<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF02_AG
Gene IN
Mutation G163E
Rx II-naive
IncludeMixtures No
References 6
Patients 13
Isolates 14
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Tatsumi (2006)GHNJ176GHNJ176AB231894None   K14R, V31I, M50I, I72V, L74I, T112V, I113V, T124A, T125A, V126M, G134D, K136Q, G163E, V165I, V201I, T206P, N222H, L234I, S283G, D288NCRF02_AG
 GHNJ193GHNJ193AB231897None   K14R, W19G, V31I, M50T, I72V, L74I, T112V, I113V, T124A, T125A, V126M, G134D, K136Q, G163E, V165I, V201I, E212A, N222H, L234I, S283G, D288NCRF02_AG
Brennan (2008)263-21263-21EU618133None   K7R, K14R, V31I, L74I, I84M, L101I, T112V, T124A, T125A, G134N, I135V, K136T, G163E, V201I, T206S, I208M, L234I, R269KCRF02_AG
 328-02328-02EU618150None   L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, I161L, G163E, V201I, T206S, L234I, S283GCRF02_AG
 528-5528-5EU618232None   K14R, V31I, M50I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, G163E, V201I, T206S, L234I, D256E, S283GCRF02_AG
 5554-45554-4EU618244None   K14R, S17N, V31I, L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, S153A, G163E, V201I, T206S, L234I, D256E, S283GCRF02_AG
 A1801A1801EU618463None   K7KR, E11D, K14R, V31I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, G163E, V201I, T206S, I220V, L234I, R269KCRF02_AG
 ABB07-96ABB07-96EU618496None   K14R, I72V, L74I, L101I, T112V, T124A, G134N, K136T, G163E, V201I, T206S, L234I, R269KCRF02_AG
 ABB93-96ABB93-96EU618578None  L74MK14R, L101I, T112V, T124A, G134N, I135V, K136T, G163E, V201I, T206S, L234I, D270NCRF02_AG
Eshleman (2009)ABB07-96ABB07-96FJ480266None   K14R, I72V, L74I, L101I, T112V, T124A, G134N, K136T, G163E, V201I, T206S, L234I, R269RKCRF02_AG
Brenner (2011)185NB185NBHQ207722None   K14R, V31I, L101I, T112V, T124N, T125A, G134N, I135V, G163E, S195T, V201I, T206S, L234I, S283GCRF02_AG
Monleau (2012)SK3002SK3002JQ250543None   K14R, S24H, V31VI, S39C, L101IV, T112V, T124N, T125A, G134N, G163E, D167E, V201I, T206S, I208L, K211KR, Q216H, I220IL, Q221S, L234ICRF02_AG
Reigadas (2013)450450JX425783None   K14R, S17N, V31I, L74I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, G163E, V201I, T206S, L234I, N254K, S255G, S283GCRF02_AG
 4216542165JX451941None   E11D, K14R, V31I, I72V, L74I, L101I, T112V, I113V, T124A, T125A, G134D, I135V, G163E, V201I, T206S, K211N, E212K, L234I, N254K, R269K, S283GCRF02_AG