<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation E138A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 31
Patients 150
Isolates 165
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Bacheler (2000)LB3-P26P26-1 NRTIEFVM41L, T215Y R83K, D121Y, K122E, E138A, S162C, R211KB
  P26-16 NRTIEFVK70RK103N, Y188LD121Y, K122E, E138A, S162C, T200A, E224DB
  P26-23 NRTIEFVD67N, K70RK103N, Y188LD121Y, K122E, E138A, S162C, T200AB
 LB3-P98P98-16 NRTIEFVK70RK101E, K103NY56C, D123E, E138A, I178M, V179IB
  P98-24 NRTIEFVK70RK101E, K103ND123E, E138A, I178M, V179IB
  P98-33 NRTIEFVK70RK103N, P225HD123E, E138A, I178M, V179IB
  P98-41 NRTIEFVK70RK103N, P225HD123E, E138A, I178M, V179IB
  P98-45 NRTIEFVK70RK103N, P225HD123E, E138A, I178M, V179IB
Shulman (2000)CA1158CA10467AY802645AZT, DDI, 3TC, ADVNVP, EFVM41L, V75L, L210W, T215YK103N, G190AK43N, K122E, E138A, I142V, S162C, R211Q, L228R, K277R, Q278HB
  CA8194AY802646AZT, DDI, 3TC, ADVNVP, EFVM41L, L210W, T215YG190AK43E, K122E, E138A, I142V, S162C, R211Q, L228RB
  CA10931AY802647AZT, DDI, 3TC, ADVNVP, EFVM41L, V75L, M184V, L210W, T215Y K43N, K122E, E138A, I142V, S162C, R211Q, L228R, K277R, Q278HB
Bacheler (2001)DMP003-2603-26125AF349331NRTIEFVK70RK103N, Y188LK20KR, D121Y, K122E, E138A, S162C, T200AB
Dunne (2001)ALD-pt1ALD-pt1AF369796NRTINNRTIM41L, D67E, T69S_SG, K70R, V75M, T215YG190QK122KE, I135T, E138A, P157PA, S162CY, P170PL, H208Y, R211K, A272P, K277R, V317AB
Gonzales (2001)CA1158CA2633AY030467AZT, DDI, 3TCNVPM41L, V75L, M184V, L210W, T215Y K43N, K122E, E138A, I142V, S162C, L168LF, R172X, V179VA, I180X, T200X, R211Q, L228RB
 CA1854CA4969AY030758D4T, 3TCDLV K101EA98S, D123E, E138A, I142V, T200AV, V245M, K259K*, A272P, K277R, I293VB
 CA3932CA9140AY030931DDC, AZT, D4T, 3TC, DDINVP, DLVM41L, D67DN, L74LI, M184MV, L210LW, T215SYA98G, K101EK32KN, V35I, R83K, V106I, V118VI, D123E, I135T, E138A, T200A, E203K, Q207QE, H208HY, R211K, K223KE, T286A, A288S, E297KB
 CA3937CA9147AY030936AZT, DDI, 3TCNVPL74V, M184V, L210LW, T215YK101E, Y181C, G190AV21I, T27X, M41MI, K43KR, V60I, K122P, I135T, E138A, I142IV, S162C, Q207E, H221HY, L228LR, A272P, K277KR, T286A, E297KB
 CA4115CA9420AY031105AZT, 3TC, D4TEFVM41ML, M184V, T215YL100LI, K101KE, K103NK20R, V35L, K43KE, A98S, K122E, E138A, G190X, G196E, I293VB
 CA4337CA10532AY031201D4T, 3TC, DDINVP K101E, G190AA98S, D123E, E138A, I142V, V179I, T200I, V245MT, A272PB
 CA4822CA11732AY031481AZT, D4T, 3TC, DDINVPM41L, L74V, L210W, T215YY181IK20R, T39A, K122E, I135T, E138A, S162C, V179VI, E203K, R211K, H221HY, D250NB
 CA5319CA13031AY031874AZT, 3TC, D4T, DDIEFVM41L, T215FYA98G, K103NS68SG, I135L, E138A, K154KQ, Q197EB
Margot (2002)MM-3159366433159366431 NRTINNRTID67N, K70R, M184V, K219Q K20R, V60I, T69N, E138A, T139I, T200A, Q207E, A272S, I293V, E297A, E298D, V317A, I329L, T338S, E344D, A355T, V365I, A376S, V381I, K390RB
 MM-2149365662149365661 NRTINNRTIM41L, A62AV, D67N, T69D, L210W, T215Y T7TS, M16V, K20R, T39TA, K43Q, E44D, R83K, V118I, K122KE, E138A, K166R, G196E, Q207E, H208Y, R211K, Q278H, T286A, T296S, E297K, I329L, Q334QH, G359S, T369V, A376V, T386AB
 MM-5212366215212366211 NRTINNRTIM184VV179DK20R, V35I, R83K, I135T, E138A, T165I, E169D, G196E, I202V, Q207N, R211K, I293V, E297T, L310I, Q334L, P345Q, M357T, T386I, K390RB
Gonzales (2003)CA1158CA20135AY305906AZT, DDI, 3TC, ADV, D4TNVP, EFVM41L, M184V, L210W, T215YK103N, Y188LE42EA, K43N, K122E, E138A, I142V, S162C, I202V, R211Q, L228R, V245VEB
