<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype B
Gene RT
Mutation K101R
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 25
Patients 80
Isolates 88
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Gonzales (2001)CA2314CA8403AY030859DDI, AZT, D4T, 3TCNVPM41L, D67N, L74V, M184V, L210W, T215Y, K219NK103N, V108I, Y181C, F227LK20R, K43N, K101R, V118I, I135T, I202IV, E203K, R211K, K223EB
 CA4572CA11198AY031369D4T, 3TC, AZTNVPD67N, K70R, M184V, T215F, K219QG190AV35IM, K101R, K122E, D123N, T139R, S162C, T200A, E204D, Q207G, K223Q, V245QB
 CA4753CA11628AY0314143TC, AZT, ADV, D4T, DDIDLV, EFV  K101R, D121Y, K122E, K166KR, P176PT, K277R, Q278H, I293VB
 CA5039CA12313AY031610AZT, DDI, 3TC, ABCEFVM41L, D67N, T69D, V75M, L210W, T215YL100I, K103NK20R, T39AE, E40F, K43E, V60I, K101R, V118I, K122E, I135T, G196E, E203K, Q207E, R211K, N265ISB
 CA5974CA14743AY032221D4T, 3TC, UnknownNVP, Unknown  S48T, K82KR, K101R, K102KM, K122E, D123N, I142T, K166R, Q207E, F214L, K277RB
 CA6455CA15972AY0324063TC, D4T, ABC, DDIEFVL74LV, M184VK103N, L234LIK101R, K102Q, I135V, I142V, S162A, Q174H, R211K, H221HY, V245EB
Gonzales (2003)CA1860CA16956AF514127AZT, 3TC, D4T, DDIEFVM41L, D67N, T69D, K70R, L74IV, M184I, T215F, K219QA98G, G190EK20R, V35E, T39A, V60I, K101R, K103R, V118I, K122E, I135K, F214L, L228H, I293V, E297K, A360AP, T386I, K390R, A400T, V435A, A437V, V466I, V467I, Q509Y, K527NS, A554TB
 CA4753CA12502AF5142093TC, AZT, ADV, D4T, DDIDLV, EFV K103NK101R, D121Y, K122E, D177E, K277R, Q278HB
Gomez-Carrillo (2004)9837198371AY365576NRTINNRTIM184V, T215Y, N348IY181CK20R, K49R, K101R, I135T, T286TA, I293V, Q334A, I341F, R356K, R358K, E370G, T386I, E399ED, A400ATB
 104182104182AY365695NRTINNRTIL74V, Y115FK103N, Y181C, G190AM16MI, K49R, K101R, D123E, D177E, I178V, E203K, R206RK, R211K, L228R, A272P, K277R, T286A, E297A, I326IV, A360T, A376T, Q394L, E399DB
 106543106543AY365752NRTINNRTIM41L, L74V, T215FK103N, Y181CK101R, K122E, I135T, I142V, S162C, K223KQ, L228R, I293V, A360T, K390RB
 118747118747AY365954NRTINNRTIM41L, D67H, L74V, V75M, L210W, T215Y, K219N, N348NIG190EK20R, T39A, E44D, K66N, T69N, K101R, K103R, V118I, K122E, E138A, I142V, S162C, T200A, L228H, T286A, I293V, E297R, I329IV, Q334E, I341IF, G359S, K395KRB
Gulick (2004)RG226RG226w20 ABC, AZT, 3TCEFV  K101R, S134G, S162C, G196E, T200IL, F214L, V245TB
 RG260RG260w41 ABC, AZT, 3TC, DDIEFV  S48E, K101R, D123E, T165TI, D177E, R211K, K219K*B
 RG480RG480w92 ABC, AZT, 3TCEFV  A98S, K101R, K122E, I135V, S162C, D177E, G196E, V245EB
 RG62RG62w25 AZT, 3TC, DDIEFV  I37X, K101R, S162C, Q197EB
Montes (2004)MB_patFER99_FER709AJ577888AZT, D4T, DDIEFVM41L, T69D K20R, K101R, D123E, S162C, D177EB
Garcia-Bujalance (2005)GBS_07GBS_07AY872342AZT, DDI, D4T, 3TCNVPM184V, T215FK103S, G190AK101R, L120I, D121Y, K122E, I135T, F214LB
