<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype F
Gene IN
Mutation L74I
Rx II-naive
IncludeMixtures No
References 8
Patients 10
Isolates 10
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Thomson (2004)99UFRJ_999UFRJ_9AY455783None   S17N, L74I, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234V, D256E, S283GF
de Sa Filho (2005)BREPM108BREPM108AY771589None  L68IE11D, S17N, I72V, L74I, I84L, L101I, K111R, S119T, T125A, M154I, V165I, Q177L, F181Y, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 BREPM119BREPM119AY771590None  L68VE11D, S17N, A21S, V31I, E48K, I72V, L74I, I84L, A98G, L101I, K111R, S119P, T122I, T125A, G163E, V165I, V201I, A205S, K211R, S230N, L234I, D256EF
Brennan (2007)01BAB09601BAB096EF150622None   S17N, L74I, L101I, K111R, S119P, T125A, V126A, M154I, G163E, V165I, V201I, A205S, T206S, K211R, T218I, L234V, D256E, I268L, D279G, S283GF
 01GOB03901GOB039EF150627None   S17N, S24N, M50T, S57G, I72V, L74I, I84L, L101I, K111R, S119P, M154I, V165I, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
Garrido (2009)408INT-408GU217255None  L68VE11D, S17N, V32I, I72V, L74I, I84L, E96D, L101I, S119T, K136Q, V165I, V201I, K211R, T218I, Q221R, R231RK, L234V, V250VA, D256E, S283GF
Sichtig (2009)39753975FJ183592None   K14R, V31I, M50I, L63I, L74I, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, T218S, Y227F, L234I, S255N, D256EF
Reigadas (2013)307307JX425428None   S17N, D41N, K71R, L74I, I89M, A91S, L101I, T124S, T125A, A129X, K136Q, H171Q, K173R, G193E, V201I, T218I, L234V, D256E, S283G, D286NF
Pessoa (2016)10BR_RJ09410BR_RJ094KT427758None   E11D, S17N, V31I, S39N, L68E, L74I, L101I, S119T, T124N, T125A, I135V, V165I, V201I, A205S, K211R, T218I, D232E, L234V, D256E, S283GF
Rodgers (2017)CG-0349-02CG-0349-02KY392770None   V37I, I72V, L74I, T112L, T124A, T125A, K136Q, V201I, A205S, T206S, L234V, D256E, S283GF