<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype G
Gene IN
Mutation L74M
Rx II-naive
IncludeMixtures No
References 5
Patients 6
Isolates 6
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Njai (2006)MP141799CM.1417AM279377None  L74MK14R, V31I, L101I, T112I, T122TI, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234I, L242LHG
 MP141699CM.1416AM279386None  L74MK14R, V32I, M50I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234IG
Brennan (2008)18-918-9EU618109None  L74MK14R, V31I, L101I, K111T, T112TI, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
Eshleman (2009)ABB125-98ABB125-98FJ480306None  L74MK14R, K34R, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, M275V, S283GG
Gafarova (2010)31903190FJ465125None  L74ME11D, S24H, V31I, Y99F, L101V, T112V, T124A, T125A, G134N, K136T, T206S, K215R, T218S, Y227F, L234I, S255N, D256E, S283GG
Hora (2015)DEMG09KE001DEMG09KE001KF716477None  L74M, T97AK14R, V31I, I72V, L101I, T112V, T122I, T124A, T125A, G134N, K136T, K173R, I200M, V201I, T206S, L234I, S255N, S283GG