<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype F
Gene IN
Mutation T125A
Rx II-naive
IncludeMixtures No
References 45
Patients 166
Isolates 170
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Laukkanen (2000)FIN9363FIN9363AF075703None   S17N, E96D, L101I, T112M, T124A, T125A, K136Q, V201I, I217V, L234V, D256E, S283GF
Triques (2000)LVMP411LVMP411AJ249238None   S17N, L101I, T112I, T124S, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
Carr (2001)ARCH003ARCH003AY037267None  V151IE11D, S17N, I72V, I84L, L101I, T125A, K136Q, V165I, V201I, A205S, K211R, K215N, T218I, L234V, D256E, S283GF
 BOL137BOL137AY037271None  V54I, G163RE11D, V37I, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 URTR17URTR17AY037272None  S153YS17N, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, K215N, T218I, L234V, D256E, S283GF
 ARMA037ARMA037AY037277None  G163KS17N, L28I, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, L234V, D256E, S283GF
 ARMA097ARMA097AY037280None  G163RE11D, S24N, I72V, I84L, L101I, S119T, T125A, K136Q, V201I, I204V, A205S, K211R, T218I, L234V, D256E, S283GF
 ARMA038ARMA038AY037281None  V54I, G163RS17N, I84L, L101I, S119P, T122S, T124N, T125A, K136Q, V165I, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 URTR23URTR23AF385934None  G163KS17N, L45V, I84L, S119T, T122S, T124A, T125A, K136Q, V201I, A205S, T218I, L234V, D256E, S283GF
 URTR35URTR35AF385935None   E11D, S17N, I72V, I84L, L101I, K111R, S119P, T122S, T124A, T125A, I135V, K136Q, G163H, V201I, T218I, S230N, L234V, D256E, S283GF
Hierholzer (2002)BZ126BZ126AY173957None  G163RS17N, I72V, I84L, A91T, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
 BZ163BZ163AY173958None  G163KS17N, C56X, I72V, I84L, A91T, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
Mokili (2002)90CD121E1290CD121E12AF457101None   V31I, M50I, E96D, L101V, K111T, T124A, T125A, K136Q, D167E, V201I, T218I, K219Q, L234I, D256E, D288NF
Thomson (2002)A047A047AF408627None  G163RS17N, I72V, I84L, I113V, S119P, T124A, T125A, K136Q, V201I, A205S, T206S, D207E, L234V, D256E, S283GF
 A32879A32879AF408629None   E11D, S17N, I72V, I84L, L101I, K111R, S119P, T122I, S123N, T125A, K136Q, D167E, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 A050A050AF408631None   S17N, I72V, I84L, L101I, S119P, T122I, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
Swanson (2003)BZ126BZ126AY214074None  G163RS17N, I72V, I84L, A91T, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
 BZ163BZ163AY214076None  G163KS17N, I72V, I84L, A91T, L101I, G106E, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, Q221R, L234V, D256E, S283GF
Sierra (2004)CH12CH12AY536235None R263RKT66TP, G163RE11D, V31I, V32I, V37I, M50I, I72V, I84L, P90S, F100FL, L101I, N117NK, S119P, T124A, T125A, W132WG, G134D, K136Q, V201I, K211R, T218I, I220IF, R224RW, L234V, K240R, N254NI, D256EF
 R140R140AY536237None   E10D, I72V, I84L, L101I, S119P, T124A, T125A, K136Q, H171Y, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 X1241X1241AY536238None  G163KS17N, I72V, I84L, L101I, S119T, T122S, T124A, T125A, K136Q, D167E, V201I, T218I, L234V, D253E, D256EF
