Reverse Transcriptase Inhibitors

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Reverse Transcriptase Inhibitors

Subtype	B
Gene	RT
Mutation	P225H
Rx	>= 1 NNRTI (+/- NRTI)
IncludeMixtures	No

References	27
Patients	174
Isolates	206

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	NRTIs	NNRTIs	NRTIDRMs	NNRTIDRMs	OtherMut	Subtype
Deeks (1999)	SD-21	SD-21	AF124556	D4T	EFV		K103N, P225H	K122E, D123E, I135M, S162C, T200A, Q207A, R211K, V245Q, K277R, I293V	B
Bacheler (2000)	LB3-P22	P22-70		NRTI	EFV		K103N, P225H	K122E, D123E, I135V	B
	LB3-P24	P24-94		NRTI	EFV		K101P, K103N, P225H	K122E, E169D, T200E, Q207E	B
	LB3-P28	P28-44		NRTI	EFV		K103N, P225H	K122E, D123E, I135L, S162C, D177E, T200A, Q207E	B
		P28-48		NRTI	EFV		K103N, P225H	K122E, D123E, I135L, S162C, D177E, T200A, Q207E	B
		P28-58		NRTI	EFV		K103N, P225H	K122E, D123E, S162C, D177E, T200A, Q207E	B
	LB3-P47	P47-62		NRTI	EFV	K70R	K103N, P225H	K122E, D123N, I142V, T200A	B
		P47-71		NRTI	EFV	K70R	K103N, P225H	K122E, D123N, I142V, T200A	B
	LB3-P55	P55-72		NRTI	EFV		K103N, P225H	K122E, I135T, K173Q, D177E	B
		P55-96		NRTI	EFV		K103N, P225H	K122E, I135T, K173Q, D177E	B
		P55-108		NRTI	EFV		K103N, P225H	K122E, I135T, K173Q, D177E, G196R	B
	LB3-P57	P57-24		NRTI	EFV		K103N, P225H	Q207H, R211K	B
	LB3-P69	P69-24		NRTI	EFV	K70R	K103N, P225H	I178M, G196E, R211K	B
		P69-32		NRTI	EFV	K70R	K103N, P225H	I178M, G196E, R211K	B
		P69-39		NRTI	EFV	D67N, K70R	K103N, P225H	I178M, G196E, R211K	B
		P69-44		NRTI	EFV	K70R	K103N, P225H	I178M, G196E, R211K	B
	LB3-P70	P70-44		NRTI	EFV		K103N, P225H	V21I, K122S, I135L, S162C, E169D, D177E, G196E	B
	LB3-P71	P71-86		NRTI	EFV		K103N, P225H	I135T, R211K	B
	LB3-P80	P80-100		NRTI	EFV		K103N, P225H	V35I, D121H, K122E, I135T, E169D, D177E, F214L	B
	LB3-P81	P81-44		NRTI	EFV		K103N, P225H	I135V, S162C	B
		P81-72		NRTI	EFV		K103N, P225H	V60I, I135V, S162C	B
	LB3-P87	P87-60		NRTI	EFV		K103N, P225H	K122E, D123E, I135M, S162C, T200A, Q207A, R211K	B
		P87-72		NRTI	EFV		K103N, P225H	K122E, D123E, I135M, S162C, T200A, Q207A, R211K	B
	LB3-P89	P89-32		NRTI	EFV		K103N, P225H	K101Q, K122P, S162C	B
		P89-44		NRTI	EFV		K103N, P225H	K101Q, K122P, D123E, S162C	B
	LB3-P91	P91-85		NRTI	EFV	T215I	K103N, P225H	T39A, S48T, K122E, S162C	B
	LB3-P93	P93-36		NRTI	EFV	D67N, T69D, K70R, K219Q	K103N, P225H	V35T, V60I, D123E, I135T, D177E, I178V, G196E, E204K, Q207E	B
		P93-40		NRTI	EFV	D67N, T69D, K70R, K219Q	K103N, P225H	V35T, V60I, D123E, I135T, D177E, I178V, G196E, E204K, Q207E	B
		P93-51		NRTI	EFV	D67N, T69D, K70R, K219Q	A98G, K103N, P225H	V35T, V60I, D123E, I135T, D177E, I178V, G196E, E204K, Q207E	B
		P93-63		NRTI	EFV	D67N, T69D, K70R, K219Q	K103N, P225H	V35T, V60I, V90I, D123E, I135T, D177E, I178V, G196E, E204K, Q207E	B
	LB3-P98	P98-33		NRTI	EFV	K70R	K103N, P225H	D123E, E138A, I178M, V179I	B
		P98-41		NRTI	EFV	K70R	K103N, P225H	D123E, E138A, I178M, V179I	B
		P98-45		NRTI	EFV	K70R	K103N, P225H	D123E, E138A, I178M, V179I	B
	LB4-P100	P100-56		AZT, 3TC	EFV	D67N, K70R, T215I, K219E	K103N, P225H	K20R, I135T, T200A, R211K	B
	LB4-P101	P101-72		AZT, 3TC	EFV		K103N, P225H	R83K, I135L, Q174H, Q207K, R211S	B
	LB4-P105	P105-12		AZT, 3TC	EFV	M41L, D67G, K70R, M184V, K219Q	K103N, P225H	K20R, V60I, T69N, K101Q, K104N, I135T, I202V, R211G	B
	LB4-P114	P114-24		AZT, 3TC	EFV	M184V	K103N, P225H	D86E, I135V, S162C	B
		P114-37		AZT, 3TC	EFV	M184V	K103N, P225H	D86E, I135V, S162C	B
		P114-59		AZT, 3TC	EFV	M184V	K103N, P225H	K20R, D86E, I135V, S162C	B
	LB4-P116	P116-25		AZT, 3TC	EFV	K65R, M184V	K103N, P225H	K11R, K64R, I135V, T165V, H198Y, F214L	B
	LB4-P122	P122-31		AZT, 3TC	EFV	K70R, M184V	K103N, P225H	K20R, F214L	B
	LB4-P126	P126-34		AZT, 3TC	EFV	D67N, K70R, M184V, K219Q	K103N, P225H	V35M, D123E, F214L	B
