<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype D
Gene IN
Mutation L74I
Rx II-naive
IncludeMixtures No
References 5
Patients 7
Isolates 7
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Couto-Fernandez (2006)patient_05BRRJ09505BRRJ095DQ138974None   E10D, R20K, I72V, L74I, I84V, P90A, G106A, T112M, T124A, T125A, G193E, V201I, D207N, K211Q, L234I, N254KD
 patient_04BRRJ13504BRRJ135DQ138976None   K14R, S24N, I72V, L74I, T112V, I113A, T124A, T125A, V201I, L213FD
 patient_98BRRJ04598BRRJ045DQ141207None   S17N, L45Q, I72V, L74I, T112V, I113V, T124S, T125A, V201I, A205S, N222H, L234ID
Van Laethem (2008)AR04-342AR04-342EU882762None   E11D, S24N, N27G, L74I, L101I, T112V, I113V, T124A, V201I, T206S, D207E, T218TI, R224Q, L234T, S255S_G, I268V, D270ND
Yamaguchi (2008)J11245J11245EU697911None   S17N, V31I, M50L, L74I, T112I, I113V, T124N, T125A, G163E, D167E, V201I, T206S, L234I, D256ED
Billings (2016)KE956490V3KE956490V3KT022398None  T97AS17N, N27G, P30H, M50L, L74I, L101I, T112V, I113V, T124A, T125A, G134D, K188R, V201I, N222K, L234I, D256E, I268L, S283GD
Inzaule (2018)UGJFPPM195UGJFPPM195MG694078None   S17N, I60L, I72V, L74I, V88A, L101I, T112V, I113V, S119P, T124A, T125V, D167E, K173R, V201I, L234I, N254Q, S255G, A265VD