<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype D
Gene IN
Mutation T125V
Rx II-naive
IncludeMixtures No
References 6
Patients 10
Isolates 10
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Dowling (2002)KSM4015KSM4015AF457073None   M50L, I72V, T112V, I113V, T124A, T125V, V201I, Q216H, K219N, L234I, S283GD
Brumme (2009)F3507F3507GQ371866None   K7R, S17N, M50L, I72V, T112V, I113V, T125VD
Eshleman (2009)128.318128.318FJ480227None   S17N, M50L, I72V, L101I, T112V, I113V, T124A, T125V, V201I, T218I, L234I, L242X, D256E, A265VD
Cho (2013)04KBH804KBH8DQ054367None   K7E, E11D, D25E, S39C, L45Q, I72V, T112V, T124A, T125V, E157D, D167E, V201I, K211R, L234I, N254SD
Billings (2016)KE556528V2KE556528V2KT022389None   E11D, V37I, M50L, I72V, L101I, T112V, I113V, T124N, T125V, G134N, V165I, K173R, V201I, I220T, S283GD
Inzaule (2018)UGMBAPM233UGMBAPM233MG694108None   S17N, M50L, I72V, T112V, I113V, T125V, V165I, V201I, T218I, L234I, D256E, R269KD
 UGMBAPM106UGMBAPM106MG694096None   I72V, L101I, T112V, I113V, S119T, T125V, V201I, T206S, I208L, K211T, T218I, N222K, L234I, N254Q, A265V, M275VD
 UGMBAPM094UGMBAPM094MG694094None   S17N, M50L, I72V, I84L, T112V, I113V, T124A, T125V, V201I, T218I, N222K, L234I, D256E, A265VD
 UGJFPPM195UGJFPPM195MG694078None   S17N, I60L, I72V, L74I, V88A, L101I, T112V, I113V, S119P, T124A, T125V, D167E, K173R, V201I, L234I, N254Q, S255G, A265VD
 UGJCRPM186UGJCRPM186MG694046None   M50L, K111Q, T112V, I113V, T124A, T125V, V201I, T218I, K219N, N222K, L234ID