<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF02_AG
Gene IN
Mutation I72V
Rx II-naive
IncludeMixtures No
References 24
Patients 128
Isolates 133
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Gao (1998)92NG00392NG003U88825None   E11D, K14R, V31I, I72V, L74I, T112V, T124A, T125A, V126M, G134N, K136Q, V201I, T206S, T218I, L234I, D256E, A265V, R269K, D278G, S283GCRF02_AG
Peeters (1999)97CA-MP645MP97CAAJ239083None T66AL74MK14R, V31I, I72V, I84V, L101I, T112I, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, V281A, D286NCRF02_AG
Mamadou (2003)97NE0397NE03AJ508595None   K14R, V31I, M50I, S57G, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, S283GCRF02_AG
Swanson (2003)DJ258DJ258AY214077None   K14R, V31I, S39C, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, N254Q, R269K, S283GCRF02_AG
Kijak (2004)0013BBY02CM.0013AY371125None  L74MK14R, I72V, E96D, L101I, K111R, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, M275V, D286NCRF02_AG
 0074NY01CM.0074AY371131None   E11D, K14R, A23V, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, F181L, V201I, T206S, T218I, L234I, A265V, S283GCRF02_AG
 0158ND01CM.0158AY371132None   K14R, A21T, V31I, I72V, L74I, L101I, T112V, S119P, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, R269KCRF02_AG
 0925MO01CM.0925AY371134None   E11D, A21T, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K186R, V201I, T206S, L234I, A265V, R269K, D270HCRF02_AG
 4082STN02CM.4082AY371141None   K14R, V31I, K71R, I72V, L101I, K111Q, T112V, T122I, T124A, T125A, G134D, V201I, T206S, L234I, S283GCRF02_AG
 2339SA02CM.2339AY371143None   V31I, I72V, E96D, T112V, T124A, T125A, V126M, G134N, K136Q, V201I, L234I, S283GCRF02_AG
Meloni (2004)DDJ362DDJ362AY521632None   S24N, V31I, V32I, I72V, L74I, T112V, T124A, T125A, G134N, I135V, K136T, V165I, D167E, V201I, T206S, L234I, D279G, S283GCRF02_AG
Carr (2005)PL0754PL0754DQ168578None   K14R, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D253H, D256E, A265V, R269K, S283GCRF02_AG
Toni (2005)01IC_PCI12301_PCI123AJ866557None   E11D, K14R, S24N, V31I, K42R, M50I, I72V, I84M, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I217V, T218S, L234I, D256E, S283GCRF02_AG
Njai (2006)MP137899CM.1378AM279380None Q148K K14R, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, A169AV, V201I, T206S, Y227F, L234ICRF02_AG
 MP101498CM.1014AM279381None   K14R, A21T, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, K215N, T218I, L234ICRF02_AG
 MP57397CM.573AM279385None   K14R, V31I, S57G, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234ICRF02_AG
Tatsumi (2006)GHNJ176GHNJ176AB231894None   K14R, V31I, M50I, I72V, L74I, T112V, I113V, T124A, T125A, V126M, G134D, K136Q, G163E, V165I, V201I, T206P, N222H, L234I, S283G, D288NCRF02_AG
 GHNJ193GHNJ193AB231897None   K14R, W19G, V31I, M50T, I72V, L74I, T112V, I113V, T124A, T125A, V126M, G134D, K136Q, G163E, V165I, V201I, E212A, N222H, L234I, S283G, D288NCRF02_AG
Badreddine (2007)J11456SB_J11456DQ375272None   K14R, S57G, I72V, E96D, L101I, T112V, T124A, T125V, G134N, I135V, K136T, E157Q, V201I, T206S, D232E, L234I, D256E, S283GCRF02_AG
Brennan (2008)1055-71055-7EU618067None   E11D, K14R, S17SC, A23AV, S24SN, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, D286NCRF02_AG
