<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype G
Gene IN
Mutation V201I
Rx II-naive
IncludeMixtures No
References 35
Patients 166
Isolates 170
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Carr (1998)SE6165SE6165AF061642None   K14R, S17N, V31I, L74I, L101I, K111T, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234V, S255N, D256E, S283GG
 HH8793HH8793AF061641None   E11D, P30H, V31I, D41H, L101I, T112V, T124A, T125A, W131R, G134D, K136T, A196S, V201I, T206S, K219Q, Y227F, L234V, S255N, D256E, S283GG
Oelrichs (1999)ZA_BLZA_BLAF084936None   K14R, R20K, V31I, L101I, T112I, T124A, T125A, G134S, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
Perez-Alvarez (2001)X558X558AF423760None   E11D, K14R, V31I, V32I, L101I, T112I, T125A, K127R, G134N, K136T, V201I, T206S, E212A, Y227F, L234I, S255N, D256E, S283GG
 X623X623AF450097None   K14R, S17N, V31I, L101I, T112I, T124S, T125A, G134N, K136T, G163T, V201I, T206S, K211R, Y227F, L234I, S255N, D256E, D270H, S283GG
 X605X605AF450096None Q148H L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Wilbe (2002)CM-184996CM-1849AF460972None   E11D, K14R, A21T, M50T, L101I, T112V, T124A, T125A, G134N, K136T, D167E, V201I, I208L, T218I, L234I, D256E, S283GG
 CM-416496CM-4164AF460974None   D6E, E10D, R20K, M50I, L101I, T112V, S119G, T122I, T124A, T125A, G134N, K136T, V201I, T218I, L234I, D256E, S283GG
Swanson (2003)HH8793HH8793AY214079None   E11D, P30H, D41N, L101I, T112V, T124A, T125A, G134D, K136T, V201I, T206S, Y227F, L234V, S255N, D256E, S283GG
Carr (2005)01NGPL067401NGPL0674DQ168575None  E92A, T125KK14R, V31I, P90S, Y99F, L101I, T112I, G134N, K136T, V201I, T206S, L234I, S255N, D256EG
 01NGPL066901NGPL0669DQ168576None   K14R, S24N, L101I, T112V, T124S, T125A, G134S, K136T, V201I, T206S, L234I, D256E, S283GG
 01NGPL076001NGPL0760DQ168579None   K14R, V31I, M50V, L101I, T112V, T124N, G134N, K136T, I162V, V201I, T206S, I208L, L234I, S255N, D256E, S283GG
Holzmayer (2005)96CMABB5596CMABB55AY772535None   K14R, V31I, L45V, M50I, T124G, T125A, G134N, K136T, Q164K, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Njai (2006)MP80197CM.801AM279373None   E11D, V31I, Y99F, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234IG
 MP141799CM.1417AM279377None  L74MK14R, V31I, L101I, T112I, T122TI, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234I, L242LHG
 MP141699CM.1416AM279386None  L74MK14R, V32I, M50I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, I203M, T206S, Y227F, L234IG
 MP103398CM.1033AM279392None   V31I, Y99L, L101I, T112M, T124A, T125A, G134N, K136T, V201I, L234IG
Badreddine (2007)J11238SB_J11238DQ375256None   E11D, K14R, V32I, K42KR, L101I, T112V, T124N, K136T, K173R, V201I, T206S, I208M, T218I, N222H, D229E, L234I, S255N, D256E, R269K, S283GG
 J11407SB_J11407DQ375263None  T97AK14R, V31I, L101I, T112V, T124N, G134N, K136T, V201I, T206S, L234I, D256E, S283GG
Luk (2007)CM-632-2804-632-28DQ845387None   D6E, K14R, L101I, T112V, T124A, T125A, K136T, H171Y, K188R, V201I, I208L, L234I, A265V, S283GG