Gonzales (2003)CA3932CA14759AF514161DDC, AZT, D4T, 3TC, DDI, ADV, ABCNVP, DLV, EFVM41L, D67N, L74V, L210W, T215YA98G, K101E, V108VI, V179VF, Y181YC, G190AP1S, V35I, E44ED, R83K, V106I, V118I, D123E, I135T, E138A, V189VI, Q197QH, T200A, E203K, Q207E, H208Y, R211K, K223E, T286A, A288S, E297KB
Dumans (2004)276276AY390131AZT, DDI, 3TC, D4TNVPM41L, D67N, M184V, L210W, T215YK101E, Y181C, G190AK43Q, E44D, A98S, K122E, D123N, I135T, E138A, I202V, H208Y, R211K, H221YB
Gomez-Carrillo (2004)9653396533AY365533NRTINNRTIM41L, D67N, V75M, L210W, T215Y, K219N V35I, T39TP, K43E, E44A, R83K, D123E, N136NT, E138A, T139TP, I178L, T200A, H208Y, R211K, V245VE, A272P, T286A, E297T, G335DE, R356K, M357T, A360AV, K390RB
 9827298272AY365573NRTINNRTIM41L, L74V, L210W, T215YK103N, Y188LV60I, K122E, E138A, I142V, G196E, R211K, V245K, V292I, I293V, E297K, Q334D, T351A, R356K, T386I, K390R, E399DB
 9890598905AY365589NRTINNRTIM184V, K219R K20R, K122E, E138A, I142T, T200V, R211K, V245T, I293V, P294T, E297Q, I329L, F346L, R358K, E370D, A376S, T377L, T386IB
 105322105322AY365723NRTINNRTID67DN, T215TFISK103N, G190AV60I, D121Y, K122E, I135V, E138A, I142V, A272P, K281R, I293V, E297K, Q334D, A371AV, K390R, Q394S, K395R, E399DB
 106532106532AY365750NRTINNRTIM41ML, V75T, Y115F, M184V K20R, K49R, K122E, E138A, E169D, I202V, R211K, V245M, A272P, K277R, I293V, P294S, E297R, Q334E, K366R, A376T, S379SG, T386IB
 107167107167AY365764NRTINNRTIM41L, D67N, T69D, K70R, M184V, L210W, T215Y, K219QK101E, G190SV60I, V90I, V118VI, K122E, I135T, E138A, S162N, G196E, R211K, L228H, A272P, E291D, M357T, A360V, A376SB
 108438108438AY365787NRTINNRTI K101E, Y181IK20R, T27S, V35M, T69A, R83K, D123E, E138A, V179I, T200A, A272P, K281R, E291D, I293V, E297A, D324DE, M357T, E399DB
 108821108821AY365797NRTINNRTID67N, K70R, M184V, T215F, K219Q K20R, V60I, I135T, E138A, Q207D, R211K, T286A, E297A, D324E, I326V, R356K, T369I, A376T, T386IB
 111946111946AY365855NRTINNRTIM184V, N348IK103NK20R, K49R, V90I, K122E, I135T, E138A, S162D, E169D, T200A, I202V, R211K, V245M, A272P, K277R, T286P, I293V, P294S, E297R, Q334E, K366R, S379G, T386VB
 114724114724AY365911NRTINNRTI  K64KR, D121H, K122E, E138A, I142V, T200TA, R211K, E248N, I293V, A376S, S379G, T386IV, K390RB
 117782117782AY365940NRTINNRTIM41L, D67N, M184V, T215YV179VEK43E, R83RK, K102Q, E138A, I142IV, S162A, I202V, R211K, A272P, V317VA, R356K, G359S, A376AS, T377LQ, K390RB
 118747118747AY365954NRTINNRTIM41L, D67H, L74V, V75M, L210W, T215Y, K219N, N348NIG190EK20R, T39A, E44D, K66N, T69N, K101R, K103R, V118I, K122E, E138A, I142V, S162C, T200A, L228H, T286A, I293V, E297R, I329IV, Q334E, I341IF, G359S, K395KRB
Gulick (2004)RG119RG119w43 ABC, AZT, 3TCEFVM184VK103N, Y188LV118I, K122E, I135V, E138A, S162C, R172K, K173T, Q174K, I178IM, V179I, T200A, Q207E, F214LB
 RG178RG178w102 ABC, AZT, 3TCEFV K103NS68G, D123E, I135T, E138A, Q174QR, D177E, I178IM, V189VI, R211KB
 RG366RG366w26 ABC, AZT, 3TCEFV  I37X, K102Q, K122E, E138A, S162C, I178M, V179I, G196E, T200TA, E204A, Q207QR, R211SB
 RG411RG411w47 ABC, AZT, 3TC, TDFEFV G190GAR83K, D123E, E138A, I142T, T165I, G196E, T200TI, R211KN, A272P, K277R, Q278H, I293V, E297DNB
Montes (2004)MB_patSLI00_SLI725AJ578161AZT, 3TCNVPD67I, M184VG190AK122E, E138A, E169G, H208P, D237NB
Mo (2005)92009200_d340 NRTINVPM184MV A98S, D121Y, K122E, I135L, E138A, V179I, Q207E, R211K, P243S, V245E, E297AB
Non-B Workgroup (2005)TH_404TH_404 AZT, DDIEFVD67N, K70R, T215F, K219EK103N, Y188LK122E, I135V, E138A, S162C, V245IB