 190-3190-3EU618112None   K14R, V31VI, S57G, I72V, L101I, T112V, T124A, T125V, G134N, I135V, K136T, V201I, T206S, I208L, L234I, S283GCRF02_AG
 191-48191-48EU618114None   K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, F181L, V201I, T206S, T218I, L234I, S283GCRF02_AG
 218-16218-16EU618118None   E11D, S17C, V31I, I72V, L101I, T112V, T124A, T125A, G134DN, I135V, K136T, D167E, V201I, T206S, T218I, L234I, R269K, S283G, D288NCRF02_AG
 255-09255-09EU618129None   K14R, R20K, V31I, M50L, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, S283GCRF02_AG
 27-1827-18EU618135None   K14R, V31I, S57G, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, R269K, D286NCRF02_AG
 3587-73587-7EU618157None  L68VK14R, S24N, I72V, L101I, T112I, T124A, T125A, G134N, I135V, K136T, K173R, V201I, T206S, T218I, L234I, A265V, S283SGCRF02_AG
 38-338-3EU618164None  L74MK14R, R20K, V31I, M50V, I72V, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, I208L, L234V, R269K, S283GCRF02_AG
 4191-144191-14EU618177None   E11D, K14R, R20K, V31I, S57G, I72V, E96D, L101I, T112I, T124A, T125A, G134N, I135V, K136T, D167E, V201I, T206S, L234I, S283GCRF02_AG
 4215-174215-17EU618178None   K14R, A21T, V31I, I72V, L74I, I84M, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157N, V201I, T206S, T218I, L234I, D256ECRF02_AG
 4560-204560-20EU618195None  L74IM, T97AK14R, K34R, I72V, L101I, T112V, T124G, T125A, G134D, I135V, K136T, V201I, T206S, L234I, M275V, S283GCRF02_AG
 4843-24843-2EU618209None   K14R, V31I, I72V, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, K160Q, V201I, T206S, L234I, A265V, R269K, S283GCRF02_AG
 49-2149-21EU618213None   K14KR, V31I, I72V, L101I, T112V, S119P, T122I, T124A, T125A, G134N, K136T, D167DE, V201I, T206S, T218I, L234I, A265V, R269K, D278A, S283GCRF02_AG
 5222-3B5222-3BEU618227None   K14R, A21T, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157N, V201I, T206S, T218I, L234I, D256ECRF02_AG
 551-20551-20EU618241None   V31I, M50T, I72V, L101I, T112V, S119G, T122I, T124A, T125A, G134N, I135V, K136T, K188R, V201I, T206S, L234I, I251L, S283GCRF02_AG
 5683-335683-33EU618249None   E11D, V31I, I72V, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, D207DE, T218I, L234I, R269K, S283GCRF02_AG
 577-11577-11EU618253None   K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, A265V, S283GCRF02_AG
 5787-35787-3EU618256None   E11D, K14R, S24N, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, K160Q, V201I, T206S, L234I, A265V, S283GCRF02_AG
 69-2469-24EU618281None   K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T218I, S230SN, L234I, A265V, S283GCRF02_AG
 707-45707-45EU618286None   E11D, K14R, V31I, L45Q, S57G, I72V, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I217V, T218I, L234I, S283GCRF02_AG
 88-2088-20EU618317None  L68VK14R, V31I, S57G, I72V, L101I, T112V, T124A, T125A, G134N, K136T, D167E, V201I, T206S, T218I, L234I, A265V, R269K, D286NCRF02_AG
 912-1912-1EU618326None   K14R, V31I, I72V, L101I, T112IV, G134N, K136T, V201I, T206S, L234I, R269K, S283GCRF02_AG
 A1098A1098EU618343None   E11D, K14R, V31I, I72V, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Q216H, L234I, R269K, S283GCRF02_AG
 A1149A1149EU618353None  V151VLE11D, V31I, S57G, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, R269K, S283GCRF02_AG
 A1152A1152EU618356None   K14R, K34R, I72V, L101I, T112V, S119P, T124A, T125A, G134N, I135V, K136T, D167E, V201I, T206S, L234I, S283GCRF02_AG
