<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation V90I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 14
Patients 32
Isolates 36
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2004)ESH_Pat29ESH838AY435371NoneNVP  P4S, K11T, K20R, V21I, V35T, T39R, V90I, D123S, S162D, K173S, D177E, V179I, E194D, I202V, Q207A, R211S, V245Q, E248D, T286A, E291D, V292VI, I293V, P294T, E312N, I326NA
Non-B Workgroup (2005)TK3029TK3029 AZT, 3TC, D4T, DDI, ABCEFVM41L, D67N, K70R, V75M, L210LW, T215F, K219QK103N, G190AE6D, K20R, V35T, K49R, V60I, V90I, I94L, S117A, K122E, D123S, I135T, S162D, K173S, Q174K, D177E, V179I, Q207A, R211N, D218E, L228H, V245K, D250E, A272G, T286A, E291D, I293V, P294T, E312DA
  TK3029a AZT, 3TC, D4T, DDI, ABCEFV  E6D, T7S, V35T, K49R, V60I, V90I, K122E, D123S, T131TA, I135T, S162D, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, A272G, T286A, E291D, I293V, P294TA
Weber (2005)F56326F56326AY6775293TC, D4T, AZT, DDI, ABCNVPM41L, M184V, L210W, T215YK103NK11T, V35T, T39R, K43KE, V90I, K102KR, V118VI, D121H, K122E, I135V, S162A, K173S, D177EG, T200A, I202IV, Q207D, V245Q, A272P, L283I, I293V, E312DA
 M36781M36781-1AY677542D4T, DDI, Unknown, AZT, 3TCNVP, Unknown, EFVV75I, M184V, T215FK103NV35T, V90I, A98AS, K122E, D123N, I132L, I135T, S162H, K173A, D177E, V179I, T200A, Q207A, R211N, V245M, D250DE, K281R, E291D, I293V, P294T, E298EG, E312N, S322AA
  M36781-2AY714403D4T, DDI, Unknown, AZT, 3TC, TDFNVP, Unknown, EFVM41L, V75I, M184V, T215FK103NV35T, V90I, A98S, K122E, D123N, I132L, I135T, S162H, K173A, D177E, T200A, Q207A, R211N, V245M, K281R, E291D, I293V, P294T, E298G, E312N, S322AA
 M55405M55405AY6775643TC, D4TNVPM184VK101E, G190AP4S, K11T, K20R, V21I, V35T, T39K, S68G, V90I, A98S, K122E, D123N, T165I, K166R, K173S, D177E, V179I, T200A, I202V, Q207A, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, E297EA, E312DYA
 F87084F87084AY677580D4T, 3TC, AZTNVPM41L, M184V, T215YA98G, G190AP14A, V35T, T39A, E44ED, V90I, K122E, D123S, I135T, S162Y, K173L, Q174K, D177E, V179I, T200A, Q207E, R211S, V245E, D250E, A272G, I274IV, E291D, V292I, I293V, E312D, Y318X, Y319XA
Ndembi (2010)15017D_P115017GQ409572AZT, 3TCNVPM184VK101KE, G190AE6D, V35T, K49R, I50V, V60I, V90I, K122E, D123N, I135T, K173S, Q174K, D177E, V179I, V189D, I202V, E203D, R206S, Q207D, R211S, Q242EA
Charpentier (2011)30CP 001 399 D4T, 3TCNVPK65R, D67H, T69D, K219EGK103N, Y181C, G190AE6D, K11T, K20R, V35T, T39KR, K43E, S68G, V90I, D121H, K122E, I135M, I142V, S162A, K173A, Q174K, D177E, I178L, T200A, E204K, Q207A, R211S, F214L, L228R, V245E, T286A, E291D, V292I, I293V, E297K, A304E, P313T, I329VA
Fokam (2011)CIRCB-4899CIRCB-4899JQ796151AZT, 3TCNVPD67DN, M184VK103KN, K238TE6D, K11T, E29EG, V35T, T39K, K43E, S68G, V90I, D121H, K122E, I135T, S162H, K173S, Q174K, D177E, D186DE, G196E, T200A, Q207A, R211S, V245Q, T286A, I293V, E297KA
Dvali (2012)R149R149FJ456914D4T, 3TCNVPA62V, K65R, M184IK101E, Y181YC, G190SK30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, V90I, K122E, D123N, A158S, K173L, Q174K, T200A, Q207A, R211S, V245MA
 R144R144FJ456910AZT, 3TCEFVA62V, M184VA98AG, V179DE, G190SK30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, V90I, K122E, D123N, I135T, E138A, K173L, Q174K, Q207A, R211S, V245KA
Reynolds (2012)J0747J0747-1JN652203AZT, 3TCNVPM184V, T215TFISG190A, M230MLP14PL, V35T, E40D, K49R, K64KE, F87FL, V90I, H96HR, K122E, D123N, I135T, S162SN, K173S, V179I, T200A, Q207A, R211S, V245Q, E291D, P294TA
Avidor (2013)1976_FT1976_FTKC184308AZT, 3TCEFVA62V K30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, V90I, K122E, D123NS, K173L, Q174K, T200A, Q207A, R211NSA
