<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation M230L
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 7
Patients 9
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Non-B Workgroup (2005)PL5052194398 3TC, D4TNVPM184V, T215FK103N, M230LT7A, E28K, K32KE, V35T, T39DEKN, V118VI, D121H, I135T, I142V, S162C, K173A, Q174KR, D177E, G196D, T200A, Q207A, R211K, V245K, T286A, E291D, V292I, I293V, P294T, E297K, A304E, E312DA
Charpentier (2011)3CP001-039 Unknown, D4T, DDIUnknown, EFVM41L, D67N, K70R, M184L, T215Y, K219QY188L, M230LK11T, V35KR, T39D, V106L, L109I, D121H, K122E, D123S, S134SN, A158S, K173S, Q174K, D177E, V179I, G196E, T200A, I202V, Q207A, R211S, F227Y, V245Q, T286TA, A288AS, I293V, P294T, E312D, D324EA
 133CP001227 D4T, 3TCEFVM184VK103N, V108VI, P225PH, M230LE6D, K11T, K20KR, E28EK, V35T, T39K, K43E, K122E, D123N, K166KR, E169EG, F171Y, K173A, Q174K, D177E, T200A, Q207A, R211S, H221HY, K238KR, V245E, S268SI, A272P, K275KQ, K277R, L282LF, T286A, A288G, E291D, V292I, I293V, P294V, T296TI, E312NA
Fokam (2011)CIRCB-7759CIRCB-7759JQ796153AZT, 3TCEFVM184V, T215FYK103N, M230LK11A, V35T, T39M, D121H, K122E, K173A, Q174K, D177E, G196E, Q207A, R211S, V245Q, E248N, A272P, T286A, E291D, I293VA
Reynolds (2012)A0721A0721-1JN652170AZT, 3TCNVPM184VA98AG, G190A, M230LK11T, G15GR, K20R, V21I, V35T, T39E, K122E, D123N, E138A, Q145C, K173S, Q174K, D177G, V179I, T200A, I202V, Q207A, R211S, L228LR, V245Q, E248D, A272P, T286A, V292I, I293V, P294TA
Aghokeng (2014)TG-2-450TG-2-450KC350166NRTINNRTIM184VK103N, M230LP4H, I5V, V35T, T39L, D121H, K122E, I135T, S162C, E169D, K173S, I178IL, I202V, Q207A, R211S, L228LR, V245Q, T286A, E291D, V292I, I293V, E297K, E312N, G335D, R356K, M357K, R358G, G359S, K366R, E370A, A371V, I375V, A376S, T377Q, K390R, T403M, E413ED, E432D, V435MA
Brooks (2016)2047A2047AKU900876TDF, 3TCNVPK65R, M184IY181C, M230LV35T, V60I, T69S, D121H, K122E, I135T, K173A, Q174K, D177E, I178M, V179I, Q197E, T200A, E204D, Q207A, R211KA
 2077A2077AKU900871TDF, 3TCEFVK65R, M184IK103N, M230L, L234IK11H, V35T, V60I, S68G, V90I, K122E, D123G, I135T, K173L, Q174K, D177E, V179I, G196E, T200TA, I202V, Q207A, R211SA
Lam (2016)2001202420012024KR867846D4T, 3TCEFVT69TADN, M184VK103N, V108VI, F227FL, M230LV35T, V60I, K122E, D123N, I135T, I142V, K173L, Q174K, D177E, V179I, T200A, Q207A, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, A327V, G335DA