Reverse Transcriptase Inhibitors

HOME Genotype-Rx Genotype-Pheno Genotype-Clinical hivdb program

Reverse Transcriptase Inhibitors

Subtype	B
Gene	RT
Mutation	K103S
Rx	>= 1 NNRTI (+/- NRTI)
IncludeMixtures	No

References	17
Patients	119
Isolates	124

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	NRTIs	NNRTIs	NRTIDRMs	NNRTIDRMs	OtherMut	Subtype
Hammer (1997)	ACTG320_753	753		AZT, DDI	NVP	D67N, T69D, K70R, T215F, K219Q	K103S, G190A	K101Q, K102Q, K122E, D123E, S162C, I178IM, V179I, T200A, R211K, A272P, V276I, Q278E, L283I, I293V, E297K, R356K, G359S, A371V, K390R, A400T, V435A, D460N, H483Y, D488X	B
Gonzales (2001)	CA4078	CA9364	AY031072	AZT, DDI, 3TC	NVP	D67N, T69D, K70KR, M184V, T215F, K219Q	K103S, G190GA	I178M, H208Y, R211K	B
	CA4366	CA10567	AY031225	AZT, 3TC, D4T, Unknown	NVP, Unknown	D67N, K219Q	K103S, G190A	V35T, T39TA, V60I, K102Q, D123E, I135L, S162A, T165I, D177A, G196E, N265NS, A272P, K277R, T286A, I293V, E297K	B
	CA5201	CA12503	AY031764	DDI, D4T, 3TC	NVP	M184V	K103S, G190A	K122E, D123E, S162SG, D177E, Q207A, R211K, K277R, T286A, E297K	B
	CA5484	CA13509	AY032023	3TC, D4T	NVP	D67N, K70R, M184V, K219Q	K103S, G190A	V60I, K173Q, R211A, F214L, L228H, V245Q, D250E, A272P, V276VG, T286A, E302ED	B
Margot (2002)	MM-242036622	2420366221		NRTI	NNRTI	M41L, L74V, M184V, T215Y	K103S, G190A	V35I, T39K, K43E, K102KR, V179I, T200A, R211S, K249Q, L283I, A288AWSG, V292I, I293V, E297A, P313PS, V317A, G333E, T338S, R356RK, M357T, T369V, K390R, E399D	B
	MM-409136768	4091367681		NRTI	NNRTI	M41L, D67N, K70R, T215Y, K219Q, N348I	K103S, G190GSR	I5IT, V35I, T39TA, V60I, G196E, T200I, E204Q, Q207D, R211RK, V245K, I293V, E297R, L301I, Q334E, R358RK, A360VI, T377R, K390R, E399D	B
	MM-235136685	2351366851		NRTI	NNRTI		K103S	K20R, V60VI, A158AS, R211RK, I293V, E297A, E344D, K350KR, T386V, K390R	B
Gonzales (2003)	CA1834	CA21085	AF514123	DDC, AZT, D4T, DDI, 3TC, ABC	EFV, NVP	D67N, T69D	K101P, K103S	V60I, D123E, I135T, I178M, T200A, Q207G, R211K, P294Q	B
Gonzales (2003)	CA5006	CA24397	AY305924	AZT, 3TC, D4T, DDI	EFV	D67N, K70R, T215TI, K219Q	K101P, K103S	V60I, T69N, K102KR, K104KR, K122E, I135T, S162C, F214L, D218E, V245VA, A272P	B
Garcia-Bujalance (2005)	GBS_07	GBS_07	AY872342	AZT, DDI, D4T, 3TC	NVP	M184V, T215F	K103S, G190A	K101R, L120I, D121Y, K122E, I135T, F214L	B
Rhee (2005)	CA1290	CA48090	AY800855	DDC, AZT, D4T, 3TC, DDI, ABC	NVP	M41L, D67N, L74I, M184V, T215F, K219Q	K103S	V118I, K122E, I178IM, V179VI, T200A, Q207EK, D218E, D250DA, A272P, T286TA, E297A	B
	CA1587	CA20239	AY801051	AZT, 3TC, D4T, DDI	NVP	M41L, M184V, L210W, T215Y	K103S, G190A	K20R, K43KE, E44ED, K49KR, I135T, D177DE, I178IM, R211RK, A272P, K275KR, K277R, T286A, E297K	B
	CA1600	CA23978	AY801061	AZT, DDI, 3TC, D4T, ADV	NVP, EFV	M41L, D67G, L74IV, M184V, L210W, T215Y, K219E	K101P, K103S, V108VI	V35M, T39A, E40F, K43E, V60I, S68G, R83RK, K104R, V118I, K122E, D177N, T200A, R211K, D218DE, L228H, T286A, E291D, E297K	B
	CA1834	CA23190	AY801090	DDC, AZT, D4T, DDI, 3TC, ABC	EFV, NVP	D67N, T69D, M184I, L210W	K101P, K103S	V60I, D123E, I135T, I178M, T200A, Q207E, R211K, P294Q	B
	CA4078	CA34294	AY801259	AZT, DDI, 3TC, TDF	NVP	D67N, T69D, M184V, T215F, K219Q	K103S, G190A	I178M, V179I, T200TI, H208Y, R211K, A272P, K277R, L283LI, I293V	B