 A1186A1186EU618359None   K14R, S17N, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, G193D, S195C, V201I, T206S, L234I, I251IL, R269RK, D270H, S283G, D288NCRF02_AG
 A1220A1220EU618362None  T97AK14R, V31I, M50I, I72V, L74I, T112V, T125A, V126M, K136Q, E157Q, V201I, T206S, Q221Q*R, L234I, R269K, S283GCRF02_AG
 A1263A1263EU618371None   K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S283GCRF02_AG
 A1266A1266EU618374None  L74MK14R, V31I, I72V, I84V, P90S, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, R269K, S283GCRF02_AG
 A1381A1381EU618380None   K14R, V31I, S57G, I72V, K111R, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283GCRF02_AG
 A1393A1393EU618386None  L74IM, T97TAK14R, V31I, I72V, L101LI, T112V, T124A, T125A, G134N, I135IV, K136T, V201I, T206S, L234I, R269KCRF02_AG
 A1398A1398EU618388None  L74LMK14R, V31I, I72V, T112V, S119P, T122I, T124A, T125A, V126M, A133T, G134N, I135V, K136T, R187K, K188R, V201I, T206S, L234ICRF02_AG
 A1576A1576EU618393None   E11D, S24N, V31I, I72V, L101I, K111KR, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, R269K, S283GCRF02_AG
 A1612A1612EU618399None  L68VK14R, S24N, V31I, I72V, L101I, T112I, T124A, T125A, G134N, I135V, K136T, K173R, V201I, T206S, T218I, L234I, A265V, S283GCRF02_AG
 A1617A1617EU618403None   E11D, K14R, S24N, V31I, L45Q, I72V, E96D, L101I, T112IV, T124A, T125A, G134N, I135V, K136T, V201I, T218I, L234I, S283GCRF02_AG
 A1660A1660EU618414None   V31I, I72V, L74I, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, R269K, D278N, S283GCRF02_AG
 A1751A1751EU618424None   K14R, A21T, V31I, I72V, L74I, E96ED, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Q221T, L234I, D256E, R269KCRF02_AG
 A790A790EU618469None   E11D, K14R, A21T, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167E, V201I, T206S, L234I, R269KCRF02_AG
 ABB06-96ABB06-96EU618495None   E11D, K14R, A21T, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, L234I, R269K, M275VCRF02_AG
 ABB07-96ABB07-96EU618496None   K14R, I72V, L74I, L101I, T112V, T124A, G134N, K136T, G163E, V201I, T206S, L234I, R269KCRF02_AG
 ABB19-96ABB19-96EU618506None   K7R, E11D, K14R, V31I, I72V, L74I, I84V, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, R269K, D286NCRF02_AG
 ABB22-96ABB22-96EU618509None   E11D, K14R, V31I, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, A265AV, R269KCRF02_AG
 ABB23-96ABB23-96EU618510None  L74MK14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, R269K, D286NCRF02_AG
 ABB59-96ABB59-96EU618545None  L74M, T97AK14R, S24N, V31I, I72V, L101LI, T112V, T124A, T125A, G134N, I135V, K136T, G193GE, V201I, T206S, T218I, L234I, R269K, S283GCRF02_AG
 ABB74-96ABB74-96EU618559None   R20K, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, S283GCRF02_AG
 ABB80-96ABB80-96EU618565None  L74MV31I, I72V, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, A265V, R269K, D286NCRF02_AG
 ABB82-96ABB82-96EU618567None   E10D, K14R, R20K, V31I, M50I, I72V, Q95H, T112V, T124A, T125A, V126M, I135V, K136Q, E157Q, K160Q, V201I, T206S, L234I, A265V, S283GCRF02_AG
 ABB89-96ABB89-96EU618574None   K14R, V31I, I72V, L74I, L101I, T112V, I113L, T124A, K136Q, H183Y, V201I, T206S, L234I, A265V, R269K, D286NCRF02_AG