Thomson (2004)99UFRJ_999UFRJ_9AY455783None   S17N, L74I, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234V, D256E, S283GF
 99UFRJ_1699UFRJ_16AY455782None  G163KS17N, I72V, L101I, S119T, T122I, T124A, T125A, K136Q, V201I, A205S, L234V, D256E, S283GF
Aulicino (2005)ARE933ARE933DQ189088None   E11D, S17N, I72V, I84L, L101I, V110A, S119P, T124A, T125A, A129S, K136Q, A205S, K211R, T218I, L234V, D256E, V281M, S283GF
de Sa Filho (2005)BREPM108BREPM108AY771589None  L68IE11D, S17N, I72V, L74I, I84L, L101I, K111R, S119T, T125A, M154I, V165I, Q177L, F181Y, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 BREPM119BREPM119AY771590None  L68VE11D, S17N, A21S, V31I, E48K, I72V, L74I, I84L, A98G, L101I, K111R, S119P, T122I, T125A, G163E, V165I, V201I, A205S, K211R, S230N, L234I, D256EF
Vinoles (2005)01UYTRA102001U_1020AY781128None   D6E, E11D, S17N, L45I, I84L, L101I, S119P, T124A, T125A, K136Q, V201I, A205S, T218I, L234V, D256EF
Pando (2006)04AR16067704AR160677DQ383754None   E11D, E13D, V37I, I60V, I84M, L101I, T112V, T124N, T125A, I135V, K136Q, V165I, V201I, A205S, I217V, T218S, L234V, D256E, S283GF
Sanabani (2006)01BR04201BR042DQ358799None   S17N, V31I, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, T218I, L234V, D256E, S283GF
 01BR04701BR047DQ358800None  G163RS17N, V32I, I72V, I84L, K103R, K111R, T112A, S119P, T124A, T125A, K136Q, V201I, L234V, D256E, S283GF
 01BR08701BR087DQ358801None   S17N, I72V, I84L, L101I, S119P, T124A, T125A, K136Q, H171Y, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 01BR12501BR125DQ358802None  G163KS17N, I72V, I84L, E96D, L101I, T112I, S119P, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
Brennan (2007)182189182189EF150617None   S17N, I72V, I84L, S119T, T124G, T125A, K136Q, G163S, V201I, L234V, D256E, S283GF
 01BAB06001BAB060EF150620None   E10D, V32I, I72V, L101I, T112I, S119T, T124A, T125A, K136Q, G163T, N222K, L234V, N254S, V259I, I268L, S283GF
 01BAB09601BAB096EF150622None   S17N, L74I, L101I, K111R, S119P, T125A, V126A, M154I, G163E, V165I, V201I, A205S, T206S, K211R, T218I, L234V, D256E, I268L, D279G, S283GF
 01CEB09001CEB090EF150629None  G163RS17N, V32I, L45I, I84L, L101I, K111R, S119T, T122S, T124A, T125A, K136Q, V165I, V201I, K211R, T218I, L234V, D256E, S283GF
 01CEB09201CEB092EF150630None  L74LIM, T97AS17N, L28I, P30A, I72V, V77VA, I84L, L101I, S119T, T124A, T125A, K136Q, V165I, V201I, L234V, D256E, S283GF
 3781137811EF150631None  E138DS17C, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
van der Hoek (2007)95.H10986_B695.H_B6EF029067None   E11D, S17T, F100Y, L101I, T112V, S119P, T124A, T125A, V201I, I203M, K211T, L234I, D256EF
 95.H10986_D195.H_D1EF029066None   E11D, S17T, I60M, V77A, F100Y, L101I, T112V, S119P, T124A, T125A, V201I, I203M, K211T, L234I, D256E, M275VF
 01.H10986_D101.H_D1EF029068None   E11D, S17T, V37I, V77A, F100Y, L101I, T112V, S119P, T124A, T125A, I191V, V201I, K211T, L234I, D256E, S283NF
