<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype F
Gene IN
Mutation G163S
Rx II-naive
IncludeMixtures No
References 6
Patients 11
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Thomson (2002)A027A027AF332867None   S17N, I72V, I84L, P90S, L101I, S119T, T124A, K136Q, G163S, V201I, A205S, K211R, T218I, L234V, S255N, D256E, S283GF
 A32989A32989AF408630None   S17N, D64N, I72V, I84L, T112I, S119P, T124N, K136Q, G163S, D167E, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
Brennan (2007)182189182189EF150617None   S17N, I72V, I84L, S119T, T124G, T125A, K136Q, G163S, V201I, L234V, D256E, S283GF
Brennan (2008)172-8172-8EU618102None   K14R, M50T, T112I, T125V, K136Q, G163S, V201I, Y227F, L234I, S255N, D256E, S283GF
 A1785A1785EU618450None   R20K, M50I, L101I, T112I, T125V, I135V, K136Q, G163S, V201I, T206S, I208IL, Y227F, L234I, S255N, D256E, S283G, E287QF
 AB1065AB1065EU618471None   K34R, M50I, L101I, T112I, T125V, K136Q, G163S, G193R, V201I, K211R, Y227F, L234I, S255N, D256E, S283GF
 ABB66-96ABB66-96EU618552None   E11D, M50I, L63LS, L101I, T112I, T125V, K136Q, G163S, V201I, I208L, K211R, Y227F, L234I, S255N, D256E, S283G, E287DF
Eshleman (2009) ABB66-96FJ480287None   E11D, M50I, L101I, T112I, T125V, K136Q, G163S, V201I, I208L, K211R, Y227F, L234I, S255N, D256E, A265V, S283G, E287DF
 ARG2795ARG2795FJ480321None   E11D, S17T, V37I, I72V, I84L, A98G, L101I, T112V, S119P, T125A, K136Q, G163S, D167E, V201I, K211R, T218I, L234V, D256EF
Garrido (2009)294INT-294GU217141None   V31I, M50I, L101I, T112V, T125V, I135V, G163S, V201I, A205S, T206S, T218S, Y227F, L234I, S255N, D256EF
Iamarino (2012)BF.BR.1458BF.BR.1458JN234032None  V54IS17N, S39N, I72V, I84L, S119T, T124A, K136Q, G163S, V165I, V201I, A205S, L234V, D256E, S283GF
 F.BR.1075F.BR.1075JN234068None   S17N, D55N, I60V, I84L, L101I, D116N, S119T, T124A, T125A, K136Q, G163S, V201I, A205S, K211R, T218I, L234V, D256E, S283GF