		P126-59		AZT, 3TC	EFV	D67N, K70R, K219Q	K101E, P225H	V35M, K103R, D123E, F214L	B
	LB5-P164	P164-36		AZT, 3TC	EFV	M184V	K103N, P225H	I31T, V35I, D123E, D177E	B
	LB5-P170	P170-60		AZT, 3TC	EFV		K103N, P225H	K11R, I135L, I178M, T200E, R211K	B
Parkin (2000)	SD-21	SD-21_12	AF294546	D4T, ABC, 3TC	EFV	D67DG, M184MI	K103N, P225H	K122E, D123E, I135IM, S162CY, T200A, Q207A, R211K, L228LQ, V245Q, K277R, I293V	B
		SD-21_16	AF294547	D4T, ABC, 3TC	EFV		K103N, P225H	K122E, D123E, S162C, T200A, Q207A, V245Q, K277R, I293V	B
		SD-21_20	AF294548	D4T, ABC, 3TC	EFV	D67DG, M184I	K103N, P225H	K122E, D123E, S162C, T200A, Q207A, R211K, L228LQ, V245Q, K277R, I293V	B
		SD-21_24	AF294549	D4T, ABC, 3TC	EFV	D67DG, M184IV	K103N, P225H	K122E, D123E, S162C, T200A, Q207A, R211K, L228LQ, V245Q, K277R, I293V	B
Bacheler (2001)	DMP003-28	03-28321A	AF349336	NRTI	EFV		K103N, P225H	K122E, D123E, I135L, S162C, D177E, T200A, Q207E, A272P, K277R, Q278N, T286A, I293V, D324E, G333E, M357MT, R358K, G359S, K390R	B
	DMP003-47	03-47497	AF349345	NRTI, D4T	EFV	K70R	K103N, P225H	K122E, D123N, I142V, T200A, R211RT, V245E, I293V, N348NT, M357T, A376ST, K390R, A400S	B
	DMP003-55	03-55504	AF349350	NRTI	EFV		K103N, P225H	K122E, I135T, K173Q, D177E, V245M, A272P, Q334C, T338S, M357A, I375V, T386TA, K390R	B
	DMP003-70	03-70290A	AF349358	NRTI, D4T	EFV		K103N, P225H	V21I, K122S, I135L, S162C, E169D, D177E, G196E	B
Gonzales (2001)	CA4349	CA10547	AY031212	DDI, D4T, AZT, 3TC, ABC	EFV	D67T, K70R, M184V, T215V, K219E	K103N, P225H	K20R, I31IR, T69N, I135M, A158AT, R211K, A272P, K281R, R284K, T286AG, E297K	B
	CA4871	CA11968	AY031511	AZT, 3TC, D4T	NVP, EFV		K103N, P225H	R72RG, A98S, K122E, A158S, G196E, D237N, V245E, T286A, E297K	B
	CA6605	CA16459	AY032510	AZT, 3TC, DDI	EFV	L74V	L100I, K103N, P225H	K49R, I50V, R83K, K122KE, I135IL, T200I, K275R, I293V, A299AG	B
	CA6790	CA16832	AY032523	AZT, 3TC	NVP, EFV	M184V	K103N, P225H	K20KR, I135T, V245K, K277R, I293V, E297A, E302ED	B
Margot (2002)	MM-224836495	2248364951		NRTI	NNRTI	M41L, L74V, M184V, T215Y	K103N, P225H, M230L	V21I, V35M, T39A, K223KR, W229L, V245E, I293V, E297K, D324E, A360V, K366R, K390R	B
Gonzales (2003)	CA1535	CA13105	AF514096	AZT, DDI, 3TC, D4T, DDC, ABC	DLV, EFV	L74V, M184V, K219E	K103N, V108I, Y181C, P225H	S68G, K101Q, I135T, S162A, R211K, L228H, V245E, A272P, V276I, K277R, K281KR, L283I, E297A, A299AG	B
	CA2091	CA13869	AF514137	AZT, 3TC, D4T, DDC	EFV	M41L	K103N, P225H	K122E, D123N, T200A, R211RK, A272S, T286TA, E297Q	B
Shafer (2003)	A384_1209	1209b	EF548279	D4T, DDI, 3TC	EFV	M184V	K103N, P225H	I135V, D177G, I178M, R211K, V245K, T253S, A272P	B
		1209c	EF548280	D4T, DDI, 3TC, AZT	EFV	A62AV, M184V	K103N, P225H	I135V, D177G, I178M, R211K, V245K	B
	A384_1933	1933c	EF548665	D4T, DDI, AZT, 3TC	EFV	M184V	K103N, P225H	D123E, I135T, S162C, D177E, Q207E, R211K	B
	A384_6199	6199c		D4T, DDI, AZT, 3TC	EFV	M184V	K103N, P225H	V35A, T39A, V60I, R83K, D123E, D177E, V245E, A272P, T286A, E297K	B
		6199d	EF548676	D4T, DDI, AZT, 3TC	EFV	M184V	K103N, P225H	V35A, T39A, V60I, R83K, D123E, D177E, V245E	B
	A384_3341	3341b	EF548975	D4T, DDI	EFV		K103N, P225H	K20R, G196E, T200I, R211K, K259X	B
		3341c	EF548976	D4T, DDI, AZT, 3TC	EFV	M184V	K103N, P225H	G196E, T200I, R211K	B
	A384_3918	3918c	EF549181	AZT, 3TC, D4T, DDI	EFV		K103N, V106A, P225H	I37X, K122E, I135V, I142V, D177E, G196R, T200A, R211K	B
Gulick (2004)	RG377	RG377w44		ABC, AZT, 3TC, D4T	EFV	M184V	K103N, P225H	V60I, V90I, A98S, K102KR, D123E, I135V, I142V, R211K	B
	RG455	RG455w156		AZT, 3TC	EFV	M184V	K103N, P225H	K43E, A98S, K101Q, K122P, I142V, S162SN, Q174K, D177E, I178L, T200E, R211T, V245E	B
	RG460	RG460w104		AZT, 3TC	EFV	A62AV, M184V	K103N, P225H	D123E, I135ILPT, E169D, Q174QK, G196E	B
	RG58	RG58w122		AZT, 3TC	EFV	M184V	K103N, P225H	S48T, I135V, S162C, V245E	B