 CM-A139402CM-A1394DQ845388None   K14R, T112V, T124A, T125A, G134N, K136T, G163T, V201I, T206S, L234I, S283GG
Powell (2007)CMNYU83000CMNYU830EF087994None   E11D, K14R, V31I, L74I, P90S, T112V, T124A, T125A, G134D, K136Q, V201I, T206S, L234I, D270N, S283GG
Brennan (2008)144-26144-26EU618088None   K14R, R20K, V31I, M50T, L101I, T112V, T124A, T125V, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 148-04148-04EU618091None   K14R, V31I, L101I, T112I, T124A, T125A, G134N, K136T, V165I, G193E, V201I, I208L, T218I, L234I, D256E, V260VI, D286NG
 18-918-9EU618109None  L74MK14R, V31I, L101I, K111T, T112TI, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 314-40314-40EU618145None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 37-237-2EU618159None   S17N, G106A, T112V, T124N, G134N, K136T, Q137H, V201I, T206S, L234I, S255N, D256E, S283GG
 3826-213826-21EU618166None   K14R, V31I, I72V, I84M, L101I, T112V, T124N, T125A, G134GDNS, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 44-1044-10EU618184None   K14R, M50I, I72V, T112V, T122I, T124A, T125A, G134N, V201I, A205S, T206S, L234I, S255N, D256E, R269K, D278G, S283G, R284GG
 447-8447-8EU618191None   K14R, K34R, L74I, L101I, T112V, T124A, T125A, G134D, K136Q, V201I, T206S, L234I, S255N, D270N, S283GG
 515-28515-28EU618222None   K14R, R20K, V31VI, L101I, T112V, T124N, T125A, G134S, K136T, V201I, T206S, I208L, L234I, S255N, D256E, R284G, D288NG
 5244-255244-25EU618229None   E11D, K14KR, S17T, V31I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, D270DE, S283GG
 746-25746-25EU618292None  T97AE11D, K14R, S24N, V31I, L101I, T112V, T124N, T125A, G134N, K136T, G163A, V201I, T206S, I217V, L234I, S255N, D256E, S283GG
 A1649A1649EU618408None   E11D, K14R, V31I, I72V, L101I, T112I, T124N, G134N, K136T, G189R, V201I, T206S, D232E, L234I, S255N, D256E, A265VG
 A1702A1702EU618418None   K14R, V31I, I72V, I84M, L101I, T112V, T124N, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 A1776A1776EU618443None   K14R, L101I, T112V, T124N, G134N, K136T, V201I, T206S, I208L, E212A, L234I, S255N, S283GG
 ABB30-96ABB30-96EU618517None   K14R, V32I, M50I, Y99F, L101I, T112V, T124N, G134N, K136T, V201I, T206S, L234I, S255N, D256E, S283GG
 ABB71-96ABB71-96EU618556None   K14R, A21T, S24N, V31I, L45V, M50I, I84M, L101I, T112V, T124A, G134N, K136T, I182V, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 ABB124-98ABB124-98EU618596None   K14R, M50I, Y99F, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 B506-14B506-14EU618627None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
Van Laethem (2008)AR03-754AR03-754EU882763None  V151IK14R, L101I, T124A, T125A, G134GDNS, K136T, D167DE, H171Q, V201I, I208L, K211KR, L234I, D256E, S283GG
 AR06-225AR06-225EU882764None  V151IK7Q, E11D, L101I, S119SAGT, T122I, T124A, T125TA, G134N, D167E, V201I, I208L, L234I, S283GG
 AR06-009AR06-009EU882797None   K14R, S17N, V31I, L74I, L101I, T112V, I113L, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, S255N, D256EG
 AR06-1186AR06-1186EU882798None   E11D, K14R, S24N, V31I, L101V, T112V, T124N, T125A, G134N, K136RT, G163E, V201I, T206S, T218A, Y227F, L234I, S255N, D256E, S283GG