Mo (2005)90199019_d349 NRTINVPM184MVY181YC, G190GAV60I, T69TN, K101R, K122KE, I135T, T200TI, V245M, A272P, A288ASB
Non-B Workgroup (2005)TH_581TH_581 AZT, 3TCNVP K103NK101R, T107S, K122E, D123N, S162C, K173N, Q174K, D177E, I178M, R211KB
Podzamczer (2005)DP_108DP_108m3 TDF, DDIEFVK219NG190EV60I, K101R, D121H, K122E, Q174K, D177E, R211KB
Rhee (2005)CA1860CA37912AY801105AZT, 3TC, D4T, DDI, ABC, TDFEFVM41L, D67N, T69D, K70R, L74I, M184I, T215F, K219QA98G, G190EK20R, V35E, T39A, V60I, K101R, K103R, V118I, K122E, I135K, F214L, L228H, V245A, I293V, E297KB
 CA2362CA8549AY801179D4T, AZT, 3TCNVPM41L, D67N, T69D, M184V, L210W, T215YK103NK13KR, K20R, K43Q, V60I, K101R, I135V, S162C, G196E, Q207E, R211KB
  CA9041AY801180D4T, AZT, 3TC, UnknownNVP, UnknownM41L, D67N, T69D, M184V, L210W, T215YK103NK13KR, K20R, K43Q, V60I, K101R, I135V, S162C, G196E, Q207E, R211KB
 SWC-46034603-2140 AZT, DDC, 3TCEFVM41L, M184V, L210W, T215Y A98S, K101R, K122X, I135T, I142X, A272PB
 ASRU020ASRU020 D4T, DDI, AZT, 3TCNVPM184V, T215YK103NI31L, K101R, S163T, D177E, Q207EB
 CA6462CA21068AY801658DDC, AZT, 3TC, D4T, ABC, DDINVPD67N, K70R, L74V, M184V, K219Q, N348IK103N, Y181CT69X, K101R, K102Q, K122E, D123N, I135L, I142T, K166R, V179VI, Q207H, R211K, L228LH, K238KE, A272PT, V276VI, Q278H, T286A, P345A, G359S, K366R, A371V, A376V, K390R, A400T, T403S, D460N, S468T, T470N, H483Y, L491S, K512R, S519N, V531I, K550R, A554T, K558RB
 CA6864CA16934AY801718Unknown, D4T, 3TC, AZTUnknown, NVP, EFV G190SR83K, V90I, K101R, I135T, S162Y, V179VG, D237E, V245E, I293V, L295LR, A299AGB
 CA7880CA19923AY802709D4T, 3TCEFVD67N, T215V, K219Q V35I, V60I, K64KR, K101R, V118I, K122E, I135T, Q174N, Q207E, R211K, F214L, I293VB
 CA7930CA19997AY801849AZT, 3TCEFV  K101R, K102Q, S162Y, G196R, T200A, E203D, Q207E, K277R, I293VB
 CA7968CA20046AY801871AZT, 3TC, D4T, DDC, ABC, UnknownNVP, EFV, UnknownM41L, L74V, T215YK103N, Y181C, G190AK101R, I135V, V179VI, R211RG, Y271YHB
 CA8049CA48096AY801929AZT, 3TC, D4T, DDI, TDFEFVD67N, K70R, T215I, K219EG190EV35L, S48SL, R83K, K101R, K103R, D177E, I178M, D192DG, G196E, T200A, E204N, L205LP, R211K, L228R, V245E, A272P, T286A, E297KB
 CA16156CA38451AY802438AZT, DDC, D4T, 3TC, ABCNVPM41L, D67N, K70R, L74I, M184V, K219QV108VI, V179VD, Y181CK32N, V35I, T69N, K101R, K103KR, I135K, G196E, L228H, V245I, K249R, S251H, K277R, A288T, V292I, I293V, E297KB
 CA17616CA41473AY802533TDF, 3TCNVPK65KR, M184MVV108VI, Y181C, Y188YHK20R, V35L, K101R, K122E, I132IL, S162C, K166KR, E203EK, Q207E, R211K, V245E, A272P, E291D, V292I, I293VB
Baxter (2006)12-40084008-30129DQ880392NRTINNRTIA62AV, K65KR, K70KR, V75VI, F77FL, F116FY, Q151LM, M184MV, T215TFISY188LS68SG, T69TN, K101R, K122E, E138A, T139TA, I142T, S162SC, T165TI, I178IM, V179VI, I202IV, Q207D, R211KB
 12-13091309-30505DQ879399NRTINNRTID67N, K70R, M184V, K219QK103NV60VI, K101R, T200A, E203K, R211KB
