<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation G163E
Rx II-naive
IncludeMixtures No
References 13
Patients 27
Isolates 27
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Tovanabutra (2005)00US_MSC116400US_1164AY444804None   K14R, A21T, V31I, S39N, T112V, T124A, T125A, G134N, I135V, G163E, D167E, V201I, L234I, S255N, S283GCRF01_AE
Nouhin (2011)52KC52GU289830None   E11D, K14R, A21T, V31I, S39N, S57N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, S153SF, G163E, D167E, V201I, D202DV, L234I, S283GCRF01_AE
Rolland (2012)AA013a05AA013a05JX446848None   K14R, M50L, T112V, T124A, T125A, V126L, I135V, K136R, G163E, D167E, V201I, L234I, D253DG, S283GCRF01_AE
 AA014a02LAA014a02LJX446859None   K14R, A21T, V31I, I72V, T112V, T124A, T125A, V126L, G134N, I135V, K136R, G163E, V201I, L234ICRF01_AE
 AA024a08AA024a08JX446989None   K14R, S17N, L28I, S39N, L45V, L101I, T112V, T124A, T125A, G134N, I135V, K136R, G163E, D167E, V201I, K211R, L234I, S283GCRF01_AE
 AA042a07LAA042a07LJX447193None   E11D, A21T, V31I, S39N, I72V, L74I, T112V, T125A, V126L, G134N, I135V, K136Q, G163E, V201I, L234I, S255NCRF01_AE
 AA069a02LAA069a02LJX447478None   K14R, R20K, V31I, L101I, T112V, T124N, G134N, I135V, K136R, G163E, V201I, T218S, I220L, L234I, S283GCRF01_AE
Kijak (2013)05TH24565105TH245651JN248340None   K14R, A21T, A38K, S39N, I72V, L101I, T112V, T124N, T125A, G134N, I135V, K160R, G163E, D167E, E198D, V201I, L234I, S283GCRF01_AE
Li (2013)21312131JQ302628None   K14R, V31I, S39N, I72V, T112V, T125A, V126L, G134N, I135V, K136Q, G163E, V201I, L234I, S283G, D286NCRF01_AE
Nerrienet (2014)Q0920081Q0920081JN675720None   K14R, H16HP, D25DE, V31I, I72V, P90PS, T112V, T124A, T125A, V126M, G134N, I135V, K136R, G163E, V201I, T218S, L234I, S283GCRF01_AE
Cheong (2015)10MYPR26810MYPR268KR019771None   S17N, L63V, I72V, L74I, T112I, I113V, T124A, T125A, G134N, G163E, D167E, V201I, L234I, S283GCRF01_AE
Hachiya (2015)N0813N0813LC022523None   K14R, A21T, V31I, I72V, L101V, T112V, T125V, G134N, I135V, K136R, K160R, G163E, K188R, V201I, L234I, S283GCRF01_AE
Hora (2015)DE00110CN009DE00110CN009KP109507None   E11D, K14R, A21T, T112V, T124A, T125A, G134N, I135V, K136R, G163E, D167E, V201I, L234I, S255N, S283GCRF01_AE
Li (2016)ZHP-86ZHP-86KT192025None   E11D, K14R, A21T, A23V, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, G163E, D167E, V201I, L234I, S283GCRF01_AE
 ZHP-87ZHP-87KT192026None   E11D, K14R, A21T, A23V, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, G163E, D167E, V201I, L234I, S283GCRF01_AE
Van Tran (2016)VI-223VI-223LC101079None   K14R, A21T, S39N, I72V, L101I, K111R, T112V, T124A, T125A, G134N, I135V, K136Q, G163E, D167E, R187K, V201I, L234I, D279G, S283GCRF01_AE
 VI-117VI-117LC100984None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126M, K127R, G134N, I135V, K136H, G163E, D167E, V201I, L234I, D279GCRF01_AE
 VI-300VI-300LC101146None   E11D, K14R, A21T, V31I, T112V, T124A, T125A, G134N, I135V, K136R, G163E, V201I, L234I, S283GCRF01_AE
 VI-256VI-256LC101109None   K14R, A21T, V31I, S39N, I72V, T112V, T124N, T125A, G134N, I135V, K136R, G163E, D167E, V201I, L234I, S283GCRF01_AE
Chehadeh (2017)61346134KY888235None   K14R, A21T, D25N, S39N, K103R, T112V, T124A, T125A, G134N, I135V, K136R, G163E, V201I, I203M, L234I, S283GCRF01_AE
Hachiya (2017)B15-5110116LC160428LC160428None   K14R, V31I, I72V, T112V, I113IV, T124A, T125A, G134N, I135V, K136R, G163E, V201I, L234I, S283GCRF01_AE
 C15-50594694392LC160477LC160477None  L74MV31I, S39N, I72V, Q95QP, T112V, T124N, T125A, V126L, G134N, I135V, K136R, G163E, V201I, I203M, L234I, S283GCRF01_AE
 C15-55550012LC161187LC161187None   E11D, S17T, V31I, L101I, T112V, T124N, T125A, G134N, I135V, K136Q, G163E, D167E, V201I, T218S, L234I, V259I, S283SNCRF01_AE
 E14-50911603LC161374LC161374None   K14R, A21T, V31I, T112V, I113V, T124A, T125A, V126M, G134N, G163E, V201I, L234I, S283GCRF01_AE
 E14-50911597LC161375LC161375None   K14R, A21T, V31I, K42KR, T112V, I113V, T124A, T125A, V126M, G134N, G163E, V201I, L234I, S283GCRF01_AE
 E14-50911594LC161379LC161379None   K14R, A21T, V31I, T112V, I113V, T124A, T125A, V126M, G134N, G163E, V201I, K211KT, L234I, S283GCRF01_AE
 E14-50911626LC161382LC161382None   K14R, A21T, V31I, I72V, L101V, T112V, T125V, G134N, I135V, K136R, K160R, G163E, V165VI, K188R, V201I, L234I, S283GCRF01_AE