<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation T206S
Rx II-naive
IncludeMixtures No
References 15
Patients 49
Isolates 49
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Kijak (2004)0190MA01CM.0190AY371145None  L68IE11D, K14R, V31I, D41N, M50I, I72V, L101I, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, T206S, T218I, L234I, S283G, D288NCRF01_AE
Brown (2005)BB_96TH_NP104696TH_1046AY713421None   K14R, A21T, V31I, V32I, M50I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
Brennan (2008)71-171-1EU618287None   E11D, K14R, S24N, L28I, P30A, I72V, Q95X, Y99YF, L101I, T112V, T124A, T125A, G134N, I135V, D167E, V201I, T206S, L234I, S283GCRF01_AE
 ABB14-96ABB14-96EU618501None   E11D, A21T, D25E, V31I, I72V, T112V, T124A, T125A, G134N, I135V, V201I, T206S, K219N, N222K, L234I, S283GCRF01_AE
Sichtig (2009)23-E23-EFJ183546None   E11D, K14R, R20RG, M22MR, D25E, V31I, I60M, I72IV, T112V, T124A, T125A, V126M, I135V, K136Q, E157Q, K160Q, I162IV, S195ST, V201I, T206S, T218I, L234ICRF01_AE
Avi (2010)N69N69GQ926814None   R20K, V31I, I72V, L74I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, S255NCRF01_AE
Isarangkura-Na-Ayuthaya (2010)AE-Int-111AE-Int-111HM150832None   K14R, V31I, I72V, T112V, S119P, T124A, T125A, V126M, G134N, I135V, D167E, V201I, T206S, D207E, K211R, L234I, D256E, S283GCRF01_AE
 AE-Int-295AE-Int-295HM150865None   K14R, A21T, V31I, S39SN, I72V, T112V, T124A, T125A, G134N, I135V, K136KR, V165I, D167E, R187K, V201I, T206S, K211R, S230N, L234I, S283GCRF01_AE
Nouhin (2011)64KC64GU289842None   K14R, A21T, S39N, I72V, L101I, T112V, S123C, T124N, G134N, I135V, D167E, H171Q, I200M, V201I, T206S, L234I, S283GCRF01_AE
Wilantho A (2011)522995522995JF928849None   K14R, V31I, V32I, S57SG, I72IV, L101I, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, K215N, L234I, S283GCRF01_AE
 718019718019JF928902None   E11D, K14R, L28I, P30S, I72V, T112V, I113V, T124A, T125A, G134N, I135V, K136R, V201I, I203M, T206S, L234I, N254S, S255G, S283GCRF01_AE
 SL074SL074JF928947None   K14R, V32I, I72V, T112V, T124A, T125A, V126L, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 916776916776JF928908None   K14R, V31I, V32I, S57SG, I72IV, L101I, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, K215N, L234I, S283GCRF01_AE
 SL139SL139JF928965None   K14R, V31I, V32I, I72V, L101I, T112I, T124A, I135V, D167E, V201I, T206S, L234I, S283GCRF01_AE
 901320901320JF928907None   K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, T206S, L234ICRF01_AE
 SL111SL111JF928959None   K14R, A21T, A23V, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, E170L, V201I, T206S, L234I, S283GCRF01_AE
 SL130SL130JF928963None   K14R, A21AT, V31I, I72V, T112V, T124A, T125A, V126VIM, G134N, I135V, K136Q, D167E, V201I, T206S, I208L, L234I, S283GCRF01_AE
 524784524784JF928982None   K14R, V31I, I72V, T112I, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283G, R284GCRF01_AE
 819188819188JF928876None   K14R, V31I, V32I, S57SG, I72IV, L101I, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, K215N, L234I, S283GCRF01_AE
 523010523010JF928925None   K7KR, K14R, A21T, V31I, S39N, I72V, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
Chow (2012)10MYKJ06710MYKJ067JX390612None   K14R, A21T, A23V, S39N, L63V, I72V, L74I, E96D, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, T206S, K211KR, L234I, S283DCRF01_AE
Luu (2012)IVVI05455IVVI05455JQ288879None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, Q216H, L234I, S283GCRF01_AE
