<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype G
Gene IN
Mutation T206S
Rx II-naive
IncludeMixtures No
References 35
Patients 134
Isolates 138
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Carr (1998)SE6165SE6165AF061642None   K14R, S17N, V31I, L74I, L101I, K111T, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234V, S255N, D256E, S283GG
Carr (1999)JKC-VI354VI354AF076474None   E11D, K14R, R20K, V31I, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, D256E, S283GG
Oelrichs (1999)ZA_BLZA_BLAF084936None   K14R, R20K, V31I, L101I, T112I, T124A, T125A, G134S, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
Carr (2001)CM52876CM52876AF377958None   K14R, D25E, V31I, A91E, L101I, T112V, S119R, T124N, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283GG
Perez-Alvarez (2001)X558X558AF423760None   E11D, K14R, V31I, V32I, L101I, T112I, T125A, K127R, G134N, K136T, V201I, T206S, E212A, Y227F, L234I, S255N, D256E, S283GG
 X623X623AF450097None   K14R, S17N, V31I, L101I, T112I, T124S, T125A, G134N, K136T, G163T, V201I, T206S, K211R, Y227F, L234I, S255N, D256E, D270H, S283GG
 X605X605AF450096None Q148H L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 X397X397AF423756None   L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, K215N, Y227F, L234I, S255N, D256E, S283GG
 X421X421AF423757None   V32I, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 X475X475AF423758None   E11D, S17C, L101I, T112IM, T124A, T125A, G134N, K136T, K188R, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 X477X477AF423759None   S17N, Q62L, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Delgado (2002)X138X138AF450098None   E11D, K14R, V32I, L101I, T112I, T125A, G134N, K136T, V201I, T206S, E212A, Y227F, L234I, S255N, D256E, S283GG
Papathanasopoulos (2002)99ZACM499ZACM4AF411964None   E11D, S17C, V31I, L101I, T112V, I113V, T124A, T125A, G134N, T206S, N222K, L234I, S283GG
Swanson (2003)HH8793HH8793AY214079None   E11D, P30H, D41N, L101I, T112V, T124A, T125A, G134D, K136T, V201I, T206S, Y227F, L234V, S255N, D256E, S283GG
Wilbe (2003)SE9010SE9010AY352655None   E13D, K14R, S24N, V31I, L101I, T112I, T124A, T125A, V126A, K136Q, V165I, V201I, T206S, L234I, D256E, S283GG
Kijak (2004)1278NG01CM.1278AY371161None   E11D, S24A, V31I, V37I, S39N, I72V, L101I, T112M, T124A, T125A, G134D, K136Q, V201I, T206S, L234I, D270H, S283GG
 1296NG01CM.1296AY371162None   E11D, S24A, V31I, V37I, S39N, I72V, L101I, T112M, T124A, T125A, G134D, I135V, K136Q, V201I, T206S, L234I, D270H, S283GG
 0989MO01CM.0989AY371166None   K14R, S24N, V31I, M50I, L101I, T112V, S119P, T124A, T125A, G134N, K136T, V165I, V201I, T206S, D207E, T218S, S230N, L234I, D256E, A265V, S283GG
Carr (2005)01NGPL067401NGPL0674DQ168575None  E92A, T125KK14R, V31I, P90S, Y99F, L101I, T112I, G134N, K136T, V201I, T206S, L234I, S255N, D256EG
 01NGPL066901NGPL0669DQ168576None   K14R, S24N, L101I, T112V, T124S, T125A, G134S, K136T, V201I, T206S, L234I, D256E, S283GG
 01NGPL076001NGPL0760DQ168579None   K14R, V31I, M50V, L101I, T112V, T124N, G134N, K136T, I162V, V201I, T206S, I208L, L234I, S255N, D256E, S283GG
