<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF02_AG
Gene IN
Mutation M154I
Rx II-naive
IncludeMixtures No
References 4
Patients 7
Isolates 7
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Brennan (2008)A1573A1573EU618390None  G140EE11D, K14R, V31I, E48EK, S57G, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E152K, M154I, G193R, V201I, T206S, T218I, L234I, D256E, S283GCRF02_AG
 ABB179-98ABB179-98EU618610None   K14R, V31I, A98T, L101I, T112V, S119G, T122I, T124A, T125A, G134N, I135V, K136T, M154I, V201I, T206S, L234I, A265V, R269K, S283GCRF02_AG
Monleau (2012)ABO ABOABOABOJQ250599None   K14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, M154I, E157K, V201I, I203M, T206S, T218I, L234I, A265V, S283G, D288ICRF02_AG
 DRA DRADRADRAJQ250604None  T97AK14R, V31I, V32I, S39M, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, Q137H, M154I, F181L, V201I, T206S, L234ICRF02_AG
 MAU MAUMAUMAUJQ250605None  T97A, G140EE13K, K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, E152K, M154I, V201I, T206S, L234ICRF02_AG
Reigadas (2013)492492JX425825None   K14R, M22L, V31I, S39N, S57G, L101I, T112V, H114P, T124A, T125S, G134N, I135V, K136T, M154I, D167E, R187K, K188R, V201I, T206S, T218I, L234I, S283GCRF02_AG
Paolucci (2014)PV14_2010PV14_2010KJ612222None   E10D, R20K, L45Q, I72V, L74I, I84V, T112V, T125A, G134N, I135V, K136T, M154I, G163A, V201I, L234I, D256ECRF02_AG