	CA4366	CA24206	AY801313	AZT, 3TC, D4T, Unknown	NVP, Unknown	D67N, K70R, M184V, T215F, K219Q	K103S, G190A	V35T, T39TA, V60I, T69TN, K102Q, D123E, I135L, S162A, D177A, G196E, A272P, K277R, T286A, I293V, E297K	B
	CA5006	CA42714	AY801453	AZT, 3TC, D4T, DDI, ABC	EFV	M41ML, D67N, K70R, T215F, K219Q	K101PS, K103S	E28EA, I50IT, V60I, T69N, K102KQR, K104KR, V118VI, K122E, I135T, S162CY, F214L, D218E, A272P	B
	CA5058	CA23681	AY801471	AZT, DDC, D4T, 3TC	EFV	M41L, M184V, T215Y	K101P, K103S	T39A, R83K, K102KR, D123DE, S162F, V179I, E204Q, R211K, H221HY, D250E, A272P, T286A, A288P, E297R	B
	CA5305	CA15890	AY801544	Unknown, D4T, 3TC	Unknown, NVP	M184V	K103S, G190A	V35I, S68G, T69N, K102Q, S162C, V245Q, A272P, K277R, L283I, T286TA, I293V, E297A	B
	CA6814	CA34281	AY801705	D4T, 3TC, ABC	NVP	L74V, Y115F, Q151M, M184V	K103S, V106M	K102R, D177E, I178M, T200E, R211Q, F214FL, V245VE, A272P, I293V	B
	CA8444	CA21209	AY802021	AZT, 3TC, D4T, DDI	NVP	T215Y	K103S, G190A	V35VI, K122E, D123E, D177E, R211T, F214L, T286A, I293V	B
	CA14542	CA34907	AY802373	AZT, DDC, D4T, 3TC, ABC, DDI, TDF	NVP	M41L, D67N, T69D, K70R, M184V, T215F, K219Q	A98G, K103S, G190A	A33G, V118I, T200TA, R211K, F214L, L228X, A272P, I293V	B
		CA38271	AY802718	AZT, DDC, D4T, 3TC, ABC, DDI, TDF	NVP	M41L, D67N, T69D, K70R, M184V, T215F, K219Q	A98G, K103S, G190A	A33G, V118I, R211K, F214L, L228HKNQ, A272P, I293V, E297EA	B
Baxter (2006)	12-2254	2254-30710	DQ880131	NRTI	NNRTI	D67G, K70R, L74LI, M184V, T215I, K219Q	K103S, G190A, K238T	K64H, T69N, V118I, K122E, I135T, G196E, Q197K, T200A, F214L, L228H, V245K	B
	12-4043	4043-30305	DQ880412	NRTI	NNRTI	M41L, D67N, T69D, L74I, M184V, L210W, T215Y, K219KR	K103S, V108I, G190A	K43E, E44D, E53D, V118I, K122E, R172K, D177G, T200E, E203K, Q207E, R211K, K223Q	B
	12-1899	1899-30514	DQ879852	NRTI	NNRTI	M41L, D67N, V75M, M184V, L210W, T215Y, K219N	L100I, K103S, G190A	K43A, E44D, V60I, V118I, D121C, K122E, I135IT, D177E, G196E, T200I, R211K	B
	12-1901	1901-30605	DQ879854	NRTI	NNRTI	M41L, L74I, V75S, M184V, L210W, T215Y, K219N	K103S, V108VIL, Y181C, G190GA	T39A, K43Q, V118I, K122E, D123DN, S162SN, D192DN, G196E, T200A, R211K, D218E, L228HR, Q242L, V245VM	B
	12-2242	2242-30707	DQ880125	NRTI	NNRTI	M41L, D67N, L210W, T215Y, K219R	K103S, G190A	T39A, E44D, K49R, V60I, V90I, V118VI, K122E, D123E, S162D, E169D, Q207E	B
	12-2243	2243-30826	DQ880126	NRTI	NNRTI	D67N, K70G, L74V, Y115F, M184V, T215FL, K219Q	K103S, G190A	K65KE, D123E, I135T, K173KE, D177E, I202IV	B
	12-1827	1827-30528	DQ879796	NRTI	NNRTI	D67N, K70R, M184V, T215F, K219Q	K103S, G190A, K238T	K64H, T69NY, K122E, Q174QR, V179I, G196K, I202IV, Q207E, R211RK, L228Q	B
	12-1967	1967-30621	DQ879907	NRTI	NNRTI	M41L, L74I, V75T, M184V, T215Y, K219Q	K103S, Y181C, G190A	K122E, D123DGNS, I142V, D177E, I178M, T200A, Q207K, R211AT, F214L, D218E, L228R, V245VM	B
	12-1414	1414-30822	DQ879476	NRTI	NNRTI	M41L, D67N, T69D, K70R, V75M, M184V, T215F, K219Q	K103S, G190A	T39A, K43E, E44EA, V60I, V118I, K122E, D123N, I135T, S162D, V179VI, G196E, E203A, F214L, L228H	B
	12-2230	2230-30709	DQ880114	NRTI	NNRTI	M41L, D67E, K70KE, V75M, L210W, T215Y	K103S, G190A, K238T	T39A, E44D, S68G, K122E, S134G, E203D, Q207E, H208Y, R211K, V245K	B