 ABB94-96ABB94-96EU618579None   K14R, A21T, V31I, I72V, L74I, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269KCRF02_AG
 ABB162-98ABB162-98EU618604None   K14R, S17C, V31I, I72V, L74I, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, L234I, A265V, R269K, D286NCRF02_AG
 ABB163-98ABB163-98EU618605None   E11D, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269KCRF02_AG
Land (2008)ML1979ML1979EU110091None   S17N, V31I, M50I, I72V, T112V, T124A, T125A, K136Q, D167E, V201I, K219N, N222K, S283G, D288NCRF02_AG
Eshleman (2009)ABB06-96ABB06-96FJ480265None   E11ED, K14R, A21T, V31I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, L234I, R269K, M275MVCRF02_AG
 ABB07-96ABB07-96FJ480266None   K14R, I72V, L74I, L101I, T112V, T124A, G134N, K136T, G163E, V201I, T206S, L234I, R269RKCRF02_AG
 ABB028-96ABB028-96FJ480275None   K14R, V31I, I72V, L74I, P90PS, A98G, L101I, T112V, T124A, K136Q, V201I, T206S, L234I, R269K, D286NCRF02_AG
 ABB074-96ABB074-96FJ480289None   S17SN, R20K, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, S283GCRF02_AG
 ABB89-96ABB89-96FJ480292None   K14R, V31I, I72V, L74I, L101I, T112V, I113L, T124A, K136Q, V201I, T206S, L234I, A265V, R269K, D286NCRF02_AG
 ABB94-96ABB94-96FJ480294None   K14R, A21T, V31I, I72V, L74I, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269KCRF02_AG
 ABB119-98ABB119-98FJ480304None   K14R, V31I, S57G, I72V, I84M, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I208L, L234I, R269K, S283GCRF02_AG
 ABB163-98ABB163-98FJ480310None   E11D, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269KCRF02_AG
Garrido (2009)48INT-48GU216895None   K14R, V31I, L63I, I72V, L74I, E96D, L101I, G106GA, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, R269KCRF02_AG
 202INT-202GU217049None   V31I, I72V, L74I, L101I, T112V, I113V, T124A, T125A, G134N, I135V, K136T, F181L, K188KR, V201I, T206S, T218TI, L234I, A265V, R269KCRF02_AG
Sichtig (2009)25-E25-EFJ183548None   K14R, V31I, L45LQ, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, Q221K, L234ICRF02_AG
 10661066FJ183578None   I72V, V77VI, I84M, L101I, T112V, S119P, T124A, T125A, G134D, I135V, K136T, F181Y, V201I, T206S, L234I, R269KCRF02_AG
 15141514FJ183579None   D41N, I72V, I84M, L101I, K103N, T112V, S119P, T124A, T125A, G134D, I135V, K136T, F181Y, V201I, T206S, L234I, R269KCRF02_AG
 38533853FJ183611None  L74LMK14R, S24SN, V31I, I72V, Q95QP, E96ED, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218TI, L234I, S255SG, D256DE, A265VCRF02_AG
 Pt064901FJ183627None   S17N, V31I, M50MI, I72V, L74I, L101I, T112V, I113L, T124A, T125A, G134D, I135V, V201I, T206S, L234ICRF02_AG
Avi (2010)N41N41GQ926787None   K14R, S24N, V31I, L45Q, I72V, L74I, T112V, I113V, T124S, T125A, G134N, K136Q, T206S, T218I, L234I, D256E, S283G, D286NCRF02_AG
Carr (2010)0144ND01CM.0144NDGU201495None   K14R, A21T, V31I, I72V, L74I, L101I, T112V, S119P, T122I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, Q221S, L234I, R269KCRF02_AG
Brenner (2011)120NB120NBHQ207720None   K14R, S24H, I72V, T112V, I113V, T124A, T125A, G134N, K136KT, V165I, V201I, T206S, L234I, D270N, S283SGCRF02_AG
Kim (2011)p51p51HM051467None   E11D, K14R, S24H, V32I, S39C, I72V, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, S255N, S283GCRF02_AG
Monleau (2012)SK1018SK1018JQ250515None   K14R, V31I, S39C, I72V, K111KR, T112V, T124A, T125A, G134N, I135V, K136T, S195ST, V201I, T206S, L234I, I251IL, S255T, A265AITV, R269RK, D270DN, S283GCRF02_AG
