<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype F
Gene IN
Mutation T125V
Rx II-naive
IncludeMixtures No
References 9
Patients 46
Isolates 48
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Triques (2000)95cm-mp25595CMMP255AJ249236None   S17N, S39N, L101I, T112I, T125V, K136Q, I141V, V165I, V201I, Y227F, L234V, S255N, D256E, S283GF
 95cm-mp25795cmmp257AJ249237None  T97AL101I, T112I, T124A, T125V, K136Q, V201I, T218S, Y227F, L234V, S255N, D256E, V260I, S283GF
Carr (2001)CM53657CM53657AF377956None   T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, S283GF
Kijak (2004)0016BBY02CM.0016AY371158None   S17N, V31I, M50I, L101I, T112I, T125V, K136Q, V201I, T218S, Y227F, L234I, S255N, D256E, A265V, S283GF
Brennan (2008)147-19147-19EU618090None   V31I, D55N, L101I, T112I, T125V, K136Q, G163E, V201I, T206S, Y227F, L234V, S255N, D256E, S283G, R284G, E287KF
 17-1717-17EU618099None   S17SN, V31VI, K42KR, L101I, S119T, T125V, K136Q, G163E, V201I, Y227F, L234V, S255N, D256E, D278DN, S283GF
 172-8172-8EU618102None   K14R, M50T, T112I, T125V, K136Q, G163S, V201I, Y227F, L234I, S255N, D256E, S283GF
 179-22179-22EU618107None  T97A, A128TE11D, E13D, L101I, T112I, T125V, K136Q, V201I, T206S, L234I, V281M, S283GF
 282-6282-6EU618139None  T97AV31I, L101I, T112I, S119T, T125V, K188KR, V201I, K211KR, Y227F, L234I, S255N, D256E, A265V, R269RK, S283GF
 311-7311-7EU618144None   E11D, T112I, T125V, K136Q, V201I, I208M, Y227F, L234I, S255N, D256E, V260I, A265V, S283GF
 39-1639-16EU618168None  G140GEK7R, M50MI, T112IV, T125V, K136Q, G163GE, V201I, I208ILM, Y227F, L234S, S255N, D256E, S283GF
 438-52438-52EU618183None   M50I, L74V, L101I, T112I, T125V, K136Q, G163E, V201I, Y227F, L234V, S255N, D256E, D279A, S283GF
 4463-134463-13EU618189None   V31I, G70E, L101I, T112I, S119R, T125V, K136Q, G163T, V201I, T206S, Y227F, L234I, S255N, D256E, S283G, R284G, E287QF
 503-02503-02EU618219None   E11D, L101I, T112I, T125V, K136Q, D167E, V201I, T218S, L234I, D256E, V281M, S283GF
 537-32537-32EU618235None   R20RK, L101I, T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, R269K, S283GF
 564-9564-9EU618247None   S17N, L101I, T125V, K136Q, G163E, V201I, I208L, Y227F, L234I, S255N, D256E, S283GF
 693-12693-12EU618282None  T97AV31I, V32I, L101I, T112I, S119T, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, V259I, A265V, S283GF
 741-31741-31EU618291None   K7R, V31I, L101I, T112I, T125V, K136Q, G163AT, K188R, V201I, T218S, Y227F, L234I, S255N, D256E, A265AV, I268L, S283GF
 747-57747-57EU618293None   R20K, L101I, T125V, I135IV, K136Q, V201I, Y227F, L234I, S255N, D256E, V259I, R269K, S283GF
 811-26811-26EU618302None   D6E, P30S, L101I, S119G, T125V, K136Q, D167E, V201I, K211R, Y227F, L234I, S255N, D256E, S283GF
 884-33884-33EU618320None   K7R, D55N, L101I, T112I, T125V, K136Q, G163E, V201I, T206S, Y227F, L234V, S255N, D256E, S283G, R284G, E287TF
 94-2694-26EU618332None   E11D, R20K, L101I, G106A, T112I, T125V, K136Q, V201I, T218S, Y227F, L234I, S255N, D256E, D278DG, S283GF
 A1227A1227EU618369None   V31VI, L101I, T112I, T125V, K136Q, V201I, T206S, T218I, D229E, L234I, S255D, D256E, S283GF
 A1699A1699EU618415None  T97AS17N, K46KQ, L101I, T112I, T125V, K136Q, G163A, V201I, T218S, Y227F, L234S, S255N, D256E, S283GF
