<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation T206S
Rx II-naive
IncludeMixtures No
References 11
Patients 16
Isolates 16
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Kijak (2004)0190MA01CM.0190AY371145None  L68IE11D, K14R, V31I, D41N, M50I, I72V, L101I, T112V, T124A, T125A, G134D, K136Q, D167E, V201I, T206S, T218I, L234I, S283G, D288NCRF01_AE
Brown (2005)BB_96TH_NP104696TH_1046AY713421None   K14R, A21T, V31I, V32I, M50I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
Brennan (2008)71-171-1EU618287None   E11D, K14R, S24N, L28I, P30A, I72V, Q95X, Y99YF, L101I, T112V, T124A, T125A, G134N, I135V, D167E, V201I, T206S, L234I, S283GCRF01_AE
 ABB14-96ABB14-96EU618501None   E11D, A21T, D25E, V31I, I72V, T112V, T124A, T125A, G134N, I135V, V201I, T206S, K219N, N222K, L234I, S283GCRF01_AE
Sichtig (2009)23-E23-EFJ183546None   E11D, K14R, R20RG, M22MR, D25E, V31I, I60M, I72IV, T112V, T124A, T125A, V126M, I135V, K136Q, E157Q, K160Q, I162IV, S195ST, V201I, T206S, T218I, L234ICRF01_AE
Avi (2010)N69N69GQ926814None   R20K, V31I, I72V, L74I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, S255NCRF01_AE
Isarangkura-Na-Ayuthaya (2010)AE-Int-111AE-Int-111HM150832None   K14R, V31I, I72V, T112V, S119P, T124A, T125A, V126M, G134N, I135V, D167E, V201I, T206S, D207E, K211R, L234I, D256E, S283GCRF01_AE
 AE-Int-295AE-Int-295HM150865None   K14R, A21T, V31I, S39SN, I72V, T112V, T124A, T125A, G134N, I135V, K136KR, V165I, D167E, R187K, V201I, T206S, K211R, S230N, L234I, S283GCRF01_AE
Nouhin (2011)64KC64GU289842None   K14R, A21T, S39N, I72V, L101I, T112V, S123C, T124N, G134N, I135V, D167E, H171Q, I200M, V201I, T206S, L234I, S283GCRF01_AE
Chow (2012)10MYKJ06710MYKJ067JX390612None   K14R, A21T, A23V, S39N, L63V, I72V, L74I, E96D, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, T206S, K211KR, L234I, S283DCRF01_AE
Luu (2012)IVVI05455IVVI05455JQ288879None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, Q216H, L234I, S283GCRF01_AE
Monleau (2012)SK6007SK6007JQ250531None   D6DE, E11D, E13D, S24SN, V31I, I60M, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K186R, V201I, T206S, L234I, A265V, R269RK, S283GCRF01_AE
Rolland (2012)AA070a_LH07AA070a_LH07JX447491None   K14R, A21T, V31I, S39N, I72V, Q95H, K103R, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, R187K, V201I, T206S, L234I, S283GCRF01_AE
 AA073a_LH5AA073a_LH5JX447512None   S17N, V31I, I72V, K111Q, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 AA086a02LAA086a02LJX447690None   E11D, K14R, A21T, V31I, S39N, I72V, T112V, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE
 AA097a01LAA097a01LJX447848None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T206S, L234I, S283GCRF01_AE