	RG60	RG60w96		ABC, AZT, 3TC	NVP		K103N, P225H	V60I, D121H, K122E, I135T, D177E, R211K	B
Montes (2004)	MB_patCAR	02_CAR707	AJ577858	AZT, 3TC, D4T	EFV, NVP	M41L, M184V	K103N, P225H	T200A, R211T	B
Garcia-Bujalance (2005)	GBS_24	GBS_24	AY872359	AZT, 3TC, D4T, TDF	EFV	K65R, M184V, K219R	K103N, P225H	K122E, I135L, G196E	B
	GBS_41	GBS_41	AY872376	AZT, DDI, DDC, 3TC, D4T	EFV	M184MV	K103N, P225H	K49R, I50V, V60VI, I135M, S162C, R211K	B
Ochoa de Echaguen (2005)	B-0258	B-0258	AY833579	D4T, 3TC	EFV	A62V, M184V	K103N, P225H, K238KT	K122E, K166KR, E194EK, G196EK, L210F, R211K, A272P, K277R, I293V	B
Rhee (2005)	CA1329	CA39039	AY802684	D4T, 3TC, AZT, Unknown	EFV, Unknown	M184V	K103N, P225H	V35R, T39A, K102Q, D123E, I135T, I142V, S162C, T200A, V245T, A272P, I293V, E297K	B
	CA2190	CA21055	AY801136	AZT, 3TC, D4T	EFV	K70R, K219Q	K103N, P225H	K102R, V118I, F214L, L228R, P243H, V245EK	B
	CA4341	CA23964	AY801306	AZT, 3TC, D4T, DDI	EFV	M41L, D67N, K70R, T215F, K219Q	A98AG, K103N, P225H	V60I, V90I, K104N, I142V, S162Y, V179X, E203D, R211K, A272P, E297K	B
	SWC-6100	6100-4969		DDC, NRTI, D4T, 3TC, DDI, ABC, Unknown	NVP, Unknown, EFV	T69D, F116Y, Q151M, M184V	V106VA, V179D, P225H	V118I, K122E, I178L, I202V, R211K, F214L	B
	SWC-3386	3386-2188		D4T, 3TC, Unknown, ABC	NVP, Unknown, EFV	L74V	A98G, V179D, Y181C, G190A, P225H	A158S, T165I, T200V	B
	CA4805	CA19928	AY801416	D4T, 3TC, ABC	EFV	M41L, L74I, M184V, T215Y	K103N, V108VI, P225H	K122E, I135M, S162Y, T200A, A272P, I293V, E297AT, S322T, Q334E, E370D, K390R, E399D, A400T, V435A, A446S, L452V, D460N, R461K, Q480H, L491S, S519N, Q524E	B
	CA5373	CA34388	AY801562	AZT, 3TC, D4T, DDI	EFV	M184MV	K103N, P225H	E6EG, K102KR, D123E, D177E, I293V	B
		CA37741	AY801563	AZT, 3TC, D4T, DDI, TDF	EFV		K103N, P225H	T39TA, D123E, D177E, I293V	B
	CA7987	CA20077	AY801883	AZT, 3TC, D4T, DDI, ABC	EFV	D67DE, L74V, M184V, K219KN	L100I, K103N, P225H	V118I, K166R, T200TA, Q207E, R211K, F214L, V245M, Q278N, I293V	B
	CA8035	CA20164	AY801920	AZT, 3TC	EFV	M184V	K103N, P225H	I135L, E203D, R211K, I257IR, K277R	B
	CA9668	CA23619	AY802049	AZT, 3TC, DDC, ABC	EFV	M184V	K103N, P225H	V35I, R83K, I178L, T200I, R211G, A272P	B
		CA23621	AY802050	AZT, 3TC, DDC, ABC, D4T	EFV	M184V	K103N, P225H	V35I, R83K, I178L, T200I, R211G, V241VM, A272P	B
	CA14363	CA34608	AY802317	AZT, 3TC	EFV	M184V	K103N, P225H, M230L	V35VI, P119PA, E138EG, S162C, I178M, T200A, V245E, A272P, K277R, K281R	B
Baxter (2006)	12-2184	2184-30807	DQ880085	NRTI	NNRTI	M184V	K103N, P225H	I135IT, S162A, V179VI, I244V	B
	12-1278	1278-30417	DQ879375	NRTI	NNRTI	L74V, M184V	K101E, G190A, P225H	D123E, S162C, D177E, I178M, V179VI, T200A, Q207E, R211K	B
	12-1255	1255-30409	DQ879354	NRTI	NNRTI	A62V, V75I, F116Y, Q151M	K103N, P225H	S68N, A98S, D123E, D177E, T200A, R211K, F214M	B
	12-1057	1057-30325	DQ879187	NRTI	NNRTI	D67N, K70R, T215F, K219Q	K103N, V108I, P225H	K101Q, K122E, D123E, I135T, D177E, I178M, H208HY	B
	12-2105	2105-30624	DQ880023	NRTI	NNRTI	D67N, K70R, M184V, T215F, K219E	L100I, K103N, P225H	V60I, V90I, K122E, I135L, S162A	B
	12-2167	2167-30702	DQ880071	NRTI	NNRTI	D67G, T69S_XG, L74I, M184MV, T215Y	K103N, V108I, P225H	R83K, K102Q, D123E, I135T, S162Y, I178ILM, T200A	B
	12-1387	1387-30521	DQ879457	NRTI	NNRTI	M41L, D67N, K70R, M184V, T215V, K219Q	K103N, V179E, P225H	V118I, L120*, K122E, D123DN, E138Q, T200A, Q207E, R211K, F214L, L228H	B
	12-1126	1126-30417	DQ879239	NRTI	NNRTI	L74I, M184V, T215V, K219Q	K103N, V108I, P225H	S48T, K122E, I135M, S162C, T200A, L228V, V245Q	B
	12-1717	1717-30424	DQ879708	NRTI	NNRTI	M41L, D67G, T69TADN, L74V, L210W, T215Y, K219R	L100I, K103N, P225H, K238T	K43Q, E44D, V118VI, K122E, I135T, E138Q, S162C, R172RK, T200TA, I202V, Q207QE, R211K	B
	12-1286	1286-30404	DQ879383	NRTI	NNRTI	T69D, K70R	K103N, P225H	W88C, I142V, I178M, F214L, L228R, V245E	B