Rhee (2005)CA1158CA34949AY800780AZT, DDI, 3TC, ADV, D4TNVP, EFVM41L, L210W, T215YK103N, Y188LP1L, K43N, K122E, E138A, I142V, S162C, R211Q, L228R, V245E, K277R, Q278H, I293V, E297AB
  CA48178AY800781AZT, DDI, 3TC, ADV, D4T, TDFNVP, EFVT215Y E138A, I142V, S162C, R211Q, K277R, Q278H, I293V, E297AB
 CA5319CA24202AY801548AZT, 3TC, D4T, DDI, ABCEFVM41L, T69S_SS, L210W, T215YA98G, K103NI135L, E138A, Q197E, H208HY, R211X, A272PB
 CA6868CA16939AY801722AZT, 3TC, D4T, DDC, DDIEFVM41L, D67N, K70R, L210W, T215FY, K219E K20R, V35L, T39A, E53D, V118I, K122E, E138A, S162C, F171Y, G196E, T200A, R211K, E248Q, A272P, K281KE, L283I, R284K, I293V, E297K, A299AGB
 CA7988CA35156AY801885AZT, 3TC, D4T, DDIEFV, NVPD67N, K70R, L74V, T215TI, K219QK103N, V108I, K238TK20R, V35IM, T39A, V60I, K64H, T69N, S105A, I135T, E138A, I202V, F214L, H221Y, L228H, T286A, I293VB
 CA8423CA21176AY8020073TC, D4T, DDIEFVD67G, K70KR, L74V, K219NG190EV60I, S68G, I135V, E138A, K173E, I178M, R211A, V245E, E248D, D250E, A272P, T286AB
 CA9755CA35117AY802102AZT, 3TC, D4T, DDIEFV  K20R, V35T, V60I, K122E, I135T, E138A, R211K, F214LB
Rodrigues (2005)BR0243902AY643223NRTI, UnknownNNRTI, UnknownV75M, F77L, F116Y, Q151M, M184VK101E, K103N, G190AK20R, K22R, S68G, K102Q, S105T, K122E, I135T, E138A, S162C, F214L, D218E, V245M, A272P, K277R, A288S, I293V, E300EKB
Baxter (2006)12-13591359-30729DQ879435NRTINNRTIL210LW, T215TS, K219KNL100LI, K103KNT39TA, K43KE, V60I, R83RK, W88WC, I135IV, E138A, I202IV, R211K, V245EKB
 12-19271927-30527DQ879878NRTINNRTID67N, K70R, F77FL, F116Y, Q151M, M184V, K219QK103N, Y188YHV60I, K122E, I135T, E138A, S162C, Q197E, F214LB
 12-22512251-30730DQ880130NRTINNRTI  S48T, D121DH, K122E, I135T, E138A, K173KR, I178IM, T200A, I244VB
 12-20772077-30609DQ879998NRTINNRTIM41L, D67N, L210W, T215Y, K219KRK103N, Y188LK43Q, E44D, S48T, V60I, A98S, V118I, K122E, I135MT, E138A, G196E, R211N, E224EDB
 12-40084008-30129DQ880392NRTINNRTIA62AV, K65KR, K70KR, V75VI, F77FL, F116FY, Q151LM, M184MV, T215TFISY188LS68SG, T69TN, K101R, K122E, E138A, T139TA, I142T, S162SC, T165TI, I178IM, V179VI, I202IV, Q207D, R211KB
 12-21652165-30821DQ880069NRTINNRTIM41L, D67N, T69D, M184V, L210W, T215Y, K219RA98G, K103N, K238TT39E, E44D, V60I, I94L, V111I, V118I, K122E, D123N, I135L, E138A, M164L, K166R, K173KHNQ, V189VI, G196E, T200A, E203D, H208Y, R211KB
 12-10761076-30318DQ879200NRTINNRTIM41L, A62V, D67DE, T69AG_XX, M184I, T215YK101P, K103KNK43E, K122P, D123E, E138A, I142IV, D177G, R211RKB
 12-10821082-30328DQ879206NRTINNRTIM41L, D67N, M184V, L210W, T215Y E44ED, A98S, K122E, I135L, E138A, G196E, E203ED, H208Y, R211RK, V245QB
 12-13761376-30722DQ879449NRTINNRTIM41L, D67N, L210W, T215YK103NT39TA, K43KQ, V60I, V118I, K122E, E138A, S162C, T200A, R211TB
 12-15721572-30508DQ879590NRTINNRTIM41L, D67N, L74I, V75T, L210W, T215Y, K219NA98G, L100I, K101E, G190A, F227LT39TA, K43Q, E44D, R83RS, W88C, V118I, K122E, S134SN, E138A, G196GE, E203K, H208Y, R211K, K223E, L228HB
 12-20782078-30612DQ879999NRTINNRTIM184V E138A, S162C, I178M, D192H, G196E, Q207E, F214LB
 12-17461746-30416DQ879736NRTINNRTI K103NT39A, V90VI, V106I, K122E, I135L, E138A, E204D, R211K, I244VB
 12-17441744-30522DQ879734NRTINNRTIM41L, D67N, K70R, T215F, K219EK103N, Y188LV60VI, A98S, K122E, D123E, I135V, E138A, G196E, T200I, I202V, L228R, V245MB
 12-11681168-30505DQ879280NRTINNRTIM41L, D67N, T69D, V75M, M184V, L210W, T215YA98G, K103N, Y188FK43E, E44A, V60I, R83K, V118I, K122E, I135V, E138A, S162C, G196E, R211K, V245MB
