<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype D
Gene IN
Mutation T206S
Rx II-naive
IncludeMixtures No
References 13
Patients 19
Isolates 19
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Gao (1998)84ZR08584ZR085U88822None  T97AI72V, T112V, I113V, T124A, V201I, T206S, K211R, L234ID
Arroyo (2004)01TZA28001TZA280AY253311None   E11D, K14R, P30S, S39C, I72V, L101I, T112V, T124A, K156R, V201I, T206S, I208L, K211T, L234I, N254H, M275VD
Fang (2004)ML415_2_1997415_2_1997AY322189None   S17N, I72V, I84M, L101I, T112I, I113V, T124A, T125A, I135V, M154T, V201I, T206S, T218I, L234I, I251L, D256ED
Tovanabutra (2005)99US_MSC406899US_4068AY444799None   S17N, M50L, I72V, T112I, I113V, T124A, T125A, V201I, A205S, T206S, L234I, D256E, S283GD
Brennan (2008)33-3333-33EU618152None   D6S, E10D, E13D, V32I, I72V, T112V, I113V, T124A, V201I, T206S, Y227F, L234I, S255N, D256E, S283SGD
Yamaguchi (2008)J11245J11245EU697911None   S17N, V31I, M50L, L74I, T112I, I113V, T124N, T125A, G163E, D167E, V201I, T206S, L234I, D256ED
Eshleman (2009)326.57326.57FJ480238None   S17SN, R20K, I72V, T112V, I113V, S119T, T124A, T125A, K156KN, E157EQ, G163GV, V201I, T206S, K211KR, T218I, L234I, A265AVD
Garrido (2009)178INT-178GU217025None   K14R, S39C, I72V, T112V, I113V, T124A, D167E, V201I, T206S, L234I, K264KND
 245INT-245GU217092None   K14R, S17N, V31I, K71Q, I72V, T112V, I113V, S119R, T124AS, T125S, I135IV, K173R, K188R, V201I, T206S, L234I, A265VD
Sichtig (2009)60-E60-EFJ183634None   K34R, I60IM, I72V, I84M, T112V, I113V, S119P, T124A, T125A, I182IV, V201I, T206S, I208L, K211Q, L234ID
van Hal (2009)W15W15FJ554688None   V31I, S57C, I72V, L101I, S119G, T122I, T124A, E152K, K188R, G193E, V201I, T206S, K211R, R231K, A265VD
 W63W63FJ554736None   S17N, V31I, S57C, I72V, L101I, S119G, T122I, T124A, E152K, K188R, G193E, V201I, T206S, K211R, R231K, A265VD
Tovanabutra (2010)KECst_015KECst_015FJ623490None   S17N, I72V, T112V, I113V, T124A, T125A, G134D, D167E, G193D, T206S, L234I, S255N, R269K, D270H, D278A, S283GD
 KECst_01414-strain2FJ623495None   S17N, L101V, T112V, T124A, T125A, V201I, T206S, T218I, L234I, D256E, A265V, R269KD
Monleau (2012)SK1002SK1002JQ250540None   S24G, I72V, T112V, I113V, T124A, T125A, K188KR, V201I, T206S, K211KR, L234I, A265AV, I268IL, D270H, S283GD
Reigadas (2013)602602JX425847None   K14R, S24H, I72V, L101I, T112V, S119P, T124A, I135V, K136Q, K173R, V201I, T206S, K215R, T218I, L234I, D256E, S283GD
 701701JX425868None   K7R, S17N, I72V, I84M, L101I, T112I, I113V, S119P, T124A, K136Q, K173R, V201I, T206S, I208L, Y227F, L234I, D256ED
 703703JX425870None   D3E, D6N, K7E, E13D, L101I, G106GA, T112V, I113V, S119T, T124A, T125TA, E157Q, K160Q, V201I, A205AS, T206S, D207DE, Y227F, L234I, A265V, S283GD
 708708JX425875None   S17N, K34R, I72V, T112A, I113V, T124A, I141V, K188R, S195T, V201I, T206S, L234ID