	12-1638	1638-30311	DQ879642	NRTI	NNRTI	L74I, M184V, L210W	K103N, P225H	K102Q, K122E, S162C, G196E, T200A, Q207E, R211K	B
	12-1238	1238-30512	DQ879337	NRTI	NNRTI	D67N, K70R, M184V, K219Q	K103N, P225H	V118VI, D123E, D177EG, I178IL, R211K, F214L, V245K	B
	12-1610	1610-30616	DQ879614	NRTI	NNRTI	M41L, T215Y	P225H	K122E, I142V, K173T, V245K	B
	48-1023	1023-30623	DQ880475	NRTI	NNRTI	M41L, D67N, T69DE, L74I, M184V, L210W, T215Y, K219R	K103KN, P225H	E44D, D123E, R211K, D218E	B
	48-1043	1043-30617	DQ880492	NRTI	NNRTI	M41L, M184V, T215Y	K103N, P225H	D177E, L228V, D237E	B
	48-1047	1047-30623	DQ880496	NRTI	NNRTI	M41L, D67H, K70R, T215F, K219Q	P225H	E44EA, V60I, W88S, V90I, D123E, I135T, S162Y, D177E, L187LS, T200A, E203D, R211KT	B
	48-1115	1115-30716	DQ880556	NRTI	NNRTI	M41L, L74I, M184V, L210W, T215Y	K103N, P225H	K122E, V189I, R211RK, L228LI, V245M	B
	48-1054	1054-30701	DQ880502	NRTI	NNRTI	A62V, V75IL, F77FL, Y115F, F116Y, Q151M, M184V	K103KN, G190A, P225H	K49R, E53D, K102Q, K104R, K122E, D123E, E169D, P170PL, D177E, I202V	B
	48-3011	3011-30303	DQ877921	NRTI	NNRTI	D67N, K70R, L74V, Y115F, M184V, K219Q	K103N, P225H	K20R, K101Q, K122E, R211K, L228H, T286A, R356K, M357T, E370D	B
	48-3079	3079-30520	DQ877988	NRTI	NNRTI	M41ML, V75VL, L210LW, T215Y, N348I	L100LI, K103N, V108VI, P225H	T39TA, K102Q, K122KE, D177E, R211K, L228HR, V245MT, I293V, E297L, D324E, Q334E, I341F, M357T, S379G, K390R	B
	48-3094	3094-30331	DQ878001	NRTI	NNRTI	L74V, Y115F, M184V	L100I, K103N, P225H	V35L, K102Q, K122E, T200A, H221Y, V245E, T286A, K311KR, D324E, I329L, Y354YH, S379C, K390R	B
	48-3220	3220-30519	DQ878127	NRTI	NNRTI	M41L, T215Y	K103N, P225H	T39A, I135L, E138A, I142V, Q174R, T200A, R211K, T286A, E297K, K311R, R356K, K390R, I393M, A400AT	B
	48-4033	4033-30513	DQ878267	NRTI	NNRTI	M184V, T215Y	K103N, P225H	E6D, S68G, A98S, K101Q, I142V, D177E, V189I, T200A, R211RK, D250E, A272P, K277R, E297A, L301LM, Q334E, P345Q, A355AT, M357T, K366R, T386TI	B
	48-4118	4118-30407	DQ878349	NRTI	NNRTI	A62V, K70N, V75I, F77L, Y115F, F116Y, Q151M, M184V	K103N, V108I, P225H	K43E, T58N, K122KE, D123DE, I135T, S163A, I178M, T200A, R211K, F214M, L228H, I326V, Q334L, V365I, T386IV, K390R, E399G, A400S	B
	48-6307	6307-30924	DQ878846	NRTI	NNRTI	M184V, N348I	K103N, P225H	S48T, E53D, K122E, D123EG, I135T, I142V, S162F, R211K, A272P, K281R, T286A, I293V, E297K, P313S	B
	48-9177	9177-30911	DQ880786	NRTI	NNRTI	A62V, T215F	K103N, Y181C, P225H	K43KQ, V90VI, K122E, I135T, L228R, V245M	B
	48-9183	9183-30901	DQ880792	NRTI	NNRTI		K103N, P225H	D123E, D177E, V245R	B
	48-9283	9283-30929	DQ880874	NRTI	NNRTI	M184V	P225H	K122E, V245T	B
	48-8082	8082-30929	DQ879090	NRTI	NNRTI		K103N, P225H	I135V, S162C, F171Y, T200A, R211K, K277R, A288S, V292I, I293V, I326V, P345Q, F346Y, R356K, R358K	B
Margot (2006)	9429	9429W96		D4T, 3TC	EFV		K103N, P225H	D123E, I135T, T200I, V245I, E248D, A272S, A288S, I293V, E297A, Q334L, F346Y, R358K, K366R, T386TI, K390R	B
		9429W144		D4T, 3TC	EFV		K103N, P225H	K101KQ, K102KR, D123E, I135T, T200I, V245I, E248D, A272S, A288S, I293V, E297A, Q334L, F346FY, R358K, K366R, T386I, K390R	B
Rios (2007)	CH63	MR_CH63	EF193957	Unknown, AZT, 3TC	Unknown, EFV	M184V	K103N, P225H	E6D, K20R, E28K, K32E, V35I, A98S, I135T, D177E, T200A, Q207E, V245Q, K277R	B
	CH73	MR_CH73	EF193968	Unknown, AZT, 3TC	Unknown, EFV		K103N, P225H	V35L, I37F, K82R, I94X, I135R, S162C, G196V, T200S, R211K	B
		MR_CH73.1	EF193969	Unknown, AZT, 3TC	Unknown, EFV		K103N, P225H	V35L, K82R, K101Q, I135KR, S162C, G196V, T200S, R211K	B
Riddler (2008)	RG67743	RG67743w28		TDF, 3TC	EFV	M184V	K103N, P225H	T39A, R83K, K122E, G196E, T200A, R211A, V245E, A272P, G333E, K366R, T369A, A376T, K390R	B
