<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation S230N
Rx II-naive
IncludeMixtures No
References 6
Patients 28
Isolates 28
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
van Harmelen (2001)JH_Du179JH_Du179AY043174None   D25E, V31I, L45Q, I72V, I84M, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, T218I, S230N, L234I, A265V, D278A, S283GC
Novitsky (2002)00BW179500BW1795AF443097None   S24N, D25E, V31I, M50I, I73V, I84L, A91T, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, I251L, D256E, A265V, D278A, S283GC
 98BWMC1398BWMC13AF443077None   E10D, E11D, K14R, S24N, D25E, V31I, M50I, F100Y, L101I, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, D256E, A265V, D278A, S283GC
 96BWMO196BWMO1AF443074None   K14R, D25E, V31I, M50I, I84M, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, D256E, D278A, S283GC
Passaes (2009)BR.RS.HC07BR.RS.HC07HM026792None   E11D, K14R, D25E, V31I, M50T, E96D, L101I, T112V, T124N, K136Q, V201I, K219N, N222K, S230N, L234I, I251L, R269K, D278A, V281MC
Li (2013)28072807JQ901026None   V31I, K42Q, L101I, T112V, T124A, T125A, I135L, K136Q, V201I, S230N, L234S, R269K, D278A, S283GC
Li (2015)951951KP235138None   V31I, K42Q, I84M, L101I, T112V, T124A, T125A, K136Q, V201I, S230N, L234S, R269K, D278A, S283GC
 13641364KP235064None   L28I, K42Q, L45Q, L101I, T112V, K136Q, Q164L, K211R, S230N, L234I, R269K, D278A, S283G, D288NC
 13751375KP235074None   K14R, D41N, K42Q, I84M, L101I, T112V, T125A, K136Q, V201I, T206S, S230N, L234N, R269K, D278A, S283GC
 930930KP235121None  L68VK14R, D41N, K42Q, Q62R, I84M, L101I, T112V, T124N, T125A, K136Q, V201I, K211R, S230N, L234S, R269K, D278A, S283GC
 926926KP235119None   K14R, D41N, K42Q, I84M, L101I, T112V, T125A, K136Q, V201I, D202V, T206S, S230N, L234N, R269K, D278A, S283GC
 11831183KP234960None   V31I, K42Q, I84M, L101I, T112V, T125A, K136Q, V201I, S230N, L234S, R269K, D278A, S283GC
Novitsky (2015)mpp_399mpp_399KR861163None   K14R, D25E, V31I, S39N, L45V, M50I, I84M, L101I, T112I, K136Q, G163T, V201I, K211R, K215N, T218I, S230N, L234I, D256EC
 mpp_323mpp_323KR861096None   E10D, D25E, V31I, M50I, I72V, I84M, F100Y, L101I, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, I251L, D256E, A265VC
 mpp_171mpp_171KR860953None   K14R, D25E, V31I, L45I, A49S, M50I, I72V, F100Y, L101I, T112V, S119G, T122I, T124A, T125A, K136Q, K188R, V201I, K211R, S230N, L234I, I251L, D256E, A265VC
 mpp_330mpp_330KR861102None   S17N, V31I, L45Q, M50I, I72V, E96D, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, T218I, S230N, L234I, D256EC
 mpp_321mpp_321KR861094None   S17N, D25E, M50I, I72V, I84M, E96D, F100Y, L101I, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, I251L, D256E, A265VC
 mpp_038mpp_038KR860826None   S17N, D25E, V31I, M50I, I72V, T112I, T124A, T125A, K136Q, V201I, T210I, K211R, T218I, S230N, L234I, I251L, D256E, A265VC
 mpp_044mpp_044KR860831None   E11D, A21T, D25E, V31I, M50I, I84M, A91T, F100Y, L101I, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, D256E, A265VC
 mpp_176mpp_176KR860958None   K14R, D25E, V31I, I84M, F100Y, L101I, T124A, T125A, G163E, I200M, V201I, K211R, T218I, Q221H, S230N, L234I, D256EC
 mpp_489mpp_489KR861246None   S17N, V31I, M50I, I72V, L101I, T112I, T124A, K136Q, V201I, K211R, T218I, S230N, L234I, I251L, D256E, A265V, R269KC
 bcpp_200bcpp_200KR860685None   K14R, D25E, N27D, V31I, M50I, Y99F, F100Y, L101I, G106A, T112I, T124A, T125A, K136Q, V201I, T206S, S230N, L234I, D256EC
 mpp_209mpp_209KR860989None   S17N, D25E, V31I, M50I, F100Y, L101I, T112I, S119T, T124A, T125A, K136Q, V201I, T218I, S230N, L234I, D256EC
 mpp_163mpp_163KR860946None   K14R, S17N, D25E, V31I, M50I, I72V, I84M, F100Y, L101I, T112I, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, D256E, A265V, R269KC
 bcpp_192bcpp_192KR860682None   K14R, R20RK, D25E, V31I, M50I, I84M, L101I, T112AV, T124A, V150VA, S153C, V201I, K211R, T218I, S230N, R231K, L234IC
 bcpp_060bcpp_060KR860627None   D25E, V31I, I84L, F100Y, L101I, T112V, T125A, K136Q, V201I, K215N, S230N, L234I, I251L, A265VC
 mpp_285mpp_285KR861061None   K14R, D25E, V31I, M50I, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, Q216R, T218I, K219Q, Q221H, S230N, L234I, D256E, A265VC
 mpp_150mpp_150KR860933None   K14R, D25E, V31I, M50I, I72V, I84M, L101I, K111R, T112I, T125V, K136Q, H171Q, V201I, K211R, T218I, S230N, L234I, A265V, R269KC