	12-1762	1762-30417	DQ879749	NRTI	NNRTI	M41L, T69S_SS, V75M, M184MV, L210W, T215Y	K103S, V108I, G190A	T39A, D86E, W88C, L109I, D123E, I142V, R172K, V179I, Q197K, T200A, Q207E, H221Y	B
	12-2325	2325-30804	DQ880165	NRTI	NNRTI	D67N, K70KR, M184V, T215V, K219Q	K103S, G190A	T69N, K102Q, V179VI, T200IV, F214L, L228H	B
	12-2473	2473-30821	DQ880219	NRTI	NNRTI	A62V, T69S_VG, M184V, T215I	A98G, K103S, G190GA	K122E, I178IM, T200TA, V245E	B
	12-1779	1779-30605	DQ879764	NRTI	NNRTI	M41L, D67N, T69D, M184V, L210W, T215Y	K103S, V106A, G190A, F227L	K43Q, E44D, L109I, V118I, K122E, V179I, G196E, T200AE, E203K, Q207E, H208Y, R211K, H221Y, V245Q	B
	12-2157	2157-30619	DQ880063	NRTI	NNRTI	M41L, D67N, L74V, V75T, M184V, L210W, T215Y, K219DN	L100I, K103S	K102KR, V118I, K122KE, I142V, S162SN, T200TA, R211RK, V245T	B
	12-1438	1438-30811	DQ879497	NRTI	NNRTI	M41L, D67N, K70R, L74I, Y115F, M184V, T215F, K219Q	K101P, K103S	V60I, D123E, I135T, D177E, T200A, I202V, D218E	B
	12-1743	1743-30515	DQ879733	NRTI	NNRTI	M41L, D67N, T69D, M184I, L210W, T215Y, K219R	K101P, K103S	T39DE, E44D, V118I, K122E, T200TA, E203K, Q207QE, H208Y, R211K, K223Q, V245K	B
	12-1440	1440-30527	DQ879499	NRTI	NNRTI	M41L, K65R, K70R, V75I, F116Y, Q151M, T215F, K219E	K103S, V108I, Y181C, G190A	S68G, T69TI, L109I, V118I, D123E, I135T, T139I, T165I, Q174H, D177E, I202V, F214L, L228H, I244V, V245M	B
	12-2042	2042-30604	DQ879972	NRTI	NNRTI	M41L, D67N, T69DN, L74V, M184V, L210W, T215Y, K219Q	K101P, K103S	T39A, K43E, V118I, K122E, I142IT, Q174R, D177DE, I178M, V179I, D192N, G196E, E203K, Q207E, R211K, K223E, L228H	B
	12-1161	1161-30529	DQ879273	NRTI	NNRTI	A62V, K65R, K70T, L74LV, V75I, Y115YF, F116Y, Q151M	K103S, G190A	V60I, S68G, T69I, R83K, V118I, K122P, D123E, I135IT, T139I, R172K, Q174R, D177E, I178IM, D192DN, Q197E, E204K, Q207E, R211K, F214L	B
	12-1193	1193-30305	DQ879299	NRTI	NNRTI	D67N, T69D, M184V, T215I, K219Q	K103S, G190A	T39A, S48E, V60I, V118I, I135T, K166R, V179VI, E194K, G196E, F214L, L228H	B
	12-1640	1640-30320	DQ879644	NRTI	NNRTI	M41L, L74V, L210W, T215Y, K219N	L100I, K103S	V118I, K122E, T200A, Q207E, R211K	B
	12-1591	1591-30618	DQ879601	NRTI	NNRTI	M41L, D67N, K70R, V75M, L210W, T215F, K219E	K103S, G190GA	V60I, K122E, I135IMV, P170PL, R172RK, D177E, R211K	B
	12-3066	3066-30407	DQ880297	NRTI	NNRTI	M41L, D67N, V75M, M184V, L210W, T215Y, K219N	K101P, K103S	T39A, E44D, N54I, A98S, V118I, D123E, D177N, I178M, V179VI, G196GE, T200A, E203K, H208Y, R211K, W212C, K223Q	B
	48-2002	2002-30422	DQ877837	NRTI	NNRTI	M41L, D67N, L210W, T215Y	K103S, G190A	T39A, E44ED, V60I, V90I, V118I, K122E, I135T, I142V, S162A, V179VI, D237E, A272P, T286A, I293V, E297K, D324DE, G359S, A371V, E399ED	B
	48-3019	3019-30812	DQ877929	NRTI	NNRTI	M41L, D67N, K70GR, L74V, M184I, L210W, T215Y, K219Q	A98G, L100I, K103S	V35IT, K43N, V118I, D123E, I135T, T200A, E203K, H208Y, R211Q, D218E, K223Q, L228H, Q242H, D250E, A272P, T286A, E297K, S322T, I329IV, K350R, G359S, A371V	B
	48-3038	3038-30304	DQ877949	NRTI	NNRTI	M41L, D67N, K70R, V75M, L210*W, T215F, K219Q	K103S, G190A	K20R, K43N, V60I, K122E, I135M, A158AS, S162Y, T200TA, E203D, L228H, A272P, I293V, S322T, D324E, G335S, G359S, A371V, I375V, A376S, T377I, S379C	B