 12-21492149-30813DQ880056NRTINNRTIM41L, D67G, L74V, M184V, L210W, T215Y, K219NK101E, Y181C, G190A, M230LE44D, K64Y, S68ST, A98S, V118I, K122E, E138A, Q174HN, H208Y, R211K, W212M, D218E, L228LHB
 12-18181818-30728DQ879793NRTINNRTIM41L, V75M, M184V, L210W, T215YK103NT39A, K43EQ, E44D, K102R, V118I, K122E, E138A, R211KB
 12-31243124-30428DQ880346NRTINNRTIM41L, D67N, K70R, V75M, T215F, K219QK101E, K103NT39A, V60I, A98S, K122E, I135T, E138A, I142V, T200A, D218E, V245TB
 48-10111011-30610DQ880466NRTINNRTIM41L, A62V, D67E, L74I, V75T, L210W, T215DY, K219KNA98G, K101E, Y181C, G190GAS68G, V118VI, K122KE, I135T, E138A, S162A, R211KB
 48-10171017-30618DQ880472NRTINNRTIL74V, M184VK103NR83K, V90I, K102N, I135V, E138A, S162A, I202IV, R211K, K238KI, V245QB
 48-10721072-30625DQ880519NRTINNRTIM41L, D67N, K70R, L74V, Y115F, M184V, T215Y, K219QG190ST39M, K101D, D123E, I135T, E138A, R172K, D177E, I178L, V179T, D218EB
 48-10761076-30630DQ880523NRTINNRTI  R83K, D123E, E138A, T200AB
  1076-30925DQ880524NRTINNRTI  R83K, K102KR, D123E, E138A, T200A, R211RK, H235HLB
 48-10831083-30708DQ880529NRTINNRTI  D113DN, K122E, E138A, I142T, T200V, R211K, V245LMB
 48-10421042-30617DQ880491NRTINNRTIM41L, T69T_SS, T215YK101E, K103N, G190AK64KR, D121Y, K122E, E138A, I142T, D192N, T200A, R211A, Q222HB
 48-10221022-30617DQ880474NRTINNRTID67N, K70R, K219HQK103N, K238TD123E, E138A, S162C, E169D, D218E, L228RB
 48-11781178-30909DQ880585NRTINNRTID67N, T69D, K70R, M184V, T215F, K219QY181YFT39TA, K46KE, V60I, L109LP, F116FL, V118I, K122E, D123N, I135T, E138A, G196E, I202V, F214LB
 48-22292229-30922DQ877871NRTINNRTI Y188LV8VI, V35I, V60VI, R83K, K122E, I135V, E138A, K166R, G196E, Q197K, I202IV, V245VE, A272S, T286TA, A288S, K311KR, P345PT, M357TB
 48-30933093-30401DQ878000NRTINNRTIM41L, D67N, L74V, M184V, T215F, K219Q E6EG, K20R, K32KQ, T39A, V60I, T69N, V118I, K122E, I135T, E138A, K166R, Q174QR, V179I, I202V, R211K, F214L, A272P, K277R, I293V, P313PL, D324E, R356RK, A360T, T369TA, I375V, A376V, S379C, T386AB
 48-31273127-30401DQ878035NRTINNRTIM41L, D67DN, L74V, M184V, L210W, T215YK101EV35I, T39A, R83K, A98S, V118VI, K122E, I135V, E138A, Q174R, G196E, I202V, V245VE, A272P, A288S, E297KR, K311KR, D324E, I329L, Q334E, I341V, R356K, M357L, T362TS, K366KR, T369V, I375V, A376T, T377M, K390KRB
 48-32203220-30519DQ878127NRTINNRTIM41L, T215YK103N, P225HT39A, I135L, E138A, I142V, Q174R, T200A, R211K, T286A, E297K, K311R, R356K, K390R, I393M, A400ATB
 48-32313231-30520DQ878138NRTINNRTIM41L, D67N, T69~, L74V, M184V, T215Y, K219EL100I, Y188LT39S, S68G, K122E, E138A, S162C, S163I, Q197K, R211K, D218E, V245M, A272P, R284K, T286P, E297R, I326V, Q334E, M357T, R358K, T377K, E399DB
 48-32813281-30916DQ878188NRTINNRTIM41L, D67N, T69D, M184V, L210W, T215Y K20R, V35I, E44D, V118I, K122E, E138A, K166KQR, H208Y, R211K, A272P, K277R, T286A, A288T, E297K, F346HY, R356K, M357T, R358K, K390R, K395KRB
 48-40494049-30217DQ878282NRTINNRTIA62V, K70G, V75I, F77L, Y115F, Q151M, M184V S68N, K122E, E138A, R172RK, Q207QR, F214L, A272P, T286TA, A288S, V292I, I293V, E297K, K311KR, Q334HN, R356K, M357T, K366R, T369TA, E370ED, I375IVB
 48-41314131-30313DQ878362NRTINNRTIM41L, D67N, M184V, L210W, T215Y E44D, V60I, V118VI, K122E, I135V, E138A, I142T, S162C, L228LH, A272P, K277R, I293IMV, I326IV, A360T, E399DB
 48-41914191-30430DQ878424NRTINNRTIM41L, D67G, K70G, M184V, L210W, T215YV179D, Y318YFS68G, K102Q, K103R, K104KR, K122E, I135T, E138A, I202V, A272P, K281KR, A288S, V292I, I293V, S322T, P345Q, A376S, T386I, K390RB