Harris (2005)9196_019196_01AY882421None  L74LM, T97AE11D, L101I, T112I, T122I, T124N, S195T, T206S, Y227F, L234I, S255N, D256E, S283GG
Holzmayer (2005)96CMABB5596CMABB55AY772535None   K14R, V31I, L45V, M50I, T124G, T125A, G134N, K136T, Q164K, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Toni (2005)01IC_1739501_17395AJ866554None   K14R, V32I, S39N, L45Q, L101I, T112V, I113V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, D270H, S283GG
Carr (2006)2931HA2931HADQ826727None   E10D, V31I, L101V, T112V, S119P, T122I, T124A, T125A, G134D, D167E, V201I, T206S, I208M, T218I, L234I, D256E, V281M, S283GG
Njai (2006)MP80197CM.801AM279373None   E11D, V31I, Y99F, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234IG
 MP141799CM.1417AM279377None  L74MK14R, V31I, L101I, T112I, T122TI, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234I, L242LHG
 MP141699CM.1416AM279386None  L74MK14R, V32I, M50I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234IG
Badreddine (2007)J11226SB_J11226DQ375249None   K14R, S17SN, A23V, V31I, V32I, L101I, T112V, S119P, T124A, T125A, G134N, K136N, V201I, T206S, T218S, K219N, N222K, S230N, L234I, S283GG
 J11230SB_J11230DQ375252None   K14R, A23V, V32I, L101I, T112V, S119P, T124A, T125A, G134N, K136N, V201I, T206S, T218S, L234I, S283GG
 J11238SB_J11238DQ375256None   E11D, K14R, V32I, K42KR, L101I, T112V, T124N, K136T, K173R, V201I, T206S, I208M, T218I, N222H, D229E, L234I, S255N, D256E, R269K, S283GG
 J11407SB_J11407DQ375263None  T97AK14R, V31I, L101I, T112V, T124N, G134N, K136T, V201I, T206S, L234I, D256E, S283GG
 J11449SB_J11449DQ375267None   E11D, K14R, V31I, I72V, I89V, T206S, D232E, L234I, V249VI, S255N, D256E, S283GG
 J11454SB_J11454DQ375270None   K14R, V32I, S39C, L101I, T112V, S119P, T122I, T124A, T125A, D167E, V201I, T206S, T218I, L234I, S283GG
 J11205SB_J11205DQ848150None   S17N, L28I, I72T, L101V, T112V, S119P, T122I, T124A, T125A, V126M, G134D, D167E, V201I, T206S, T218I, L234I, D256E, S283GG
Sierra (2007)R77R77AY586544None   E11D, K14R, S24N, V31I, T112V, S119P, T122I, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 Cu74Cu74AY586547None   K14R, V31I, V32I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, D279A, S283GG
 Cu87Cu87AY586549None   E11D, K14R, S17T, A23V, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 CB378CB378AY900574None   K14R, V31I, L101I, T112V, S119P, T122I, T124A, T125A, G134D, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283G, D288NG
 CB471CB471AY900575None   K14R, V31I, S57N, L101I, T112V, S119P, T124A, T125A, G134S, K136T, V201I, A205S, T206S, L234I, S255N, D256E, S283GG
 CB134CB134DQ020274None   K14R, S24N, V31I, L101I, T112V, T122I, T124A, T125A, G134N, K136T, V201I, A205S, T206S, L234I, S255N, D256E, S283GG
Brennan (2008)1010-331010-33EU618062None   K14R, S17N, M50I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V165I, V201I, T206S, L234I, D256E, S283GG
 1166-161166-16EU618072None   K14R, V31I, K34R, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S283GG
 144-26144-26EU618088None   K14R, R20K, V31I, M50T, L101I, T112V, T124A, T125V, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 172-28172-28EU618101None   E11D, L45Q, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S283GG
