<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype D
Gene IN
Mutation L74M
Rx II-naive
IncludeMixtures No
References 4
Patients 4
Isolates 4
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Koulinska (2002)TZBFL0011TZBFL0011AF442569None  L74MS17N, M50L, I72V, G106R, T112V, I113V, T124A, T125A, D167E, V201I, L234I, D256E, A265V, S283GD
Brennan (2008)336-39336-39EU618153None  L74ME10D, K14R, I72V, A91E, T112V, I113V, S119R, T122I, T124A, T125A, V201I, K211R, T218I, L234I, R284GD
Monleau (2012)DRC-MBTDRC-MBTJQ250584None  L74M, T97AK14R, R20K, I72V, K111T, T112V, I113V, T124G, T125A, V165I, V201I, T218I, L234I, D256E, S283G, D288ND
Billings (2016)CO3016V6CO3016V6KX907359None  L74MS17N, R20K, F100Y, L101I, T112V, T124A, T125A, F181L, V201I, K211R, L234I, A265V, D278A, S283G, R284GD