<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype D
Gene IN
Mutation T206S
Rx II-naive
IncludeMixtures No
References 18
Patients 39
Isolates 39
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Gao (1998)84ZR08584ZR085U88822None  T97AI72V, T112V, I113V, T124A, V201I, T206S, K211R, L234ID
Dowling (2002)KISII5003KISII5003AF457059None   D3E, K14R, S17N, M50L, I72V, T112V, I113V, S119P, T124A, T125A, V201I, T206S, I208L, K219N, N222K, L234I, D256E, S283GD
Arroyo (2004)01TZA28001TZA280AY253311None   E11D, K14R, P30S, S39C, I72V, L101I, T112V, T124A, K156R, V201I, T206S, I208L, K211T, L234I, N254H, M275VD
Fang (2004)ML415_2_1997415_2_1997AY322189None   S17N, I72V, I84M, L101I, T112I, I113V, T124A, T125A, I135V, M154T, V201I, T206S, T218I, L234I, I251L, D256ED
Tovanabutra (2005)99US_MSC406899US_4068AY444799None   S17N, M50L, I72V, T112I, I113V, T124A, T125A, V201I, A205S, T206S, L234I, D256E, S283GD
Brennan (2008)33-3333-33EU618152None   D6S, E10D, E13D, V32I, I72V, T112V, I113V, T124A, V201I, T206S, Y227F, L234I, S255N, D256E, S283SGD
Van Laethem (2008)AR04-342AR04-342EU882762None   E11D, S24N, N27G, L74I, L101I, T112V, I113V, T124A, V201I, T206S, D207E, T218TI, R224Q, L234T, S255S_G, I268V, D270ND
Yamaguchi (2008)J11245J11245EU697911None   S17N, V31I, M50L, L74I, T112I, I113V, T124N, T125A, G163E, D167E, V201I, T206S, L234I, D256ED
Eshleman (2009)326.57326.57FJ480238None   S17SN, R20K, I72V, T112V, I113V, S119T, T124A, T125A, K156KN, E157EQ, G163GV, V201I, T206S, K211KR, T218I, L234I, A265AVD
Garrido (2009)178INT-178GU217025None   K14R, S39C, I72V, T112V, I113V, T124A, D167E, V201I, T206S, L234I, K264KND
 245INT-245GU217092None   K14R, S17N, V31I, K71Q, I72V, T112V, I113V, S119R, T124AS, T125S, I135IV, K173R, K188R, V201I, T206S, L234I, A265VD
 401INT-401GU217248None   E10D, M22ML, M50L, I72V, T112V, I113V, T124A, K188KR, V201I, T206S, R231RK, L234I, A265V, D278DA, R284G, D286ND
Sichtig (2009)60-E60-EFJ183634None   K34R, I60IM, I72V, I84M, T112V, I113V, S119P, T124A, T125A, I182IV, V201I, T206S, I208L, K211Q, L234ID
Tovanabutra (2010)KECst_015KECst_015FJ623490None   S17N, I72V, T112V, I113V, T124A, T125A, G134D, D167E, G193D, T206S, L234I, S255N, R269K, D270H, D278A, S283GD
 KECst_01414-strain2FJ623495None   S17N, L101V, T112V, T124A, T125A, V201I, T206S, T218I, L234I, D256E, A265V, R269KD
Monleau (2012)SK1002SK1002JQ250540None   S24G, I72V, T112V, I113V, T124A, T125A, K188KR, V201I, T206S, K211KR, L234I, A265AV, I268IL, D270H, S283GD
Reigadas (2013)701701JX425868None   K7R, S17N, I72V, I84M, L101I, T112I, I113V, S119P, T124A, K136Q, K173R, V201I, T206S, I208L, Y227F, L234I, D256ED
 703703JX425870None   D3E, D6N, K7E, E13D, L101I, G106GA, T112V, I113V, S119T, T124A, T125TA, E157Q, K160Q, V201I, A205AS, T206S, D207DE, Y227F, L234I, A265V, S283GD
 705705JX425872None   S17N, D25E, P30A, D41N, L45I, L101I, T112V, I113V, S119T, T125A, E157Q, K160Q, G163E, V201I, T206S, L234ID