 P00-530P00-530EU882765None   K14R, L101V, T112V, S119P, T124A, T125A, G134N, K136T, V201I, I208L, T218I, L234I, D256E, S283SGG
Yamaguchi (2008)J11235J11235EU697913None   E11D, V32I, K42R, Y99F, L101I, T112V, T124N, G134N, K136T, K173R, V201I, T206S, T218I, D229E, L234I, S255N, D256E, R269RK, S283GG
Eshleman (2009)ABB30-96ABB30-96FJ480277None   K14R, V32VI, M50MI, Y99YF, L101I, T112V, T124N, G134N, K136T, V201I, T206S, K211KR, L234I, S255N, D256E, S283GG
 ABB55-96ABB55-96FJ480284None   K14R, V31I, L45V, M50I, L101LI, T124G, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 ABB125-98ABB125-98FJ480306None  L74MK14R, K34R, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, M275V, S283GG
Garrido (2009)31INT-31GU216878None   E11D, K14R, S17T, M50I, T112I, T124A, T125A, G134N, K136T, Q137QH, V201I, T206S, Y227F, L234I, S255N, D256E, D279DN, R284RTG
 37INT-37GU216884None   K14R, V31I, S57N, L101I, K111R, T112V, T124N, G134N, K136T, I161L, V201I, T206S, L234I, S255N, D256EG
 45INT-45GU216892None   L45I, I60V, L74I, T112V, T124A, T125A, I135V, K136R, G193R, V201I, T206S, I208L, L234IG
 72INT-72GU216919None   D6DG, E11D, K14R, S17T, M50I, T112I, T124A, T125A, G134N, K136T, Q137H, V201I, T206S, Y227F, L234I, S255N, D256EG
 143INT-143GU216990None   E11D, K14R, S24N, D25E, V31I, V32VI, L101I, T112V, S119P, T122TI, T124N, T125A, G134N, I135V, K136T, D167DE, V201I, A205S, T206S, L234I, S255N, D256EG
 195INT-195GU217042None   E11D, S17T, V32I, V37VI, M50I, E96D, L101I, T112IV, S119R, T124TA, T125A, G134DN, K136T, V165I, V201I, T206SG
 203INT-203GU217050None   E11D, S17T, V32I, M50I, L101I, S119G, T122I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, G277GVG
 244INT-244GU217091None   K14R, V31I, L101I, T112I, T124N, G134N, K136T, D167E, V201I, T206S, Y227F, L234I, S255N, D256E, K264KN, K266KTG
Sichtig (2009)14841484FJ183596None  V151IL101I, T112V, T124A, T125A, G134N, K136T, D167E, V201I, I208L, T218I, L234I, D256EG
 883883FJ183613None   L101I, T124S, T125A, K136T, G163A, G193V, V201I, T206S, L234I, D256EG
 19201920FJ183614None   I72V, Y99F, L101I, T112I, T124S, G134N, K136T, V201I, T206S, K219Q, L234I, S255N, D256EG
 44084408FJ183617None   E11D, V31I, M50I, I72V, Y99F, L101I, T112I, T124S, G134N, K136T, V201I, T206S, K219Q, L234I, S255N, D256EG
 19-E19-EFJ183638None   V31VI, A91AE, L101I, T112TAIV, T124N, T125A, G134N, I135V, K136T, V201I, T206S, T218TI, L234IG
 47644764FJ183648None   E10D, E11D, K14R, A21T, A23V, V31I, S39N, D41DN, M50MI, I72V, L101I, T112I, T124A, T125A, G134N, I135IV, K136T, V201I, T206S, L234IV, S255N, D256DGG
 2657rc2657rcFJ183690None   K14R, V31I, L63V, L74I, T112V, T124S, T125A, G134N, K136T, V201I, K211R, Y227F, L234I, S255N, D256EG
Wittkop (2009)44_M0GU358382None   K14R, V31I, Y99F, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E, S283GG
Yamaguchi (2009)314-40314-40FJ389364None   K14R, V31I, I72V, I84V, T112V, T124A, T125A, G134N, K136T, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 515-28515-28FJ389365None   K14R, R20K, L101I, T112V, T124N, T125A, G134S, K136T, V201I, T206S, I208L, L234I, S255N, D256E, R284G, D288NG
