<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation K238T
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 11
Patients 11
Isolates 11
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patSAA01_SAA704AJ577990DDC, AZT, 3TC, D4T, DDI, ABCNVP, EFVK70R, M184V, K219QK103N, K238TE6K, K11T, K20R, V35T, E36A, T39K, K122E, D123N, I142V, S162Y, K173S, D177E, V179I, I202V, Q207A, R211K, F214L, K223Q, L228HA
Seyler (2007)547CS_547 AZT, D4T, 3TC, DDIEFV K103KN, K238TK11T, V35T, T39K, K43E, K102KE, K122E, D123ST, I142V, S162H, K173T, Q174K, D177E, I178L, V179VI, I195L, T200A, Q207A, R211K, V245Q, E248DA
Ndembi (2010)DT1745_05_P11745GQ409602AZT, 3TCNVPM184VG190A, K238TP4H, K11A, A33V, V35K, T39A, K122E, D123N, I135T, I142L, K173L, Q174K, D177E, V179I, T200A, Q207T, R211S, F214LA
Fokam (2011)CIRCB-4899CIRCB-4899JQ796151AZT, 3TCNVPD67DN, M184VK103KN, K238TE6D, K11T, E29EG, V35T, T39K, K43E, S68G, V90I, D121H, K122E, I135T, S162H, K173S, Q174K, D177E, D186DE, G196E, T200A, Q207A, R211S, V245Q, T286A, I293V, E297KA
Aghokeng (2013)HJ3121HJ3121JX983026NRTINNRTIM41L, D67DN, V75M, M184V, L210W, T215YK103N, V108VI, K238TS3C, K11A, V35T, T39K, K43KE, E44ED, K122E, D123N, I135T, I142V, E169D, K173A, Q174K, D177E, I178L, Q207A, R211NS, V245Q, A272P, L283I, T286A, E291D, I293V, E297R, E312D, G335D, R356K, M357R, R358S, G359S, E370Q, A371V, I375V, S379C, K390R, E399D, A400T, T403MA
Rusine (2013)753H753HKC841766AZT, 3TCNVPM184VK103N, K238TK20R, E28A, V35T, T39L, S48T, V60I, K122E, D123S, I135T, K173L, Q174K, D177E, Q207A, R211S, V245E, K281R, T286A, E291D, V292I, I293V, P294T, E297R, E312DA
Sigaloff (2013)JCR017_0JCR017_0JX181984NRTINNRTIM184VK103N, P225H, K238TV35T, T39N, K122E, D123S, I135L, K173A, T200A, Q207A, R211K, V245Q, D250E, A272P, K275R, T286A, E291D, V292I, I293V, P294TA
Aghokeng (2014)CM-1-057CM-1-057KC350321NRTINNRTID67G, K70R, L74I, M184V, T215F, K219EL100I, K103N, K238TK11T, T27S, E28A, V35T, S48T, K64R, T69N, K122E, D123N, I135T, S162A, K173S, Q174K, V179I, I202V, Q207A, V245Q, E248D, T286A, E291D, I293V, P294A, E312D, S322A, Q334H, G335DA
Hassan (2014)RS09000819RS09_819KC568493D4T, 3TCNVPM184VK103N, K238TK11T, V21I, V35T, T39N, V60I, K122E, D123N, N147NK, E169EK, R172RK, K173A, Q174K, D177EK, E194EK, R199RK, T200A, I202V, R206RK, Q207A, R211S, V245Q, E248DN, V261VG, Y271F, A272P, K275Q, R284RK, T286A, E291DN, I293V, P294V, E300EK, E302EK, E305EK, E312DNA
Meini (2015)111128111128KM438261DDI, AZT, 3TCNVPM41L, M184V, T215FLK103N, K238TV35K, V60I, K122E, D123S, I135T, D177E, T200A, Q207A, R211K, D237EA
Boillot (2016)MAT03MAT03KT315971D4T, 3TCNVPM184VK103N, K238TP9S, K20R, E28EGKR, K32KE, V35T, T39KR, K122E, D123N, K173A, Q174QR, D177E, T200A, Q207D, R211K, F214L, I244V, V245K, D250EA