<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype G
Gene IN
Mutation I72V
Rx II-naive
IncludeMixtures No
References 8
Patients 26
Isolates 27
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Kijak (2004)1278NG01CM.1278AY371161None   E11D, S24A, V31I, V37I, S39N, I72V, L101I, T112M, T124A, T125A, G134D, K136Q, V201I, T206S, L234I, D270H, S283GG
 1296NG01CM.1296AY371162None   E11D, S24A, V31I, V37I, S39N, I72V, L101I, T112M, T124A, T125A, G134D, I135V, K136Q, V201I, T206S, L234I, D270H, S283GG
Badreddine (2007)J11449SB_J11449DQ375267None   E11D, K14R, V31I, I72V, I89V, T206S, D232E, L234I, V249VI, S255N, D256E, S283GG
Brennan (2008)1166-161166-16EU618072None   K14R, V31I, K34R, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S283GG
 314-40314-40EU618145None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 3826-213826-21EU618166None   K14R, V31I, I72V, I84M, L101I, T112V, T124N, T125A, G134GDNS, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 44-1044-10EU618184None   K14R, M50I, I72V, T112V, T122I, T124A, T125A, G134N, V201I, A205S, T206S, L234I, S255N, D256E, R269K, D278G, S283G, R284GG
 880-29880-29EU618319None  L74IM, T97AK14R, K34R, I72V, L101I, T112V, T124G, T125A, G134D, I135V, K136T, V201I, T206S, L234I, M275V, S283GG
 988-16988-16EU618341None   K14R, V31I, I72V, T112I, T124A, T125A, G134N, I135V, K136T, G163A, V201I, T206S, T218I, L234I, S283GG
 A1649A1649EU618408None   E11D, K14R, V31I, I72V, L101I, T112I, T124N, G134N, K136T, G189R, V201I, T206S, D232E, L234I, S255N, D256E, A265VG
 A1702A1702EU618418None   K14R, V31I, I72V, I84M, L101I, T112V, T124N, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 ABB28-96ABB28-96EU618515None   K14R, V31I, I72V, L74I, P90S, A98G, L101I, T112V, T124A, K136Q, V201I, T206S, L234I, R269K, D286NG
 ABB31-96ABB31-96EU618518None   K14R, V31I, S57G, I72V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218TI, L234I, R269K, S283GG
 B506-14B506-14EU618627None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
Garrido (2009)15INT-15GU216862None   K7E, E11D, S24N, I72V, L74I, T112I, T124A, T125A, V126M, K136Q, M154ML, V201I, T206S, Q209R, L234I, S255N, D256EG
Sichtig (2009)36-E36-EFJ183533None   V31I, S57G, I72V, E96D, L101I, K111T, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234IG
 27-E27-EFJ183550None   V31I, S57G, I72V, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218TI, L234IG
 14731473FJ183583None  T97TA, G163KV31I, M50T, I72V, E96ED, Y99FL, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K173KR, V201I, T206S, L234IG
 19201920FJ183614None   I72V, Y99F, L101I, T112I, T124S, G134N, K136T, V201I, T206S, K219Q, L234I, S255N, D256EG
 44084408FJ183617None   E11D, V31I, M50I, I72V, Y99F, L101I, T112I, T124S, G134N, K136T, V201I, T206S, K219Q, L234I, S255N, D256EG
 47644764FJ183648None   E10D, E11D, K14R, A21T, A23V, V31I, S39N, D41DN, M50MI, I72V, L101I, T112I, T124A, T125A, G134N, I135IV, K136T, V201I, T206S, L234IV, S255N, D256DGG
 55155515FJ183669None  Q146QK, S147AK14R, V32I, I72V, T112V, T124A, T125A, V126M, K127R, G134N, I135V, K136T, V201I, T206S, I208M, L234IV, S255NG
Yamaguchi (2009)314-40314-40FJ389364None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
Manak (2012)53_SUPLH0153_SUPLH01JN687664None   D3E, S17N, R20K, D41N, I72V, L101I, K111R, T112I, I113V, S119P, T124A, T125A, G134D, K136Q, V201I, T206S, L234I, S283GG
Reigadas (2013)310310JX425431None   S17N, V32I, L45LQ, M50MI, I72V, L101I, T112A, T125A, G134D, K136T, Q137H, F185FY, V201I, I203M, L234I, D256E, D270N, S283G, D288NG
 319319JX425440None   S24N, V31I, L63I, I72V, L74I, K111KQ, T112MV, T124A, T125A, G134N, K136T, D167E, V201I, T206S, E212A, L234I, D256E, S283GG
 4218842188JX451944None   K14R, L28I, V31I, V32I, I72V, L101I, T112V, S123C, T124A, T125A, G134N, K136T, D167E, V201I, L234I, D256E, S283GG