 48-42244224-30616DQ878459NRTINNRTID67N, K70R, M184V, T215F, K219QK101EK20R, V21I, V35I, T69N, A98S, D123E, I135T, E138A, K173KR, I178IL, I202V, H208HY, R211K, V245T, R284K, T286A, A288S, E297K, M357T, E370D, A376ST, T377M, T386TP, K390RB
 48-43154315-30930DQ878528NRTINNRTID67N, K70R, T215F, K219QG190QK20R, K43Q, V60I, T69N, V118I, I135T, E138A, M164L, E203A, Q207E, F214L, L228LH, V245VE, A272P, K277R, E297EK, D324E, M357T, K366R, K390R, K395R, E399DB
 48-50485048-30515DQ878570NRTINNRTIA62V, T69G_SG, L210W, T215YA98G, K101E, V108I, Y181I, G190AK43E, K64R, W88C, K122E, E138A, K166R, T200A, I202V, E203K, L228H, A272P, K277R, T286A, E297K, A376V, T386IB
 48-50615061-30512DQ878578NRTINNRTIM184VK103NE6K, V35M, K122E, I135L, E138A, S162C, R211K, I293VB
 48-60456045-30515DQ878644NRTINNRTID67N, K70R, T215Y, K219E R83K, D123E, E138A, L228LF, A272P, K277R, T286P, E291D, E297K, I326T, Q334L, F346Y, A360V, A376AT, T377QB
 48-60586058-30715DQ878657NRTINNRTIK65KR, D67N, M184MI, T215L, K219QK101E, Y188LK20R, K22R, V60I, T69N, E79D, A98S, K122E, E138A, I202V, Q207A, F214L, H221HY, K223E, A272P, K277R, T286A, V292I, I293V, R356K, K388KRB
 48-60606060-30717DQ878658NRTINNRTIM41L, D67N, V75M, M184V, L210W, T215F, K219QV106A, G190A, F227FLK20R, V35I, T39A, V60I, T69TN, R83K, V90I, L109I, V118I, D123E, I135T, E138A, I202V, R211K, D218E, A272P, K281R, T286A, E297K, M357T, S379G, T386I, E399DB
 48-61216121-30807DQ878707NRTINNRTIM41L, M184V, L210W, T215Y, N348IK101E, G190AV35T, T39E, V60I, S68G, A98S, K122E, D123S, I135IT, E138A, T200TA, R211K, L228LH, D237E, A272P, I293V, E297K, T338S, A376T, T377TR, T386A, E399DB
 48-61836183-30721DQ878755NRTINNRTIT69DN, T215YK103N, M230LK102Q, E138A, I202IV, Q207A, R211K, F214L, A272S, L283I, I293V, R356K, G359GS, A371V, A376S, S379G, T386I, K390R, A400ATB
 48-62046204-30729DQ878777NRTINNRTIM41L, D67N, T69D, L210W, T215Y K20R, V35I, K43Q, E44D, A98S, V118I, D123E, E138A, K166R, K173T, D177DN, G196E, T200A, H208F, R211K, D250E, A272P, K277R, T286A, P294A, E297K, G335D, M357SB
 48-62076207-30715DQ878780NRTINNRTID67G, K70R, T215TI, K219QK101E, G190SK20R, V35M, T39A, E40D, V60VI, S68G, D123E, E138A, K173E, V179I, G196E, Y232YH, D237DN, A272P, K277R, A288AT, I293V, P294A, E297R, A360T, T386I, K390R, I393MB
 48-62206220-30730DQ878787NRTINNRTID67G, T69D, K70R, M184V, K219QK101EK20R, T39A, V60I, S68G, D123E, I135T, E138A, G196E, F214L, A272P, T286A, E297R, I326V, G335S, M357T, A371V, I375V, T386V, E399DB
 48-62286228-30807DQ878795NRTINNRTIM41L, D67N, K70KQ, V75M, F77L, M184I, L210W, T215Y K13KR, V21VI, V35M, K43KE, E44ED, V118I, D123E, E138A, D177DE, I178M, G196E, Q197EK, T200TA, E203K, H208Y, R211D, K223Q, A272P, K277R, R284K, T286A, E297A, G359S, A376S, S379SCB
 48-62606260-30828DQ878817NRTINNRTIM41L, M184V, L210W, T215Y E6D, E28EA, V35I, E44D, S48E, S68G, A98S, D123E, E138A, K166R, I178M, V179I, T200A, E248D, A272P, K277R, E297T, M357S, A360VB
 48-63306330-30924DQ878863NRTINNRTIM41L, D67N, K70R, T215Y, K219QV106A, G190AK20R, T39AS, V60I, K101Q, D123E, I135T, E138A, D177G, V179I, G196E, I202V, A272P, K281R, E291D, I293V, P294S, E297R, K311R, A371T, E399DB
 48-71507150-30825DQ878988NRTINNRTIM41L, L210W, T215Y, N348IK103NT39TA, K122E, E138A, A158S, E169D, Q174AE, I178M, V179I, A272P, V292I, I293V, K311R, Q334R, G335D, R358KB
 48-71967196-30729DQ879023NRTINNRTIM41L, D67N, L210W, T215Y V35VI, V60I, R83K, V118I, K122E, I135T, E138A, T200A, I202V, R211K, A272P, T286A, A371V, I375V, A376SB