 01.H10986_C1101.H_C11EF029069None   E11D, S17T, V37I, K42R, V77A, F100Y, L101I, T112V, S119P, T124A, T125A, V201I, K211T, L234I, D256EF
Brennan (2008)0031-10031-1EU618056None   K14R, V31I, I72V, A98G, L101I, T112I, T125A, K136Q, G163T, V201I, Y227F, L234I, S255N, D256E, A265V, D288NF
 440-1440-1EU618185None   D6E, E11D, S17T, A23V, V37I, S39SN, L101LI, T124N, T125A, K136Q, V201I, Y227F, L234V, S255N, D256E, S283GF
 ABB95-97ABB95-97EU618580None   S17N, R20K, K71R, I84L, L101I, S119T, T124A, T125A, K136Q, D167E, V201I, T218I, L234V, D256E, S283GF
Van Laethem (2008)AR04-538AR04-538EU882771None   S17N, L101I, T112R, T124A, T125A, G134D, K136H, G193D, V201I, Q216QR, L234I, D256E, A265AT, I268IL, D270DH, S283G, D286NF
Brumme (2009)H2522H2522GQ371911None   E11D, V37I, I72V, I84L, L101I, S119P, T122V, T124A, T125A, K136Q, G163QF
Eshleman (2009)182.189182.189FJ480231None   S17N, I72V, I84L, S119T, T124GS, T125A, K136Q, G163NS, V201I, L234V, D256E, S283GF
 3781137811FJ480243None  E138DS17C, I72V, I84L, L101I, S119T, T124A, T125A, I135IV, K136Q, G163GS, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 ABB95-97ABB95-97FJ480295None   S17N, R20K, K71R, I84L, L101I, S119T, T124A, T125A, K136Q, D167E, V201I, T218I, L234V, D256E, S283GF
 ARG2795ARG2795FJ480321None   E11D, S17T, V37I, I72V, I84L, A98G, L101I, T112V, S119P, T125A, K136Q, G163S, D167E, V201I, K211R, T218I, L234V, D256EF
 BrRJ96-042BrRJ96-042FJ480333None   E11D, S17N, V32I, K42R, I72V, Y99YF, L101LI, S119P, T122TI, T124A, T125A, K136Q, V165I, V201I, K211R, T218I, L234V, D256E, S283GF
Garrido (2009)120INT-120GU216967None   A49AP, I72V, I84L, L101I, S119T, T122S, T124A, T125A, K136Q, Q177R, V201I, A205S, K211R, T218I, L234V, D256EF
 193INT-193GU217040None   E13ED, S17N, R20K, A49S, L101I, T112I, T124G, T125A, K136Q, G193D, V201I, A205S, T206S, L234V, D256EF
 194INT-194GU217041None   E13D, S17N, L28I, P30A, L101I, T112M, S119P, T124S, T125A, K136Q, V165I, V201I, A205S, T206S, T218I, L234V, S255R, D256E, I257MF
 197INT-197GU217044None  G163KG47R, I72V, I84L, L101I, S119P, T125A, K136Q, K160Q, V201I, A205S, K211R, T218I, Q221T, L234V, D256EF
 239INT-239GU217086None   E11D, E13D, R20K, S39N, L101I, T112R, T124G, T125A, I135IV, K136Q, G193E, V201I, T218I, L234V, D253DE, D256EF
 413INT-413GU217260None   A91T, E96D, L101I, S119R, T124N, T125A, K136Q, V201I, T218I, L234V, L242S, W243G, D256E, S283GF
Passaes (2009)BR.RJ.FT12BR.RJ.FT12HM026838None   S17N, V32I, K42R, I72V, L101I, S119P, T124A, T125A, K136Q, V165I, V201I, K211R, T218I, L234V, D256EF
 BR.RJ.FT42BR.RJ.FT42HM026840None   S17N, S24N, L45I, I72V, F100Y, L101I, S119P, T124A, T125A, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 BR.RJ.FT86BR.RJ.FT86HM026842None   S17N, L101I, S119T, T124A, T125A, K136Q, I191M, V201I, K211R, T218I, L234V, D256E, S283G, D286NF
 BR.RJ.FT90BR.RJ.FT90HM026843None   S17N, V31I, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, T206S, T218I, L234V, D256E, S283GF
