<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation V106I
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 16
Patients 18
Isolates 20
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Montes (2004)MB_patGAR01_GAR706AJ577896AZT, 3TCNNRTIM184VK103N, G190AV21I, V35T, T39K, K43E, V106I, D121H, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, R211S, K238RA
Richard (2004)RNJCR58RNJCR58AY556819AZT, 3TC, ABCEFVM184VY188HK11T, V21I, V35T, V106I, K122E, D123S, I135L, I142V, K173S, Q174K, D177E, I178L, V179I, T200AA
Weber (2005)F51354F51354AY677539AZT, 3TC, DDC, D4T, DDINVP, EFVD67DN, K70KR, L74LV, T215FA98G, K103N, Y181CK11T, K20R, V21I, V35T, T39L, N57NI, T69X, V106I, D123N, I135L, D177E, I178L, V179I, T200A, I202V, Q207A, R211X, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E312GA
Lwembe (2007)NYU6262MMAR03 AZT, 3TCNVPD67N, K70R, T215F, K219EG190AV35T, E40D, V60I, K101Q, V106I, K122E, D123G, K173S, Q174K, D177E, I178M, V179I, T200A, Q207A, R211SA
  62MMAY04 AZT, 3TCNVPD67N, K70R, T215I, K219EY181C, G190AV35T, E40D, V60I, K101Q, V106I, K122E, D123G, K173L, Q174K, D177E, V179I, T200A, Q207A, R211SA
Deshpande (2009)Pat111236RTFJ530830D4T, 3TCNVPM41L, D67N, V75M, M184V, L210W, T215YK103S, G190AK11E, V35T, E44ED, V60I, V106I, V118VI, D121Y, K122E, D123G, I135T, K173S, Q174K, D177E, V179T, Q197K, T200A, Q207A, R211NS, K223KQ, F227FY, V245E, D250EA
Charpentier (2011)CR-55CR-55FJ688261AZT, 3TCNNRTI  K11T, V35T, S48T, V106I, K122E, D123N, I135IT, I142IV, K173K*IL, V179I, T200A, E204ED, Q207A, R211S, F214L, V245VELQ, A272P, I293V, P294T, E312D, I326IV, Q334QHA
Dvali (2012)R072R072FJ456901AZT, 3TCEFVM184VK103N, V108VIV35L, E36N, I37F, T39K, V106I, K122E, D123S, I135T, A158S, K173L, Q174K, D177E, Q207A, R211S, V245MTA
Fourati (2012)94609749460974JQ395871NRTINNRTI K103N, V108IK11T, V35T, T39K, V106I, K122E, D123N, I142V, E169D, K173S, D177E, I178L, G196K, T200A, I202V, Q207A, R211K, F214L, H221Y, E224D, V241IA
Avidor (2013)1966_MT1966_MTKC184299TDF, 3TCEFVK65KR, M184VK101E, Y181C, G190SK30Q, K32G, A33C, L34T, V35L, E36N, I37F, T39V, V106I, D121H, K122E, D123S, I135T, K173S, Q174K, D177E, T200A, Q207A, R211S, L228LR, V245MA
Inzaule (2013)227227JQ914068AZT, 3TCNVP  K11T, K20R, V21I, V35T, T39E, V106I, D123N, T139A, K173S, D177G, V179T, T200A, I202V, Q207A, R211NA
  227JQ914091AZT, 3TCNVP  K11T, K20R, V21I, V35T, T39E, V106I, D123N, K173S, D177G, V179IT, T200A, I202V, Q207A, R211NA
Thiam (2013)3713-HALD3713-HALDJN673567NRTINNRTIM184VK101E, G190AE6A, V35T, E36A, T39K, K43E, V106I, D121H, K122E, K173S, D177E, V179I, T200A, Q207A, R211RK, V245Q, A272P, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335DA
Aghokeng (2014)TG-3-626TG-3-626KC350319NRTINNRTIV75I, M184V, T215F, N348IK103NV35T, T39A, V90VI, V106I, K122E, D123S, I132L, I135T, S162Y, K173S, V179I, Q207A, R211K, F214L, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, E312D, I326V, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, A376V, A400T, T403R, W410CA
Kolomeets (2014)414414_633KJ870659AZT, 3TCEFVD67DN, K70KR, M184V, T215TNSY, K219KQK101E, G190SE6K, K11T, V35T, E36D, T39N, V106I, K122E, D123S, S162C, K173L, Q174K, D177E, G196E, Q197QKR, T200A, Q207A, R211S, V245M, E248DA
 326326_462KJ870541AZT, 3TCEFVA62V, M184VK101E, G190SK11T, V35I, E36D, T39K, R72RK, V106I, K122E, D123N, A158S, K173A, Q174K, D177E, Q207A, R211S, V245M, E248DA
 8888_160KJ870304AZT, 3TCEFVD67N, K70R, M184V, K219QK101E, G190SK11T, V35I, E36D, T39K, V90I, V106I, K122E, D123N, A158S, K173S, Q174K, D177E, T200A, Q207A, V245MT, E248DA
Meini (2015)109276109276KM438252AZT, 3TCNVPK70R, M184EK103N, F227LV35T, V60I, V90I, V106I, K122E, D123N, I135T, T139R, S162H, K173L, Q174K, I178L, V179I, D185E, T200A, Q207A, R211NA
Boillot (2016)VIR32VIR32KT315993D4T, 3TCEFVM41L, D67N, K70R, M184V, T215YA98G, Y188LK11T, V35T, T39A, V60I, V106I, D121Y, K122E, D123G, I135T, I142V, K173S, Q174K, D177E, V179I, G196E, Q207A, R211S, F214L, E224D, D237E, V245EA
Steegen (2016)GFKZB174GFKZB174KU128078TDF, 3TC, FTCNVP, EFVM184VA98G, Y188LP4H, K11T, V35T, K46Q, V106I, K122E, D123N, I135T, I142V, S162C, K173S, V179I, T200A, I202V, Q207A, R211S, F214L, L228H, V245Q, E248D, R284K, T286A, E291D, V292I, I293V, G335D, R356K, M357R, G359T, T369TAA