<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation K238R
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 10
Isolates 10
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patGAR01_GAR706AJ577896AZT, 3TCNNRTIM184VK103N, G190AV21I, V35T, T39K, K43E, V106I, D121H, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, R211S, K238RA
Gody (2008)Pt041Pt041 D4T, 3TCNVPM41L, M184VY181C, G190AK49R, V60I, K101D, D121H, K122E, I135T, K173A, Q174K, D177E, I178L, T200A, Q207A, R211S, K238RA
Nyombi (2008)TMS305TMS305EU251857NoneNVP  K11T, K20R, V21I, V35T, T39G, V60I, K122E, D123N, K173S, V179I, I202V, Q207A, R211S, K238R, V245Q, E248D, T286A, K287R, E291D, V292I, I293V, P294T, E312N, A327V, G335D, M357K, G359S, T369A, A371V, I375V, A376TA
Koyalta (2009)67TCHAD-67FJ688198D4T, 3TCNVPD67N, M184V, T215FK101E, G190SK43E, D121H, K122E, D123S, I135T, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, K238RA
Charpentier (2011)121CP001724 D4T, 3TCNVPA62V, V75I, F116Y, Q151M, M184VA98G, Y181CI31L, V35T, T39R, K43E, S68SG, N81ND, D121H, K122E, I135IT, I142V, K173A, Q174K, D177E, G196GE, T200A, Q207A, R211S, K238R, V245E, A272P, K281R, E291D, I293V, E312N, D324EA
Hassan (2014)RS11000442RS11_442KC568516AZT, 3TCNVPM184VY181CI5V, V35T, V60I, D121Y, K122E, D123E, I135T, K173S, Q174K, D177E, V179I, G196E, T200V, Q207A, K238R, V245T, D250E, A272P, E291D, V292I, I293V, E312D, V317GA
Inzaule (2016)1.02121.0212HM164114AZT, 3TCNVP Y181CV35T, E40D, V60I, K122E, D123S, I135T, S162H, K173S, Q174K, D177E, V179I, G196E, Q207A, R211S, K238R, V245E, D250E, K281KR, T286A, E291D, V292I, I293V, E312NA
Kityo (2017)8348283482KY062036NRTINNRTIM41L, D67DN, K70R, L74LI, V75M, M184V, T215F, K219QK101E, Y188LK49E, V60I, T69N, K122E, D123S, I135T, I142K, S162Y, K173S, Q174K, D177E, I178IF, V179I, T200I, Q207A, R211S, F214FL, K223KQ, E224D, L228LH, K238RA
 8351683516KY062070NRTINNRTID67N, K70R, M184V, T215V, K219QK103N, P225HG45GE, T69TN, V118I, K122E, D123N, T165L, K173S, Q174K, N175NY, D177E, G196E, T200A, Q207A, F214L, K238RA
 8307883078KY061636NRTINNRTID67N, K70R, M184V, K219QY188LV60I, K64R, T69N, K122E, D123S, I135T, E138A, K173T, Q174K, V179I, T200A, I202V, Q207K, R211S, F214L, K238RA