	48-3042	3042-30305	DQ877954	NRTI	NNRTI	M41L, M184V, L210W, T215Y	K103S	P4T, V35I, K43N, V118I, D123E, D177E, I178M, V189VI, T200A, Q207K, R211D, V245T, A272P, K277R, I293V, R307RK, Q334L, G359S, A371V, A376T, T386M	B
	48-3145	3145-30429	DQ878056	NRTI	NNRTI	M41L, D67N, M184V, L210W, T215Y	K101P, K103S	T27S, V35T, K43N, V60I, V90I, V118I, K122E, D123N, I135T, E138Q, N175Y, T200K, K201I, R211K, A272AP, T286A, E297A, D324E, I329L, A360AT	B
	48-3200	3200-30515	DQ878110	NRTI	NNRTI	M41L, D67N, T69D, V75M, M184V, L210W, T215Y	K103S	E6K, M16V, K20R, V35I, T39A, E40F, K43E, V118I, K122E, I135T, D177N, T200A, E203AT, Q207D, H208Y, R211K, A272P, T286A, A288S, Q334E, A355G, M357T, A371V, A376T, A400S	B
	48-3208	3208-30515	DQ878118	NRTI	NNRTI	M41L, D67N, T69D, L74I, M184V, L210W, T215Y	A98G, K103S, G190A	E6D, T7I, K43E, E53D, I94IL, K122P, I135T, I142V, S162HY, I167IV, V189I, I195IL, L228H, I244V, A272P, K275R, Q278H, T286TP, A288S, I293IV, K311R, T338TA, K350R, R356K, G359S, T369V, S379C, K390R	B
	48-3226	3226-30521	DQ878133	NRTI	NNRTI	D67N, K70R, L74V, M184V, T215F, K219Q	K103S, Y181C	V35M, K64H, T69N, V118I, K122E, D123N, I135T, V179I, F214L, D218E, L228H, I293V, E297EA, I326V, I329V, F346Y, G359S, V365I, A371V, K388KR, K390R	B
	48-3294	3294-30729	DQ878199	NRTI	NNRTI	M41L, D67N, K70G, V75M, M184V, T215Y, K219Q	K103S	K20R, T39A, E44D, V60I, A98S, V118I, D123E, I135T, I142V, T200I, L210LS, D218E, L228H, A272AP, T286A, I293V, G333GE, R356K, S379SC, K390R	B
	48-4030	4030-30227	DQ878264	NRTI	NNRTI	M41L, D67N, K70R, M184V, L210W, T215Y, K219E	K103S, G190A	P4T, E44D, K102KR, V118I, K122E, Q207K, R211A, D250E, A272P, E291D, I293V, E312EK, Q334I, G335S, M357T, G359S, A371V, K390R	B
	48-4071	4071-30218	DQ878300	NRTI	NNRTI	M41L, V75L, F77L, M184V, L210W, T215Y	K103S, G190A, Y318F	V35M, E40F, K43E, K49KR, V118I, K122E, I135T, Q207E, L228H, Q242H, V245E, K277R, R284K, T286A, I293V, E297K, A376S, S379C, K390R	B
	48-4082	4082-30306	DQ878311	NRTI	NNRTI	M41L, D67N, K70R, V75M, M184V, L210W, T215F, K219Q	K103S, G190A	V60I, K101Q, K122E, I135T, V179VI, D192DN, Q197E, Q207E, L228H, Q242L, K277R, T286A, A288S, E297K, Q334L, A360V, A376T, T386A, K390KR	B
	48-4100	4100-30224	DQ878330	NRTI	NNRTI	M41L, D67N, K70R, L74I, T215F, K219Q	K103S, G190A	V35LM, K43KN, T69N, D123E, S162CW, V179I, T200AV, Q207E, D218E, L228H, A272P, R284K, T286A, E297K, K347Q, K350KR, M357MI, G359S, K366R, A376AT, S379C	B
	48-4168	4168-30408	DQ878402	NRTI	NNRTI	M41L, D67N, L74V, M184V, L210W, T215Y, K219N	K103S, Y181C	K20R, K43Q, E44D, V60I, K64R, V118I, K122E, V179I, H208Y, D218E, A272AP, K277R, E291D, I293V, D324E, R356K, G359S, T369V, I375V	B
	48-4188	4188-30403	DQ878422	NRTI	NNRTI	M41L, D67N, T69DN, K70KR, L74I, V75S, M184MV, T215F, K219Q	K103S, G190A, K238T	V35I, K43Q, I94IL, K122P, I142IL, S162DN, K166KR, D177E, I178F, G196E, I202IV, E203K, Q207D, H208Y, L210F, R211K, D218E, L228H, V245E, A272P, Q278H, I293V, E297R, I329L, Q334E, R356K, M357T, A360V, A376T, K390R, Q394L, E399D	B
	48-4248	4248-30617	DQ878481	NRTI	NNRTI	M41L, D67N, K70R, L74I, M184V, L210W, T215Y, K219Q, N348I	K103S, G190AS, K238T	V35L, T39AE, E44D, K64KR, I94L, K122E, I135T, V189VI, H208Y, R211K, L228H, Q242H, V245E, A272P, I293V, E297K, R356K, M357R, G359S, S379G, K390R	B