 48-90619061-30820DQ880688NRTINNRTIM41L, D67N, M184V, L210W, T215Y, K219Q E40F, K43E, V111I, K122E, I135T, E138A, S162A, K173N, H208Y, R211KB
 48-90299029-30825DQ880668NRTINNRTI  S68SG, V118I, K122E, D123N, I135T, E138A, D177E, T200I, R211RK, F214LB
 48-92489248-30922DQ880843NRTINNRTI  T39A, K122KE, I135T, E138A, I142V, Q207E, R211K, F214L, V245IB
 48-90139013-30908DQ880653NRTINNRTIM41L, M184V, L210W, T215YK101KE, K103KNRS, G190GAK65KE, A98S, K122KE, D123E, I135T, E138A, Q174R, L187LS, G196GR, Q197E, R211K, P243H, I244IM, V245EB
 48-93269326-30929DQ880904NRTINNRTIM41L, M184V, T215YA98G, K101E, G190SV60VI, S68G, K122E, D123N, I135T, E138A, V189VI, T200A, E204D, Q207A, V245TB
 48-91529152-30826DQ880765NRTINNRTIM41L, D67N, M184V, L210W, T215Y K43N, E44D, A98S, V118I, D123E, I135T, E138A, D177E, I178IM, R211RKB
 48-90449044-30925DQ880681NRTINNRTIM41L, D67N, V75M, L210W, T215Y, K219NG190EK43N, E44AD, K101KQR, V118I, K122E, I135T, E138A, K166R, V179G, L187LS, I202V, R211KB
Margot (2006)96679667W144 D4T, 3TCEFV  I135L, E138A, S162A, I167V, V245Q, P294T, I329L, Q334E, Y339F, R356K, T369A, K374KR, I375V, T377I, K388RB
 72277227W48 D4T, 3TCEFV K101EK64R, A98S, D123N, E138A, I142T, R211Q, Q278H, T286A, P294S, E297K, S322T, I329L, A355G, A376VB
von Wyl (2007)454818485EF449929NRTINNRTIM184MVK103N, V108VIE6EK, K20R, R83K, K122E, D123E, E138A, K173Q, L210F, R211KB
Riddler (2008)RG8559RG8559w17 NoneEFV K103N, M230LK20R, T39A, K46Q, S68G, T69N, D123E, I135T, E138A, S162C, D177E, G196E, R211G, A272P, K277R, V317A, S322T, M357T, I375V, V381IB
Cardoso (2009)3107BRGO3107FJ638448NRTINNRTIM41L, L74V, M184V, T215YK101E, V108I, Y181C, G190AK20R, K32Q, K122E, E138A, H221Y, V245TB
Kagan (2009)22 NRTINNRTIM184V, N348IK101P, K103SK20R, V21I, V60I, K122Q, I135V, E138A, I178M, V179I, G196E, F214L, A272P, K277R, T286A, A288S, K323R, M357T, A376S, K390R, A400SB
Luo (2009)xf.102005HBxf.1020FJ375080NRTINNRTI  I135V, E138A, S162C, T200A, I274V, Q278E, Q334LB
Dau (2010)05499A05499AGU581662NRTINNRTIK70KR, M184V V35I, K64R, E138A, I142V, K173Q, Q174QK, D177G, V179I, A272P, K281KR, E297R, G333E, G335S, G359S, A371V, A376AT, K390R, E399DB
 06070A06070AGU581701NRTINNRTIM41L, D67N, T69D, M184I, L210W, T215YY188LE6K, T27S, V60I, V118I, K122E, I135V, E138A, E203K, Q207E, H208Y, R211K, K223E, V245EK, A288S, I293V, E297K, Q334E, G359S, A371V, A376CST, E399DB
 07215A07215AGU581824NRTINNRTIM184V, T215YK103NK20R, E138A, S162C, T200A, R211K, K277R, T286A, E297K, E312A, I326V, P345Q, N348T, A376S, T377L, T386IB
 07289A07289AGU581834NRTINNRTIM41L, T215Y, N348IK101P, K103NV21I, V118I, E138A, I142T, S162C, V179I, L210F, P243S, A272P, K277R, T286A, E297R, G333E, Q334H, G335C, M357T, K388KR, E399DB
 07444A07444AGU581847NRTINNRTIM41L, D67N, T69D, K70R, L74V, T215F, K219W, N348IY181V, G190EK11KR, V35VI, T39TA, K101T, V118VI, K122E, E138A, S162CY, R172RK, H208HY, L210LS, L228H, V245MR, R284K, A288S, I293V, E298A, E312A, I326V, Q334E, M357T, V365VI, A376T, T386A, K390KRB
 10546A10546AGU582009NRTINNRTID67N, T69D, K70R, M184V, T215V, K219QK101KE, G190AV35M, E36ED, V60I, R83RK, K122E, E138A, V179I, I202V, R211K, F214FL, D237E, A272P, K277R, I293V, P294PS, E297EK, D324DE, R356K, G359GRS, A360AV, A376SB
Aulicino (2011)ARL449AMAARL449AMAFJ525809NRTINNRTID67N, T69D, K70R, L74I, V75T, Y115F, M184V, T215V, K219Q V35I, T39A, V60I, K64H, T107P, K122E, D123N, I135L, E138A, T200AB
 ARN926MRDARN926MRDFJ525867NRTINNRTIM184V E40D, E44K, G45E, V60I, A98T, I135V, E138A, S162C, F171L, T200E, R211TB
