<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Reverse Transcriptase Inhibitors

Subtype A
Gene RT
Mutation K101Q
Rx >= 1 NNRTI
(+/- NRTI)
IncludeMixtures No
References 10
Patients 14
Isolates 17
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# NRTIs NNRTIsNRTIDRMs NNRTIDRMs OtherMutSubtype
Eshleman (2004)ESH_Pat88ESH421AY435267NoneNVP  K11T, K20R, V21I, V35T, T39R, V60I, K101Q, D110DH, D123N, K173A, D177G, V179I, T200A, I202V, Q207A, R211S, V245Q, E248N, D250E, A272V, R284K, E291D, V292I, I293V, P294T, E312DA
Weber (2005)95F527295F5272AY677605AZT, 3TCNVP G190GAE6N, V21I, V35I, K101Q, K122E, D123S, I135T, S162C, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, T286A, E291D, V292VI, I293V, P294T, E312D, S322SAA
Baxter (2006)12-21202120-30715DQ880034NRTINNRTIM41L, D67N, L74V, M184V, L210W, T215Y, K219RY181C, G190AT39A, E44D, V60I, K101Q, V118I, K122E, D123N, I135T, K173S, Q174K, V179I, T200A, Q207E, H208Y, R211K, H221C, V245QA
  2120-40510DQ880035NRTINNRTIM41L, D67N, L74V, L210W, T215Y, K219RV106A, Y181C, G190AT39A, E44D, V60I, K101Q, V118I, K122E, D123N, I135T, K173S, Q174K, V179I, T200A, Q207E, H208Y, R211K, H221C, V245QA
 48-12041204-30709DQ877748NRTINNRTIM41L, D67N, L74V, M184V, L210W, T215Y, K219NK103S, Y181C, G190AP4S, V35T, T39A, E44D, K64R, K101Q, K122E, D123S, T165I, K173S, Q174K, D177E, I178L, V179I, T200A, I202V, E203D, Q207N, H208Y, R211N, W212C, H221Y, L228H, V245T, D250E, A272P, K281R, I293V, P294T, G335D, M357R, G359S, T369A, A371V, I375V, A376V, T377M, T386SA
 48-30453045-30317DQ877957NRTINNRTID67N, L74V, Y115F, M184V, T215F, K219QY181C, G190AT7A, K11T, K20KR, V35T, T39R, K43E, K101Q, D121H, K122E, D123S, I135T, K173S, Q174K, N175Y, D177E, G196E, Q207A, V245Q, T286A, E291D, K311R, M357K, R358K, G359S, K366R, T369V, E370D, A371V, I375V, A376I, T386IA
Lwembe (2007)NYU3333FMAR03 AZT, 3TC, DDIEFVD67N, K70RK103NK11Q, V35T, V60I, K101Q, D121H, K122E, I135T, T139M, S162N, K173S, Q174K, D177E, V179I, T200A, Q207A, R211SA
  33FFEB04 AZT, 3TC, DDIEFVD67N, K70R, K219QK103NK11Q, V35T, V60I, K101Q, D121H, K122E, I135T, S162N, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, D218EA
 NYU6262MMAR03 AZT, 3TCNVPD67N, K70R, T215F, K219EG190AV35T, E40D, V60I, K101Q, V106I, K122E, D123G, K173S, Q174K, D177E, I178M, V179I, T200A, Q207A, R211SA
  62MMAY04 AZT, 3TCNVPD67N, K70R, T215I, K219EY181C, G190AV35T, E40D, V60I, K101Q, V106I, K122E, D123G, K173L, Q174K, D177E, V179I, T200A, Q207A, R211SA
Steegen (2009)BV223BV223-2EU8721503TC, D4T, ABCEFVM184VG190SV35T, K101Q, K122E, D123S, K173S, V179I, Q197H, T200A, Q207A, R211SA
Charpentier (2011)117CP 001 201 D4T, 3TCEFVM184VK103NK11T, V35T, T39N, V60I, T69S, K101Q, D121H, K122E, D123S, I135T, I142V, K173S, Q174K, D177E, I178L, G196E, T200E, Q207A, V245Q, E248D, S251I, A272P, T286A, I293V, E297K, E312DA
Reynolds (2012)H0534H0534-1JN652196AZT, 3TCEFVM184VY181IK11T, V21I, V35T, V60I, K101Q, K122E, D123N, E138A, P157PS, K173L, D177G, V179I, I202V, Q207A, R211K, V245E, D250E, A272P, K277R, T286A, V292I, P294T, L295MA
Aghokeng (2013)HJ3146HJ3146JX983027NRTINNRTIM41L, D67N, M184V, L210W, T215YK103NP4K, K11A, D17N, E28A, V35T, I94L, K101Q, V111I, D121H, K122E, I135T, S162C, E169A, K173A, Q174K, D177E, G196E, T200A, Q207A, H208Y, R211D, V245Q, E248D, T286A, A288S, E291D, E297K, I329V, G335D, N348T, M357R, R358K, G359S, A371L, I375V, T377Q, S379C, T403M, E404DA
Theys (2013)4053040530KC221199NRTI, TDFNNRTID67N, K70R, M184MI, T215DE, K219QK103H, Y181C, G190AK43KR, T69TN, V90I, K101Q, K122E, D123N, S134R, A158S, T165TI, R172K, K173S, Q174K, D177E, I178M, T200A, Q207A, R211SA
 4017740177KC221187NRTI, TDFNNRTID67N, K70R, K219QK103N, K238KTV60I, K101Q, D121H, K122E, I135T, K173S, Q174K, D177E, V179I, Q207A, R211S, F214LA
Van Zyl (2013)13071255KC423003AZT, D4T, 3TC, DDINVP, EFVM184VK103N, K238TK20KR, V21I, V35T, V90I, K101Q, K122E, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, V245Q, E248DA