Cuevas (2010)ES_X2456-2ES_X2456-2FJ670526None   E11Q, K14R, M50I, I72V, L101I, T112V, S119P, T122I, T124A, T125A, G134D, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, D270H, S283GG
 ES_P962ES_P962EU786670None   S24N, V31I, Y99F, L101I, T112M, S119G, T124N, T125A, G134N, K136T, K173R, V201I, T206S, T218I, L234I, D256E, S283GG
 ES_P1981-2ES_P1981-2FJ670530None   K14R, S17N, M50I, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283G, E287KG
 X2634-2X2634-2GU362882None   K14R, S17N, L101I, T112I, T124A, G134N, K136T, G163M, K173R, V201I, T206S, I208L, L234I, S255N, D256E, S283GG
 ES_X1870ES_X1870FJ670522None   K14R, S17N, L28I, L101I, S119T, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Fish (2010)P5209ZAP52GQ872506None   S17N, K34R, L101I, T112V, T124A, T125A, G134D, K136T, E157Q, K160Q, D167E, V201I, T206S, L234I, D270E, S283GG
Gafarova (2010)31953195FJ465128None   K14R, S24N, V31I, M50I, L74I, L101I, T112V, T124N, T125A, G134N, G163E, H171Q, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 31883188FJ465124None  G140RE11D, K14R, S24N, V31I, G47E, M50I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, R269K, S283GG
 30333033FJ465121None   K14R, S24N, V31I, K42R, L101I, K103R, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30313031FJ465120None   E11D, V31I, M50I, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30293029FJ465118None   E11D, S24N, V31I, M50I, L101I, T112V, T122I, T124A, T125A, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30283028FJ465117None   E11D, K14R, S24N, V31I, M50I, L101I, T112V, S119G, T122I, T124N, T125A, G134N, S153A, G163E, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30273027FJ465116None   E11D, S24N, V31I, M50I, L101I, T112V, T122I, T124A, T125A, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30253025FJ465115None   E11D, S24N, V31I, M50I, L101I, T112V, T124N, T125A, G134N, I135V, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30243024FJ465114None   E11D, K14R, S24H, V31I, V32I, S39C, L45V, M50I, L101I, T112V, S119G, T124N, T125A, G134D, V201I, T206S, T218S, Y227F, L234I, S255N, S283GG
 30223022FJ465112None   E11D, K14R, S24N, V31I, M50I, L101I, T112V, S119G, T122I, T124A, T125A, G134N, G163A, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30213021FJ465111None   E11D, K14R, V31I, M50I, L101I, T112I, T124A, T125A, G134N, K136T, G163A, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, A276G, S283GG
 30203020FJ465110None   K14R, S24H, V31I, M50I, L101I, T112V, T125V, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30183018FJ465108None   E11D, K14R, S24N, V31I, M50I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 30173017FJ465107None   E11D, K14R, S24N, V31I, M50I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 29842984FJ465105None   K14R, S24N, V31I, L101I, K103R, T112V, T122I, T124A, T125A, G134N, K136T, V201I, T206S, T218S, L234I, S255N, D256E, S283GG