 12-10491049-30304DQ879179NRTINNRTIM41L, T69S_SS, V75M, M184V, T215YA98G, K103N, Y181C, G190AK64KR, K101R, K122E, H208Y, R211RKT, L228H, V245EKB
 12-19211921-30529DQ879873NRTINNRTIM41L, L74V, T215YK103N, Y181C, G190AK101R, K122E, I135T, K166RB
 12-21612161-30708DQ880066NRTINNRTIM41L, D67N, T69D, K70R, L74V, T215F, K219QK103N, Y181CV60I, K101R, K122E, I135T, I167V, G196E, D218EB
 12-11881188-30421DQ879294NRTINNRTIM184MV K101R, I135T, K166R, I178M, E194K, G196E, T200A, Q207EB
 48-11371137-30729DQ880569NRTINNRTIM41L, L74V, M184MV, L210W, T215YA98G, K103N, V179F, Y181C, G190GAE44D, D86DN, K101R, K122E, I135V, E194EQ, G196E, H208HY, D218DE, L228LRB
 48-30323032-30227DQ877943NRTINNRTID67N, K70R, T215F, K219EK103N, V108I, Y181C, G190AT69N, V90I, K101R, L109I, K122V, D123N, I135V, I142V, D177E, I178L, D218E, L228R, V245T, Q278E, L283I, I293V, E297A, R307RK, K350R, A355T, R356K, S379SC, K390RB
 48-71367136-30721DQ878974NRTINNRTIM41L, D67G, L74V, M184V, L210W, T215Y, K219NA98G, K103N, V179F, Y181CE6K, K11KR, K20R, K32KT, T39K, E40X, K43E, E44ED, S68G, K101R, V118I, K122E, Q197E, T200A, E203K, Q207D, H208Y, R211K, K223E, L228H, T286A, T296S, K311R, D324E, I326V, I329V, M357T, R358KB
 48-93289328-30930DQ880905NRTINNRTIM41L, D67DN, L74I, V75T, L210W, T215Y, K219QV108I, Y181CT39TA, E44D, A98S, K101R, K104N, V118I, K122E, S162D, K166R, V179VI, D192DN, T200A, E203K, Q207E, R211K, D218E, L228HB
 48-91279127-30918DQ880745NRTINNRTI Y181CA98S, K101R, I135T, R211K, F214L, L228R, V245EB
Eyer-Silva (2007)BRSQ2504BRSQ25EF042636AZT, 3TCNVP  K101R, D121Y, K122E, I135T, D177EB
Rios (2007)CH49MR_CH49.1EF193941Unknown, AZT, 3TC, D4T, DDIUnknown, NVPD67N, K70R, L210W, T215Y, K219EY181C, G190AK20R, M41I, E42G, E44G, G45R, V60I, K101R, V118I, I135T, Q207K, H208Y, R211K, L228H, V245Q, A272PB
Villena (2007)3670836708-2EF154392D4T, 3TC, DDI, ABCEFVA62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184MVK103N, Y181C, G190AT39A, S68G, T69A, W71W*, K101R, D123E, I135T, I167V, D177E, I202V, R211KB
  MDRc3 D4T, 3TC, DDI, ABCEFVA62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AK20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512TB
  MDRc7 D4T, 3TC, DDI, ABCEFVA62V, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AT39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, I202V, R211K, I293V, P294T, E297K, K331R, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T, L517I, S519N, I522VB
  MDRc3 D4T, 3TC, DDI, ABCEFVA62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AK20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512TB
  MDRc7 D4T, 3TC, DDI, ABCEFVA62V, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AT39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, I202V, R211K, I293V, P294T, E297K, K331R, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T, L517I, S519N, I522VB
