<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation T97A
Rx II-naive
IncludeMixtures No
References 8
Patients 10
Isolates 10
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Novitsky (2002)00BW147100BW1471AF443091None  T97AK14R, S24N, D25E, V31I, I72V, L101I, K111Q, T112I, T124A, T125A, K136Q, E152K, Q177L, T206S, D232E, L234V, D278A, S283GC
Yang (2003)HH069HH069AP005206None  T97AV31I, K42Q, I84M, L101V, T112V, T124A, T125A, K136Q, V201I, L234I, R269K, D278A, S283G, D286NC
Rousseau (2006)Pt17804SK133B1AY772698None  T97AK14R, V31I, L101I, T112V, T124A, T125A, K136Q, V180A, V201I, T218I, L234I, R269K, D278A, S283GC
Matthews (2008)SK133SK133FJ199910None  T97AK14R, V31I, L101I, T112V, T124A, T125A, K136Q, V180A, V201I, T218I, L234I, R269K, D278A, S283GC
Passaes (2009)BR.RS.RGS81BR.RS.RGS81HM026813None  T97AK14R, V31I, M50T, L101I, T112I, T124N, K136Q, V201I, T206S, T218I, L234I, I251L, A265V, R269K, D278A, R284GC
Fish (2010)FV2505ZAFV25GQ872532None  T97AE11D, V31I, M50I, L74I, L101V, T112V, T124A, T125A, V126F, G134D, K136Q, D167E, V201I, L234I, D278A, S283GC
Novitsky (2015)mpp_189mpp_189KR860970None  T97AK14R, D25E, V31I, M50T, I84M, A91E, F100Y, L101I, T112V, S119R, T124A, T125A, K136Q, F181L, V201I, L234IC
 mpp_425mpp_425KR861188None  T97AD6E, D25E, V31I, M50I, I72V, I84M, L101I, G106A, T112I, K136Q, V201I, T218I, L234I, A265V, R269KC
 mpp_062mpp_062KR860848None  T97AE11D, E13D, K14R, S24N, D25E, V31I, M50I, I84M, L101I, T112I, T124A, T125A, K136Q, V201I, T206S, L234I, A265V, R269KC
Billings (2016)CO3817V2CO3817V2KX907387None  T97AK14R, V31I, L101I, K111R, T112V, T124A, T125A, K136Q, V201I, K211Q, Q216R, T218I, K219Q, L234I, R269K, D278AC