<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation E138A
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 12
Patients 14
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2004)ESH_Pat76ESH850AY425356NoneNVP  K11T, K20R, V21I, V35T, T39K, K122E, D123S, E138A, K173S, D177G, V179I, T200A, I202V, Q207A, R211NS, V245Q, E248DY, T286A, E291D, V292T, I293V, P294T, L295MA
Eshleman (2004) SE850_7dAY428728NoneNVP  K11T, K20R, V21I, V35T, T39K, K122E, D123S, E138A, K173S, D177G, V179I, T200A, I202V, Q207A, R211N, V245Q, E248D, T286A, E291D, V292T, I293V, P294T, L295MA
Richard (2004)RNJCR41RNJCR41AY556837AZT, 3TC, D4T, DDINVPM41L, D67N, K70R, V75IY181C, G190AK11T, K20R, V21I, V35T, D123S, E138A, S162A, T165L, K173S, V179IA
Non-B Workgroup (2005)UK4280UK4280AY901826AZT, 3TCNVPM184VA98G, K101E, G190AK11T, K20R, V35T, E42K, K122E, D123S, I135T, E138A, K173S, Q174K, D177G, V179I, I202V, Q207D, R211S, F214LA
Weber (2005)M41971M41971AY677568AZT, 3TCNVPM41L, D67N, K70KR, M184V, T215F, K219QY181IE6D, T27S, V35T, T39A, V60I, K122E, D123S, I135T, E138A, I142IV, K173A, Q174K, V179I, Q207A, F214L, D218E, L228LH, V245M, D250DE, A272P, T286A, A288T, I293V, P294TA
Sylla (2008)D607D607_C2DQ991656AZT, 3TCNVPM41L, D67N, M184V, L210W, T215YK101E, G190AI5V, E6K, K11T, V35T, E36A, T39K, K43E, E53D, K102Q, K122E, D123S, I135T, E138A, S162D, K173S, V179I, T200A, Q207A, R211K, V245Q, T286A, E291D, I293V, P294T, E312D, I326V, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T386A, K390R, A400T, T403M, W410Y, E432D, V435AA
Dvali (2012)R117R117FJ456906AZT, 3TCNVPA62V, M184VK101E, G190SK30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39S, W88C, K122E, D123N, I135T, E138A, K173S, Q174K, Q207A, R211S, F214LA
 R144R144FJ456910AZT, 3TCEFVA62V, M184VA98AG, V179DE, G190SK30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39K, V90I, K122E, D123N, I135T, E138A, K173L, Q174K, Q207A, R211S, V245KA
Reynolds (2012)A0721A0721-1JN652170AZT, 3TCNVPM184VA98AG, G190A, M230LK11T, G15GR, K20R, V21I, V35T, T39E, K122E, D123N, E138A, Q145C, K173S, Q174K, D177G, V179I, T200A, I202V, Q207A, R211S, L228LR, V245Q, E248D, A272P, T286A, V292I, I293V, P294TA
 H0534H0534-1JN652196AZT, 3TCEFVM184VY181IK11T, V21I, V35T, V60I, K101Q, K122E, D123N, E138A, P157PS, K173L, D177G, V179I, I202V, Q207A, R211K, V245E, D250E, A272P, K277R, T286A, V292I, P294T, L295MA
Inzaule (2013)7373JQ914097AZT, 3TCNVPM184VV108I, Y181II31IL, V35T, T39L, K64KR, D121H, K122E, E138A, I142V, T165TM, K173N, Q174K, D177E, V179I, Q207E, R211KA
Rusine (2013)717H717HKC841741AZT, 3TCNVP  K20R, V35T, T39N, E44ED, V60I, K122E, D123S, I135T, E138A, I142V, K173S, Q174K, V179I, Q207A, R211RS, F214L, D250E, A272P, T286A, E291D, V292I, I293V, P294T, E312DA
Sigaloff (2013)JCR070_0JCR070_0JX181992NRTINNRTIM184V, K219QG190AE6D, K20R, V35T, E40D, E42K, K43R, K46R, V60I, K122E, D123N, I135T, E138A, K173S, Q174K, D177E, V179I, T200A, I202V, E203K, Q207D, R211K, V245Q, E248D, D250E, T286A, E291D, I293V, P294T, E312DA
 JCR066_0JCR066_0JX181991NRTINNRTI  V35T, E40ED, V60I, D121H, K122E, D123S, I135T, E138A, I142V, S162A, K173S, Q174K, V179I, T200E, I202V, Q207A, R211S, E248D, L283I, T286A, E291D, V292I, I293V, P294T, L295MA
Theys (2013)1995619956KC219996NRTI, TDFNNRTID67N, K70R, T215I, K219EG190SV60I, K122E, D123S, I135T, E138A, K173S, Q174K, V179I, T200A, Q207E, R211K, F214LA