Rosen-Zvi (2008)	6	00p6-1		DDC, 3TC, D4T, ABC, DDI	NVP, EFV	V75A, F77L, Q151M, K219E	K103N, Y181C, G190A, P225H	V35L, T69N, K73M, K101R, K122E, I135IV, K173T, T200E, E203K, R211K, V245E, K277R, I293V, E297Q	B
	67	00p67-1		DDC, 3TC, AZT, D4T, DDI	EFV	D67N, K70R, M184LV, K219Q	K103N, P225H, K238KN	K20R, V60I, K101KQ, I135T, S162Y, Q174QH, F214L, L228H, K277R, Q278H, T286A, D320DY	B
Cardoso (2009)	3014	BRGO3014	FJ638422	NRTI	NNRTI	M184V	K103N, P225H	S48T, K122E, D123N	B
	3060	BRGO3060	FJ638431	NRTI	NNRTI	K70R, M184V	K103N, P225H	T39A, K43Q, T69N, A98S, K122E, D123S, I142V, S162Y, V179I, T200A, R211K	B
	3090	BRGO3090	FJ638440	NRTI	NNRTI	M184V	K103N, P225H	K20R, D123E, I135T, S162C, D177E, R211K	B
	3097	BRGO3097	FJ638444	NRTI	NNRTI	M184V	K103N, P225H	R83K, I135L, S162C, G196E, R211G	B
	3139	BRGO3139	FJ638463	NRTI	NNRTI	M184V	K103N, P225H	K20R, K32R, A158S, S163ST, K173T, Q207E, R211K	B
Luo (2009)	sz.723	04HBsz.723	FJ375030	NRTI	NNRTI		K103N, P225H	I135V, S162C, T200A, R211K, L234P, A272P, K277R, Q278E, I293V, E297K, Q334L	B
	xf.776	05HBxf.776	FJ375039	NRTI	NNRTI		K101E, K103N, P225H	T58A, L92S, I135V, S162C, D177E, T200A, R206G, R211K, V245E, Q278E, I293V, T296S, P313S, Q334L	B
	sz.825	05HBsz.825	FJ375050	NRTI	NNRTI	K65R	K103N, P225H	K101R, I135V, S162C, T200A, R211K, V245E, Q278E, I293V, Q334L	B
Rhee (2009)	CA8428	CA21183	FJ983294	DDI, D4T, 3TC	EFV, NVP		K103N, P225H	K20R, V35VL, K122E, Q207E, V245E, A272P, K281R, L283LI, E297A	B
	CA14651	CA35066	FJ983392	AZT, 3TC	EFV	M184V	K103N, V108VI, P225H	K20R, K102Q, K122E, I135T, S162SC, A272S, K277R, T286A, I293V	B
	CA16310	CA38773	FJ983410	AZT, D4T, 3TC, DDI	EFV	M184V	K103N, P225H	E6D, V35T, I135IT, S162A, V179VI, I244V, K277R, Q278H, T286A, P294T	B
	CA17636	CA41513	FJ983444	AZT, 3TC	EFV	D67DN, K70KR, M184V	K103N, P225H	K20KR, D123E, I135T, R211K, F214L, A272P	B
	CA21042	CA48398	FJ983477	D4T, 3TC	NVP	L74I, M184V	K103N, P225H	K11R, I31L, K104R, K122E, I142V, R211K, L228R, T240A, V245E, D250E, A272P, K277R, L283I, P294S, T296S, E297K, K311R, D320E, G333E, Q334H, R356K, M357I	B
	CA23900	CA55428	FJ983519	TDF, 3TC	EFV	K65KR, M184V	K103N, P225H	K49R, I50V, A98S, K122E, D123DN, I135V, I142V, E169D, T200R, F214L, A272P, V276I, K277R, Q278N, L283I	B
Dau (2010)	05604A	05604A	GU581677	NRTI	NNRTI		K103N, P225H	K20R, V35I, E40D, E138Q, T200A, F214L, P243S, V245E, D250E, T286TA, V317A, M357T, A376T, T377I, Q394L, E399D	B
	06457B	06457B	GU581745	NRTI	NNRTI		K103N, P225H	V35I, T69TA, R83K, A98S, K101Q, D177E, I178IL, T200I, I202IV, R211K, V245E, A272P, T286A, I293IV, K311R, Q334K, G335D, M357T, G359S, S379G, V381I, K385R, T386I, K390R	B
	06927A	06927A	GU581799	NRTI	NNRTI	L74V, Y115F, M184V	L100I, K103N, P225H	V8VI, M16MT, T39TI, K49R, V60I, R83RK, K122E, E169D, T200A, I202V, F214L, L228R, V245E, A272P, T286A, M357V, V372I, A376C	B
	07235A	07235A	GU581826	NRTI	NNRTI	M41L, M184V, T215Y	K103N, P225H	E29D, A98S, K122E, I135V, I142V, D177E, I178M, A272P, K281R, I293V, E312EK, G333E, Q334H, M357T, T377I	B
	07530A	07530A	GU581854	NRTI	NNRTI	M184V	K103N, P225H	I135L, I142T, E169D, T200TA, R211K, S251I, T286A, I293V, Q343Q*, T362TP, K388KR	B
	07945A	07945A	GU581882	NRTI	NNRTI	D67N, T69D, K70R, M184V, T215F, K219Q	V106A, V179D, G190GA, P225H	V35T, V60I, K103R, I135T, I178M, T200A, F214L, V245E, A272P, K277R, R284RK, T286A, E297EQ, G359GS, A371AV, K390R	B
	09813A	09813A	GU581985	NRTI	NNRTI	M41L, T215Y	K103N, P225H	I135M, K173KE, Q207A, R211K, V245M, A272P, I293V, P294S, E297K, K311KQR, I329L, G333D, Q334H, A360T, V365I, E399G	B
	12960A	12960A	GU582068	NRTI	NNRTI	D67N, K70R, M184V, K219Q, N348I	K103N, P225H	V60I, V90I, K122E, D123E, I135T, I142V, S162Y, T200I, L228LH, I293V, E370A, K390R, K395KR	B