Monleau (2012)SK6007SK6007JQ250531None   D6DE, E11D, E13D, S24SN, V31I, I60M, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K186R, V201I, T206S, L234I, A265V, R269RK, S283GCRF01_AE
Rolland (2012)AA070a_LH07AA070a_LH07JX447491None   K14R, A21T, V31I, S39N, I72V, Q95H, K103R, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, R187K, V201I, T206S, L234I, S283GCRF01_AE
 AA073a_LH5AA073a_LH5JX447512None   S17N, V31I, I72V, K111Q, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 AA086a02LAA086a02LJX447690None   E11D, K14R, A21T, V31I, S39N, I72V, T112V, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 AA097a01LAA097a01LJX447848None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
Zeng (2012)CN0982CN0982JQ028219None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 CN1302CN1302JQ028255None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 CN1350CN1350JQ028266None   K14R, R20K, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, K219R, L234I, S283GCRF01_AE
 CN1389CN1389JQ028269None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 CN0713CN0713JQ028334None   K14R, A21T, A23V, V31I, V32I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, K215R, Q216N, L234I, S283GCRF01_AE
Li (2013)21682168JQ302650None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 20282028JQ302560None   K14R, A21AT, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193E, V201I, T206S, L234I, D279G, S283GCRF01_AE
 21232123JQ302623None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 21592159JQ302643None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 21552155JQ302641None   K7R, K14R, A21T, A23V, N27S, E35Q, S39N, I72V, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 21242124JQ302624None   K14R, A21T, A23V, V31I, S39N, I72V, L101I, K103R, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, R187K, V201I, T206S, L234I, S283GCRF01_AE
 22082208JQ302678None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 20762076JQ302596None   K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
Reigadas (2013)303303JX425424None   K14R, A21T, A23V, D25DE, V31I, S39N, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136QR, V165I, K173R, V201I, T206S, L234I, S283GCRF01_AE
 335335JX425456None   K14R, A23V, S24N, V31I, D41S, M50I, I72V, L101I, T112V, I113V, T124A, T125A, G134D, K136Q, D167E, E170K, V201I, T206S, L234I, S283G, D288NCRF01_AE
 347347JX425468None  L68IK14R, A21T, A23V, V31I, S39N, I72V, A98AE, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167DE, V201I, T206S, Q221T, L234I, S283GCRF01_AE
 601601JX425846None   V31I, I72V, T112V, T124A, T125A, G134N, I135V, E157Q, K160Q, F181L, V201I, T206S, L234I, A265V, R269K, S283GCRF01_AE
 607607JX425852None   K14R, V31I, L45Q, I72V, L74I, E96D, T112V, T124A, T125A, V126M, G134N, I135V, K136Q, V201I, T206S, E212HQ, L234I, D256E, S283G, D286ECRF01_AE
 613613JX425857None   K14R, A21T, V31I, L63LV, I72IV, I84M, T112V, I113V, T124A, T125A, K136Q, V201I, T206S, Q221K, L234I, S255N, S283GCRF01_AE
 759759JX425885None   K14R, D25E, V31I, I72V, G94GR, T112V, T124A, T125A, G134N, I135V, I141IV, G189GW, A196AT, V201I, T206S, Q216N, L234I, S255SN, I268IL, D270HN, S283GCRF01_AE
 4136241362JX451910None   E11D, K14R, S24N, V32I, E35EK, V37VM, K42R, E87E*, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, V201I, T206S, I208M, T210TS, L234I, S283SGCRF01_AE
 4163841638JX451916None   E11D, K14R, A21T, V31I, D41N, M50I, I72V, I84L, L101I, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, T206S, I208L, E212I, Q216H, K219N, L234I, S283G, D288NCRF01_AE