	48-4392	4392-30722	DQ878532	NRTI	NNRTI	M41L, D67N, T69D, V75M, M184V, L210W, T215Y, K219R	A98G, K103S, G190A, Y318F	K43Q, E44D, V60I, V118I, D123E, I135V, I142V, S162Y, G196E, T200A, E203D, H208Y, R211K, W212C, L228H, V245Q, I293V, E297EK, Q334E, G359S, K390R, E399D	B
	48-5053	5053-30516	DQ878574	NRTI	NNRTI	M41L, D67N, K70KR, L74I, V75T, M184V, L210W, T215Y, K219E	L100I, K103S	K20R, V35I, T39A, E44D, V118I, K122E, D123E, S162D, D177G, G196E, T200A, E203K, H208Y, R211K, D218E, K223Q, L228H, Q242H, A272P, K277R, L283I, I293V, E297A, Y342F, G359S, A371V, A376S, S379C, K390R	B
	48-5091	5091-30901	DQ878591	NRTI	NNRTI	D67N, T69D, M184V, L210W, T215Y	K101P, K103S	K11KR, K20R, D123E, I142V, T200E, E203K, Q207E, R211K, A272P, T286P, I293V, E297R, I329IV, G333D, G335S, K366R, A371V, A376T, S379SC	B
	48-6162	6162-30903	DQ878738	NRTI	NNRTI	M41L, D67N, T69D, V75M, M184V, L210W, T215Y	K103S, G190A	V35I, K43E, E44A, V60I, E79D, K82R, R83K, V118I, K122E, I135T, K166R, D177DN, V179VI, G196E, E203D, Q207E, H208Y, R211K, A272P, K277R, E297K, D324DE, G335S, M357R, S379C, K390R, Q394T, K395R	B
	48-7110	7110-30930	DQ878963	NRTI	NNRTI	D67N, T69D, K70KR, L74I, V75T, M184V, T215F, K219Q	K101P, K103S	K20R, E28K, V35I, V118I, K122E, I135T, E169D, D177E, I178M, G196E, H208HY, F214L, A272P, P294A, Q334L, M357T, G359S, A371V, A376T, T386A	B
	48-9038	9038-30901	DQ880676	NRTI	NNRTI	D67N, K70R, T215F, K219Q	K103S, G190A	K101Q, K122E, I135IV, S162C, I178M, D192N, T200A, E203ED, Q207E, L228H, V245E	B
	48-9215	9215-30908	DQ880818	NRTI	NNRTI	M41L, D67N, T69D, L74V, L210W, T215Y	K103S, Y181C, G190A	T39A, K101Q, V118I, K122E, I135T, E138M, S162SN, V179I, G196E, T200A, E203V, Q207E	B
	48-9332	9332-30929	DQ880908	NRTI	NNRTI	M41L, D67N, K70R, M184V, L210W, T215CHRY, K219E	K103S, G190A	T39A, V60VI, T69N, D123E, S162D, K166R, D177E, V179I, R211K, V245M	B
	48-9078	9078-30903	DQ880704	NRTI	NNRTI	D67N, K70KR, L74V, M184V, K219E	K103S, G190A	K102Q, V106L, K122E, I135T, K173Q, D177E, R211K, I244IV, V245A	B
	48-9264	9264-30923	DQ880858	NRTI	NNRTI	M41L, D67N, L210W, T215FY	K101P, K103S	K43E, E44EA, V60VI, V118I, K122P, D123E, I135IT, S162SDGN, I178L, V179I, G196GE, Q197K, V245M	B
	48-9113	9113-30918	DQ880731	NRTI	NNRTI	D67N, K70R, M184MV, T215F, K219Q	K103S, G190A	T39A, I94L, K122E, D123S, V179I, T200A, E203K, Q207E, K223Q, V245VM	B
	48-7229	7229-30930	DQ879042	NRTI	NNRTI	D67N, K70R, V75VM, M184V, T215F, K219Q	K101P, K103S	K20R, E28K, K32E, V60I, T69N, K122E, I135T, S162CY, D177E, V179I, D192N, T200E, F214L, D218E, A272P, I293V, E297K, I329L, G333E, R356K, A360V, E399D	B
	48-8003	8003-30501	DQ879048	NRTI	NNRTI	A62V, K65R, D67N, V75I, F77L, Y115F, Q151M, M184V	K103S, G190A, K238KT	A33IV, T58N, T69S, V106VI, K122E, I135T, Q207K, R211A, F214L, K219G, K249Q, K275Q, I293V, E297K, I326V, Q334EK, A355S, R356K, K366R, T369A, A376V, T386AV	B
	48-8096	8096-30901	DQ879093	NRTI	NNRTI	M41L, D67N, L74V, M184V, L210W, T215Y, K219KR	K103S	V35I, K43Q, E44D, V118I, K122E, I135T, I142V, V179I, G196GE, T200TA, E203EK, Q207E, H208Y, R211K, D218DE, K223KPQT, L228H, D324E, R356K, A360V, I375V, E399D	B