 29832983FJ465104None   E11D, E13D, S24N, P30S, M50I, I60M, L101I, T112V, T124A, T125A, G134D, I135V, K136T, V201I, T206S, T218S, Y227F, L234I, D253H, S255N, D256E, M275V, S283GG
 29812981FJ465103None   K14R, S24N, M50L, L101I, T112I, T124Q, T125V, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 29792979FJ465102None   I5L, K7T, E11D, K14R, S24N, V31I, V32I, K42R, M50L, L101I, T112I, T124Q, T125V, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 29772977FJ465100None   K14R, S24N, V31I, M50I, L101I, K111T, T112I, T124Q, T125V, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 29762976FJ465099None   E11D, K14R, S24N, L101I, T112V, T124A, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 29742974FJ465098None   E11D, K14R, S24N, V32I, K42R, M50I, L101I, T112I, T124Q, T125A, G134N, I135V, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 29732973FJ465097None   E11D, K14R, S24H, V32I, L74I, Y99F, L101V, T112V, T124A, T125A, G134N, K136T, V165I, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 29712971FJ465096None   E11D, R20K, S24N, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, I203V, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 33023302FJ473405None   E11D, K14R, S17N, S24N, L28I, P30A, L101I, T112I, T122I, T124A, T125A, K127R, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, P238L, S255N, D256E, S283GG
 33003300FJ473404None  G140R, G163RK14R, S24N, V31I, K42R, G47E, M50I, L101I, T112V, T124A, T125A, G134N, K136T, R166K, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, R269K, S283GG
 32943294FJ473403None   E11D, S24N, D25E, V31I, M50I, L101I, T112V, G134N, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, D270E, S283GG
 32893289FJ473402None   E11D, K14R, S24N, V31I, A49T, M50I, L101I, K111R, T112V, G134N, V165I, G193E, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283G, D288NG
 32803280FJ473401None   E11D, K14R, S24H, V31I, K42R, M50I, L101I, T112V, T124A, T125A, G134D, I135V, K136T, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 32743274FJ473400None   E11D, K14R, S24N, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218S, N222K, L234I, S255N, D256E, M275V, S283GG
 32723272FJ473399None   E11D, K14R, S24N, V31I, M50I, L101I, T112V, S119G, T122I, T124N, T125A, G134N, S153A, G163E, V201I, T206S, T218S, Y227F, L234I, S255N, D256E, S283GG
 32713271FJ473398None   E11D, K14R, S24N, V31I, V32I, S39C, L45V, M50I, K71R, L101I, T112V, S119G, T124N, T125A, G134D, V201I, T206S, T218S, Y227F, L234I, S255NG
Bartolo (2011)00PTHDE1000PTHDE10GU230137None   L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283G, Q285PG
 00PTHSM500PTHSM5GU230138None   K14R, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, M275V, S283G, Q285PG
 98PTHEM10398PTHEM103GU230139None   E11D, L101I, T112I, T124A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Charurat (2012)09NG.SC3109NG.SC31JN248591None   K14R, V31I, Y99F, L101I, G106A, T124S, G134N, K136T, V201I, T206S, E212Q, L234I, D256E, S283G, R284GG
 09NG.SC2109NG.SC21JN248584None   E11D, K14R, V31I, L74I, Y99F, L101I, T112V, I113V, S119P, T124A, T125A, G134D, K136T, V201I, T206S, I208L, K211R, T218I, L234I, S255N, D256E, A265T, R269K, D278G, S283GG
