<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation K103R
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 9
Patients 12
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Charpentier (2011)CR-20CR-20FJ688226AZT, 3TCNNRTID67DN, K70KR, V75VI, M184V, T215TFIS, K219KQV179D, G190AE6K, K11T, V35T, K43KN, K103R, V118I, K122E, D123N, I132IL, I142V, K173S, I202V, Q207A, R211S, F214L, V245Q, E248D, A272P, E291D, V292I, I293V, P294T, L295M, E297Q, E312D, I326VA
Pircher (2013)B1108B1108JX110210D4T, 3TC, AZTNVPD67N, K70R, V75A, F77L, Q151M, M184V, T215I, K219QV179E, Y181C, G190AV35T, T39N, K46KQ, V60I, K73L, K101R, K103R, V111I, K122E, D123S, I135T, I142V, K173A, T200A, Q207E, R211K, F214L, D218E, L228H, V245QA
Sigaloff (2013)JFP103_0JFP103_0JX182011NRTINNRTIM41L, D67N, K70R, L74I, M184V, L210W, T215F, K219QA98G, K101E, G190AK20R, E28K, K32Q, V35T, T39E, T69N, I94L, K103R, K122E, D123N, S162SN, K173S, Q174K, D177E, T200A, Q207A, R211N, D218E, V245Q, E248D, D250E, S251D, R284K, T286A, E291D, V292I, I293V, P294T, E312NA
Aghokeng (2014)TG-1-035TG-1-035KC350294NRTINNRTID67G, T69D, K70*R, M184V, T215F, K219QK101N, Y181C, G190AT7A, V8I, K11T, I31L, V35T, E36A, T39K, K43E, T58TN, V90I, I94IL, K103R, V106VL, D121H, I135IV, S162H, K173L, D177E, V179I, T200A, Q207E, R211K, L228H, P243PL, V245Q, I270IM, T286A, E291D, V292I, I293V, I326V, G335D, N348T, R356K, M357K, G359S, T369V, A371V, I375V, A376V, I382T, K390R, A400T, T403RA
 CI-1-456CI-1-456KC350389NRTINNRTIM184MIG190GAE6K, K11T, V35T, E36A, T39K, K43E, K102KQ, K103R, K122E, D123N, I142V, S162DY, K173S, D177E, V179I, T200TA, Q207A, R211K, F214L, V245Q, E248EK, K249KM, D250EA
Kolomeets (2014)160160_189KJ8703303TC, DDIEFVA62V, K65R, V75IY181C, G190S, P225HK11T, V35I, E36D, T39N, K103R, K122E, D123N, A158S, Q174K, D177E, T200A, Q207A, R211S, V245M, E248DA
Steegen (2014)11ZAKS12411ZAKS124KJ176406D4T, 3TCEFVM184VV179DV35IT, K64R, K103R, K122E, D123N, I135T, I142V, K173S, D177N, I202V, R211S, F214L, V245Q, T286A, E291D, V292I, I293V, P294T, E308K, E312D, G335DA
Brooks (2016)2009A2009AKU900869TDF, 3TCNVP, EFVK65R, M184VA98G, V179F, Y181C, G190AK20R, V35T, K43KR, V60I, K103R, D121Y, K122E, I135T, K173A, Q174K, D177E, T200A, Q207RS, R211NSA
Kityo (2017)8289682896KY061461NRTINNRTIK65R, V75I, M184V, K219EA98G, Y181CV60I, S68G, K102Q, K103R, V118VI, K122E, D123S, I132L, S162C, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, F214LA
 8294682946KY061510NRTINNRTIM41L, A62V, D67N, M184V, T215YV179D, G190AE44D, K102KR, K103R, V111I, K122E, D123N, D177N, I178M, T200A, E203D, Q207ADNT, H208Y, R211KN, H221YA
Svard (2017)1st_711st_71KX775255AZT, 3TCEFVM41L, V75M, M184V, T215YA98G, K101E, G190A, F227LP4H, K11A, E28K, K32E, V35T, V60I, K103R, D121H, K122E, D123S, I135T, K173S, Q174K, D177E, T200A, Q207A, R211H, D250EA
 1st_881st_88KX7752643TC, D4TNVPM41L, M184V, T215F, K219WV179D, Y188LE6K, V35T, T39R, K43E, E44D, V60I, S68G, K103R, V118I, K122E, D123S, I135T, K173S, Q174K, N175Y, I180L, T200A, I202V, Q207E, R211K, F214L, V245QA