<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype CRF01_AE
Gene IN
Mutation E157Q
Rx II-naive
IncludeMixtures No
References 7
Patients 12
Isolates 13
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Brennan (2008)ABB165-98ABB165-98EU618607None   K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, K136Q, E157Q, D167E, V201I, L234I, S283GCRF01_AE
Eshleman (2009) ABB165-98FJ480312None   K14R, A21T, V31I, I72V, K111KR, T112V, T124A, T125A, G134N, K136Q, E157Q, D167E, V201I, L234I, S283GCRF01_AE
Nouhin (2011)128059KCT0128059GU289833None   K14R, A21T, V31I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160T, D167E, V201I, K215N, L234I, S283GCRF01_AE
Wilantho A (2011)511282511282JF928839None   K14R, A21T, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160T, D167E, V201I, L234I, S283G, R284GCRF01_AE
 SL065SL065JF928940None   E11D, K14R, A21T, V31I, M50L, I72IV, I84L, T112V, I113V, N117NS, T125A, G134N, E157Q, K160Q, D167E, V201I, I203M, L234I, D256E, S283GCRF01_AE
Zeng (2012)CN1287CN1287JQ028246None   K14R, A21T, V31I, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160T, D167E, V201I, L234I, S283GCRF01_AE
 CN1206CN1206JQ028343None   K14R, A21T, V31I, S39N, K46Q, M50I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, D167E, V201I, L234I, S283GCRF01_AE
 CN1370CN1370JQ028369None   K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160A, D167E, V201I, L234I, S283GCRF01_AE
Reigadas (2013)601601JX425846None   V31I, I72V, T112V, T124A, T125A, G134N, I135V, E157Q, K160Q, F181L, V201I, T206S, L234I, A265V, R269K, S283GCRF01_AE
Van Tran (2016)VI-405VI-405LC101250None   K14R, V31I, I72V, T112V, T124A, T125A, G134GD, I135V, K136QR, E157Q, K160Q, D167E, V176L, V201I, K211R, L234I, S283GCRF01_AE
 VI-292VI-292LC101139None   K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, E157Q, K160T, D167E, V201I, I203M, I208L, L234I, S283GCRF01_AE
 VI-357VI-357LC101210None   K14R, A21T, D25E, V31I, S39N, I72V, T112V, T124A, T125A, V126VM, G134N, I135V, K136R, E157Q, K160GR, D167E, V201I, L234I, S283GCRF01_AE
 VI-138VI-138LC101007None   K14R, V31I, I72V, T112V, T124A, T125A, G134N, I135V, E157Q, K160Q, D167E, G193D, S195C, V201I, L234I, V260I, S283GCRF01_AE