Rhee (2006)	CA14314	CA34521		D4T, 3TC, Unknown	EFV, Unknown	D67G, K70R, M184V, T215V, K219E	K101P, K103S	V60VI, S68G, T69N, K102Q, I142IV, D177E, I178L, T200A, I293V, E297K	B
Rios (2007)	CH35	MR_CH35	EF193924	Unknown, D4T, 3TC	Unknown, NVP	M41L, M184V, L210W, T215Y	A98G, K103S, G190A	K49R, V60I, R83K, K122E, E169D, R172RK, T200A, Q207E, L228R, A272P	B
Rosen-Zvi (2008)	61	07p61-6		AZT, DDC, 3TC, D4T, DDI	DLV	M41L, D67N, M184V, T215Y, K219R	K103S	K20R, T27S, E29K, T39A, K43E, E44D, V60I, V108VA, D123E, E138Q, I142V, D177E, I178L, V179I, E203D, Q207E, L210S, L228H, I293V, P294Q, E297K	B
Cardoso (2009)	3023	BRGO3023	FJ638424	NRTI	NNRTI	D67N, K70R, M184V, T215F, K219Q	K103S, Y181C, G190A	K20R, V35M, T69TN, K101Q, V106I, V118I, I135T, K166R, D177E, I202IV, H208HY, R211K, F214L, H221Y	B
	3124	BRGO3124	FJ638456	NRTI	NNRTI	M41L, D67N, K70R, V75M, M184V, L210W, T215Y, K219E	K103S, G190A	E28K, K32E, V60I, K122E, K173Q, R211K, Q222R	B
Kagan (2009)	10	10		NRTI	NNRTI		K101P, K103S	K20R, V35I, V60I, K122E, D177E, I178M, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V317A, M357T, A376T, K390R, A400T	B
	13	13		NRTI	NNRTI		K103S	V35I, R83K, K122E, D123E, A158S, Q174H, I178M, G196E, T200I, R211G, F214L, A272P, K277R, K281R, I293V, E297K, I329V, G333E, Q334H, A360T, A376T, E399D, A400T	B
	2	2		NRTI	NNRTI	M184V, N348I	K101P, K103S	K20R, V21I, V60I, K122Q, I135V, E138A, I178M, V179I, G196E, F214L, A272P, K277R, T286A, A288S, K323R, M357T, A376S, K390R, A400S	B
	4	4		NRTI	NNRTI	K65R, M184V, T215D	K101P, K103S	E6K, V35I, S68G, T69I, K104R, G112A, K122E, I135T, T200I, F214L, K277R, I293V, R358K, A376T, A400T	B
	5	5		NRTI	NNRTI	M41L, M184V, L210W, T215Y	K101P, K103S	T7I, K20R, V35I, K43E, V60I, S68G, K122P, K166R, D177E, I178L, T200A, F214L, V245E, A272P, K277R, I293V, E297R, G333E, Q334H, G335S, R356K, G359S, A371V, A376T, K390R, A400T	B
	7	7		NRTI	NNRTI	M41L, M184V, L210W, T215Y, N348I	K101P, K103S	T39A, D121H, K122E, K166R, V179I, Q207A, R211K, F214L, V276I, K277R, Q278H, T286A, D324E, R356K, M357T, A376T, T386V, E399K, A400V	B
	8	8		NRTI	NNRTI	D67G, T69D, K70R, M184V, T215F, K219Q	K101P, K103S	K11R, V60I, V118I, K122E, D123N, Q174R, N175Y, D177N, V179I, T200E, I202V, F214L, A272P, K277R, I293V, E297K, D324E, R356K, T369V, I375V, A376T, T386A, K390R, A400I	B
Rhee (2009)	CA4340	CA68601	FJ983170	AZT, 3TC, TDF, DDI	NVP		K103S, G190A	P4S, M16V, K122E, I142V, V179VI, T200A, Q207E, R211K, F214L, I293V, P294A	B
	CA25695	CA59667	FJ983541	D4T, 3TC	EFV, NVP	K70KR, M184V	K103S, G190A	V35VI, R83K, V179VI, T200AE, E204ED, R211K, F214L, Y271YH, A272P, I293V, E297AT, A327V	B
Dau (2010)	06693A	06693A	GU581768	NRTI	NNRTI	M41L, M184V, T215F, N348I	K103S, G190A	I135V, I142T, S162A, K173Q, F214L, A272P, I293V, E297A, G333E, Q334Y, G359S, A376S, K390R, A400S	B
	06724A	06724A	GU581774	NRTI	NNRTI	M41L, D67N, V75M, M184V, L210W, T215Y, K219N, N348I	K103S, V108I, G190A	K20R, I31V, V35L, T39A, K43E, E44A, E53D, V60I, R83K, V118I, K122P, D123E, I142IT, I178IM, H208FY, R211K, D218E, L228H, A272P, L283I, I293V, M357R, A371V, I375V, K388N, K390KR	B
	07236A	07236A	GU581827	NRTI	NNRTI	M41L, D67N, V75M, M184V, L210W, T215Y, K219N, N348I	K103S, V108I, G190A	K20R, I31V, V35L, T39A, K43E, E44A, E53D, V60I, R83K, V118I, K122P, D123E, I178IM, H208Y, R211K, D218E, L228HN, A272P, L283I, I293V, M357R, A371V, I375V, K388KNT	B