 09NG.SC2609NG.SC26JN248586None   S17N, V31I, L101I, T112I, T124N, G134N, K136T, V201I, T206S, I208L, L234I, S255N, D256E, S283G, D286AG
 09NG.SC6209NG.SC62JN248593None   E11D, K14R, V31I, A91T, L101I, T112V, T124N, G134N, K136T, E157K, A169T, V201I, T206S, L234I, D256E, S283GG
 08NG.SC1308NG.SC13JN248582None   K14R, K34R, L74I, G82S, L101I, T124N, G134N, K136T, V201I, T206S, L234I, D256E, M275V, S283G, D286AG
Monleau (2012)SK1033SK1033JQ250523None   E11ED, K14R, V31I, L101I, T124A, T125A, G134D, K136T, R187RK, G193GEKR, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E, S283DGG
 SK3015SK3015JQ250524None   K14R, R20K, L74I, L101I, T112TI, T124A, T125A, G134D, K136Q, V201I, I208IL, K211KRT, R224RW, L234I, S255N, D256E, D279G, S283GG
 SK1009SK1009JQ250532None   K14R, S17N, V31I, M50MI, L101I, T112I, T124A, T125A, G134N, K136T, I141IV, K156R, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 SK3036SK3036JQ250538None   E13ED, K14R, S24HN, V31I, A91AS, E96D, L101I, K103R, T112V, S119R, T124A, T125A, G134N, K136T, V165VI, V201I, T206S, I208L, T218TS, Y227F, S230N, L234I, S255N, D256E, S283GG
Oliveira (2012)GA57GA57JQ670824None   K14R, V31I, L74I, G106A, T112V, S119P, T125A, K136Q, D167E, V201I, T206S, D207E, L234I, S255N, D256E, C280Y, S283GG
Parczewski (2012)235_1235_1KC409150None   K14KR, L28LI, P30S, L101I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218TS, Y227F, L234I, S255N, D256E, S283GG
 914_1914_1KC409212None   G4N, K14KR, L28I, P30A, Y99F, L101I, K103KR, T112TA, T124G, T125A, G134N, K136T, D167E, H171Y, V201I, K211R, D232E, L234I, D256E, S283GG
Zhao (2012)LT31LT31JN864056None   K14R, V31I, L101I, T112V, T124A, T125A, I135V, K136Q, V201I, T206S, I208L, D232N, L234I, K236X, S255N, D256E, R269K, S283GG
Reigadas (2013)310310JX425431None   S17N, V32I, L45LQ, M50MI, I72V, L101I, T112A, T125A, G134D, K136T, Q137H, F185FY, V201I, I203M, L234I, D256E, D270N, S283G, D288NG
 322322JX425443None   E11D, K14R, V32I, L101I, T112I, T122I, T125A, G134N, K136T, V201I, T206S, K211R, E212I, Y227F, L234I, S255N, D256E, S283GG
 323323JX425446None  L74LIME11D, K14R, V32I, L101I, T112I, T124TA, T125A, G134N, K136T, V201I, T206S, K211KR, E212AT, Y227F, L234I, S255N, D256E, S283GG
 343343JX425464None   E11D, S24N, I84IM, L101I, T112V, T124A, G134N, K136T, V201I, I208L, L234I, D256E, S283GG
 345345JX425466None   D6E, K14E, R20K, I84M, L101I, T112V, T124A, T125A, G134N, K136T, H171Y, V201I, I208L, L234I, A265T, S283GG
 490490JX425823None   K14R, S24N, L74I, T112I, T124N, T125A, G134N, K136T, V201I, T206S, L213Q, D232N, L234I, S255N, D256E, S283G, R284G, D286NG
 750750JX425876None   E11D, K14R, A21T, V32I, S39C, L101I, T112TIM, T124A, T125A, G134N, K136T, E157EQ, D167DE, V201I, I203M, T206S, Y227F, L234I, S255N, D256E, S283GG
 751751JX425877None  L68VE11D, E35EK, K71KR, L74LV, L101I, T112R, S119P, T124A, T125A, G134D, K136T, K188R, V201I, T206S, L234I, S255N, D256E, D279DG, S283GG
 754754JX425880None   S17N, R20K, L101I, T112V, T124N, G134N, K136T, K173R, V201I, T206S, L234I, S255N, D256E, S283GG
