<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation Q95H
Rx II-naive
IncludeMixtures No
References 11
Patients 41
Isolates 41
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Tovanabutra (2004)01THOUR609I01_609IAY358040None   K14R, A21T, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, L234I, S283GCRF01_AE
Isarangkura-Na-Ayuthaya (2010)AE-Int-42AE-Int-42HM150816None   K14R, V31VI, I72V, Q95H, T112V, T124A, T125A, G134N, K136Q, V201I, L234I, S283GCRF01_AE
 AE-Int-79AE-Int-79HM150823None   K14R, V31I, S39SN, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136Q, I141V, D167E, V201I, L234ICRF01_AE
 AE-Int-81AE-Int-81HM150824None   K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 AE-Int-403AE-Int-403HM150885None   E11D, K14R, A21T, V31I, V32I, I72V, Q95H, T112V, T125A, G134N, K136Q, D167E, V201I, L234I, D286E, D288ECRF01_AE
Nouhin (2011)403298KCT0403298GU289852None   K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283GCRF01_AE
 60VNR60GU289865None   K14R, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
Wilantho A (2011)511282511282JF928839None   K14R, A21T, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160T, D167E, V201I, L234I, S283G, R284GCRF01_AE
 901273901273JF928905None  E138DK14R, A21T, V31VI, S39N, I72V, Q95H, T112V, T125A, G134N, K136Q, D167E, V201I, Q216N, L234I, S283GCRF01_AE
 521315521315JF928847None   K14R, A21T, S39N, L45Q, I72V, Q95H, T112V, T125A, G134N, I135V, K136R, V201I, L234I, S283GCRF01_AE
 600332600332JF928854None  E138DK14R, A21T, V31I, S39N, I72V, Q95H, T112V, T125A, G134N, K136Q, D167E, V201I, Q216N, L234I, S283GCRF01_AE
 500187500187JF928830None   K14R, A21T, A23V, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, V126VM, G134N, I135V, K136R, V165I, V201I, L234I, D253E, D256E, S283GCRF01_AE
 SL111SL111JF928959None   K14R, A21T, A23V, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, E170L, V201I, T206S, L234I, S283GCRF01_AE
 621941621941JF928865None   K14R, A21T, V31I, S39N, I72V, I84IV, Q95H, L101V, T112V, T115TA, N117NS, T124A, T125A, G134N, I135V, K136R, V165I, D167E, K173R, V201I, I217V, L234I, S283GCRF01_AE
Luu (2012)IVVI01979IVVI01979JQ288863None   K14R, A21T, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136Q, V201I, L234I, D279DG, S283GCRF01_AE
 IVVI02063IVVI02063JQ288867None   A8AP, K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 IVVI07324IVVI07324JQ288891None   K14R, A21T, V31I, S39N, M50MV, I72V, Q95H, T112V, T124TA, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
Rolland (2012)AA005a06LAA005a06LJX446722None   K14R, A21T, V31I, M50L, I72V, Q95H, T112V, I113V, T124A, T125A, G134N, V165I, V201I, L234I, S283GCRF01_AE
 AA050a_WG2AA050a_WG2JX447285None   K14R, A21T, V31I, V32I, I72V, Q95H, T112V, T124A, T125A, G134N, K136Q, M154MT, D167E, V201I, L234I, S283GCRF01_AE
 AA070a_LH07AA070a_LH07JX447491None   K14R, A21T, V31I, S39N, I72V, Q95H, K103R, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, R187K, V201I, T206S, L234I, S283GCRF01_AE
 AA075a_WG2AA075a_WG2JX447538None   E11D, K14R, A21T, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I204L, K211R, L234I, S283GCRF01_AE
 AA084a_wg4AA084a_wg4JX447673None   K14R, S39N, I72V, Q95H, T112V, I113V, T124A, T125A, G134N, K136Q, V165I, D167E, V201I, L234I, I251IV, P261S, S283GCRF01_AE
 AA101a_WG1AA101a_WG1JX447936None   K14R, A21T, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, G193E, V201I, L234V, S283G, D286NCRF01_AE
Zeng (2012)CN1242CN1242JQ028238None   K14R, A21T, A23V, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 CN1257CN1257JQ028240None   K14R, A21T, A23V, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 CN1287CN1287JQ028246None   K14R, A21T, V31I, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160T, D167E, V201I, L234I, S283GCRF01_AE
 CN1320CN1320JQ028262None   K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283GCRF01_AE
 CN1350CN1350JQ028266None   K14R, R20K, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, K219R, L234I, S283GCRF01_AE
Kotaki (2013)PJ68PJ68KF735930None   K14R, A21T, V32I, A38P, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 SM11SM11KF735918None   V31I, I72V, Q95H, T112V, I113V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283DCRF01_AE
 SM26SM26KF735920None   K14R, A21T, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134D, I135V, D167E, V201I, L234I, S283GCRF01_AE
Li (2013)22162216JQ302684None   K14R, A21T, A23AV, V32I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283GCRF01_AE
 22532253JQ302716None   A21T, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283GCRF01_AE
 20072007JQ302549None   K14R, A21T, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 20602060JQ302584None   K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 22522252JQ302715None   A21T, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283GCRF01_AE
Reigadas (2013)302302JX425423None   K14R, A21T, A23V, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, K173R, V201I, L234I, S283GCRF01_AE
 303303JX425424None   K14R, A21T, A23V, D25DE, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136QR, V165I, K173R, V201I, T206S, L234I, S283GCRF01_AE
 325325JX425445None   K14R, A21T, V31I, S39N, I72V, Q95H, G106A, T112V, T124TA, T125A, V126L, G134N, I135V, K136R, V165I, V201I, L234I, S283GCRF01_AE
Nerrienet (2014)T0630085T0630085JN675729None   K14R, A21T, V31I, Q95H, L101V, T112V, T124A, T125A, G134N, I135V, K136R, G163GE, V165I, V201I, I220V, L234I, S283GCRF01_AE
 T0506285T0506285JN675727None   K14R, A21T, A23V, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V201I, L234I, I268IVCRF01_AE