<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation L68I
Rx II-naive
IncludeMixtures No
References 7
Patients 9
Isolates 9
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Kijak (2004)0190MA01CM.0190AY371145None  L68IE11D, K14R, V31I, D41N, M50I, I72V, L101I, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, T206S, T218I, L234I, S283G, D288NCRF01_AE
Liao (2009)VNAG22097VNAG220FJ185256None  L68IK14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
 VNAG22197VNAG221FJ185257None  L68IK14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283GCRF01_AE
Nouhin (2011)49KC49GU289829None  L68IE11D, K14R, A21T, V31I, I73V, T112V, T125A, G134N, I135V, K136R, D167E, V201I, L234I, D256E, S283GCRF01_AE
Rolland (2012)AA060a_WG8AA060a_WG8JX447367None  L68IK14R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, S153A, D167E, V201I, K211R, L234I, S283G, R284GCRF01_AE
Kijak (2013)04TH81719604TH817196JN248336None  L68IK14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K136Q, D167E, V201I, L234I, S283GCRF01_AE
Li (2013)21712171JQ302653None  L68IE11D, A21T, V31I, T112V, T124A, T125A, G134N, I135V, K136R, V165I, V176L, L234I, D256E, S283GCRF01_AE
 22342234JQ302699None  L68IK14R, A21T, A23V, V31I, S39N, L63V, I72V, T112V, T124A, T125A, G134N, I135V, K136R, K173R, V176L, V201I, L234I, S283GCRF01_AE
Reigadas (2013)347347JX425468None  L68IK14R, A21T, A23V, V31I, S39N, I72V, A98AE, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167DE, V201I, T206S, Q221T, L234I, S283GCRF01_AE