<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF02_AG
Gene IN
Mutation T97A
Rx II-naive
IncludeMixtures No
References 12
Patients 36
Isolates 38
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Kijak (2004)0015BBY02CM.0015AY371127None  T97AE11D, K14R, V31I, L101I, T112V, S119T, T124A, T125A, G134D, I135V, K136T, V201I, T206S, I208L, L234I, D286NCRF02_AG
 1970LE02CM.1970AY371128None  T97AK14R, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, R269K, S283GCRF02_AG
Njai (2006)MP57097CM.570AM279374None  L74M, T97AK14R, V31I, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234ICRF02_AG
Brennan (2008)1012-281012-28EU618063None  L74M, T97AK14R, V31I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, G163A, V201I, T206S, T218I, L234ICRF02_AG
 4455-74455-7EU618187None  L74M, T97AS17N, A91E, L101I, T112V, S119R, T124A, G134N, I135V, K136T, V201I, T206S, D207E, K211R, L234ICRF02_AG
 4560-204560-20EU618195None  L74IM, T97AK14R, K34R, I72V, L101I, T112V, T124G, T125A, G134D, I135V, K136T, V201I, T206S, L234I, M275V, S283GCRF02_AG
 4599-114599-11EU618196None  L74M, T97AE11D, K14R, V31I, S57SG, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, I220V, L234I, R269KCRF02_AG
 626-2626-2EU618267None  L74M, T97AS17SR, V31I, I72IV, L101I, T112V, T124A, T125TA, G134DN, I135IV, K136T, V201I, T206S, I208L, T218I, L234I, I251L, A265V, R269K, D286NCRF02_AG
 880-29880-29EU618319None  L74IM, T97AK14R, K34R, I72V, L101I, T112V, T124G, T125A, G134D, I135V, K136T, V201I, T206S, L234I, M275V, S283GCRF02_AG
 A1102A1102EU618346None  L74M, T97AE11D, V31I, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, R269KCRF02_AG
 A1222A1222EU618364None  T97AK14R, V31I, M50T, L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, A265V, R269K, S283G, D288NCRF02_AG
 A1265A1265EU618373None  T97AK14R, V31I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269K, S283GCRF02_AG
 A1267AA1267AEU618375None  T97AK14R, S17N, V31I, S57G, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K188R, V201I, T206S, L234I, A265V, S283GCRF02_AG
 A1373A1373EU618377None  T97AK14R, V31I, S57G, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I208L, T218I, L234I, S283GCRF02_AG
 A1760A1760EU618432None  T97AE11D, K14R, R20K, V31I, D41A, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K173R, V201I, T206S, L234I, S283GCRF02_AG
 A1772A1772EU618440None  L74M, T97AK14R, S24N, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218TI, L234I, R269KCRF02_AG
 A1802A1802EU618464None  T97AE11D, K14R, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, S283G, D288NCRF02_AG
 AB1076AB1076EU618475None  T97AV31I, M50I, L74I, L101I, T112V, S119G, T124A, T125A, G134N, I135V, K136T, F181L, V201I, T206S, T218I, L234I, A265V, R269K, S283G, D288NCRF02_AG
 ABB59-96ABB59-96EU618545None  L74M, T97AK14R, S24N, V31I, I72V, L101LI, T112V, T124A, T125A, G134N, I135V, K136T, G193GE, V201I, T206S, T218I, L234I, R269K, S283GCRF02_AG
 ABB87-96ABB87-96EU618572None  T97AK14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, K211R, T218I, I220IV, L234I, A265V, R269K, S283GCRF02_AG
 ABB99-97ABB99-97EU618584None  T97AK14R, V31I, A91E, L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, L234I, S283GCRF02_AG
Eshleman (2009) ABB99-97FJ480297None  T97AK14R, V31I, A91E, L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, L234I, S283GCRF02_AG
Sichtig (2009)17201720FJ183580None  T97AE11D, K14R, V31VI, S39C, L101I, T112V, T124A, T125A, G134N, I135V, K136KT, V165VI, F181Y, V201I, T206S, L234I, R269KCRF02_AG
Carr (2010)1970LE02CM.1970LEGU201511None  T97AK14R, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, R269K, S283GCRF02_AG
Kousiappa (2011)CY252CY252JF683795None  T97AK14R, V31I, A91E, L101I, T112I, S119R, T124S, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, Q216H, L234I, I268L, E287DCRF02_AG
Monleau (2012)DRA DRADRADRAJQ250604None  T97AK14R, V31I, V32I, S39M, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, Q137H, M154I, F181L, V201I, T206S, L234ICRF02_AG
Reigadas (2013)428428JX425761None  L74M, T97AK14R, S57G, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, K188R, V201I, T206S, T218I, L234I, A265V, R269K, S283G, D286NCRF02_AG
 484484JX425817None  T97AE11D, S17N, V31I, I72V, L74I, L101I, T112V, T124A, T125TA, G134N, K136T, Q137H, K160KHNQ, V201I, T206S, T218IL, I220IL, L234I, R269K, D286NCRF02_AG
Paolucci (2014)PV18_2008PV18_2008KJ612230None  T97AK14R, V31I, L101I, T112I, T124A, T125A, G134N, K136T, E157Q, V201I, A205S, T206S, L234ICRF02_AG
 PV27_2005PV27_2005KJ612240None  T97AK14R, K34R, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, I203M, T206S, L234ICRF02_AG
 PV18_2007PV18_2007KJ612229None  T97AK14R, V31I, M50T, L101I, T112I, T124A, T125A, G134N, K136T, V201I, A205S, T206S, L234ICRF02_AG
 PV27_2006PV27_2006KJ612241None  T97AK14R, K34R, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, I203M, T206S, L234ICRF02_AG
 PV10_2008PV10_2008KJ612214None  T97AK14R, V31I, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, S195T, V201I, T206S, I220L, L234I, D256YCRF02_AG
 PV10_2009PV10_2009KJ612215None  T97AK14R, V31I, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, S195T, V201I, T206S, I220L, L234I, D256YCRF02_AG
 PV18_2006PV18_2006KJ612228None  T97AK14R, V31I, M50T, E85K, L101I, T112I, T124A, T125A, G134N, K136T, E157Q, V201I, A205S, T206S, L234ICRF02_AG
 PV22_2011PV22_2011KJ612231None N155ST97AE11D, V31I, M50I, L101I, K111R, T112V, T124A, T125A, G134N, K136T, E157A, K159M, K160I, I162V, R166P, A175P, V201I, T206S, D207G, I208F, Q209P, K215N, L234ICRF02_AG
Hora (2015)DEURF07ES002DEURF07ES002JX140677None  T97AK14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, L234I, D256E, S283GCRF02_AG
Heipertz (2016)NG010325NG010325KX389624None  L74M, T97AH12HR, K14R, V31I, M50V, S57G, I60V, L101I, T112I, S119R, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, D256E, R269K, D278G, S283GCRF02_AG