<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation E138Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 10
Patients 22
Isolates 22
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Lwembe (2007)NYU3030FAPR04DQ679543AZT, 3TC, DDIEFVD67G, K70R, K219QL100I, K103NV35T, V60I, K122E, D123S, I135T, E138Q, K173L, Q174K, D177E, T200A, Q207A, R211SA
Kouri (2012)CU1-10CU1-10JQ585357NRTINNRTIL74V, M184VK103NV35T, K102Q, K122E, D123S, E138Q, S162A, F171Y, K173S, Q174K, D177E, T200A, Q207A, R211N, V245K, E248D, D250E, A272P, K277R, T286A, E291D, I293V, P294T, V317A, S322A, A327SA
Avidor (2013)1612_MN1612_MNKC184212TDF, FTCEFVM184VK103N, V108IK30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39A, E40D, V60I, K102Q, D121H, K122Q, I135T, E138Q, K173A, Q174K, I178L, V179I, Q197L, T200A, Q207A, R211S, F214L, V245KA
Rusine (2013)468H468HKC841711AZT, 3TCNVPM184VK103NK20KR, V35T, I47L, K49KR, I50V, V60I, A98AS, K102KN, K122E, D123NS, I135T, E138Q, I142IV, K173S, Q174K, D177E, V179I, E194D, T200A, Q207A, R211S, F214FL, V245E, T286A, I293V, P294T, E312D, I326ITA
Sigaloff (2013)JFP048_0JFP048_0JX182009NRTINNRTIM41L, D67N, K70R, M184V, T215F, K219EG190AK11T, K20R, V35T, T39N, K43R, E44D, V60I, T69N, K102Q, K122E, D123S, E138Q, S162A, K173T, D177E, I178F, V179I, G196K, T200K, E203D, Q207A, R211K, L228H, V245Q, E248D, K259KR, K277R, Q278H, E291D, V292I, I293V, E312KA
Acharya (2014)DGP030DGP030KJ185200AZT, 3TCNVPD67N, K70R, M184V, K219QK103NV35T, V60I, K122E, D123S, I135T, E138Q, I142V, S162A, T165I, K173S, Q174K, D177E, V179I, Q197E, T200A, Q207A, R211K, V245K, D250E, T286A, E291D, V292I, I293V, P294TA
Jenabian (2015)DR06DR06KF735817NRTINNRTIM184V, T215YK103NK11M, K20R, V35T, S48T, K49R, V60I, K102Q, D121Y, K122E, E138Q, E169D, K173A, Q174K, D177E, I178IM, G196E, Q207E, R211K, F214L, V245K, E248D, A272P, K281R, L283LF, E291D, I293V, E297R, A304E, E312N, G335DA
Meini (2015)118221118221KM438316AZT, 3TC, DDINVPD67N, K70R, M184V, T215F, K219QK103NK20R, V35T, T39A, V60I, K122E, D123S, I135T, E138Q, Q145C, K173S, Q174K, D177E, T200A, I202V, Q207A, R211SA
Brooks (2016)2003A2003AKU900868TDF, 3TCEFVD67G, K70Q, M184VK101P, K103SE6K, K11A, V35T, V60I, K122E, D123S, I135T, E138Q, I142T, K173S, Q174K, D177E, T200A, Q207A, R211SA
Kityo (2017)8319583195KY061751NRTINNRTIM184V, L210W, T215YG190AV60I, S68SG, A98AS, K122E, D123DG, I135T, E138Q, K173S, Q174K, D177E, V179I, T200S, I202IV, Q207A, R211NS, F214LA
 8294482944KY061508NRTINNRTIM41L, D67N, K70R, V75M, M184V, T215F, K219QG190AV60I, K122E, D123S, I135T, E138Q, I142V, K173S, Q174K, D177E, V179I, T200A, E203D, Q207A, R211SA
 8327083270KY061825NRTINNRTIM184V, T215FK101E, G190AV60I, S68SG, D121H, K122E, D123S, E138Q, K173A, Q174K, N175NY, D177E, V179VI, Q197K, T200A, I202V, E203A, Q207D, R211KA
 6603466034KY061404NRTINNRTIM184VK103NV60I, T69S, E138Q, K166R, K173S, Q174QL, D177E, V179I, T200A, I202V, Q207D, R211KA
 8317483174KY061730NRTINNRTIM41L, D67N, M184V, L210W, T215YV106AE44D, K49R, I94L, A98AS, K122E, D123S, E138Q, S162SN, K173A, D177DE, I178ILM, V179I, G196E, T200A, Q207AD, H208HYA
 8325683256KY061811NRTINNRTIM41L, D67N, K70EG, M184MIT, K219RK103N, K238TV60I, K122E, I135T, E138Q, K173S, Q174K, D177E, T200A, I202V, Q207A, H208L, R211RK, F214L, L228LRA
 8330783307KY061862NRTINNRTID67N, K70R, M184V, K219QK101E, G190AV60I, K122E, D123N, I135T, E138Q, K173L, Q174K, D177E, V179I, Q207D, F214LA
 8300483004KY061566NRTINNRTIM41L, D67N, V75M, M184V, L210W, T215YG190AK43KQ, E44ED, V60I, K101Q, K102Q, V118VI, K122E, D123S, I135T, E138Q, I142V, K173A, Q174K, D177E, V179I, G196E, T200A, Q207A, R211NA
 8349483494KY062048NRTINNRTID67N, K70R, M184V, K219QK103N, M230MLV60I, K102R, K104KR, K122E, D123N, I135T, E138Q, S162C, K173A, Q174R, D177E, I178L, V179I, E203EK, Q207AD, R211RS, W229WCA
 8328983289KY061844NRTINNRTIM41L, M184V, L210W, T215YK103NK43KQ, E44ED, V60I, A98S, V118VI, K122E, D123N, I135M, E138Q, K173L, D177G, Q197E, T200A, Q207A, R211KA
 8328783287KY061842NRTINNRTIM41L, M184V, L210LW, T215FK103NS48T, V60I, K122E, D123N, I135V, E138Q, S162ST, K173A, D177E, I178M, V179I, T200A, Q207A, L228LRA
 8299282992KY061554NRTINNRTIM41L, L74I, M184V, L210W, T215YK103NK43KQ, E44D, V118I, K122E, D123N, I135T, E138Q, I142V, S162SG, K166R, K173S, D177E, G196E, T200A, E203K, Q207D, H208Y, R211K, K223E, L228RA
 8313483134KY061691NRTINNRTIM41L, M184V, L210L*W, T215YK103NS48SL, P52PS, V60I, K122E, D123N, I135T, E138Q, K173S, Q174K, D177E, T200A, Q207DE, L228LRA