<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation P225H
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 8
Patients 17
Isolates 18
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Steegen (2009)BV114BV114-2EU8721373TC, D4T, AZTEFV K103N, P225HV35T, W88C, D121H, R125RK, I135T, I142V, D177E, I178L, T200A, E204K, Q207E, R211QA
 BV147BV147-1EU8785483TC, D4TEFVM184V, T215FK103N, P225HI31L, V35T, T39N, D121Y, K122E, D123E, I142V, S162C, D177E, I178L, Q207E, R211KA
Avidor (2013)1996_FT1996_FTKC184324AZT, 3TCEFVM184VK103N, V108I, P225HV35L, E36N, I37F, T39M, K122E, D123S, A158AS, K173L, Q174K, D177E, T200A, E203D, Q207A, R211S, V245MA
 1978_MT1978_MTKC184309AZT, 3TCEFVA62V, M184VK103N, P225HK30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, K122E, D123N, A158S, K173L, Q174K, D177E, Q207A, R211S, L228LH, V245MA
Sigaloff (2013)MBA054_0MBA054_0JX182020NRTINNRTIM184VK103N, P225HE6D, V35T, E40D, V60I, V118I, K122E, D123S, I135T, T165L, K173A, Q174N, D177E, T200TA, Q207A, R211S, F214L, V245E, D250E, A272P, K277R, K281R, T286A, E291D, I293VA
 JCR017_0JCR017_0JX181984NRTINNRTIM184VK103N, P225H, K238TV35T, T39N, K122E, D123S, I135L, K173A, T200A, Q207A, R211K, V245Q, D250E, A272P, K275R, T286A, E291D, V292I, I293V, P294TA
Theys (2013)4365143651KC221286TDF, FTCEFVM184IVK103N, P225HE53D, V60I, V90I, D121H, K122E, D123S, I135T, S162H, K173L, Q174R, D177E, I178L, V179I, T200A, Q207D, R211KA
 4064140641KC221204NRTI, TDFNNRTI K103N, Y188C, P225HV90I, D121H, K122E, I135V, A158S, K173A, Q174K, D177E, V179VI, T200A, Q207A, R211KA
Aghokeng (2014)CI-1-57-CI-1-57-KC350128NRTINNRTIM184VK103N, P225HP1S, V35T, T39K, K43E, S68G, T69TI, V90VI, K102Q, D123E, T139TK, S162H, K173S, D177E, T200A, Q207A, R211K, V245Q, E248NA
Kolomeets (2014)421421_666KJ870683AZT, 3TCEFVA62V, M184VK103N, P225H, K238KTK11T, V35I, E36D, T39K, K122E, D123N, A158S, I167IF, K173L, Q174K, D177E, T200A, Q207A, R211S, I244V, V245M, E248DA
 102102_286KJ870404AZT, 3TCEFVA62V, M184VK103N, P225HK11T, K20KR, V35I, T39E, K122E, D123N, I135T, A158S, K173L, Q174K, D177E, T200A, Q207A, R211S, E248DA
 3939_642KJ8706673TC, DDIEFVA62V, K65R, M184IK101E, Y181C, G190S, P225HK11T, V35I, E36D, T39K, K122E, D123N, A158S, K173LS, Q174R, D177E, G196E, T200A, Q207A, R211S, E248DA
 3232_267KJ870388AZT, 3TCEFVA62V, M184VK103N, P225HK11T, V35I, E36D, T39Q, D123N, I135T, N147NH, A158S, K173A, Q174K, D177E, T200A, Q207A, R211S, E248DA
 160160_189KJ8703303TC, DDIEFVA62V, K65R, V75IY181C, G190S, P225HK11T, V35I, E36D, T39N, K103R, K122E, D123N, A158S, Q174K, D177E, T200A, Q207A, R211S, V245M, E248DA
 3232_324KJ870437AZT, 3TCEFVA62V, M184VA98AG, K103N, P225HK11T, V35IM, E36D, T39Q, D123N, I135IT, A158S, K173ALSV, Q174K, D177DE, V179VI, T200A, Q207A, R211S, H221HY, E248DA
Wallis (2014)4128141281KM458600NRTINNRTIM184VG190A, P225HV35T, T39A, E40D, K122E, D123N, I135T, I142V, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, F214LA
 4123541235KM458480NRTINNRTIM184VK103N, V108VI, P225HV35T, T39K, K122E, D123S, I135IT, A158S, K173S, Q174K, D177E, T200A, Q207A, R211HA
Steegen (2016)GFKZB161GFKZB161KU128052TDF, 3TC, FTCEFVA62AV, K70E, L74LI, M184V, K219RK103N, P225HE6K, K20KR, K22KR, V35T, A98S, K122E, I135T, I142V, K173S, V189I, T200TA, I202V, Q207KNRS, R211K, L228R, D237DE, V245Q, E248D, A272P, V276I, L283I, T286A, E291D, I293V, P294T, E297KR, E312D, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376V, T386A, E399ED, A400TA