	07713A	07713A	GU581862	NRTI	NNRTI	M41L, M184V, T215C	K103S	V35T, K122E, D177E, I178M, T200I, R211K, F214L, A272P, T286A, I293V, E297K, K311R, D324E, A371V	B
	09676A	09676A	GU581976	NRTI	NNRTI	D67N, T69DE, K70R, Q151M, M184V, T215F, K219Q, N348NI	K103S, G190A	K30KR, V106I, G112A, K122E, D123DN, M164L, T200E, F214L, I293V, I341IF, M357T, E370ED, A376T, I382IL, T386A, K390R, T397V	B
Bunupuradah (2011)	079-007-010	079-007-010		D4T, 3TC	NVP	M184V	K103S	V35T, V118I, K122E, I135T, S162C, R211S, F214L, V245E	B
Jones (2012)	135448	135448	JN669543	NRTI	NNRTI	D67N, L74I, M184V, T215F, K219Q	K101P, K103S	K20R, K122E, I202V, V245K, A272P, Q278E, V292I, E298A, R356K, G359S, A376V, T386A, K390R	B
	140306	140306	JN669588	NRTI	NNRTI	M41L, D67N, K70KR, M184V, L210W, T215Y, K219D	K103S	V35T, E44D, K102Q, V118I, Q174R, D177DGNS, G196E, E203D, H208Y, R211K, L228H, A272P, V276I, L283I, I293V, E297R, S322T, K350R, R356K, A360T, K366R, T369V, A376V, S379C, T386A, K390R	B
	145136	145136	JN669653	NRTI	NNRTI	M184V, K219KR	K103S, G190A	K20R, E53ED, K122E, I135T, I142IT, K166R, G196E, R211RK, F214L, V245I, A272P, K277KR, I293V, E297Q, R307RW, Q334L, G335GC, E344ED, K347KR, A376S, S379C, V381I, T386V, K390R	B
	146046	146046	JN669668	NRTI	NNRTI	M41L, D67N, V75M, L210W, T215Y, K219N	K103S, Y188YN, G190S	K20R, W24WR, V35M, T39A, K43E, E44A, V60I, S68SG, W88CG, I94L, V118I, K122E, I135L, D192DA, H208Y, R211K, L228H, V245E, A272P, K277R, T286A, I293V, E297KR, M357Q, R358K, G359S, T386TI, K390R, Q394QL, E399D	B
	146486	146486	JN669677	NRTI	NNRTI		K103S, K238T	V35VI, R78RK, K122E, D123E, I135T, I142T, D177DE, I178L, V179I, A272P, E297R, A376T, T377Q, T386I, K390R, Q394L	B
	151017	151017	JN669756	NRTI	NNRTI	M41L, D67N, K70R, L74LI, L210W, T215Y, K219E, N348I	K103S, G190A	W24WG, V35T, E44D, V60I, I94IL, K102KE, V118I, K122E, D123E, I142IV, R172K, N175NK, R211K, L228H, A272P, K277R, E297K, R356RK, K366R, Q367QR, A376T, S379SC, K390R, E399AD, A400PT	B
	156156	156156	JN669852	NRTI	NNRTI	M184V, T215F	K103S, G190A, P225H	K20R, V35K, V60I, I135V, I142V, K173N, I202V, Q207E, R211K, A272P, K277R, I293V, E297K, Q334L, M357T, A360T, E399D	B
	161866	161866	JN670018	NRTI	NNRTI	M41L, M184MV, T215Y	K103S, G190GA	K20KR, V35T, V60I, S68SG, K102KR, D113DG, A272P, K281R, I293V, E297K, V317A, Q334D, F346FY, I375V, A376S, K390R, E399D	B
	165635	165635	JN670109	NRTI	NNRTI	L74V, T215Y	K101P, K103S, G190A	E28K, K32E, V35I, V60I, S68G, K122E, D123DE, I135T, I142T, V179I, T200I, A272P, Q278H, L283I, E297T, Q334R, R356K, T377R, T386I, K390R, Q394L	B
	173615	173615	JN670336	NRTI	NNRTI	M184V	K103S, G190A, K238T	V35T, D123E, A272P, K281R, E297R, A376S, S379SC, V381VI, K388KR, K395R, E399D	B
	177184	177184	JN670429	NRTI	NNRTI	M184V, N348I	K103S, G190A	V35T, T39M, V60I, D123E, I135T, I178IM, R211K, A272P, K277R, K281R, E297R, D324E, I329L, A376CST, K390R, E399D	B
	179865	179865	JN670529	NRTI	NNRTI	M41L, D67N, T69D, T215Y	A98G, K103S	E6D, V35I, E44D, N54I, W88C, V118I, D123E, I178IM, V179I, V189I, T200A, E203D, Q207E, H208Y, L210Y, A272P, K281KR, T286A, E297K, Q334L, M357T, R358K, A376T, V381I, T386I	B
