<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation I203M
Rx II-naive
IncludeMixtures No
References 18
Patients 48
Isolates 48
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Tovanabutra (2003)99TH_R239999TH_R2399AF530576None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, I203M, L234I, S283GCRF01_AE
Tovanabutra (2004)01THOUR414I01_414IAY358050None   K14R, A21T, V31I, S39N, D41N, I72V, T112V, T124A, T125A, V126M, G134D, I135V, K136H, D167E, V201I, I203M, L234I, S283G, D288NCRF01_AE
 01THOUR788I01_788IAY358068None   K14R, A21T, S24G, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, I203M, L234I, S283GCRF01_AE
 02THOUR847I02_847IAY358069None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, I203M, K215R, L234I, S283GCRF01_AE
Tee (2006)KL03105_031.1DQ366661None   K14R, A21T, V31I, S39N, L63V, I72V, T112V, T124A, T125A, G134N, I135V, K136R, Q137R, D167E, V201I, I203M, L234I, S283GCRF01_AE
Hai-Long (2007)Fj065Fj065EF036534None   K14R, A21T, A23V, V31I, V32I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, R224Q, L234I, S283GCRF01_AE
Isarangkura-Na-Ayuthaya (2010)AE-Int-14AE-Int-14HM150810None   E11D, A21T, V31I, S39N, I72V, T112V, T125A, G134N, I135V, K136R, D167E, V201I, I203M, T218S, L234I, D253E, S283GCRF01_AE
 AE-Int-23AE-Int-23HM150813None   K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, I200M, V201I, I203M, L234I, S283GCRF01_AE
 AE-Int-95AE-Int-95HM150827None   E11D, K14R, A21T, V31I, M50I, L63V, I72V, I84L, T112V, T124A, T125A, G134N, I135V, K136R, V165I, I200M, V201I, I203M, L234I, S283GCRF01_AE
 AE-Int-271AE-Int-271HM150853None   E11D, K14R, A21T, V31VI, L63V, I72V, I84L, T112V, I113V, T125A, G134N, K136Q, V201I, I203M, L234ICRF01_AE
 AE-Int-300AE-Int-300HM150867None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126L, I135V, D167E, K188R, V201I, I203M, L234I, S283GCRF01_AE
 AE-Int-308AE-Int-308HM150868None   K14R, V31I, S39N, I72V, L101I, T112V, T124N, T125A, G134N, I135V, K136R, V165I, D167E, G193E, V201I, I203M, L234I, S283G, D286NCRF01_AE
 AE-Int-381AE-Int-381HM150879None   K14R, A21T, S39N, L45V, I72V, T112V, I113V, T124A, T125A, G134S, K136H, V165I, V201I, I203M, L234I, D256E, S283GCRF01_AE
 AE-Int-385AE-Int-385HM150881None   V31I, S39N, I72V, T112V, T124N, T125A, G134N, I135V, K136Q, V165I, D167E, V201I, I203M, L234I, S283GCRF01_AE
Sanders-Buell (2010)569M569MGQ477441None  L74MK14R, R20K, S39N, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, T218I, K219N, L234I, D256E, S283GCRF01_AE
Brenner (2011)62406240HQ207731None   K14R, A21T, V31I, S39N, I72V, T112V, T125A, V126L, K127KR, G134N, I135V, K136R, D167DE, V201I, I203M, L234I, S283GCRF01_AE
 73167316HQ207755None   K14R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
Wilantho A (2011)SL102SL102JF928955None   K14R, A21T, V31I, S39N, I72IV, T112V, I113IV, T124H, T125A, G134N, K136Q, D167E, V201I, I203M, L234I, S283GCRF01_AE
 SL065SL065JF928940None   E11D, K14R, A21T, V31I, M50L, I72IV, I84L, T112V, I113V, N117NS, T125A, G134N, E157Q, K160Q, D167E, V201I, I203M, L234I, D256E, S283GCRF01_AE
 610640610640JF928862None   K14R, A21T, A23V, V31I, S39N, L101V, T112V, T124A, T125A, I135V, K136R, D167DE, H171HQ, V201VI, I203M, K215KN, I220IL, R224RW, L234ICRF01_AE
 718019718019JF928902None   E11D, K14R, L28I, P30S, I72V, T112V, I113V, T124A, T125A, G134N, I135V, K136R, V201I, I203M, T206S, L234I, N254S, S255G, S283GCRF01_AE
 811691811691JF928990None   E11D, K14R, A21T, V31I, V32I, L101I, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