 A1758A1758EU618430None   V31I, M50I, L101I, T112I, T125V, K136Q, V201I, Y227F, L234I, D256E, V260I, V281M, S283GF
 A1785A1785EU618450None   R20K, M50I, L101I, T112I, T125V, I135V, K136Q, G163S, V201I, T206S, I208IL, Y227F, L234I, S255N, D256E, S283G, E287QF
 A1787A1787EU618452None   L101I, T125V, I135V, K136Q, G163E, K188KR, V201I, Y227YF, L234I, S255N, D256E, A265V, S283GF
 A1797A1797EU618460None   L101I, K103R, T112I, T125V, K136Q, K188KR, V201I, I208L, Y227F, L234I, I251L, S255N, D256E, A265V, S283GF
 AB1064AB1064EU618470None  T97AV31I, L101I, T112I, T124N, T125V, K136Q, I162V, V201I, Y227F, L234I, S255N, D256E, A265V, S283GF
 AB1065AB1065EU618471None   K34R, M50I, L101I, T112I, T125V, K136Q, G163S, G193R, V201I, K211R, Y227F, L234I, S255N, D256E, S283GF
 AB1091AB1091EU618476None   E11D, T112I, T125V, K136Q, V201I, I208M, Y227F, L234I, S255N, D256E, V260I, A265V, S283GF
 ABB26-96ABB26-96EU618513None   K14R, V31VI, L101I, T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256EF
 ABB33-96ABB33-96EU618520None  T97AL101I, T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, S283GF
 ABB51-96ABB51-96EU618538None   E10D, L101I, T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, S283GF
 ABB66-96ABB66-96EU618552None   E11D, M50I, L63LS, L101I, T112I, T125V, K136Q, G163S, V201I, I208L, K211R, Y227F, L234I, S255N, D256E, S283G, E287DF
 ABB189ABB189EU618616None   T112I, T125V, K136Q, V165I, V201I, Y227F, L234V, N254D, S255N, D256E, S283GF
Eshleman (2009)ABB026-96ABB026-96FJ480273None   E11ED, K14R, S24SN, V31VI, L101I, T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, S283SG, D286DNF
 ABB033-96ABB033-96FJ480278None  T97AL101I, T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, S283GF
 ABB51-96ABB51-96FJ480281None   E10ED, L101I, T112I, T125V, K136Q, V201I, Y227F, L234I, S255N, D256E, S283GF
 ABB66-96ABB66-96FJ480287None   E11D, M50I, L101I, T112I, T125V, K136Q, G163S, V201I, I208L, K211R, Y227F, L234I, S255N, D256E, A265V, S283G, E287DF
Garrido (2009)43INT-43GU216890None   T112V, I113V, S119P, T125V, K136Q, V201I, A205S, T206S, Y227F, L234V, S255N, D256EF
 216INT-216GU217063None   V32VI, D55N, L101I, T112V, I113V, S119P, T125V, K136Q, G163E, K173KR, V201I, T206S, Y227F, L234V, S255N, D256EF
 294INT-294GU217141None   V31I, M50I, L101I, T112V, T125V, I135V, G163S, V201I, A205S, T206S, T218S, Y227F, L234I, S255N, D256EF
Sichtig (2009)30443044FJ183593None   S17N, R20K, L28I, L45V, I72V, I84L, L101I, T112I, S119P, T122I, T124A, T125V, K136Q, K156R, D167E, V201I, A205S, K211R, T218L, L234V, D256EF
 31103110FJ183594None   I72V, I84L, L101I, T112I, S119P, T122I, T124A, T125V, K136Q, K156R, D167E, N184NI, V201I, A205S, K211R, T218L, Y227YH, L234V, D256EF
 13201320FJ183610None   I72V, L101I, T112IV, T124N, T125V, K136Q, G163T, V165VI, V201I, Y227F, L234V, S255D, D256EF
Monleau (2012)SK1017SK1017JQ250537None   E11D, S24G, D25E, S39C, L45V, M50V, L101I, T112I, T125V, K136Q, V165VI, V201I, Y227F, L234V, D256EF
Reigadas (2013)313313JX425434None  E138DS17N, G70GE, E87EK, T93TS, L101I, R107RK, T112I, T125V, K136Q, G163A, K173KR, V201I, T206TS, E212EA, Y227F, L234V, D256E, S283GF