<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype F
Gene IN
Mutation T125A
Rx >=1 INI
IncludeMixtures No
References 5
Patients 8
Isolates 9
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Charpentier (2010)T076006T076006HQ717830RAL   S17N, R20K, I73V, L101I, T112R, T124S, T125A, I135V, K136E, V201I, A205S, T218I, L234V, D256E, S283GF
Brenner (2011)1108111081HQ423446RAL N155H E11D, S17N, M50T, I84L, L101I, S119P, T122I, T124A, T125A, K136Q, V165I, V201I, K211R, T218L, K219Q, L234V, D256E, S283G, D288NF
Canducci (2011)Pt11Pt11w12aJN163909RAL12Y143R S17N, A23V, V31I, M50I, L101I, T124A, T125A, K136L, V201I, L234V, D256EF
  Pt11w12bJN163910RAL14Y143RT97AS17N, A23V, V31I, M50I, L101I, T124A, T125A, K136L, V201I, L234V, D256EF
Garrido (2012)BAA295904BAA295904JQ716897RAL52  S17N, R20K, I72V, L101I, T112R, T124G, T125A, K136Q, F181L, G193D, V201I, T218I, L234I, D256E, D279G, S283GF
de Souza Cavalcanti (2014)BRSP271BRSP271 RAL G140S, Q148HG163DEKNE11D, S17N, L63V, L74I, I84L, L101I, K111R, I113L, S119P, T125A, V165I, V201I, T206S, L234V, D256E, S283GF
 BRSP308BRSP308 RAL  G163KE11D, S17N, V31I, I72V, I84L, A98G, L101I, S119T, T124A, T125A, K136Q, V201I, K211R, L234V, D256E, S283GF
 BRSP117BRSP117 RAL   S17N, L45Q, I84L, L101I, K111R, S119T, T124TA, T125A, K136Q, V165I, V201I, A205S, K211R, T218I, L234V, S255SN, D256E, R269K, S283G, D286NF
 BRSP522BRSP522 RAL   S17N, I72V, I84L, S119P, T122I, T124A, T125A, G163T, A205S, T206TS, S255SN, D256E, S283SGF