 BR.RJ.FT99BR.RJ.FT99HM026844None  G163KS17N, R20K, I72V, I84L, P90S, L101I, K111R, S119T, T124A, T125A, K136Q, V201I, A205S, I208L, K211R, T218I, L234V, D256E, S283GF
 BR.RJ.SB67BR.RJ.SB67HM026846None   E11D, S17N, I72V, I84L, L101I, S119T, T124A, T125A, K136H, V165I, V180I, V201I, A205S, K211R, T218I, L234V, A265VF
 BR.RJ.SB106BR.RJ.SB106HM026847None  G163RH16P, I72V, I84L, P90S, L101I, S119T, T124A, T125A, K136Q, K156N, V201I, A205S, T218I, S230SC, L234V, D256E, V281R, S283SGF
 BR.RJ.SB114BR.RJ.SB114HM026848None   E11D, S17N, I84L, L101I, S119T, T124A, T125A, K136Q, V165I, V201I, A205S, T218I, L234V, D256E, S283GF
 BR.RJ.SB120BR.RJ.SB120HM026849None   E11D, K14R, N18Y, V32I, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 BR.RJ.SB135BR.RJ.SB135HM026850None   K14R, S17N, L101I, T112I, S119P, T124A, T125A, I135V, K136Q, V165I, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 BR.RJ.SB167BR.RJ.SB167HM026853None  L68VE11D, S17N, I72T, V79VA, I84L, E96D, L101I, S119P, T124A, T125A, K136Q, V165I, V201I, K211R, T218I, L234V, D256E, S283GF
 BR.RJ.TR13BR.RJ.TR13HM026854None   S17N, I72V, I84L, L101I, T112I, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234I, A265V, D278N, S283GF
 BR.RJ.TRBR.RJ.TRHM026856None   S17N, V31I, I72V, V77A, I84L, L101I, S119T, T124A, T125A, I135V, K136Q, V201I, T218I, L234V, D256E, S283GF
 BR.RJ.TR97BR.RJ.TR97HM026857None   S17N, I72V, I84L, L101I, T112A, S119P, T124A, T125A, K136Q, H171Y, V201I, A205S, T218I, L234V, D256E, S283GF
 BR.RJ.TR1BR.RJ.TR1HM026858None  G163RS17N, I72V, I84L, T112I, S119T, T122S, T124A, T125A, K136Q, V201I, K211R, L234V, G247R, D256E, R269K, S283GF
 BR.RJ.UD0BR.RJ.UD0HM026859None   E11D, V37I, L45Q, I72V, I84L, L101I, K111R, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 BR.RJ.UD097BR.RJ.UD097HM026860None   S17N, I72V, I84L, L101I, T112A, S119P, T124A, T125A, K136Q, H171Y, V201I, A205S, T218I, L234V, D256E, S283GF
 BR.RJ.UD258BR.RJ.UD258HM026861None   S17N, V32I, I72V, A76V, I84L, L101I, S119P, T124A, T125A, G134S, K136Q, V165I, V201I, A205S, T206S, T218I, L234V, D256E, S283GF
 BR.RJ.UD508BR.RJ.UD508HM026864None   S17N, V31I, I72V, V77A, I84L, L101I, S119P, T124A, T125A, K136Q, D167E, V201I, A205S, T206S, E212I, T218I, L234V, D256E, S283GF
Sanabani (2009)56406BR564FJ771008None   S17N, D25E, L68S, I72V, I84L, L101I, T112V, S119T, T124A, T125A, A129V, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
Sichtig (2009)21492149FJ183557None  G163RP30PL, I72V, I84L, S119T, T122S, T124A, T125A, K136Q, G193E, V201I, T218I, L234V, D256EF
 2711rc2711rcFJ183589None   N18S, D25DV, V31I, A38AP, M50I, L63I, L74LI, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, T218S, Y227F, L234I, S255N, D256EF
 39753975FJ183592None   K14R, V31I, M50I, L63I, L74I, E96D, L101I, T112V, T124A, T125A, K136Q, V201I, T218S, Y227F, L234I, S255N, D256EF
 12361236FJ183605None   S17N, R20K, E96ED, L101I, G106GA, T112R, T124G, T125A, K136Q, V165VI, G193E, V201I, A205S, T206TS, T218L, L234I, D256EF
 12851285FJ183606None   K7R, K14R, S17N, I72V, L101I, T112I, T124A, T125A, K136Q, F181FL, V201I, A205S, L234V, D256EF