  MDRc3 D4T, 3TC, DDI, ABCEFVA62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AK20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512TB
  MDRc7 D4T, 3TC, DDI, ABCEFVA62V, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AT39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, I202V, R211K, I293V, P294T, E297K, K331R, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T, L517I, S519N, I522VB
  MDRc3 D4T, 3TC, DDI, ABCEFVA62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AK20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512TB
  MDRc7 D4T, 3TC, DDI, ABCEFVA62V, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AT39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, I202V, R211K, I293V, P294T, E297K, K331R, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T, L517I, S519N, I522VB
  MDRc3 D4T, 3TC, DDI, ABCEFVA62V, K70G, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AK20R, T39A, S68G, T69A, K101R, D123E, I135T, I167V, D177E, I202V, R211K, I293V, P294T, E297K, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512TB
  MDRc7 D4T, 3TC, DDI, ABCEFVA62V, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AT39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, I202V, R211K, I293V, P294T, E297K, K331R, M357T, I375V, T386I, V435I, E449D, D460N, L491S, K512T, L517I, S519N, I522VB
  36708-3EF154395D4T, 3TC, DDI, ABCEFVA62V, V75I, F77L, Y115F, F116Y, Q151M, M184VK103N, Y181C, G190AK20R, T39A, S68G, T69X, K70X, K101R, D123E, I135T, S163I, I167V, D177E, E194E*, T200A, I202V, R211KB
Riddler (2008)61647362263BaHM056597D4T, 3TCEFV  E6D, V8I, S48T, V60I, A98S, K101R, K122E, I135T, K166R, G196E, T200A, Q207E, V245Q, I257IV, A272P, I293V, D324DE, K350R, M357T, A360T, K366R, T377R, A400T, T403I, E404D, V435A, T450S, R461K, S468N, K476Q, I482V, H483Y, G490E, A502V, K512Q, E514D, E516A, A554SB
  362263BbHM056598D4T, 3TCEFV  E6ED, V8VI, S48T, V60I, A98S, K101R, K122E, I135T, K166R, G196E, T200A, Q207E, V245Q, V254VI, A272P, I293V, D324DE, K350R, M357MT, A360T, K366R, T377R, A400T, T403I, E404D, V435A, T450TS, R461K, S468N, K476Q, I482V, H483Y, G490E, A502V, K512Q, E514D, E516A, A554SB
Rosen-Zvi (2008)600p6-1 DDC, 3TC, D4T, ABC, DDINVP, EFVV75A, F77L, Q151M, K219EK103N, Y181C, G190A, P225HV35L, T69N, K73M, K101R, K122E, I135IV, K173T, T200E, E203K, R211K, V245E, K277R, I293V, E297QB
  00p6-3 DDC, 3TC, D4T, ABC, DDINVP, EFVV75A, F77L, F116Y, Q151M, M184VK103NP4PS, V35L, T69N, K73M, K101R, K122E, I135V, K173T, T200E, R211K, V245E, K277R, I293V, E297Q, D320DYB
Luo (2009)sz.82505HBsz.825FJ375050NRTINNRTIK65RK103N, P225HK101R, I135V, S162C, T200A, R211K, V245E, Q278E, I293V, Q334LB
Dau (2010)05891A05891AGU581690NRTINNRTIM41L, D67N, K70R, L74V, T215F, K219QK103N, Y181C, G190A, K238NK20R, V60I, K101R, K102Q, K122E, D123N, I135V, D218E, I293V, E297R, I329V, A371V, I375VB