Hamkar (2010)	13	Ir-HIV-DR-13	GU724816	NRTI	NNRTI	M184V, T215Y, K219R	P225H	K49R, R83K, D86T, P95T, D123E, I135L, R143K, I159L, K166R, R172K, K173N, Q174K, D177E, T200S, E204D, K277R, Q278E, I293V, E297K, Q330R, K331T	B
	18	Ir-HIV-DR-18	GU724821	NRTI	NNRTI		P225H, K238T	V35L, E36D, R83K, L100X, K102Q, K103R, K122P, D177E, T200A, P294S, E297K	B
	20	Ir-HIV-DR-20	GU724823	NRTI	NNRTI	K70R	P225H, K238T	K64R, L100X, K122P, D177E, T286A, I293V, T296S, E297K, K311R	B
	23	Ir-HIV-DR-23	GU724826	NRTI	NNRTI	M41L, V75M, L210W, T215Y	Y181C, G190A, P225H, K238T	S68G, T69A, L100X, K101Q, K122E, I135T, I142V, T286A, I293V, T296S, E297K, K311R, D320L	B
Zolfo (2010)	A13883	A 13883 RS	HM565596	D4T, 3TC	NVP	M184V	K103N, P225H	S68G, T69TI, K102Q, D123E, K166R, I178L, G196E, T200A, Q207H, R211K, V245M	B
		A 13883 M24	HM565517	D4T, 3TC	NVP	M184V	K103N, P225H	S68G, T69I, K102Q, D123E, K166R, I178L, G196E, T200A, Q207H, R211K, V245M	B
van Zyl (2011)	A265	A265	JN638157	AZT, 3TC	EFV	D67N, T69D, K70R, M184V, T215F, K219Q	A98G, K103N, P225H	K20R, K43KR, K122E, D123N, I135T, T139V, K173E, I178M, R211K, F214L	B
Jones (2012)	129879	129879	JN669473	NRTI	NNRTI	M184V	K103N, P225H	V35T, I135V, V245M, A272P, K281R, E297K, Q334L, A376T, T386S, K390R, Q394L, E399D	B
	132656	132656	JN669514	NRTI	NNRTI	F116Y, Q151M, M184V, K219R	K103N, V108I, P225H	K20R, V35M, T39TA, K102Q, K104R, S105A, I135T, I178M, T200A, Q207E, R211K, F214L, L228R, A288S, I293V, E297A, L301M, Q334L, G335S, R356RK, T369A, T386I, K390R, T397A	B
	148307	148307	JN669709	NRTI	NNRTI	D67DN, K70KR, T215Y, K219KE	K103N, Y181C, P225H	V21VI, V60I, K102KR, K122P, I135T, S162SN, D177E, Q207E, L228R, K277R, T286A, A288T, E297A, I326V, Q334L, M357T, A360T, K390R	B
	152725	152725	JN669784	NRTI	NNRTI	L74V, M184V	L100I, K103N, P225H	V21VFL, W24W*, P25PR, V35LM, I178M, R211Q, A272P, K281R, T286A, I293V, E297K, E300ED, L310LI, K311KR, Q334QHKN, G335CS, R356K, M357T, K366R, Q367QR, A371V, A376T, I380IV, T386A, K390R	B
	154570	154570	JN669821	NRTI	NNRTI	M184V	K103N, P225H	I135L, I142V, T200TA, L210LF, R211K, Q278QH, T286A, A288AS, E297K, E300ED, I326V, V365I, A376T, S379C, V381I	B
	155141	155141	JN669832	NRTI	NNRTI	F116Y, Q151M	K103N, V108I, P225H	S68SG, T69N, D123E, S162C, K166KM, R172K, I178L, V189VI, Q197H, Q207E, R211K, D218DG, V245E, K277R, I293V, E297K, Q334L, R356K, A360T, I375V, T377K, S379C, I382V, K388R, K390R	B
	155277	155277	JN669838	NRTI	NNRTI	M41L, D67N, M184V, T215Y, K219E	K103N, P225H, K238KNT	V35E, E36D, T39A, S68G, K122E, I135T, T139K, I142T, D177E, I202V, V245M, R284RK, A288S, I293V, E297EAKT, M357T, A376T, T397TAIV	B
	156156	156156	JN669852	NRTI	NNRTI	M184V, T215F	K103S, G190A, P225H	K20R, V35K, V60I, I135V, I142V, K173N, I202V, Q207E, R211K, A272P, K277R, I293V, E297K, Q334L, M357T, A360T, E399D	B
	157481	157481	JN669887	NRTI	NNRTI	M184I, T215Y, K219R	K103N, P225H	P1PS, E6A, I31L, E44D, V90I, V118I, K122E, D123E, I178M, G196E, Q197E, T200S, E203D, Q207E, L210S, R211K, F214L, F227FV, L228R, K238I, A272P, E297K, K311KR, G333E, R358K, K366R, A371AV, A376S, S379SC, K390R	B
	159510	159510	JN669955	NRTI	NNRTI	L74I	A98G, K103N, P225H	V35T, K46Q, V60I, K122E, I135L, E138G, K173KR, A272P, T286A, P294S, E297K, S322SA, I329L, V365I, T386I, K388KR, K390R	B
	163803	163803	JN670071	NRTI	NNRTI	M41L, D67N, K70R, L74I, M184V, L210W, T215F, K219E	K103N, V108I, P225H	V60I, T69TN, K101KQ, V118VI, K122KE, D123EK, I142IT, D177E, I178M, R211K, L228H, A272P, K277KR, K281R, T290S, E297R, I329L, G333GE, R356K, G359GS, V365I, T369V, A376S, S379SC, K390R, K395R, E399D	B
	165203	165203	JN670094	NRTI	NNRTI	M41L, L210W, T215Y, K219R	K103N, P225H	I31L, A33G, V35M, E44D, V90I, V118VI, D123E, D177E, I178LV, G196E, E204K, Q207E, R211K, L228R, A272P, K275R, Q278HY, T286TA, E297K, K311R, Q334P, M357T, A376T, K390R	B