 18-918-9EU618109None  L74MK14R, V31I, L101I, K111T, T112TI, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 235-4235-4EU618121None   K14R, V31I, L101I, T112I, T124A, T125A, G134D, K136T, D167E, V201I, T206S, L234I, D270G, S283GG
 252-14252-14EU618127None   E11ED, S17SN, V31I, L74I, L101I, T112V, T124A, T125A, G134N, K136Q, V201I, T206S, L234I, S283GG
 262-26262-26EU618132None   E11D, K14R, S24N, T112I, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S283GG
 314-40314-40EU618145None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 37-237-2EU618159None   S17N, G106A, T112V, T124N, G134N, K136T, Q137H, V201I, T206S, L234I, S255N, D256E, S283GG
 3826-213826-21EU618166None   K14R, V31I, I72V, I84M, L101I, T112V, T124N, T125A, G134GDNS, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 44-1044-10EU618184None   K14R, M50I, I72V, T112V, T122I, T124A, T125A, G134N, V201I, A205S, T206S, L234I, S255N, D256E, R269K, D278G, S283G, R284GG
 515-28515-28EU618222None   K14R, R20K, V31VI, L101I, T112V, T124N, T125A, G134S, K136T, V201I, T206S, I208L, L234I, S255N, D256E, R284G, D288NG
 516-15516-15EU618223None   K14R, S24SG, L74I, A91E, L101I, T112V, S119R, T124A, T125A, G134D, I135V, V201I, T206S, Y227F, L234I, A265V, S283GG
 524-24524-24EU618228None   E11D, K14R, A21T, A23V, V31I, L101I, T112V, T124A, G134N, K136Q, V165I, V201I, T206S, E212A, L234I, D256E, I268L, S283GG
 5244-255244-25EU618229None   E11D, K14KR, S17T, V31I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, D270DE, S283GG
 746-25746-25EU618292None  T97AE11D, K14R, S24N, V31I, L101I, T112V, T124N, T125A, G134N, K136T, G163A, V201I, T206S, I217V, L234I, S255N, D256E, S283GG
 88-588-5EU618318None   R20RK, V31I, E96D, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, R269K, S283GG
 880-29880-29EU618319None  L74IM, T97AK14R, K34R, I72V, L101I, T112V, T124G, T125A, G134D, I135V, K136T, V201I, T206S, L234I, M275V, S283GG
 988-16988-16EU618341None   K14R, V31I, I72V, T112I, T124A, T125A, G134N, I135V, K136T, G163A, V201I, T206S, T218I, L234I, S283GG
 A1649A1649EU618408None   E11D, K14R, V31I, I72V, L101I, T112I, T124N, G134N, K136T, G189R, V201I, T206S, D232E, L234I, S255N, D256E, A265VG
 A1653A1653EU618409None   K14R, V31I, S57G, E96D, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234V, R269K, S283GG
 A1702A1702EU618418None   K14R, V31I, I72V, I84M, L101I, T112V, T124N, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 A1776A1776EU618443None   K14R, L101I, T112V, T124N, G134N, K136T, V201I, T206S, I208L, E212A, L234I, S255N, S283GG
 AB811AB811EU618489None   S17N, V31I, M50I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I208L, L234I, S255N, D256E, S283GG
 ABB28-96ABB28-96EU618515None   K14R, V31I, I72V, L74I, P90S, A98G, L101I, T112V, T124A, K136Q, V201I, T206S, L234I, R269K, D286NG
 ABB30-96ABB30-96EU618517None   K14R, V32I, M50I, Y99F, L101I, T112V, T124N, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 ABB31-96ABB31-96EU618518None   K14R, V31I, S57G, I72V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218TI, L234I, R269K, S283GG