 757757JX425883None   E11D, E13D, S24N, V31I, L45V, M50I, G59E, I84M, L101I, T112A, T124A, G134N, K136T, G163A, V201I, T206S, I208M, Y227F, L234I, S255N, D256E, S283GG
 758758JX425884None   G4GS, K14R, S17C, K34KR, M50I, I72IV, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I220IL, L234I, S255N, M275MV, D278DG, S283GG
 100989100989JX451921None   S17N, L28I, P30A, I72IV, L101I, T112A, T124A, T125A, G134N, K136T, D167E, V201I, L234I, D256E, S283GG
 101010101010JX451923None  L68VE11D, R20K, V31I, L101I, K111N, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 100927100927JX451924None   L2*, D3S, S17N, L28I, P30A, I72IV, L101I, T112A, T124A, T125A, G134N, K136T, D167E, V201I, L234I, D256E, S283GG
 4126141261JX451934None   K14R, V31I, S39SN, K42R, I84M, T112V, T124N, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, R269K, S283GG
 4218842188JX451944None   K14R, L28I, V31I, V32I, I72V, L101I, T112V, S123C, T124A, T125A, G134N, K136T, D167E, V201I, L234I, D256E, S283GG
 100980100980JX451949None   G4S, L28I, P30A, M50ML, I72IV, L101I, T112A, T124AG, T125A, K127KR, G134N, K136T, D167E, H171Y, V201I, L234I, D256E, S283SGG
 4143441434JX451960None  V151IK14R, V31I, D41N, L101I, T112V, T124A, T125A, G134D, I135V, K136T, D167E, V201I, I203IM, L234V, D256E, S283GG
 100812100812JX451962None   D3E, G4S, L28I, P30A, I72V, L101I, T112A, T124A, T125A, G134N, K136T, D167E, H171Y, V201I, L234I, D256E, S283GG
 4159341593JX451963None  V151ID3E, G4S, K7KR, K14R, V31I, V32I, I72V, L101I, T112V, T124A, T125A, G134N, K136T, D167E, V201I, L234I, D256E, S283GG
Han (2015)SH2007052SH2007052KP178442None   K14R, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S255N, D256E, I268L, R269K, D278G, V281M, S283GG
Hora (2015)DEMG09ES002DEMG09ES002JX140675None   K14R, S17N, L101I, T112I, T124A, G134N, K136T, G163M, K173R, V201I, T206S, I208L, L234I, S255N, D256E, S283GG
 DEMG09KE001DEMG09KE001KF716477None  L74M, T97AK14R, V31I, I72V, L101I, T112V, T122I, T124A, T125A, G134N, K136T, K173R, I200M, V201I, T206S, L234I, S255N, S283GG
 DE01405ES002DE01405ES002KC473837None   K14R, G106A, T112I, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283G, D288EG
 DEMG05ES001DEMG05ES001JX140674None   S24N, V31I, Y99F, L101I, T112M, S119G, T124N, T125A, G134N, K136T, K173R, V201I, T206S, T218I, L234I, D256E, S283GG
 DE02408ES002DE02408ES002KC473838None   E11Q, M50I, I72V, L101I, T112V, S119P, T122I, T124A, T125A, G134D, K136T, V201I, T206S, T210I, Y227F, L234I, S255N, D256E, D270H, S283GG
 DEURF10CM020DEURF10CM020KP109502None   K14R, V32I, L45I, L74I, I84M, Q95P, L101I, T124N, G134N, K136T, V201I, T206S, L234I, D256E, S283GG
 DE01405BR001DE01405BR001JX140649None   K14R, S17N, L28I, L101I, S119T, T124A, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Tongo (2015)BS48BS48KR017776None   K14R, V31I, T112I, T124N, G134N, K136T, V201I, T206S, I208M, L234I, I251V, S255N, D256E, S283GG
 BS40BS40KR017774None   E11D, V31I, L74I, L101I, T112V, T124A, T125A, G134D, K136Q, V201I, T206S, Y227F, L234I, S255N, D270N, S283GG
