<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation L74M
Rx II-naive
IncludeMixtures No
References 7
Patients 9
Isolates 9
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Sanders-Buell (2010)569M569MGQ477441None  L74MK14R, R20K, S39N, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, T218I, K219N, L234I, D256E, S283GCRF01_AE
An (2012)09LNA37909LNA379JX960603None  L74MK14R, A21T, N27G, S39N, L45Q, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G, D286NCRF01_AE
Rolland (2012)AA002a_LH13AA002a_LH13JX446668None  L74MK14R, V31I, S39N, D41N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, I141V, K160Q, D167E, R187K, V201I, L234I, V249I, D279A, S283G, R284G, D286NCRF01_AE
 AA131a01LAA131a01LJX448311None  L74MK14R, A21T, A23V, V31I, M50I, Q53K, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
Zeng (2012)CN0059CN0059JQ028201None  L74M, V151IK14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, H171Q, V201I, L234ICRF01_AE
 CN0918CN0918JQ028215None  L74MK14R, A21T, V32I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, K211R, L234I, V259I, S283GCRF01_AE
Kotaki (2013)PJ105PJ105KF735933None  L74MK14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
Li (2013)28192819JQ901035None  L74ME11D, K14R, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193E, V201I, L234I, D279G, S283GCRF01_AE
Li (2013)21572157JQ302642None  L74MK14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, H171Y, V201I, L234I, S283GCRF01_AE