	167699	167699	JN670158	NRTI	NNRTI	K65KR	K103N, Y181C, G190A, P225H	V35I, S68G, V90VI, K122E, D123E, I135T, K166R, I178M, G196E, A272P, P294S, E297R, V314A, M357T	B
	169047	169047	JN670189	NRTI	NNRTI	M41L, V75I, M184V, T215Y	K103N, P225H	E6EK, K20R, V60I, K122E, I132L, I135T, K173Q, T200I, R211K, A272P, L283I, I293V, P294PS, E297R, G335D, A355T, R358K, G359S, T386I, K390R	B
	169083	169083	JN670192	NRTI	NNRTI	M184V, T215Y	K103N, P225H	K20R, K101Q, D123E, I142V, S162C, E169D, I178L, G196E, T200A, E203K, E204D, A272P, V276I, I293V, I329L, G333DE, E344D, M357S, T369V, P392PT	B
	170328	170328	JN670218	NRTI	NNRTI	D67G, K70R, K219Q	K103N, Y181YC, P225H	S68G, R83RK, V90VI, D123E, D177E, G196E, Q207E, R211K, L228LR, V245E, A272P, K281R, I293V, E297K, Q334N, G335S, K366R, T369V, A371V, I375V, A376T, T377L, T386A, K390R	B
	177430	177430	JN670439	NRTI	NNRTI	M184V	K103N, P225H	V35T, K64KR, I135L, V245E, A272P, K277R, T286A, I293V, E297K, R356RK, A376V, T386A, Q394LS, E399D	B
	177433	177433	JN670440	NRTI	NNRTI	M41L, L74V, L210W, T215Y, N348I	K103N, Y181C, G190A, P225H	T39TA, K43KN, V118VI, S162A, Q174H, Q197H, E203A, Q207E, R211K, Q242K, K277KR, I293V, T296S, E297K, H315Y, I326V, Q334L, R356K, K366R, E399D	B
	180171	180171	JN670542	NRTI	NNRTI	Q151QL, M184V, N348I	K103N, P225H, K238T	K20R, V35IT, K64R, D123E, I142IL, Y146YH, V148VE, W153WS, K154KI, Q197E, T200A, R211G, E297EK, K311R, A360T, V365I, E370AG, A376S	B
	180716	180716	JN670555	NRTI	NNRTI	V75M, M184V	K103N, P225H	M16V, D123E, I135L, A158S, R211K, K238R, V245K, A272P, K281R, I329IV, G333E, Q334L, R356RK, M357T, T369AV, K390R	B
	180895	180895	JN670556	NRTI	NNRTI	M184V	V179D, G190A, P225H	V35T, K101KQ, K102Q, I142IV, I178L, V189VI, Q207R, R211E, V245M, I293V, E297R, Q334N, S379G, V381I, T386I, K390R	B
	181255	181255	JN670570	NRTI	NNRTI	M184V	K103N, P225H	K20R, V35T, K122R, I135L, A272P, V276I, E297K, Q334H, F346C, T377I, K390R, Q394S, K395R	B
	182682	182682	JN670623	NRTI	NNRTI	M184V	K103N, P225H	I135LV, I142T, E169D, D177G, T200A, A272P, K281R, T286A, I293V, E297K, V314I, Q334C, T338S, R356K, K366R, A376T, T386A, K390R, Q394S, E399D	B
	183910	183910	JN670664	NRTI	NNRTI	M184V, N348NI	K103N, P225H	I31L, S68G, V90VI, R211K, L228LR, V245M, E248D, S251I, V276I, T286A, V317VA, L325LI, I326V, M357T, V381I, I382IT, K390KR	B
	184640	184640	JN670684	NRTI	NNRTI	M184V	Y188L, P225H	V35T, V60I, A98S, T139K, V179VI, R211K, F214FL, P243Q, S251D, A272P, T286A, E297K, I329L, R358K, V365I, V372I, A376S, K395R, E399D	B
	184703	184703	JN670686	NRTI	NNRTI	M184V	V106VA, G190GA, P225H	K101KQ, I142IT, G196E, R211A, A272P, K281R, E297KR, Q334E, F346CY, G359GS, A376S, K390R, A400AT	B
	184847	184847	JN670688	NRTI	NNRTI	M41L, M184V, T215Y, N348NI	K103N, P225H	K20R, K22KR, K102M, I142IV, F160FL, G196E, T286A, I293V, E297A, K311R, G333E, A360T, Q367M, A371V, A376S, K390R	B
	185104	185104	JN670697	NRTI	NNRTI	M184V, T215Y	K103N, P225H	V35T, S68G, D123E, I135L, N175Y, I178IV, K201M, V245Q, A272P, K277R, K281R, E297K, R358K, G359S, A376S, K390R, E399D	B
	186778	186778	JN670722	NRTI	NNRTI	T69DN, M184V	L100I, K101E, P225H	E28K, V35T, K49KR, L228R, V245K, A272P, K281R, I293IV, E297K, N348H, M357T, E370EG, E399D	B
	186960	186960	JN670725	NRTI	NNRTI	M184V	A98AG, K103N, P225H	K20KR, V35T, I135L, D177NS, I178IM, T200A, K223E, A272P, K281R, T286A, I293V, E297K, M357MT, A376T, K385R, T386A, K390R, Q394S, E399D	B
	190350	190350	JN670796	NRTI	NNRTI	V75I, M184V	K103N, P225H	K49R, V60VI, K102R, V118I, K122E, I132L, I135V, D177S, I178ILM, T200A, F214L, A272P, L283I, R284K, I293V, E297K, I329L, Q334S, R358K, T377M, I382T, K390R, Q394L, E399D	B
	191361	191361	JN670824	NRTI	NNRTI	M41L, M184V, T215Y	K103N, P225H	V35R, K101Q, I135L, S162Y, P170S, P176PQ, G196E, Q197K, T200A, R211K, A272P, V276I, K281R, L283I, T286A, I293V, P294T, E297K, K311R, Q334G, R356K, K366R, Q394S	B
