<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation K103N
Rx >= 1 NRTI
(but no NNRTI)
IncludeMixtures No
References 15
Patients 21
Isolates 22
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Baxter (2000)GART-G140GART-140 NRTI, AZT, 3TCNoneM41L, M184V, L210W, T215YK103NV35T, K49R, A98AS, K102R, K122E, E169D, D177E, I178M, Q207E, R211K, A272PB
Eshleman (2001)A067AF357668AF357668AZT, DDINoneM41L, T215YK103NK20R, K102R, K122E, Q278H, T286AB
Gonzales (2001)CA2103CA7758AY030810AZT, DDI, DDC, D4T, 3TCNoneM41L, A62V, D67N, L74I, M184V, L210W, T215F, K219QK103NV35L, K64KR, K122E, K173E, I178L, V179VI, D218E, L228HB
 CA3886CA9078AY030891AZT, 3TCNoneM184VK103NI135V, S162C, I178L, R211K, L234LH, P243PHB
Naugler (2002)WES-11HIV11ESAF422733AZT, DDINoneM41L, L210W, T215SK103NV35L, E42V, V60G, A62P, L100V, V106I, I202V, R211KB
Shafer (2003)A384_31043104bEF548272D4T, DDINone K103NT39S, R83K, K122E, S162C, S163T, Q207E, E248ED, A272P, T286A, I293IL, E297TB
 A384_24362436b AZT, 3TCNone K103NS48T, E79D, I178L, R211K, V245KB
 A384_17441744bEF548751AZT, 3TCNone K101E, K103ND123E, I142V, T200E, Q207G, V245KB
Dumans (2004)260260AY390162AZT, DDINoneM41L, L210W, T215SK103NV118I, D121Y, K122E, D123E, I135T, S162C, D177E, G196E, Q207H, R211KB
Gulick (2004)RG444RG444w90 ABC, AZT, 3TC, DDINone K103NR83K, K166R, I178L, R211KB
 RG469RG469w100 ABC, AZT, 3TCNoneY115F, M184VK103NT39S, V90VI, K101R, K122E, D123N, I142V, S162A, E169D, Q174K, G196E, Q207E, R211K, L228R, V245QB
Montes (2004)MB_patCAS00_CASE717AJ577859DDC, AZT, 3TC, D4T, DDI, ABCNoneM41L, D67N, T69D, L74V, L210W, T215YK103NE6D, T39K, K43E, E44D, V60I, V118I, K122P, D123E, I135T, S162N, K173T, D177E, G196D, E203K, Q207E, H208Y, R211K, K223QB
Gallant (2005)JEG33JEG33_w12DQ199606ABC, TDF, 3TCNone K103NQ23Q*, T69A, R83K, D121C, K122E, S162C, D177E, A272P, K277RB
Dumans (2009)RENA686RENA686FJ405043AZT, 3TCNoneD67G, K70R, M184V, T215F, K219EK103NK20R, V35M, S68G, R83K, D123E, V245K, A272P, K281R, E297R, Q334DB
 117PR117PRFJ405058AZT, 3TC, D4T, DDINone K103NK20R, K122E, Q174H, D177N, Q197E, I202V, D256AB
Rhee (2009)CA9699CA23740FJ983316AZT, 3TCNoneD67N, M184V, K219QK103NK11KR, K20R, V35I, V60I, I135T, S162A, K166R, R172RK, Q207E, R211K, K277R, I293VB
 CA22110CA51131FJ983497AZT, 3TCNoneM41L, M184V, T215YK103NK20R, K122E, T200A, R211KB
Melikian (2012) CA95213GQ213522AZT, 3TC, TDF, DDINoneM41L, L210W, T215YK103NK20R, V60VI, V118VI, K122E, D123DG, V179VI, T200A, R211K, I270IFB
Mollan (2012)MK204MK204w36 ABC, 3TCNoneL74LI, M184V, T215SK103NT39A, K122E, I135T, I142T, S162C, R172RK, T200A, Q207E, P294TB
Kim (2013)Tx14281KC1208743TC, DDINone K103NK101Q, D121H, K122E, I135R, T200I, V245A, L246I, I293V, E297G, E312Q, S322AB
 Tx34370KC1209083TC, DDINone K103NI135V, S162SN, E169D, V179A, G196E, I202V, F214L, V245Q, S251C, I293V, K311R, P313Q, V317AB
Lam (2016)20420032042003KR867840ABC, D4T, 3TCNone K103NK64R, I135T, T200A, R211K, V245T, K277R, I293V, E297K, A304E, I329L, G333EB