 14171417FJ183607None   K7R, K14R, S17N, R20RG, I72V, L101I, T112I, T124A, T125A, I135IV, K136Q, F181FL, V201I, A205S, L234V, D256EF
 30273027FJ183608None   S17N, R20K, E96D, L101I, G106A, T112R, T124G, T125A, K136Q, V165I, G193E, V201I, A205S, T206TS, T218L, L234I, D256EF
 24992499FJ183609None   V37VA, S57SILR, I72IV, A98G, L101I, T112I, T124NS, T125A, K136Q, D167DE, V201I, A205AS, T206TS, T218TI, L234V, D256EF
 18-E18-EFJ183637None  T97TAV31VIM, V32VI, K42KR, A91AE, L101I, T112TAIV, S119SR, T124TADN, T125A, K136KQ, K156RT, V165VIM, S195SC, V201VIF
Arruda (2010)EI034EI034GQ864182None   S17N, L28I, L45V, I72V, I84L, L101I, S119P, T124A, T125A, K136Q, Q177L, V201I, L234V, D256E, S283GF
 EI088EI088GQ864228None   S17N, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, E152K, R187K, V201I, I203M, T218I, L234V, D256EF
 EI091EI091GQ864231None   E11D, S17N, I72V, I84L, L101I, K111R, T112I, S119P, T122V, T125A, K136Q, V165I, I182V, V201I, K211R, T218I, S230N, L234V, D256E, S283GF
Sanabani (2010)56106BR_FPS561HM026455None   S17N, I84L, L101I, S119T, T124A, T125A, K136Q, H171Y, V201I, T218I, L234V, D256E, S283GF
 62507BR_FPS625HM026456None  G163KE10D, S39A, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 74207BR_FPS742HM026457None   S17N, V31I, I60M, I73V, I84L, L101I, K111R, S119T, T124A, T125A, K136Q, H171Y, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 78307BR_FPS783HM026458None  G163KS17N, S39N, I72V, E96D, L101I, S119T, T124A, T125A, I135V, K136N, G193D, V201I, A205S, K211R, T218I, L234V, D256E, I268L, D270H, S283GF
 81007BR_FPS810HM026459None  G163RS17N, R20K, I84L, S119A, T124A, T125A, K136Q, K156N, V201I, A205S, L234V, D256E, S283GF
 81207BR_FPS812HM026460None   S17N, V32I, I72V, I84L, L101I, S119P, T124A, T125A, G134N, K136Q, V201I, T206S, I208M, K211R, T218I, L234V, D256E, V259I, S283GF
Brenner (2011)184NB184NBHQ207721None   S17SN, R20K, E96D, L101I, T112R, T124A, T125A, I135V, K136Q, V201I, A205S, D232E, L234V, D256E, S283GF
Canducci (2011)Pt11Pt11blJN163908None   S17N, A23V, V31I, M50I, L101I, T124A, T125A, K136L, V201I, L234V, D256EF
Graf (2011)SC37SC37JF773840None   E10D, V31I, L45Q, I72V, I84L, L101I, I113V, S119P, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, A265V, R269K, D278A, V281MF
 SC44SC44JF773846None   V37I, D41N, L45I, I84L, S119P, T122I, T124A, T125A, K136N, M154I, V165I, V201I, A205S, K211R, T218I, L234V, D256E, S283G, D288NF
Kousiappa (2011)CY191CY191JF683744None   E11D, K14R, V31I, A80P, T124S, T125A, I135V, K136Q, G189R, V201I, I220L, Y227F, L234V, S255N, R284G, D288NF
 CY222CY222JF683771None  Q95K, G140EV32I, E35K, K42R, G70E, L101I, T112I, T124G, T125A, K136Q, E152K, M154I, E157K, R166K, V201I, L234I, D256E, V260I, S283GF
Sanabani (2011)BR2029BR2029JN692438None  V54IS17N, M22R, V77A, I84L, L101I, S119T, T124A, T125A, G134S, K136Q, I191M, V201L, A205S, K211R, L234V, D256E, S283GF
Armenia (2012)PT_5PT_5_BLJN544083None  G163KS17N, R20K, E96D, L101I, S119T, T124A, T125A, K156N, V201I, K211KR, T218I, L234V, D256EF