Pircher (2013)B1110B1110JX110211D4T, 3TC, AZTNVPK70R, M184V, K219QK103NT27S, V35T, T39KN, V60I, V90I, K122E, D123S, I135T, S162Y, K173A, Q174K, T200A, Q207D, R211K, D218E, L228H, V245Q, E248D, Q258EA
Rawizza (2013)LM3929LM3929KF241482NRTINNRTID67N, K70R, M184V, T215F, K219EV108VI, Y181CP4S, T27S, V35T, T39K, K43A, T69TN, V90I, K102Q, V111I, D123E, I142V, S162Y, K173S, D177DE, V179I, T200A, Q207A, R211K, P243PS, V245T, E248D, T286A, E291D, I293V, P294PTA
Theys (2013)4365143651KC221286TDF, FTCEFVM184IVK103N, P225HE53D, V60I, V90I, D121H, K122E, D123S, I135T, S162H, K173L, Q174R, D177E, I178L, V179I, T200A, Q207D, R211KA
 4064140641KC221204NRTI, TDFNNRTI K103N, Y188C, P225HV90I, D121H, K122E, I135V, A158S, K173A, Q174K, D177E, V179VI, T200A, Q207A, R211KA
 4053040530KC221199NRTI, TDFNNRTID67N, K70R, M184MI, T215DE, K219QK103H, Y181C, G190AK43KR, T69TN, V90I, K101Q, K122E, D123N, S134R, A158S, T165TI, R172K, K173S, Q174K, D177E, I178M, T200A, Q207A, R211SA
Van Zyl (2013)15522995KC423922ABC, 3TCEFVL74V, Y115F, M184VL100LI, K103N, V108VIW88S, V90I, K102Q, K122E, I135T, S162N, S163T, T165I, K173T, Q174K, D177E, V179I, T200A, I202V, Q207A, R211K, H221Y, V241VA, V245E, D250EA
 1307844KC424313AZT, D4T, 3TCNVP, EFVM184VK103N, K238TK20KR, V21I, V35T, V90I, K101KQ, K122E, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, V245Q, E248DA
  1255KC423003AZT, D4T, 3TC, DDINVP, EFVM184VK103N, K238TK20KR, V21I, V35T, V90I, K101Q, K122E, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, V245Q, E248DA
Kolomeets (2014)171171_263KJ870385AZT, 3TCEFVA62V K11T, V35I, E36D, T39K, V90I, K122E, D123N, A158AS, S162X, K173LV, Q174K, D177E, T200I, Q207A, R211S, E248DA
 6565_157KJ870301AZT, 3TCNVPA62V, M184VK101E, G190SK11T, V35T, E36A, T39E, V90I, V106VI, K122E, D123N, A158S, K173L, Q174K, T200A, Q207A, R211S, E248DA
 132132_256KJ870379AZT, 3TCNVPA62V, M184VK103NK11T, V35I, E36D, T39K, V90I, K102N, K122E, D123S, T139R, K173L, Q174K, D177E, T200A, I202V, Q207A, R211S, V245M, E248DA
 118118_145KJ870292AZT, 3TCEFVA62V K11T, V35I, E36D, T39K, V90I, K122E, D123S, I135T, S162C, K173L, Q174K, Q207A, R211S, E248DA
 1414_273KJ870394AZT, 3TCEFVA62V, V75I, M184VK103NK11T, I31L, V35I, T39K, V90I, K122E, D123N, S162Y, K173L, Q174K, D177E, T200A, Q207A, H208HD, R211S, E248DA
 399399_565KJ870611NRTINNRTIA62V K11T, V35T, E36D, T39K, E40ED, K43KE, K49R, I50IV, V90I, K122E, D123NS, A158S, K173S, Q174K, Q207A, R211KN, V245M, E248DA
 1414_197KJ870337AZT, 3TCEFVV75I, M184LK103NK11T, T39K, V90I, K122E, D123N, Y183Y*, F214L, E248DA
 282282_434KJ8705213TC, DDIEFVA62V, M184I I2N, S3N, K11T, V35I, E36D, T39K, V90I, K122E, D123S, I135T, A158S, K173L, Q174K, D177E, T200A, Q207A, R211S, V245M, E248DA
 480480_570KJ870613ABC, 3TCEFVA62V, L74I, V75VAIT, Y115F, M184V, K219KDENY181C, G190SK11T, V35IM, E36D, T39K, T58N, V90I, K122E, D123N, A158AS, K173S, Q174K, T200A, Q207A, R211S, Y232H, V245M, E248DA
 222222_315KJ870428AZT, 3TCNVPA62V, M184VA98AG, K101KE, G190AK11T, V35T, T39K, V90I, K122E, D123N, A158S, K173S, Q174K, D177E, I178IV, V179VI, T200A, Q207A, R211S, T215X, V245M, E248DA
 8888_160KJ870304AZT, 3TCEFVD67N, K70R, M184V, K219QK101E, G190SK11T, V35I, E36D, T39K, V90I, V106I, K122E, D123N, A158S, K173S, Q174K, D177E, T200A, Q207A, V245MT, E248DA
 107107_320KJ870433AZT, 3TCEFVA62V I5IV, K11T, V35I, E36D, T39K, V90I, K122E, D123S, A158S, S162C, K173L, Q174K, D177E, Q207A, R211S, V245M, E248DA
 9797_249KJ870374AZT, 3TCEFVA62V, D67N, K219KEK101E, G190SK11T, V35R, E36D, T39K, I50T, V90I, K122E, D123N, S162A, D177E, R211S, V245M, E248DA