 ABB70-96ABB70-96EU618555None   K14R, V31I, L101I, T112V, I113V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218M, L234I, S255N, D256E, I268L, S283GG
 ABB71-96ABB71-96EU618556None   K14R, A21T, S24N, V31I, L45V, M50I, I84M, L101I, T112V, T124A, G134N, K136T, I182V, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 ABB124-98ABB124-98EU618596None   K14R, M50I, Y99F, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 ABB142-98ABB142-98EU618599None   E10D, K14KR, V31I, L101I, T112A, T124A, T125A, G134N, K136T, V165I, V201I, T206S, E212A, K219N, L234I, D256E, S283GG
 ABB144-98ABB144-98EU618600None   E11D, S24N, P30S, V31I, M50I, I60IMV, L101I, T112V, T124S, T125A, G134N, K136T, V165I, D167DE, V201I, T206S, L234I, D256E, S283GG
 B506-14B506-14EU618627None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
Yamaguchi (2008)J11235J11235EU697913None   E11D, V32I, K42R, Y99F, L101I, T112V, T124N, G134N, K136T, K173R, V201I, T206S, T218I, D229E, L234I, S255N, D256E, R269RK, S283GG
Eshleman (2009)ABB30-96ABB30-96FJ480277None   K14R, V32VI, M50MI, Y99YF, L101I, T112V, T124N, G134N, K136T, V201I, T206S, K211KR, L234I, S255N, D256E, S283GG
 ABB55-96ABB55-96FJ480284None   K14R, V31I, L45V, M50I, L101LI, T124G, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 ABB125-98ABB125-98FJ480306None  L74MK14R, K34R, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, M275V, S283GG
 ABB142-98ABB142-98FJ480307None   E10D, K14KR, V31I, L101I, T112A, T124A, T125A, G134N, K136T, V165I, V201I, T206S, E212A, K219N, L234I, D256E, S283GG
Garrido (2009)15INT-15GU216862None   K7E, E11D, S24N, I72V, L74I, T112I, T124A, T125A, V126M, K136Q, M154ML, V201I, T206S, Q209R, L234I, S255N, D256EG
 31INT-31GU216878None   E11D, K14R, S17T, M50I, T112I, T124A, T125A, G134N, K136T, Q137QH, V201I, T206S, Y227F, L234I, S255N, D256E, D279DN, R284RTG
 37INT-37GU216884None   K14R, V31I, S57N, L101I, K111R, T112V, T124N, G134N, K136T, I161L, V201I, T206S, L234I, S255N, D256EG
 41INT-41GU216888None   V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, K215N, L234I, R269KG
 45INT-45GU216892None   L45I, I60V, L74I, T112V, T124A, T125A, I135V, K136R, G193R, V201I, T206S, I208L, L234IG
 50INT-50GU216897None   E11D, K34R, L101I, T112I, T124A, T125A, G134N, I135V, K136T, D167E, V201I, T206S, L234IG
 72INT-72GU216919None   D6DG, E11D, K14R, S17T, M50I, T112I, T124A, T125A, G134N, K136T, Q137H, V201I, T206S, Y227F, L234I, S255N, D256EG
 84INT-84GU216931None   K14R, R20K, V31VI, L101I, K111KR, T112V, T124A, T125A, G134N, I135V, K136T, G163V, V201I, T206S, T218S, L234I, D256EG
 99INT-99GU216946None   V31I, T112V, S119P, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234IG
 143INT-143GU216990None   E11D, K14R, S24N, D25E, V31I, V32VI, L101I, T112V, S119P, T122TI, T124N, T125A, G134N, I135V, K136T, D167DE, V201I, A205S, T206S, L234I, S255N, D256EG
 191INT-191GU217038None   K14R, R20K, T112V, T124A, T125A, G134D, I135V, V201I, T206S, L234IG
 195INT-195GU217042None   E11D, S17T, V32I, V37VI, M50I, E96D, L101I, T112IV, S119R, T124TA, T125A, G134DN, K136T, V165I, V201I, T206SG
 203INT-203GU217050None   E11D, S17T, V32I, M50I, L101I, S119G, T122I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, G277GVG