 SL100SL100JF928953None   E11D, K14R, A21T, V31I, L45V, I72V, I84IL, T112V, T124A, T125A, G134N, I135V, K136QR, D167E, V201I, I203M, L234I, S283GCRF01_AE
 520500520500JF928846None   K14R, A21AT, V31I, I72V, K111R, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, I203M, L234I, S283GCRF01_AE
 600333600333JF928855None   E11D, K14R, R20RK, A21T, V31VIM, L45Q, T112V, T124A, T125A, G134N, I135V, K136Q, V165I, V201I, I203M, K211KR, L234I, S283GCRF01_AE
An (2012)09LNA00809LNA008JX960604None   K14R, V31I, I72V, T112V, I113V, T124A, T125A, G134N, I135V, K136R, H171Q, G193E, V201I, I203M, L234I, S283G, D288NCRF01_AE
 09LNA01109LNA011JX960605None   K14R, V31I, I72V, T112V, I113V, T124A, T125A, G134N, I135V, K136R, H171Q, G193E, V201I, I203M, L234I, S283G, D288NCRF01_AE
 08LNA00308LNA003JX960606None   V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193E, V201I, I203M, L234I, S283G, D288NCRF01_AE
Chow (2012)11FIR16411FIR164JX390610None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, I203M, L234I, S283GCRF01_AE
Rolland (2012)AA006a03AA006a03JX446737None   E11D, K14R, A21T, V31I, V32I, S39N, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
 AA008a_LH15AA008a_LH15JX446769None   K14R, A21T, A23V, V31I, S39N, L45V, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, K188R, V201I, I203M, L234I, S283GCRF01_AE
 AA009b03LAA009b03LJX446787None   K14R, A21T, V32I, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, V165I, V201I, I203M, L234I, S283GCRF01_AE
 AA044a_LH20AA044a_LH20JX447218None   E11D, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283DCRF01_AE
 AA108a_WG2AA108a_WG2JX448029None   E11D, K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, I203M, L234I, S283GCRF01_AE
 AA112a05LAA112a05LJX448068None   D6N, K14R, A21T, V31I, L45Q, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, K215R, L234I, S283GCRF01_AE
 AA129a07LAA129a07LJX448284None   K14R, A21T, V31I, S39N, T112V, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
Zeng (2012)CN1255CN1255JQ028355None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
 CN1304CN1304JQ028363None   K14R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
Kijak (2013)04TH42799004TH427990JN248327None   E11D, V32I, I72V, T112V, T125A, V126M, G134N, I135V, K136R, D167E, S195T, V201I, I203M, L234I, S283GCRF01_AE
Kotaki (2013)SM2SM2KF735917None   E11D, A21T, V31I, M50I, Q95N, L101I, T112V, T124A, T125A, G134N, I135V, K136N, D167E, V201I, I203M, L234ICRF01_AE
Li (2013)28042804JQ901025None   K14R, A21T, V31I, V32I, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
 28902890JQ901092None   K14R, V31I, V32VI, I72V, L101I, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, I203M, D232E, L234I, S283GCRF01_AE
Li (2013)21812181JQ302660None   K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, S283GCRF01_AE
 20322032JQ302564None   K14R, A21T, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, V165I, D167E, V201I, I203M, L234I, S283GCRF01_AE
 20782078JQ302598None   A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234I, V249A, S283GCRF01_AE
 21832183JQ302662None   K14R, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, G193E, V201I, I203M, T210N, L234I, S283G, D288NCRF01_AE
Li (2013)hntk1hntk1KC988059None   K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, I203M, L234V, S283GCRF01_AE
Nerrienet (2014)U0302042U0302042JN675736None   V31I, L63V, I72V, T112V, T124A, T125A, G134N, I135V, D167E, V201I, I203M, I208L, L234I, S283GCRF01_AE