	191506	191506	JN670828	NRTI	NNRTI		K103N, P225H	E28A, V35T, V60I, K122E, I135C, I142V, S162F, G196E, K249Q, A272P, V276I, K277R, T286A, E297K, E312D, I329L, M357T, A376S, T377I, Q394L	B
	192043	192043	JN670843	NRTI	NNRTI	M41L, L74I, M184V, T215Y	K103N, V108I, P225H	K20R, E44D, V60I, S68G, V189I, T200A, H221Y, A272P, K277R, T286A, A288T, E297A, I326IV, A355AT, A360T, K366R	B
	192843	192843	JN670868	NRTI	NNRTI	M41L, D67N, K70R, T215F, K219E	L100I, K103N, P225H	K20R, V35T, T39TA, V60I, T69TN, I135V, P157A, S162T, T200A, R211K, L228H, V245T, A272P, K281R, E297K, I329L, A376T, Q394L	B
	195254	195254	JN670973	NRTI	NNRTI	M184V	K103N, P225H	V35T, H96HQ, T200A, R211T, V245M, L260F, A272P, K277R, I293V, P294S, E297K, L301LAPV, A304E, I326IL, I329L, Q334E, N348H, R358K, V365I, E370G, T377TA, P387PL	B
	196719	196719	JN671037	NRTI	NNRTI	M184V	K103N, P225H	I135L, F160I, S162SC, T200A, E204A, F214L, A272P, T286P, I293V, P294T, I326IV, Q334L, M357T, R358RK, K366R, Q394QL	B
	197356	197356	JN671069	NRTI	NNRTI	M184V, K219R	K103N, P225H	K20KR, E28A, K32KN, K101Q, I135T, T200E, R211K, F214FL, V245Q, E297K, A327V, I341F, G359S, T369V, A371V, I375V, A376S, S379G, V381I, T386I, K390R	B
	197920	197920	JN671095	NRTI	NNRTI	M184V, N348I	K103N, V108I, P225H	V35T, V60I, K64KR, K122E, D123A, I135V, T139K, Q207E, L260I, A272P, T286A, E297K, D324E, I329L, K366R, Q394L, E399D	B
	198046	198046	JN671098	NRTI	NNRTI	D67G, T69DN, K70R, K219Q	K103N, P225H	V60VI, K122E, I135T, D177E, T200I, R211K, F214L, V245M, A272P, I293V, E297A, Q334E, M357T, K366R, E399G	B
	199283	199283	JN671160	NRTI	NNRTI	L74V, Y115F, Q151M, M184V, K219E	K103N, V108I, Y181YC, P225H	S68G, T69S, W88S, V90I, K102Q, S117T, D123E, I142V, S162Y, I178L, T200A, F214L, V245E, A272P, K277R, K281R, I293V, E297K, A360AT, K390R	B
	202348	202348	JN671268	NRTI	NNRTI	M41L, L74V, M184V, T215Y	K103N, P225H, K238T	K20KR, V35T, T39M, V60VI, D177DE, I178M, T200K, Q207QK, R211A, A272P, K281R, T286A, P294T, E297KR, D324E, Q334S, G335GD, M357T, G359S, A376T, S379C, I382L, T386A, K390R, Q394L	B
	202350	202350	JN671269	NRTI	NNRTI	D67G, K70R, T215F, K219E	K103N, P225H, K238T	V35I, V60I, S68G, A98S, V118I, I135T, Q145M, T200A, F214L, E224K, A272P, Q278H, K281R, T286P, I293V, E297K, K311R, I382V, K390R, Q394L, E399D	B
	203106	203106	JN671298	NRTI	NNRTI	M184V	K103N, P225H	E6D, V35M, I135M, K173E, E204Q, E248V, A272P, K277R, I293V, G359S, A371V, I375V, A376S	B
	204298	204298	JN671336	NRTI	NNRTI	M184V, N348NI	K103N, P225H	V35T, K101Q, D123E, D177N, V189I, Q242QR, D256DE, A272P, K277KR, Q278QE, I293V, E297K, G333GR, G352GV, K366R, A376AT, I382IL, K395KR	B
	204728	204728	JN671347	NRTI	NNRTI	F116Y, Q151M, M184V	A98G, K103N, P225H	V35T, T39M, E53D, S68G, D123E, I135L, I142T, S162SN, I178L, T200A, F214FL, V245M, A272P, V292I, I293IV, E297A, M357T, A376T, S379SC, T386I, K390R	B
	205873	205873	JN671376	NRTI	NNRTI	M41L, D67DN, K70KR, M184V, L210W, T215Y, K219KE	K103N, V108I, P225H	K20R, V35M, E53D, K122E, I135IV, D177E, I178M, V189I, G196E, R211RK, A272P, T286A, R358K, T369V, S379G, K390R	B
	206033	206033	JN671384	NRTI	NNRTI	M41ML, K70KR, M184V	A98AG, K103N, P225H	L34F, V35VAIT, E36EA, K122E, D123DN, I135T, T200TI, A272P, K281KR, T286P, I293V, E297K, E300ED, K311R, M357I, R358K, A376T, T386TS, E399D	B
	207618	207618	JN671440	NRTI	NNRTI	M184V	P225H	V35VI, K102Q, D123E, I178M, R211K, I257L, A272P, K281R, E297K, I329L, Q334E, M357V, A376S, T386I	B
Melikian (2012)	CA1329	CA55164	GQ210380	D4T, 3TC, AZT, Unknown	EFV, Unknown	M41ML, M184V	K103N, P225H	V35R, T39A, K102Q, D123E, I135T, I142V, S162C, T200A, V245T, A272P, I293V, E297K	B

Reverse Transcriptase Inhibitors

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