<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype D
Gene IN
Mutation E157Q
Rx II-naive
IncludeMixtures No
References 6
Patients 10
Isolates 10
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Kijak (2004)4412HAL01CM.4412AY371157None   D6S, K7E, E10D, E11D, E13D, V31I, V32I, I72V, A91S, T112V, I113V, T124A, T125A, K156N, E157Q, V201I, T218S, N222H, L234ID
 0908MO01CM.0908AY371170None   K14R, V31I, I72V, G82S, T112V, I113V, T124A, T125A, K156N, E157Q, V201I, L234I, D256E, V281M, S283GD
Van Laethem (2008)AR02-071AR02-071EU882758None   S17N, I72V, T112V, I113V, T124A, E157Q, K160N, V201I, T218TM, L234I, A265V, R284RGD
 AR01-109AR01-109EU882757None   S17N, I72V, T112V, I113V, T124A, E157Q, K160N, V201I, T218M, L234I, A265VD
Monleau (2012)SK1025SK1025JQ250544None   K14R, V31I, L45LI, I72IV, T112V, I113V, T124A, T125A, K156N, E157Q, D167E, V201I, K211R, Q221Q*, R224RW, L234I, L241LF, A265V, S283GD
Reigadas (2013)703703JX425870None   D3E, D6N, K7E, E13D, L101I, G106GA, T112V, I113V, S119T, T124A, T125TA, E157Q, K160Q, V201I, A205AS, T206S, D207DE, Y227F, L234I, A265V, S283GD
 705705JX425872None   S17N, D25E, P30A, D41N, L45I, L101I, T112V, I113V, S119T, T125A, E157Q, K160Q, G163E, V201I, T206S, L234ID
Billings (2016)KE543869V2KE543869V2KT022385None   E10K, S17N, M50L, I72V, L101I, T112V, I113V, T124G, T125A, E157Q, K160Q, F181L, V201I, K211R, T218I, L234I, A265V, I268LD
Inzaule (2018)UGJCRPM117UGJCRPM117MG694031None   S17N, L45I, M50L, L101I, T112I, T122I, T124A, T125A, K156N, E157Q, K188R, G193E, V201I, I268L, S283GD
 UGJCRPM096UGJCRPM096MG694027None   S17N, M50I, I72V, T112V, I113V, T124A, T125A, E157Q, K160Q, D167E, V201I, K211Q, T218I, L234I, A265VD