 PT_80PT_80_BLJN544102None   S17N, L101I, T112R, S119T, T124A, T125A, K136Q, K156N, G193E, V201I, A205AS, T206S, T210TI, E212Q, L234V, D256E, D279GF
Aulicino (2012)PE02PCR0155PCR0155EU581828None  V54IK14R, S17N, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, V201I, I203M, A205S, K211R, T218I, L234V, D256E, S283GF
 AR02ARG2233ARG2233EU581826None   S17N, I72V, V77A, I84L, L101I, S119P, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 AR02ARG1139ARG1139EU581825None  V54I, G163RS17N, L45V, I84L, E96D, L101I, S119T, T124A, T125A, K136Q, V201I, A205S, D207E, L234V, D256E, S283GF
 BO02BOL119BOL119EU581827None   S17N, I84L, L101I, S119T, T124A, T125A, K136Q, V165I, V201I, A205S, T218I, L234V, D256E, S283GF
Iamarino (2012)BF.BR.0634BF.BR.0634JN234023None   E11D, S17N, I84L, L101I, T112I, S119P, T124A, T125A, K136Q, V165I, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 BF.BR.0870BF.BR.0870JN234025None  G163RS17N, S24G, D25E, E35A, S39N, L45V, I72V, I84M, K111R, S119T, T125A, K136Q, V201I, A205S, K211R, L234V, D256E, S283GF
 BF.BR.0518BF.BR.0518JN234026None   S17N, L28I, P30A, I84L, L101I, T112I, S119P, T124A, T125A, K136Q, V201I, L234V, D253E, D256E, S283GF
 BF.BR.0534BF.BR.0534JN234027None  V54IE11D, S17N, M50I, I72V, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, L234V, D256E, S283GF
 BF.BR.1094BF.BR.1094JN234028None  V54I, T97A, G163RE11D, S17N, A21S, I72V, I84L, L101I, S119T, T124A, T125A, K136Q, S153A, V201I, A205S, K211R, Y227F, L234V, D256E, S283GF
 BF.BR.1413BF.BR.1413JN234030None   E11D, S17N, V31I, I84L, L101I, K111R, S119P, T124A, T125A, K136Q, I161T, G163N, V165I, K211R, T218I, L234V, D256E, S283GF
 BF.BR.0543BF.BR.0543JN234033None   E10A, E11D, S17N, V31I, I72T, L101I, K103R, S119P, T122I, T125A, K136N, K156N, V201I, L234V, D256E, S283GF
 F.BR.1047F.BR.1047JN234067None  G163RK7R, S17N, V54T, I84L, S119T, T124A, T125A, K136Q, V201I, A205S, K211R, L234V, D256E, S283GF
 F.BR.1075F.BR.1075JN234068None   S17N, D55N, I60V, I84L, L101I, D116N, S119T, T124A, T125A, K136Q, G163S, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 F.BR.1485F.BR.1485JN234069None   E11D, S17N, I72V, K103R, I113V, S119P, T124A, T125A, K136Q, V165I, V201I, A205S, T218I, L234V, D256E, S283GF
 F.BR.1514F.BR.1514JN234070None  G163RE11D, V31I, V32I, V37I, M50L, L101I, S119A, T124A, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256EF
 F.BR.1521F.BR.1521JN234072None   K14R, R20K, S24N, I72V, L101I, S119T, T124A, T125A, I135V, K136Q, V165I, V201I, A205S, T218I, L234I, D256E, S283GF
 F.BR.1522F.BR.1522JN234073None   R20K, I72V, L101I, T112I, S119T, T124A, T125A, I135V, K136Q, V165I, R199K, V201I, A205S, T218I, L234I, D256E, S283GF
Melo (2012)0264RI0264RIJF804807None  V54I, G163KS17N, I72V, I84L, L101I, K111R, S119P, T124A, T125A, K136Q, V150A, K188R, V201I, A205S, T210V, L234V, D256E, S283GF
 0063SP0063SPJF804806None  F121SE11D, S17T, I72V, I84L, L101I, I113L, S119P, T122I, T124A, T125A, K136Q, V201I, A205S, K211R, Y227F, L234V, D256E, S283GF