 244INT-244GU217091None   K14R, V31I, L101I, T112I, T124N, G134N, K136T, D167E, V201I, T206S, Y227F, L234I, S255N, D256E, K264KN, K266KTG
Kousiappa (2009)CY063CY063FJ388908None   E11Q, K14R, L101I, T112V, T124A, T125A, K136T, D167E, V201I, T206S, L234I, S255N, D256E, S283GG
Sichtig (2009)36-E36-EFJ183533None   V31I, S57G, I72V, E96D, L101I, K111T, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234IG
 27-E27-EFJ183550None   V31I, S57G, I72V, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218TI, L234IG
 58-E58-EFJ183553None   D25E, V31I, D41N, L101I, T112I, T124A, T125A, I135V, K136T, F181Y, V201I, T206S, L234IG
 59-E59-EFJ183554None   V32I, M50T, I84IL, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234IG
 14731473FJ183583None  T97TA, G163KV31I, M50T, I72V, E96ED, Y99FL, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K173KR, V201I, T206S, L234IG
 883883FJ183613None   L101I, T124S, T125A, K136T, G163A, G193V, V201I, T206S, L234I, D256EG
 19201920FJ183614None   I72V, Y99F, L101I, T112I, T124S, G134N, K136T, V201I, T206S, K219Q, L234I, S255N, D256EG
 44084408FJ183617None   E11D, V31I, M50I, I72V, Y99F, L101I, T112I, T124S, G134N, K136T, V201I, T206S, K219Q, L234I, S255N, D256EG
 19-E19-EFJ183638None   V31VI, A91AE, L101I, T112TAIV, T124N, T125A, G134N, I135V, K136T, V201I, T206S, T218TI, L234IG
 52-E52-EFJ183639None   V31VA, Y99H, L101V, T112V, H114HR, S119P, T124A, T125A, G134D, I135V, F181L, V201I, T206S, I208L, T218I, L234I, D256EG
 53-E53-EFJ183640None   K34KR, S39SC, L101I, T112V, T124N, T125A, G134N, K136T, V201I, T206S, Y227F, L234V, S255N, D256EG
 47644764FJ183648None   E10D, E11D, K14R, A21T, A23V, V31I, S39N, D41DN, M50MI, I72V, L101I, T112I, T124A, T125A, G134N, I135IV, K136T, V201I, T206S, L234IV, S255N, D256DGG
 55155515FJ183669None  Q146QK, S147AK14R, V32I, I72V, T112V, T124A, T125A, V126M, K127R, G134N, I135V, K136T, V201I, T206S, I208M, L234IV, S255NG
 32423242FJ183707None   V31I, M50I, S57G, L101I, T112I, T124H, T125A, G134N, I135V, K136T, V201I, T206S, L234IG
Wittkop (2009)44_M0GU358382None   K14R, V31I, Y99F, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E, S283GG
Yamaguchi (2009)314-40314-40FJ389364None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 515-28515-28FJ389365None   K14R, R20K, L101I, T112V, T124N, T125A, G134S, K136T, V201I, T206S, I208L, L234I, S255N, D256E, R284G, D288NG
Avi (2010)N61N61GQ926806None   E11D, S24N, V31I, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T206S, T218I, L234V, D256EG
Fish (2010)P5209ZAP52GQ872506None   S17N, K34R, L101I, T112V, T124A, T125A, G134D, K136T, E157Q, K160Q, D167E, V201I, T206S, L234I, D270E, S283GG
Bartolo (2011)00PTHDE1000PTHDE10GU230137None   L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283G, Q285PG
 00PTHSM500PTHSM5GU230138None   K14R, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, M275V, S283G, Q285PG
 98PTHEM10398PTHEM103GU230139None   E11D, L101I, T112I, T124A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Brenner (2011)74627462HQ207757None   E13D, K14R, V31I, M50I, L101I, T112IV, S119T, T124G, T125A, G134S, V201I, T206S, I220L, Q221S, L234I, A265AV, S283GG