 708708JX425875None   S17N, K34R, I72V, T112A, I113V, T124A, I141V, K188R, S195T, V201I, T206S, L234ID
Hora (2015)DEURF10UG012DEURF10UG012KF716483None   K14R, V31I, V75I, I84M, L101I, T112V, I113V, T124A, T125A, V201I, T206S, T218I, L234I, I251L, D256E, A265V, D279GD
 DEURF09UG005DEURF09UG005KF859747None   S17N, I72V, T112V, I113V, T124A, T125A, Q177L, V201I, T206S, L234I, D256E, V260ID
 DEURF11UG004DEURF11UG004KF716484None   K14R, S17N, I72V, L101I, T112V, I113V, T124A, T125A, V165I, V201I, T206S, L234I, I268L, S283GD
 DEURF09GQ001DEURF09GQ001KC473845None   K14R, R20K, A23V, S24G, F26Y, N27X, M50I, I72V, T112V, I113V, T124G, T125A, V201I, T206S, L234I, D256E, D279G, R284GD
Pessoa (2015)10BR_MG010MG010KJ849787None   E11D, S17N, A23V, L28I, P30A, M50I, I72V, A91T, L101I, T124A, K136Q, V165I, V201I, T206S, L234V, S283GD
Billings (2016)KE961896V5KE961896V5KT022410None   K14R, S17N, M50L, L101I, T112V, S119P, T122I, T124A, T125S, I135V, K136Q, V165I, F185Y, V201I, T206S, K215R, I220V, L234ID
Inzaule (2018)UGMBAPM172UGMBAPM172MG694103None   S17N, V31I, M50I, I72V, Y99F, T112V, I113V, S119T, T124A, T125A, V201I, T206S, S230N, L234I, N254H, D256ED
 UGMBAPM106UGMBAPM106MG694096None   I72V, L101I, T112V, I113V, S119T, T125V, V201I, T206S, I208L, K211T, T218I, N222K, L234I, N254Q, A265V, M275VD
 UGMBAPM078UGMBAPM078MG694092None   S17N, R20K, M50L, I72V, L101I, T112V, I113V, T124A, G193D, S195C, V201I, T206S, L234V, D256E, I268L, D270H, S283GD
 UGMBAPM045UGMBAPM045MG694088None   S17N, M50L, I72V, T112V, I113V, T124A, T125A, F181L, V201I, T206S, L234I, D256ED
 UGJFPPM181UGJFPPM181MG694076None   D6E, E11D, V37I, M50I, I72V, T112V, I113V, S119T, T124G, T125A, V201I, T206S, L234I, N254H, R284GD
 UGJFPPM036UGJFPPM036MG694059None   S17N, M50L, I72V, L101I, T112V, I113V, T124A, V201I, T206S, T210I, K211R, T218I, L234I, D256E, A265VD
 UGJCRPM134UGJCRPM134MG694037None   K14R, S17N, M50L, I72V, T112V, I113V, S119P, T124A, T125A, K156N, V201I, T206S, T210I, Q214E, T218I, L234V, D256E, D278N, S283GD
 UGJCRPM052UGJCRPM052MG694019None   S17N, I72V, T112V, I113V, S119P, T124A, T125A, I141V, V201I, T206S, T218I, L234I, S283GD
 UGJCRPM044UGJCRPM044MG694016None  G163KS17N, L101I, K103R, T112V, I113V, T124S, T125A, K156N, Y194C, V201I, T206S, K211N, L234I, D256E, I268L, D270HD
 UGJCRPM035UGJCRPM035MG694011None   S17N, I72V, P90A, L101I, T112V, I113V, S119P, T124A, T125A, K160N, V201I, T206S, I208L, E212H, L234I, N254HD
 SAMMHPM147SAMMHPM147MG693961None   K14R, M50L, L101I, T112V, T124A, T125A, D167E, G193R, V201I, T206S, L234I, D256E, A265V, S283GD
 KEMATPM102KEMATPM102MG693850None   S17N, M50L, L101I, T112V, S119G, T122I, T124A, T125A, G134D, V201I, T206S, L234I, D256E, I268L, D279GD
 KECRHPM133KECRHPM133MG693814None   K14R, I72V, T112V, I113V, T124A, T125A, G193R, V201I, T206S, L234I, A265VD