Monleau (2012)DRC-810DRC-810JQ250590None   Q9QL, E11D, A23AV, V37I, I72V, K111R, T112L, T124N, T125A, K136Q, V201I, T206S, L234V, D256E, S283GF
 DRC-469DRC-469JQ250591None  T97AK7R, S17N, G70GE, L101I, T112IV, T124G, T125A, K136Q, V165I, V201I, A205S, L234V, D256E, S283GF
 DES DESDESDESJQ250596None  G163KE11D, V37I, C56S, I72V, I84L, L101I, T112I, I113V, S119P, T122S, T124A, T125A, K136Q, V201I, K211R, T218I, L234V, D256E, S283G, D288IF
Bessong (2013)08BBVCT28ZA08BBVCT28ZAHM569281None   S17N, M50I, L101V, T112V, T124N, T125A, K136Q, T218I, L234I, D256E, S283G, D288NF
Reigadas (2013)307307JX425428None   S17N, D41N, K71R, L74I, I89M, A91S, L101I, T124S, T125A, A129X, K136Q, H171Q, K173R, G193E, V201I, T218I, L234V, D256E, S283G, D286NF
 308308JX425429None   K14R, S17N, V32I, L45Q, M50I, A98G, L101I, T124A, T125A, A133X, K136Q, V201I, T206S, Y227F, L234V, S255N, D256E, D270H, S283GF
 340340JX425461None   S17N, D25E, P30A, V32I, L45V, G59E, L101I, T112R, T124S, T125A, K136Q, V201I, T206S, T218I, L234V, D256E, R269RG, D279GS, S283GF
 346346JX425467None  T97AS17N, M50I, L101I, T112I, T124A, T125A, I135V, K136Q, V201I, K211KR, L234I, D256E, S283GF
 4224142241JX451877None   S17N, V32I, K42R, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, P238S, D256E, S283GF
 101058101058JX451886None   S17N, V32I, K42R, I72V, I84L, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, G190R, V201I, T218I, L234V, D256E, S283GF
 4193041930JX451911None   S17N, I72IV, L101I, T112I, T124G, T125A, K136Q, V201I, A205S, K215KN, T218TI, L234V, D256E, S283GF
 4153041530JX451914None   S17N, I72IV, L101I, T112I, T124G, T125A, K136Q, V201I, A205S, K215KN, T218TI, L234V, D256E, S283GF
 4001540015JX451940None   S17N, R20K, M50T, L101I, K111KR, T112I, T124TA, T125A, I135V, K136Q, V201I, D232E, L234V, D256E, S283GF
Delgado (2015)X3361X3361KJ883151None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 P2563P2563KJ883137None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 X3069X3069KJ883144None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 X3097X3097KJ883148None   S17N, L28I, I72V, A91T, E96D, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 X2873X2873KJ883140None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 X3079X3079KJ883146None   S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 X3070X3070KJ883145None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 X2898X2898KJ883141None   S17N, V32I, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 X3085X3085KJ883147None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 X3016X3016KJ883143None   E11D, S17N, I72V, A91T, E96D, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 VA0053VA0053KJ883138None   S17N, L101I, S119P, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 X2922X2922KJ883142None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 X2871X2871KJ883139None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, V259I, S283GF