Garrido (2012)BAA295947BAA295947JQ716860None   K14R, L101I, T112I, T124A, T125A, G134N, K136T, D167E, V201I, T206S, Q221H, D232E, L234I, S255N, D256E, S283GG
Monleau (2012)SK4079SK4079JQ250517None   K14R, V31I, L101I, K111Q, T112V, I113IL, S119P, T122I, T124A, T125A, D167E, V201I, T206S, L234I, I251IL, D256E, A265V, S283GG
 SK1033SK1033JQ250523None   E11ED, K14R, V31I, L101I, T124A, T125A, G134D, K136T, R187RK, G193GEKR, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E, S283DGG
 SK4073SK4073JQ250530None  T97AK14R, S24N, I72IV, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218S, L234I, S255N, D256DE, S283GG
 SK1009SK1009JQ250532None   K14R, S17N, V31I, M50MI, L101I, T112I, T124A, T125A, G134N, K136T, I141IV, K156R, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 SK3036SK3036JQ250538None   E13ED, K14R, S24HN, V31I, A91AS, E96D, L101I, K103R, T112V, S119R, T124A, T125A, G134N, K136T, V165VI, V201I, T206S, I208L, T218TS, Y227F, S230N, L234I, S255N, D256E, S283GG
Oliveira (2012)GA57GA57JQ670824None   K14R, V31I, L74I, G106A, T112V, S119P, T125A, K136Q, D167E, V201I, T206S, D207E, L234I, S255N, D256E, C280Y, S283GG
Parczewski (2012)235_1235_1KC409150None   K14KR, L28LI, P30S, L101I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E, S283GG
Reigadas (2013)319319JX425440None   S24N, V31I, L63I, I72V, L74I, K111KQ, T112MV, T124A, T125A, G134N, K136T, D167E, V201I, T206S, E212A, L234I, D256E, S283GG
 322322JX425443None   E11D, K14R, V32I, L101I, T112I, T122I, T125A, G134N, K136T, V201I, T206S, K211R, E212I, Y227F, L234I, S255N, D256E, S283GG
 323323JX425446None  L74LIME11D, K14R, V32I, L101I, T112I, T124TA, T125A, G134N, K136T, V201I, T206S, K211KR, E212AT, Y227F, L234I, S255N, D256E, S283GG
 490490JX425823None   K14R, S24N, L74I, T112I, T124N, T125A, G134N, K136T, V201I, T206S, L213Q, D232N, L234I, S255N, D256E, S283G, R284G, D286NG
 750750JX425876None   E11D, K14R, A21T, V32I, S39C, L101I, T112TIM, T124A, T125A, G134N, K136T, E157EQ, D167DE, V201I, I203M, T206S, Y227F, L234I, S255N, D256E, S283GG
 751751JX425877None  L68VE11D, E35EK, K71KR, L74LV, L101I, T112R, S119P, T124A, T125A, G134D, K136T, K188R, V201I, T206S, L234I, S255N, D256E, D279DG, S283GG
 754754JX425880None   S17N, R20K, L101I, T112V, T124N, G134N, K136T, K173R, V201I, T206S, L234I, S255N, D256E, S283GG
 757757JX425883None   E11D, E13D, S24N, V31I, L45V, M50I, G59E, I84M, L101I, T112A, T124A, G134N, K136T, G163A, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 758758JX425884None   G4GS, K14R, S17C, K34KR, M50I, I72IV, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I220IL, L234I, S255N, M275MV, D278DG, S283GG
 101010101010JX451923None  L68VE11D, R20K, V31I, L101I, K111N, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 4212642126JX451929None   V31I, L101I, T112V, T125V, G134D, K136Q, G163E, V201I, T206S, I208L, T210I, T218I, F223Y, L234V, R269K, S283SG, D286N, D288NG
 4126141261JX451934None   K14R, V31I, S39SN, K42R, I84M, T112V, T124N, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, R269K, S283GG

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