 SK4047SK4047JQ250521None   E11D, K14R, S24N, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157EQ, K160KQ, V201I, T206S, T218TI, L234I, R269K, V281VM, S283G, D286ECRF02_AG
 SK5013SK5013JQ250542None   K14R, R20K, V31I, M50I, I72V, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234I, S255N, D256E, A265AV, I267IV, I268IV, R269RK, S283GCRF02_AG
 VIA VIAVIA VIAJQ250598None   K14R, V31I, I72V, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, L234ICRF02_AG
 BUI BUIBUI BUIJQ250600None   K7R, E11D, R20K, S24N, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, N222K, L234TCRF02_AG
 LEF LEFLEF LEFJQ250601None   E11D, S24T, V31I, I72V, L101V, T112V, S119P, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234ICRF02_AG
 WIL WILWIL WILJQ250603None   E11D, E13D, S17T, A23V, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234ICRF02_AG
 DRA DRADRA DRAJQ250604None  T97AK14R, V31I, V32I, S39M, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, Q137H, M154I, F181L, V201I, T206S, L234ICRF02_AG
 MAU MAUMAU MAUJQ250605None  T97A, G140EE13K, K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E152K, M154I, V201I, T206S, L234ICRF02_AG
 NSI NSINSI NSIJQ250606None   K14R, S24N, V31I, I72V, L101I, T112V, T124A, T125A, G134S, I135V, K136T, V201I, T206S, L234ICRF02_AG
Oliveira (2012)GA08GA08JQ670795None   E11D, D25E, F26Y, V31VI, V37I, I72V, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, M275MV, D279G, S283GCRF02_AG
Parczewski (2012)26_5 H26_5 HKC409152None   E11D, D25E, V31I, I72V, Y99F, L101I, K103KR, K111KT, S119P, T122I, T124A, T125A, G134N, I135V, K136T, R187K, K188R, I200L, V201I, T206S, L234I, S255N, R269K, S283GCRF02_AG
Reigadas (2013)341341JX425462None   K14R, S17N, D25DE, V31I, M50MI, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, G163GE, D167DE, V201I, T206S, L234I, S283G, D288NCRF02_AG
 4949JX425517None   K14R, R20K, S57G, I72V, L101I, T124A, T125A, G134N, I135V, K136T, G149A, V201I, T206S, Y227F, L234I, S255N, S283GCRF02_AG
 109109JX425577None   D6E, E11D, E13D, V31I, V32I, K42R, I60V, L63LV, I72V, L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, H171L, F181L, I203M, L234I, D256E, S283GCRF02_AG
 402402JX425735None   E11ED, K14R, S24N, V31I, I72V, L101I, T112V, T124G, T125A, G134N, I135V, K136T, E157Q, K160KT, V201I, T206S, L234I, R269KCRF02_AG
 404404JX425737None   K14R, V31I, I72V, T93S, L101I, K111E, T112K, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D270E, S283GCRF02_AG
 420420JX425753None   L2LS, E11D, K14R, S24N, V31I, A49P, M50MT, I72V, E96D, L101I, T112M, T124A, T125A, G134N, K136T, Q137H, D167E, R187K, Y194YF, S195SHNR, V201I, T206S, Q216N, T218I, L234I, D256E, S283GCRF02_AG
 423423JX425756None   K14R, S24G, I72V, T112V, T124A, T125A, V126M, G134D, I135V, G163A, V201I, T206S, L234I, S283GCRF02_AG
 446446JX425779None   K14R, V31I, S57G, I72V, T112V, T124A, T125A, V126L, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283GCRF02_AG
 451451JX425784None   K14R, S24N, V31I, M50I, I72V, E96D, L101I, T112I, T124A, T125V, K127R, G134N, I135V, K136T, V201I, T206S, L234I, V260I, S283GCRF02_AG
 458458JX425791None   K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E157Q, K160Q, V201I, I203M, T206S, K219N, N222K, L234I, A265V, R269KCRF02_AG