 X3364X3364KJ883152None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 X3308X3308KJ883150None   E11D, S17N, V32I, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, L234V, D256E, S283GF
 X3125X3125KJ883149None   E11D, S17N, M22I, L45V, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
Hora (2015)DEMBF09ES003DEMBF09ES003JX140660None   S17N, V31I, I72V, I84L, S119T, T124A, T125A, M154L, V165I, T206S, T218I, L234V, D253E, D256EF
 DEMF210CM007DEMF210CM007JX140673None   Y15F, S17N, H51Q, T112I, T124A, T125A, K136Q, V201I, T206S, L234I, S255N, D256E, D286AF
 DEMF110ES001DEMF110ES001JX140671None   E11D, S17N, I72V, L101I, S119P, T122I, T124A, T125A, I135V, K136Q, V165I, V201I, T218I, Q221K, L234V, D256E, S283GF
 DEMBF09ES006DEMBF09ES006JX140661None   E11D, S17N, L28I, I84L, L101I, T112I, S119P, T124A, T125A, K136Q, V165I, D167E, V201I, I203M, L234V, D256E, S283GF
Pessoa (2015)10BR_RJ023RJ023KJ849797None   E10K, E11N, S17N, I72V, I84L, F100Y, L101I, S119P, T124S, T125A, K136Q, V165I, V201I, A205S, K211R, T218I, D232E, L234V, D256E, S283GF
Pessoa (2016)10BR_RJ09310BR_RJ093KT427759None   S17N, I84L, L101I, I113V, S119T, T124A, T125A, K136Q, G189R, V201I, A205S, K211R, T218I, L234V, D256E, S283GF
 10BR_RJ05510BR_RJ055KT427774None   E11D, S17T, I72V, I84L, L101I, T112I, S119P, T124S, T125A, K136Q, V201I, A205S, K211R, T218I, L234V, D256E, I268L, S283GF
 10BR_RJ04410BR_RJ044KT427776None   D3N, K14R, V32I, G70E, L101I, S119T, T124A, T125A, K136Q, L158I, V165I, V201I, T218I, L234I, D256E, S283GF
 10BR_SP06310BR_SP063KT427798None   S17N, I84L, L101I, K111R, S119T, T124A, T125A, K136Q, V201I, K211R, Q214E, T218I, L234V, D256E, S283GF
 10BR_SP02910BR_SP029KT427814None   S17N, I72V, L101I, S119T, T124A, T125A, I135V, K136Q, G163H, F181L, V201I, A205S, T206S, L234V, D256E, I268L, D270H, S283GF
 10BR_SP07010BR_SP070KT427663None   S17N, L28I, L45Q, D55N, L101I, L104I, S119T, T124A, T125A, K136Q, V165I, V201I, K211R, T218I, L234V, D256E, S283GF
 10BR_RJ09410BR_RJ094KT427758None   E11D, S17N, V31I, S39N, L68E, L74I, L101I, S119T, T124N, T125A, I135V, V165I, V201I, A205S, K211R, T218I, D232E, L234V, D256E, S283GF
Bradley-Stewart (2017)WoSSVC_INT64WoSSVC_INT64MF442503None   E11D, S17N, A21S, P30S, I60V, L101I, T112TI, T124S, T125A, K136Q, V201I, T218I, L234V, D256E, D286NF
 WoSSVC_INT79WoSSVC_INT79MF442518None   S17N, P30S, L45V, I60V, V77A, T97TI, L101I, T112V, T124S, T125A, K136Q, V165I, V201I, A205S, K211R, L234V, D256E, S283G, D288DGF
Hachiya (2017)E13-50911464LC161367LC161367None  T97TAK7R, K14R, S17N, S24N, V31X, M50MI, I72IV, I84L, L101I, K111R, S119T, T124A, T125A, K136Q, V165I, V201I, A205S, I208IL, K211R, Q214QH, I217IV, T218X, L234V, D256E, S283GF
 C13-2069066LC171004LC171004None  L74ME11D, S17N, E96D, L101I, T112R, T122TI, T124S, T125A, K136E, K160R, V201I, A205S, K211R, T218L, L234V, D256E, I268L, R269K, D270H, S283GF
Rodgers (2017)CG-0349-02CG-0349-02KY392770None   V37I, I72V, L74I, T112L, T124A, T125A, K136Q, V201I, A205S, T206S, L234V, D256E, S283GF

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