<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype F
Gene IN
Mutation T206S
Rx II-naive
IncludeMixtures No
References 16
Patients 29
Isolates 31
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Carr (1999)JKC-VI1126VI1126AF076475None   S17N, V31I, Y99F, L101I, T112I, T122I, T124A, K136Q, P142S, V165I, T206S, K211R, E212A, L234I, D256E, S283GF
Carr (2001)ARMA037ARMA037AY037277None  G163KS17N, L28I, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, L234V, D256E, S283GF
Hierholzer (2002)BZ126BZ126AY173957None  G163RS17N, I72V, I84L, A91T, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
 BZ163BZ163AY173958None  G163KS17N, C56X, I72V, I84L, A91T, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
Thomson (2002)A047A047AF408627None  G163RS17N, I72V, I84L, I113V, S119P, T124A, T125A, K136Q, V201I, A205S, T206S, D207E, L234V, D256E, S283GF
Swanson (2003)BZ126BZ126AY214074None  G163RS17N, I72V, I84L, A91T, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
 BZ163BZ163AY214076None  G163KS17N, I72V, I84L, A91T, L101I, G106E, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
Brennan (2007)01BAB09601BAB096EF150622None   S17N, L74I, L101I, K111R, S119P, T125A, V126A, M154I, G163E, V165I, V201I, A205S, T206S, K211R, T218I, L234V, D256E, I268L, D279G, S283GF
Brennan (2008)147-19147-19EU618090None   V31I, D55N, L101I, T112I, T125V, K136Q, G163E, V201I, T206S, Y227F, L234V, S255N, D256E, S283G, R284G, E287KF
 179-22179-22EU618107None  T97A, A128TE11D, E13D, L101I, T112I, T125V, K136Q, V201I, T206S, L234I, V281M, S283GF
 4463-134463-13EU618189None   V31I, G70E, L101I, T112I, S119R, T125V, K136Q, G163T, V201I, T206S, Y227F, L234I, S255N, D256E, S283G, R284G, E287QF
 884-33884-33EU618320None   K7R, D55N, L101I, T112I, T125V, K136Q, G163E, V201I, T206S, Y227F, L234V, S255N, D256E, S283G, R284G, E287TF
 A1227A1227EU618369None   V31VI, L101I, T112I, T125V, K136Q, V201I, T206S, T218I, D229E, L234I, S255D, D256E, S283GF
 A1785A1785EU618450None   R20K, M50I, L101I, T112I, T125V, I135V, K136Q, G163S, V201I, T206S, I208IL, Y227F, L234I, S255N, D256E, S283G, E287QF
Garrido (2009)43INT-43GU216890None   T112V, I113V, S119P, T125V, K136Q, V201I, A205S, T206S, Y227F, L234V, S255N, D256EF
 193INT-193GU217040None   E13ED, S17N, R20K, A49S, L101I, T112I, T124G, T125A, K136Q, G193D, V201I, A205S, T206S, L234V, D256EF
 194INT-194GU217041None   E13D, S17N, L28I, P30A, L101I, T112M, S119P, T124S, T125A, K136Q, V165I, V201I, A205S, T206S, T218I, L234V, S255R, D256E, I257MF
 216INT-216GU217063None   V32VI, D55N, L101I, T112V, I113V, S119P, T125V, K136Q, G163E, K173KR, V201I, T206S, Y227F, L234V, S255N, D256EF
 294INT-294GU217141None   V31I, M50I, L101I, T112V, T125V, I135V, G163S, V201I, A205S, T206S, T218S, Y227F, L234I, S255N, D256EF
Huang (2009)KitaBCF-KitaFJ183726None   K14R, R20K, L101I, T112I, S123SG, T124A, T125TA, K136Q, D167E, V201I, T206S, L234I, D256E, S283GF
Passaes (2009)BR.RJ.FT90BR.RJ.FT90HM026843None   S17N, V31I, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, L234V, D256E, S283GF
 BR.RJ.UD258BR.RJ.UD258HM026861None   S17N, V32I, I72V, A76V, I84L, L101I, S119P, T124A, T125A, G134S, K136Q, V165I, V201I, A205S, T206S, T218I, L234V, D256E, S283GF
 BR.RJ.UD508BR.RJ.UD508HM026864None   S17N, V31I, I72V, V77A, I84L, L101I, S119P, T124A, T125A, K136Q, D167E, V201I, A205S, T206S, E212I, T218I, L234V, D256E, S283GF
Arruda (2010)EI035EI035GQ864183None   S17N, V31I, L101I, S119T, T124A, I135V, K136Q, G163A, V201I, A205S, T206S, T218I, L234V, D256E, S283GF
Sanabani (2010)81207BR_FPS812HM026460None   S17N, V32I, I72V, I84L, L101I, S119P, T124A, T125A, G134N, K136Q, V201I, T206S, I208M, K211R, T218I, L234V, D256E, V259I, S283GF
Brenner (2011)82598259HQ207773None   E13D, K14R, V31I, M50I, L101I, T112IV, S119IT, T124G, T125A, G134S, V201I, T206S, I220L, Q221S, L234I, A265V, S283GF
Armenia (2012)PT_80PT_80_BLJN544102None   S17N, L101I, T112R, S119T, T124A, T125A, K136Q, K156N, G193E, V201I, A205AS, T206S, T210TI, E212Q, L234V, D256E, D279GF
Monleau (2012)DRC-810DRC-810JQ250590None   Q9QL, E11D, A23AV, V37I, I72V, K111R, T112L, T124N, T125A, K136Q, V201I, T206S, L234V, D256E, S283GF
Reigadas (2013)308308JX425429None   K14R, S17N, V32I, L45Q, M50I, A98G, L101I, T124A, T125A, A133X, K136Q, V201I, T206S, Y227F, L234V, S255N, D256E, D270H, S283GF
 340340JX425461None   S17N, D25E, P30A, V32I, L45V, G59E, L101I, T112R, T124S, T125A, K136Q, V201I, T206S, T218I, L234V, D256E, R269RG, D279GS, S283GF
 753753JX425879None   E11ED, L101I, T122I, T124N, G193E, S195T, T206S, Y227F, L234I, S255N, D256E, S283GF