 06458A06458AGU581746NRTINNRTID67G, K70R, L74V, M184V, K219QK103N, Y181C, K238TS68G, K101R, Q174R, Q207E, R211K, D218E, T286TA, E312A, Q334L, M357KR, R358G, V365I, K390R, E399GB
 06723B06723BGU581773NRTINNRTID67G, K70R, L74IV, M184V, K219QK103N, Y181C, K238TS68G, K101R, Q174R, Q207E, R211K, F214FL, D218E, T286TA, I293IV, E312A, Q334L, M357KR, R358G, V365I, T369TA, K390R, E399GB
 06725B06725BGU581775NRTINNRTIT215L K101R, I135L, S162C, Q207E, V245M, A272P, T296S, P345PT, A360T, T386TIB
 07057A07057AGU581815NRTINNRTID67G, K70GR, L74IV, Y115YF, M184V, K219QK103N, Y181C, K238TS68G, K101R, Q174R, Q207E, R211K, F214FL, D218E, T286TA, I293IV, E312A, Q334L, M357KR, R358G, V365I, K390R, E399GB
 08177A08177AGU581899NRTINNRTIA62AV, K65RK103N, Y181CR83K, K101R, H221Y, V245E, A272P, E291D, D324E, F346Y, G359S, T386M, K390R, E399DB
 08457A08457AGU581914NRTINNRTIM41L, D67K, K70R, L74V, T215F, K219QK103N, Y181C, G190A, K238NK20R, V35VL, K43KN, V60I, K101R, K102Q, K122E, D123N, I135V, D218E, L228H, D237DN, V245VE, I293V, E297R, I329V, A371V, I375IVB
Aulicino (2011)ARM522BCEARM522BCEFJ525832NRTINNRTIM41L, D67N, T69D, M184V, L210W, T215YK103N, V179F, Y181C, G190AS3C, K32E, V35M, K43E, E44A, K101R, L109X, V111I, K122E, I135V, T139K, I167V, T200A, E203D, H208Y, R211TB
Liu (2011)HNDR2351HNDR2351HQ639703AZT, DDINVP K103NK101R, K122E, I135V, S162C, K173KE, T200TA, I202VB
Ngo-Giang-Huong (2011)PHPT4078PHPT4078PR-RTHQ996529TDF, FTCNVPK65R, Y115F, M184VY181CI31L, K101R, V106I, K122E, I135IV, S162C, P170S, T200AV, Q278E, I293V, Q334LB
El Annaz (2012)322322.RTJN185276AZT, 3TCEFVM184VP236LK20R, T39A, R83K, K101R, K103E, K122P, I135K, E169D, T200A, R211KB
 1347113471.RTJN185311AZT, 3TCEFVM184I K101R, K122E, I135T, S162C, Q207E, R211K, V245QB
 1457514575.RTJN185316NRTINNRTI K103N, V179DK101R, V118I, K122I, I135T, E169D, Q174N, D177E, T200TA, F214LB
Fourati (2012)1008057510080575JQ395830NRTINNRTI  E29K, V35I, E36K, M41I, E42K, K49R, D76N, R83K, K101R, V111M, D123E, I135T, E169D, D186N, E204K, Q207EB
 94508989450898JQ395874NRTINNRTI  V35I, R83K, K101R, D123E, P176PS, D177DE, T200A, Q207E, R211KB
 1027047710270477JQ395772NRTINNRTI  K101R, D121DH, D123E, A158AS, S162NY, P176PS, T200A, Q207E, R211KB
Jones (2012)149331149331JN669732NRTINNRTIY115F, M184V, T215Y P9S, K101R, P119PS, T131TS, D177E, I178M, R211K, L228R, V245M, A272P, K277KR, I293IV, P294PT, E297EA, K311R, D324E, I326V, G359S, A371V, A376S, T386IB
 155992155992JN669849NRTINNRTIM41L, D67N, T69D, L74V, L210W, T215Y, K219NK103N, V179F, Y181CE6D, E40F, K43E, K101R, K102Q, V118I, D121H, K122E, Q174R, T200A, I202V, E203K, Q207E, H208Y, R211RK, K223T, Q278H, I293V, D324E, Q334C, R356K, G359S, T369V, I382L, K390RB
 157710157710JN669897NRTINNRTID67DN, L74V, M184V, T215Y, N348IG190AS48T, R83K, K101R, I135T, S162Y, G196K, R211E, V245E, D250E, A272P, K277R, I293V, P294T, E297A, I329L, R358K, E370EGKR, K390R, E399DB
