<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation I72T
Rx II-naive
IncludeMixtures No
References 11
Patients 17
Isolates 17
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Novitsky (2002)00BW388600BW3886AF443112None   D25E, V31I, M50I, I72T, F100Y, L101I, T112V, T124A, T125A, K136Q, E152G, V201I, K215N, T218I, L234I, N254K, S255G, R269K, D278A, S283GC
 00BW076200BW0762AF443088None   E10D, S24N, D25E, V31I, M50I, I72T, I84M, F100Y, L101I, T112I, T124A, T125A, K136Q, K188R, V201I, K211R, Q216R, T218I, K219Q, L234I, V260I, R269K, D278A, S283GC
Rousseau (2006)Pt1303PS024MB1DQ396367None   D25E, V31I, M50I, I72T, F100Y, L101I, T112V, T125V, K136Q, E152K, K159R, V201I, L234I, A265V, R269K, D278A, S283GC
Visawapoka (2006)KNH1268KNH1268AY945738None   E13D, S17N, M50T, I72T, I84M, F100Y, L101I, T112V, T124S, T125A, K136Q, K188R, V201I, K211R, T218I, L234I, A265V, R269K, D278A, S283GC
Matthews (2008)J3MJ3MFJ199580None   S17N, V31I, M50I, I72T, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, V201IC
 PS024PS024FJ199605None   D25E, V31I, M50I, I72T, F100Y, L101I, T112V, T125V, K136Q, E152K, K159R, V201I, L234I, A265V, R269K, D278A, S283GC
Fish (2010)P5009ZAP50GQ872504None   D3E, E11D, S17N, D25E, M50T, H51Q, I72T, I84M, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, L234I, D278A, S283GC
 FV2305ZAFV23GQ872531None   S24N, D25E, I72T, F100Y, L101I, T112V, T125A, K136Q, V201I, T218I, L234I, D278AC
Bessong (2013)08MB62ZA08MB62ZAHM569330None   D25E, V31I, I72T, T112V, T125V, K136Q, D167E, V201I, L234I, S283GC
Li (2015)11381138KP234928None   D6N, K14R, V31I, K42Q, I72T, I84M, L101I, T112V, T124A, T125A, I135V, K136Q, V201I, L234S, R269K, D278A, S283GC
Novitsky (2015)mpp_463mpp_463KR861222None   S17N, V31I, S39N, M50I, H51Q, I72T, E96D, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, T218L, L234I, A265V, R269KC
 bcpp_333bcpp_333KR860734None   K7Q, K14R, V31I, L45Q, I72T, F100Y, L101I, T112I, T124A, T125A, K136Q, G163V, V201I, K211R, T218I, L234I, R269KC
Billings (2016)CO3979V3CO3979V3KX907392None   S17N, D25E, V31I, M50I, I72T, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, T218I, L234I, A265V, R269K, D278A, S283GC
Sachithanandham (2016)11N/167511N/1675KF870736None   V31I, K42Q, I60M, I72T, L74I, I84L, L101I, T112V, S119T, T124A, K136Q, E198D, V201I, I217V, T218L, L234I, D278AC
 DR11/57DR11/57KF870832None   V31I, K42Q, I60M, I72T, L74I, I84L, L101I, T112V, S119T, T124A, K136Q, E198D, V201I, I217V, L234I, D278AC
Inzaule (2018)SATLCPM003SATLCPM003MG693971None   P30S, M50I, I72T, F100Y, L101I, T112V, S119T, T124A, T125A, K136Q, V201I, K211N, T218I, L234I, D278A, S283GC
 SAACCPM098SAACCPM098MG693920None   K14R, D25E, V31I, M50I, I72T, F100Y, L101I, K111R, T112V, S119P, T122I, T124A, T125A, K136Q, V201I, T206S, T218I, L234I, S255G, R269K, D278A, S283GC