Wilkinson (2015)TV546TV546KJ948662None   K14R, V31I, L74I, T112V, T124Q, T125A, G134S, K136T, V201I, L234I, S255N, D256E, I267V, I268L, S283GG
Billings (2016)KE275457V6KE275457V6KT022379None   K14R, V31I, A33T, E69K, L101I, G106A, T112V, T125V, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
Heipertz (2016)NG020134NG020134KX389619None   E11D, E13D, R20K, M50I, K71R, L101I, K111T, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S255N, D256E, R269K, D278G, S283GG
 NG010145NG010145KX389632None   K14R, D25E, V31I, S39C, M50I, L63I, L74I, T112V, T124A, T125A, G134S, K136Q, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 NG010105NG010105KX389635None   K7R, K14R, V31I, L101I, T112V, S119PT, T124N, G134N, K136T, L172LF, V201I, T206S, I208L, E212I, T218TS, D229E, S255N, D256E, M275V, S283GG
 NG010079NG010079KX389636None   E10G, V31I, S39N, L74I, T112V, T124N, T125A, G134N, K136Q, D167E, V201I, T206S, I208L, T218S, Y227F, L234I, S255N, D256E, S283GG
 NG050489NG050489KX389645None   K14R, K42R, S57G, T112M, T124G, T125A, G134D, Q137H, V201I, T206S, D207E, L234I, S255N, D256E, S283GG
 NG060248NG060248KX389646None   V31I, L101I, T112V, T124N, T125A, G134N, K136T, V201I, T206S, K219Q, L234I, S255N, D256E, S283GG
 NG010205NG010205KX389628None   K14R, S17N, L101I, K103KR, K111Q, T112V, T124N, G134N, K136T, V201I, T206S, K211R, E212AT, L234I, Q252K, S255N, D256E, S283GG
 NG010261NG010261KX389626None   K14R, S17N, M50I, L101I, T112I, T124N, T125V, G134N, K136T, V201I, T206S, I208L, Y227F, L234I, D256E, S283GG
 NG060409NG060409KX389648None   K14R, R20K, M50I, L101I, T112V, T124N, T125A, G134S, K136T, V201I, T206S, I208M, I217V, T218S, L234I, S255N, D256E, I268L, S283GG
 NG010483NG010483KX389623None   R20K, V31I, M50I, I72V, T112I, T124N, K136T, V165I, G193E, V201I, T206S, I217V, T218S, Y227F, L234V, S255N, D256E, D279G, S283GG
 NG010157NG010157KX389631None   S17N, V31I, I84M, Y99H, L101I, T112I, T124N, T125A, G134N, K136T, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 NG010315NG010315KX389625None   E10ED, E11ED, K14R, L74I, Q95S, T112V, T124S, T125A, G134N, K136T, V201I, T206S, I208L, L234I, S255N, D256E, S283GG
 NG050158NG050158KX389641None  E138DE11D, K14R, S24N, V31I, A91T, L101I, T112V, T124N, T125A, G134N, K136T, G163A, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG
 NG020303NG020303KX389618None   K14R, S17N, V31I, M50I, Q53K, I72V, L101I, T112V, T124N, G134N, K136T, V165I, V201I, T206S, D229E, S255N, D256E, S283G, R284GG
 NG050272NG050272KX389642None   K14R, R20K, L101I, K111R, T124N, G134N, K136T, V201I, T206S, L234I, S255N, D256E, R269K, S283G, D286DGG
 NG020420NG020420KX389615None   K14R, R20K, V31I, M50T, L101I, T112V, T124N, G134N, K136T, A196AV, V201I, T206S, L234I, S255SN, D256E, S283GG
 NG020133NG020133KX389620None   S17N, N27G, V31I, I72V, L101I, T112V, S119P, T124N, G134N, K136T, D167E, V201I, T206S, I208L, K211R, L234I, S255N, D256E, S283GG
 NG010073NG010073KX389637None   K14R, V31I, S39C, M50I, L63I, L74I, T112V, T124A, T125A, G134S, K136Q, V201I, T206S, Y227F, L234I, S255N, D256E, S283GG