<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype D
Gene IN
Mutation T97A
Rx II-naive
IncludeMixtures No
References 6
Patients 10
Isolates 10
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Gao (1998)84ZR08584ZR085U88822None  T97AI72V, T112V, I113V, T124A, V201I, T206S, K211R, L234ID
Dowling (2002)KER2017KER2017AF457056None  T97AE11D, N27G, M50I, I72V, L101I, T112I, I113V, T124A, T125A, K136Q, D167E, V201I, L234I, S283GD
Brennan (2008)ABB21-96ABB21-96EU618508None  T97AD6S, E10ED, E13D, V32I, I72V, L101I, K103N, T112V, I113V, T125A, V126M, K160R, V201I, L234I, D279G, R284GD
Monleau (2012)DRC-MBTDRC-MBTJQ250584None  L74M, T97AK14R, R20K, I72V, K111T, T112V, I113V, T124G, T125A, V165I, V201I, T218I, L234I, D256E, S283G, D288ND
 CIR CIRCIRCIRJQ250595None  T97AA23V, L28I, I72V, T112V, T124A, T125A, V126L, I135V, K160R, G163T, Q177H, F181L, V201I, T218I, L234I, A265V, D278A, C280VD
Hora (2015)DEURF09UG004DEURF09UG004KF716481None  T97AS17N, S39N, M50L, I72V, T112V, I113V, T124A, T125A, V201I, L234V, D256ED
 DEURF10UG011DEURF10UG011KF716482None  T97AK14R, I60M, I72V, L101I, T112V, I113V, T124A, T125A, V126F, K173R, I182V, V201I, S283GD
 DEURF09UG002DEURF09UG002KF859746None  T97AS17N, K34R, M50L, I72V, I84M, T112V, I113V, T124A, T125A, V201I, S283GD
Billings (2016)KE956490V3KE956490V3KT022398None  T97AS17N, N27G, P30H, M50L, L74I, L101I, T112V, I113V, T124A, T125A, G134D, K188R, V201I, N222K, L234I, D256E, I268L, S283GD
 KE897156V5KE897156V5KT022409None  T97A, G163RS17N, L101I, T112V, I113V, T124A, K156H, V165I, K188R, V201I, S255N, I268L, V281M, S283GD