	180112	180112	JN670536	NRTI	NNRTI	D67N, K70R, M184V, T215FY, K219E, N348I	K103S, G190A	V35I, V90I, I94L, K122E, I135L, Q174K, P176T, D177E, I202V, Q207D, R211K, V245E, K277R, I293V, P294T, E297A, I326T, I329V, Q334L, R358K, A371V, V381I, K385R, T386V, K390R	B
	180359	180359	JN670545	NRTI	NNRTI	M41L, D67N, T69D, V75M, L210W, T215Y, K219KR	K103S, Y181YC, G190A	E6K, V21I, V35VA, T39A, K43KAET, E44D, V60I, K101KR, K122E, E169D, V189VI, G196E, R211RK, K223KQ, L228LR, V245T, A272P, K281R, T286A, I293V, E297R, G333E, M357T, Q394L, E399D	B
	181413	181413	JN670576	NRTI	NNRTI	M41L, L74LI, M184V, L210LW, T215Y	K103S, G190A	T7TA, V35T, K102R, K122V, D123E, I135V, R211K, D237E, A272P, K277R, T286A, E297K, M357T, K366R, A376S, S379C, Q394L, E399D	B
	187321	187321	JN670730	NRTI	NNRTI	M41L, D67N, L210W, T215Y	K103S, G190A	K20R, E44D, V60I, V118I, K122E, I135T, E169D, V179I, T200A, I202V, V245KM, K277R, A288S, I293V, E297V, R358K, A371V, A376AS, T386I, K390R	B
	189477	189477	JN670773	NRTI	NNRTI	M184V	K103S, G190A, Y318YF	E6K, V35IT, T39TA, K43KN, K49KR, R83RK, K102Q, K122E, T200TA, Q207DE, F214L, A272P, K281R, E291D, E297K, D324DE, F346Y, M357T	B
	189584	189584	JN670777	NRTI	NNRTI	M184V, T215Y	K103S, G190A	V35T, V60I, V90I, I135L, S162SHPY, D177E, T200A, E203D, R211RK, P243T, A272P, K281R, E297K, D324E, L325I, M357T, V365I, A376S, T386I, E399D	B
	191261	191261	JN670818	NRTI	NNRTI	D67N, K70R, M184V, K219E	K103S, G190A	V60I, T69N, K102KR, K122E, V179I, G196E, Q197K, A272P, T286A, A288T, E297K, R356K, A360T, A376CS, K390R	B
	195201	195201	JN670970	NRTI	NNRTI	M41L, D67G, T69D, L210W, T215Y, K219R	K103S, Y181V	K20R, V35M, T39A, K43Q, E44D, S68T, V90I, V106I, V111I, V118I, K122KE, E138G, I159IL, S162SG, K166RS, I178IL, G196E, T200TA, E203V, Q207D, H208Y, R211K, W212M, D218E, K223PQ, L228H, A272P, K277R, T286A, V292I, I293V, E297R, D324E, I326V, Q334L, G335S, M357T, T386IV, K390R	B
	196854	196854	JN671041	NRTI	NNRTI	M184V	K101P, K103S	E28K, K49R, K122Q, I135T, K166R, E169D, D177E, I178L, I202V, R211K, V245M, Y271YF, A272P, V276I, K277KR, T286A, I293V, P294S, E297R, Q334E, P345Q, K366R, A376S, T386I, K390R	B
	201748	201748	JN671234	NRTI	NNRTI	D67N, K70G, M184V, T215F, K219Q	K103S, G190A	P4T, E6K, K122E, V179I, I195L, I202V, R211K, V245M, A288S, I293V, P294T, E297A, D324E, A327V, Q334P, M357T, V365I, A371V, I375V, A376T, T386A, K390R, E399D	B
	202044	202044	JN671251	NRTI	NNRTI	M184V, N348I	K103S, G190A	V35T, V60I, I135V, I142V, Q197P, R211K, D237N, A272P, E297K, R358RK, G359S, K366R, E399D	B
	202391	202391	JN671271	NRTI	NNRTI		K101P, K103S	K49R, V90I, K122Q, K166R, E169D, D177E, I178L, I202V, R211K, V245M, A272P, V276I, K277KR, T286A, I293V, P294S, E297R, Q334E, Y342F, K366R, A376S, T386I, K390R	B
	203414	203414	JN671310	NRTI	NNRTI	M41L, D67N, T69D, K70R, L74LI, M184V, T215F, K219Q, N348I	K103S, G190A	P4ST, K20R, V35T, T39TA, V60I, I94L, D177E, F214L, L228H, V245E, A272P, I293V, E297A, Q334E, F346H, M357T, T369A, E370G, S379G, K385R	B
	206604	206604	JN671402	NRTI	NNRTI	M41L, D67N, K70R, T215F, K219Q	K101E, K103S, G190A	E28K, K32E, V35I, T39A, V60I, D177N, T200A, R211K, L228F, V245K, T286A, E297A, D324E, I326V, R356K, G359S, A360T, K390R, E399D	B

Reverse Transcriptase Inhibitors

Database

Resources

Team