 3214-N808CMN3214-N808CMNHQ158182NRTINNRTIM184VK101E, V108I, G190AV35T, K49R, V60I, K103R, D123E, E138A, E169D, D177E, I180V, T200AB
 7-K4757-K475HQ158261NRTINNRTID67N, T69D, K70R, L74I, V75T, Y115F, M184V V35I, T39A, V60I, K64H, K122E, D123N, I135L, E138A, T200AB
Bunupuradah (2011)079-004-005079-004-005 AZT, 3TCEFVM184V, L210W, T215YK103N, K238TK32N, V60I, S68G, A98S, K122P, I135L, E138A, I178L, V179L, Q207E, R211K, V245EB
 079-011-024079-011-024 D4T, 3TCNVPM184VK101E, G190AK122E, I135L, E138A, S162CB
Fourati (2012)1008024610080246JQ396162NRTINNRTIM41L, L210W, T215FA98G, K103NV35I, V60I, S68G, K122E, I135T, E138A, I142V, G196E, T200AB
 94007839400783JQ396158NRTINNRTIM41LW, L74V, M184V, T215YK103N, Y188LV35T, C38CS, T39A, G51R, P55PS, W88*, K122E, E138A, I142T, A158S, T165I, G196E, W212*, M230IB
 1034015010340150JQ396160NRTINNRTI  K122E, I135V, E138A, S162C, R211QB
Jones (2012)129357129357JN669467NRTINNRTIM41L, M184V, T215YV179DK20R, K103R, V111I, K122E, I135T, E138A, I142T, Q207K, R211S, F214M, V245T, V292I, I293V, E297R, I341V, A360T, A376V, T386I, K390RB
 130059130059JN669480NRTINNRTIL74V, M184V, N348IK103NR83K, V90I, K102N, I135V, E138A, S162A, I202V, R211K, A272P, K277R, E291D, I293V, M357T, A400ATB
 135338135338JN669541NRTINNRTIA62V, K70Q, V75I, F77L, Y115F, F116Y, Q151M, M184VV106M, V179D, G190AT7I, T58N, S68R, K103R, V118I, D121C, K122E, I135T, E138A, T165I, Q174K, D177E, G196GE, Q197LP, I202V, F214L, V245M, A272P, T286P, I293V, P294T, K311KR, Q334L, T338S, E370D, T386I, E399DB
 142746142746JN669624NRTINNRTIA62V, K70Q, V75I, F77L, Y115F, F116Y, Q151M, M184VV106M, V179D, G190AT7I, T58N, S68R, K103R, V118I, D121C, K122E, I135T, E138A, T165I, Q174K, D177E, G196E, Q197L, I202V, F214L, V245M, A272P, T286P, I293V, P294T, K311KR, Q334L, T338S, E370D, T386I, E399DB
 142777142777JN669626NRTINNRTIM41ML, D67N, T69D, K70R, T215F, K219QK101E, K103N, G190ST39A, V60VI, E138A, T139TA, F214L, A272P, K277R, R284K, T286A, I293V, E297V, I326V, A360T, A376S, T377QB
 143570143570JN669643NRTINNRTIM41L, L74V, M184V, L210W, T215Y V35VE, T39A, E44D, V118I, K122E, E138A, I142V, S162C, T200A, I202V, T286A, I293V, E297K, Q334E, G359S, S379CB
 153716153716JN669801NRTINNRTI K103NK20KR, K22KN, E138A, Q174QR, I178L, I180V, I270S, A272P, K281R, T286P, V292I, I293V, E297K, V317A, T377KQ, K390R, Q394L, E399EDB
 159853159853JN669967NRTINNRTIM41L, L74IV, M184V, L210W, T215YK101P, K103NE6K, K20R, K32R, V35M, A98S, K122E, E138A, R172K, D177E, I178IM, V179I, G196E, R211A, L228R, A272T, K281R, I293V, E297K, M357T, A376T, T386SB
 160145160145JN669970NRTINNRTIM41L, M184V, L210W, T215Y E6EK, W24W*, K43KE, S68G, K122E, I135V, E138A, V179I, G196R, T200D, R211K, V245E, E248D, T286A, V317A, L325I, I326IV, I329V, M357T, A371V, A376ASB
 160597160597JN669985NRTINNRTIM41L, D67N, T69D, V75M, M184V, L210W, T215Y, K219NY188LE40ED, V60I, V118I, K122E, E138A, I142V, G196E, H208Y, R211K, V245K, V292VI, I293V, E297K, Q334D, T351A, R356K, T386I, K390R, K395R, E399DB
 176698176698JN670410NRTINNRTIM41L, L210W, T215Y, N348IY181C, G190AT39K, K43E, E44D, K101Q, V118I, E138A, G196E, E203EA, H208Y, R211K, L228R, Q242L, I270IV, A272P, K281R, T286P, A288AT, I293V, E297K, D324E, M357T, A376S, K390R, Q394LB
 177876177876JN670467NRTINNRTID67N, K70E, V75TK103N, Y181C, G190AE6EK, V111VIM, K122E, E138A, I142T, P157A, A158S, G196E, L210F, R211K, F214L, H221Y, E248D, Q278H, T286A, I293V, S322SA, I329L, G335S, F346Y, R356K, V365I, T369V, A376S, T377L, K390R, A400PSB
