<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation V179T
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 12
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2004)ESH_Pat55ESH485AY435281NoneNVP  E6N, V35T, K49KR, V60I, K64R, K122E, D123G, I135T, I142V, K173AS, Q174K, D177E, V179T, T200A, Q207E, R211S, V245K, D250E, V276I, K277KR, T286A, K287KR, E291D, I293V, P294AT, E312DA
Eshleman (2004)ESH_Pat169ESH672AY435337NoneNVP Y181YC, Y188YC, G190GAE6EK, K11KT, K20R, V35T, K49KR, K103X, K122KE, D123X, K126KR, T165TI, K173S, D177E, V179T, Q207A, V245Q, E248N, A272P, K277R, Q278H, T286A, I293V, E312DA
Deshpande (2009)Pat111236RTFJ530830D4T, 3TCNVPM41L, D67N, V75M, M184V, L210W, T215YK103S, G190AK11E, V35T, E44ED, V60I, V106I, V118VI, D121Y, K122E, D123G, I135T, K173S, Q174K, D177E, V179T, Q197K, T200A, Q207A, R211NS, K223KQ, F227FY, V245E, D250EA
Ndembi (2010)13305D_P113305GQ409552ABC, AZT, 3TCNVPM184VK103N, G190AE6K, K11T, G15R, L26M, V35T, T39M, V60I, K122E, D123S, I135T, T165I, K173L, Q174K, D177E, V179T, T200I, I202V, Q207E, F214LA
 DT2794_05_P12794GQ409609AZT, 3TC, TDFNVPM41L, D67N, K70R, M184V, T215Y E6D, V35T, V60I, K64R, K122E, D123S, I135T, K173A, Q174K, D177E, V179T, T200A, E203K, Q207E, R211KA
Inzaule (2013)227227JQ914068AZT, 3TCNVP  K11T, K20R, V21I, V35T, T39E, V106I, D123N, T139A, K173S, D177G, V179T, T200A, I202V, Q207A, R211NA
Pircher (2013)B1128B1128JX110229D4T, 3TC, AZTNVPD67DG, M184V, T215YK101E, G190AE6D, K11T, E28K, V35T, T39N, D86DE, D123N, K166R, D177E, I178F, V179T, T200A, Q207A, R211KA
Hassan (2014)RS09000807RS09_807KC568489D4T, 3TCEFV  K20R, V21I, V35T, T39R, K43KE, G45GE, K122E, D123GS, I142IT, K166R, K173A, Q174R, D177E, I178L, V179T, T200TA, Q207A, R211K, F214L, D250E, A272P, K277R, T286A, A288AT, E291D, V292I, I293V, E312D, V317AA
Meini (2015)109273109273KM438240AZT, 3TC, DDIEFVM41L, L74V, M184V, T215YL100I, K103NE28A, K32Q, V35T, T39A, V60I, S68SG, D123E, I135T, K173A, Q174K, D177E, I178IM, V179T, T200A, Q207A, R211SA
Ndahimana (2016)14301430KU922856TDF, 3TCNVP G190AS48T, K49R, K122E, D123N, E138A, S162C, K173S, Q174K, D177DE, V179T, T200A, R206RK, Q207AD, R211K, V245QA
 12041204KU922893TDF, 3TCNVPA62V, K65R, M184VK103N, Y181CT39TA, E44ED, K122E, D123S, I135T, K173S, Q174K, D177E, V179T, T200A, Q207D, R211K, L228LR, P243T, V245EA
 13181318KU922852ABC, 3TCNVPM184MVK103NK43R, K122E, D123N, I135T, I142IV, K173S, D177E, I178IL, V179T, T200A, Q207A, R211S, F214L, V245QA