L, M184V, L210W, T215YK103N, Y318FV35L, T39K, E40F, K43E, V118I, K122E, I135M, E138Q, T200TAEK, Q207DE, R211K, Q278H, A288S, I293V, E297A, D324DE, N348T, M357T, T386I, K390R, A400TB
 11817A11817AGU582053NRTINNRTIL74V, Y115F, T215YK101E, Y181C, G190AV35M, K43E, S68G, A98S, D121C, K122E, T165TA, D177EG, V179I, T200A, P243S, I244IV, T286A, I293V, E297K, N348T, M357T, K366KR, A376S, K385R, A400TB
Jones (2012)139475139475JN669577NRTINNRTIM41L, D67N, L210W, T215Y, K219RK103N, V106ME44D, K102R, K122E, D123E, I135T, V179I, G196E, T286P, V292I, I293V, E297K, S322T, N348T, G359S, A371T, K388R, E399D, A400LB
 143239143239JN669639NRTINNRTID67N, K70R, M184V, T215Y, K219EK101E, V108I, Y181C, G190A, K238TI2V, K20KR, V35L, T39A, R78RG, L109I, I135R, D177E, W229W*, G231GD, E233E*, T240TA, T286A, V292VI, P294T, Q334L, N348T, M357A, T377M, K390R, A400TB
 154971154971JN669828NRTINNRTIM41L, D67N, K70R, T215F, K219EL100LI, K103N, G190GAE6EK, K22R, V35T, T39TA, V60I, W88C, V90VI, A98AS, V118I, K122E, I135T, R211K, F214L, L228H, V245Q, K275KR, I293V, E297R, I341V, N348T, V365I, L368I, I375V, V381I, T386I, K390RB
 158997158997JN669937NRTINNRTIM41L, L210W, T215Y, K219R T39A, K122E, I135T, S162C, I202IV, L228R, V245E, E248D, K277R, I293V, I329IL, N348T, A360T, K390RB
 166819166819JN670135NRTINNRTIK70G, M184V A98S, D121H, K122E, I135T, Q174K, Q197E, F214L, N255K, T286P, A288S, I293V, E297A, S322T, D324E, I329L, N348T, T386I, K390R, I393NS, Q394E, A400TB
 176311176311JN670392NRTINNRTIM41ML, D67N, K70R, T215F, K219KEY181CK32Q, K122E, I135R, I142V, K166R, T200A, I202V, R211K, H221Y, A272P, I293V, Q334L, N348T, A376T, V381I, T386I, A400TB
 199213199213JN671154NRTINNRTIM41L, D67N, T69D, K70R, M184V, L210LW, T215F, K219Q V35L, T39E, V118VI, K122E, I135T, K173KQ, V179I, D218E, L228H, A272P, T286P, I293V, K311R, N348T, R356RK, A360AT, E370D, A376T, T386V, K390R, E399EGB