 180281180281JN670543NRTINNRTID67N, M184V, T215Y, K219E K20R, V35I, E44D, S68G, D123E, E138A, T200S, I202IV, R211K, R284K, T286A, E297R, V317VA, D324E, I329L, F346Y, A360T, K390RB
 182631182631JN670619NRTINNRTIM41L K11T, V60I, K122E, I135T, E138A, I142V, G196E, I202V, R211G, V245E, E248D, K277R, T286A, V292I, I329L, M357T, T386I, E399EK, A400SB
 182834182834JN670626NRTINNRTID67N, K70R, L74V, M184V, K219QL100I, K101E, K103NTV35L, T39A, V60I, R83K, I135T, E138A, D192N, I293V, E297Q, V317A, D324E, I329L, A360T, V365I, K390R, E399EKB
 184770184770JN670687NRTINNRTIM41L, L74V, V75I, M184V, L210W, T215YL100I, K103N, Y181IV60VI, F87FL, K122E, I132L, I135T, E138A, V179I, G196E, I202V, R206K, Q278QH, A288S, I293V, M357V, A376V, T386IB
 193886193886JN670915NRTINNRTIM41L, D67N, K70R, T215F, K219EK101E, Y188L, G190AV60I, K122E, I135IT, E138A, I142T, F214L, K275R, K277R, Q278H, K281R, V292I, I293V, E297A, G359NS, A360T, K366R, T386IB
 194216194216JN670927NRTINNRTIT215TNSYK101E, G190AV60I, I135L, E138A, I178IM, V179VI, R211K, D237DE, A272P, K277KR, E297V, L325I, I341L, G359S, A360T, A376S, T377M, T386IB
 195399195399JN670979NRTINNRTIM41L, M184V, T215CK101E, V179D, G190AT39TA, K103KR, K122E, E138A, I142IV, D177DN, I178M, V245K, A272P, K277R, I293IV, E297A, S322T, Q332H, R358RK, G359GS, K366R, K390RB
 197105197105JN671061NRTINNRTI  E6D, K22R, W88WC, E138A, I142T, K166R, K173EQ, V179I, I202V, A272P, K277R, T286P, A288S, V292VI, I293V, E297A, D324E, K347Q, R356RK, K366R, A376VB
 198158198158JN671106NRTINNRTIM41L, D67N, M184V, L210W, T215Y T39A, E44D, S48E, K64Y, W88S, V118I, E138A, S162Y, T200I, Q207E, R211K, V245E, T286A, A288S, E297A, I326IV, Q334E, Y342F, A376S, T386I, K390R, E399EKB
 200084200084JN671190NRTINNRTIM41L, D67N, T69D, V75M, M184V, L210W, T215Y, K219NY188LT39A, V60I, V118I, K122E, E138A, I142V, G196E, H208Y, R211K, V245K, K281KR, T286TA, L289LI, I293IV, E297K, Q334D, T351A, R356K, T386I, K390R, K395R, E399DB
 206846206846JN671412NRTINNRTI  E6D, A98S, E138A, Q197K, R211K, P243S, V245E, A272P, I293V, P294Q, E297T, S322A, R358K, G359S, A376T, K390RB
 206880206880JN671416NRTINNRTIL74V, Y115YF, M184V, K219NL100I, K101E, G190AV35I, I135L, E138A, S162A, I167IV, V179I, R211X, H221Y, D237N, V245Q, A272P, A288S, P294T, I329L, Q334E, Y339F, R356K, I375V, T377L, T386I, K388RB
 207035207035JN671418NRTINNRTIL74V, Y115YF, M184V, K219NL100I, K101E, G190AV35I, I135L, E138A, S162A, I167IV, V179I, R211X, H221Y, D237N, V245Q, A272P, A288S, P294T, I329L, Q334E, Y339F, R356K, I375V, T377L, T386I, K388RB
Kouri (2012)CU1425-10CU1425-10JQ585428NRTINNRTI  V8VI, V35VI, D123E, E138A, I142IT, T165I, E169D, I178L, G196E, Q207E, F214L, V245KQ, A272P, K277R, I293V, I329LB
 CU9-11CU9-11JQ585472NRTINNRTI  K22R, K49R, V106I, D123E, E138A, I142V, T165I, E169D, I178L, Q207E, R211K, F214L, V245VM, A272P, K277R, L283I, I293VB
 CU1655-10CU1655-10JQ585439NRTINNRTIM41L, D67DN, M184V, L210W, T215YK101E, V106VA, F227FLK11R, K20R, E44ED, V118I, K122E, D123E, I135T, E138A, S162C, V179I, G196GAV, I202IV, Q207E, H208HY, R211K, A272P, I293V, P294S, E297R, E312T, Q334LB
Melikian (2012)CA25602CA79444GQ212822Unknown, TDF, 3TC, FTCUnknown, EFVM41L, D67G, L210W, T215Y, K219RK101EK20R, K43N, E44D, K64H, V118I, D123E, E138A, I178M, R211K, D218EB
Mollan (2012)MK71MK71w89 TDF, FTCEFV  K32KE, E36EK, R83K, K102Q, I135V, E138A, S162C, I178ILM, T200TA, R211RK, G231GS, P243T, E248D, A272P, K275R, K277R, Q278H, T286AB