 159806159806JN669963NRTINNRTIT215DK103N, Y181CK20R, V60I, K101R, D121Y, K122E, I135T, T200A, F214FL, A272P, I293V, E297R, L301I, A304E, A360T, K366KRB
 161980161980JN670023NRTINNRTIL74LV I37IF, K101R, Q145QE, S162Y, W229WG, A272P, K277R, E297K, G333E, Q334Y, K350R, R356K, M357MT, G359GSB
 167152167152JN670146NRTINNRTIL74V, Y115F, M184V, T215VY181CI50IM, T69TA, F77IT, E79D, R83K, F87FS, V90I, K101R, L109LR, S162Y, V179I, R211K, F214L, E224D, L228R, V245E, I293V, E297V, I329V, Q334L, R358K, G359S, A371I, K390RB
 175141175141JN670352NRTINNRTIM41L, A62V, V75I, M184V, T215FK103NI31L, K101R, D177E, I178IM, Q197QE, T200TA, R211K, V245T, D250E, A272P, K277R, E297A, Q334E, M357T, R358K, E370A, A376T, K390KRB
 183146183146JN670640NRTINNRTIL74LV, Y115YF, M184MVK103KN, P225PHK20R, K101R, D177E, I178L, E204N, F214FL, V245M, A272P, V276I, T286A, E297T, I326V, I329L, F346L, M357V, A360T, T369TI, A376S, T386I, K390RB
 183901183901JN670663NRTINNRTIY115F, M184V, T215YL100I, K103NK43KR, K101R, D177E, I178M, V189I, R211K, L228R, V245M, A272P, K277R, I293V, E297A, K311R, D324E, I326V, G359S, A371V, A376S, T386IB
 193454193454JN670900NRTINNRTIA62V, K65R, K70R, V75I, F116Y, Q151M, K219EK103N, Y181I, G190AK11KR, K20R, S68K, A98AS, K101R, V118I, K122P, I135T, I178IM, V179VL, Q207K, F214L, Y232H, V245E, S251I, K277R, P294Q, E297A, K311KR, K366R, T386IB
 201100201100JN671213NRTINNRTID67N, K70R, L74V, F77FL, Y115F, Q151M, M184V, K219QG190EV90I, K101R, V111I, D123E, I135V, S162A, M164L, D177E, F214L, A272P, L283I, R284K, I293V, E297R, A304T, G359S, K390R, A400ATB
 201417201417JN671223NRTINNRTID67N, K70R, Y115F, M184V, T215F, K219E E6D, V35VL, T39TA, T69N, K82KR, V90VI, K101R, D123E, T139L, I167IV, Q174R, G196E, I202V, E203D, H208HY, R211K, V245M, A272P, T286TA, A288AT, I326V, Q334L, T338S, F346Y, K390R, E399EKB
 203820203820JN671317NRTINNRTIL74V, Y115YF, M184VV108VI, Y181CK101R, D121Y, K122E, I135T, S162SY, I178M, V179VI, T200I, R211G, H221HY, P243PS, V245E, A272P, V276VI, K277KR, L283I, I293V, E297EA, D324DE, I329L, Y342F, R356K, A376S, T377TIM, K390R, A400SB
Kouri (2012)CU112-11CU112-11JQ585478NRTINNRTIM41L, D67N, K70R, T215F, K219EK103S, G190GAV35I, S48T, E53D, V60VI, S68G, K101R, D123E, I135T, K166R, G196E, R211K, A272P, E297R, I329V, G333EB
 CU487-10CU487-10JQ585400NRTINNRTID67N, K70R, M184V, K219QV108VI, Y181CT7A, T39TA, V60VIM, T69TN, K101R, V106VI, D121Y, K122E, I135T, K173T, Q174R, D177E, S191T, G196GE, T200TA, I202V, R211K, F214FL, H221Y, A272P, K277R, T286A, E297A, I326V, I329IL, G335GDB
 CU268-11CU268-11JQ585486NRTINNRTIM41L, D67N, K70G, T215Y, K219NA98G, K103N, Y181C, G190AK20R, K101R, V118I, K122P, I135T, S162C, R172K, D177G, H208HY, R211K, H221Y, V245Q, E248D, A272P, K277R, I293V, E297A, S322AB