 459459JX425792None   V31I, M50I, I72V, L101I, T112V, T125V, G134N, K136T, V201I, T206S, L234I, I268L, S283GCRF02_AG
 462462JX425795None   K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, F181L, V201I, T206S, K211R, T218I, L234I, N254S, S255G, A265V, R269K, S283GCRF02_AG
 464464JX425797None   K14R, S17N, V31I, S57G, I72V, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Q209P, Q214P, T218I, L234I, D256E, S283GCRF02_AG
 466466JX425799None   K14R, V31I, L45Q, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, V281M, S283GCRF02_AG
 470470JX425803None   K14R, V31I, M50T, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, A265V, S283GCRF02_AG
 474474JX425807None   D6DN, E11ED, S17SN, L28I, L45Q, G70GE, I72V, S81SR, L101I, T112V, T122I, T124A, T125P, G134N, I135V, K136T, L172LF, V201I, T206S, K215N, T218I, L234I, D270E, D279G, S283GCRF02_AG
 479479JX425812None   E11D, K14R, S24N, V31I, I72V, V88VI, L101I, T112V, T122TI, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283GCRF02_AG
 480480JX425813None   K14R, V31I, I72V, L74I, L101I, T112V, I113L, T124A, T125A, G134N, I135V, K136T, V201VI, T206S, I208IL, L234I, D256E, R269KCRF02_AG
 484484JX425817None  T97AE11D, S17N, V31I, I72V, L74I, L101I, T112V, T124A, T125TA, G134N, K136T, Q137H, K160KHNQ, V201I, T206S, T218IL, I220IL, L234I, R269K, D286NCRF02_AG
 486486JX425819None   K14R, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136T, T206S, L234I, A265AV, S283GCRF02_AG
 488488JX425821None   K7R, K14R, V31I, I72V, L101I, T112V, S119P, T122I, T124A, T125A, G134NS, I135V, K136T, F139Y, V201I, T206S, L234I, R269K, S283GCRF02_AG
 494494JX425827None   E11D, K14R, V31I, M50I, S57G, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, Y227F, L234I, S255G, M275V, S283GCRF02_AG
 495495JX425828None   K14R, V31I, M50I, I72V, I84M, L101I, T112I, S119P, T124A, T125A, G134N, K136T, I141V, V201I, T206S, I208L, L234I, S283GCRF02_AG
 501501JX425834None   E11D, K14R, A21AT, V31I, V54VA, I72V, L101I, K111KT, T112M, S119G, T122TI, T124TS, T125A, G134N, I135V, K136T, Q137H, V201I, T206S, Q221T, D232E, L234I, R269KCRF02_AG
 506506JX425839None   I72V, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I208L, K215KE, T218L, Q221H, N222K, L234I, I251IT, R269K, S283G, D286NCRF02_AG
 509509JX425842None   K14R, V31I, D41N, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, F181L, V201I, T206S, L234I, S255N, R269K, S283GCRF02_AG
 755755JX425881None   K14R, R20K, V31I, I72V, L101LI, T112IV, I113IV, T124A, T125A, G134N, I135IV, K136T, V201I, T206S, L234I, D279DG, S283G, R284RGCRF02_AG
 101128101128JX451881None   K14R, V31I, V32I, D41N, S57G, I72V, L101I, K111R, T112V, T124A, T125A, G134N, I135V, K136T, K188R, V201I, T206S, L234I, R269K, S283G, D286NCRF02_AG
 101101101101JX451926None   E11D, K14R, V31I, I72V, Q95S, L101I, T112V, S119P, T124A, T125A, G134N, I135V, K136T, E157Q, V201I, T206S, L234I, A265V, R269K, S283GCRF02_AG
 4216542165JX451941None   E11D, K14R, V31I, I72V, L74I, L101I, T112V, I113V, T124A, T125A, G134D, I135V, G163E, V201I, T206S, K211N, E212K, L234I, N254K, R269K, S283GCRF02_AG
 100988100988JX451947None  L74IM, T97TAK14R, V31I, I72V, E96D, G106GA, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S283GCRF02_AG

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