<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase Inhibitors

Subtype C
Gene IN
Mutation I203M
Rx II-naive
IncludeMixtures No
References 13
Patients 20
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# INIs WksINIMajorDRMs INIMinorDRMs OtherMutSubtype
Novitsky (1999)96BW1196BW11 None   D25E, V31I, M50I, I72V, F100Y, L101I, T112I, T124A, T125A, K136Q, V201I, I203M, T218I, L234I, A265V, D278A, S283GC
Harris (2003)99ET399ET3AY255827None   D25E, V31I, L45V, I84M, F100Y, L101I, T112V, T124N, V201I, I203M, L234I, A265V, R269K, D278AC
Papathanasopoulos (2003)99ZATM1099ZATM10AY228556None   S24N, D25E, M50I, I84M, F100Y, L101I, T112V, T125A, K136Q, V201I, I203M, K215N, L234I, V260I, D278A, S283GC
Rousseau (2006)Pt3903PS073MB1DQ275649None   D6E, S17N, D25E, V31I, S39N, M50T, F100Y, L101I, T112V, T125A, K136Q, G163E, V201I, I203M, T218I, L234I, A265V, D278A, S283GC
 Pt21204SK184B1DQ056418None  T66SV31I, M50T, I72V, P90S, F100Y, L101I, T112V, S119P, T124N, T125A, K136Q, V201I, I203M, T218I, I220V, L234I, R269K, D278A, S283GC
Andresen (2007)CTL 015CTL 015EF514713None  G163RE11D, D25E, K34R, M50I, F100Y, L101I, T112V, T125A, K127R, K136Q, V201I, I203M, L234I, M275V, D278A, S283GC
Badreddine (2007)J11460SB_J11460DQ375275None   S24N, D25E, S39C, M50I, F100Y, L101I, T124Q, T125A, K188R, V201I, I203M, K215N, T218I, L234I, I251L, R269K, D278AC
Matthews (2008)12141214FJ199555None   E11D, Y15H, S24N, D25E, V31I, L45I, I72V, V88X, F100Y, L101I, T112V, T125A, K136Q, V201I, I203M, T218I, L234I, N254S, A265V, R269K, D278AC
 PS073PS073FJ199653None   D6E, S17N, D25E, V31I, S39N, M50T, F100Y, L101I, T112V, T125A, K136Q, G163E, V201I, I203M, T218I, L234I, A265V, D278A, S283GC
 SK184SK184FJ199953None  T66SV31I, M50T, I72V, P90S, F100Y, L101I, T112V, S119P, T124N, T125A, K136Q, V201I, I203M, T218I, I220V, L234I, R269K, D278A, S283GC
Garrido (2009)237INT-237GU217084None   V31I, L45I, G47R, E48G, M50I, I72V, F100Y, L101I, K111R, T112V, T124A, T125A, K136Q, D167E, K188R, V201I, I203M, T218I, L234I, A265V, R269KC
 363INT-363GU217210None   E11D, S24N, D25E, V31I, L45Q, M50I, F100Y, L101I, T112V, S119P, T125A, K136Q, V201I, I203M, T206S, T218I, L234I, W243R, D278A, S283GC
Passaes (2009)02F3102.BR.HF31GQ365649None   V32I, M50T, L101I, T112V, T124N, K136Q, K156R, I203M, L234I, V281MC
Graf (2011)SC96SC96JF773871None   D25E, V31I, V32I, L45V, L101V, T112V, S119P, T124N, K136Q, V165I, V201I, I203M, T218I, L234I, I251L, A265V, R269K, D278A, D288NC
 SC99SC99JF773873None   D25E, V32I, M50T, L101I, T112A, T124N, K136Q, I203M, T218I, L234I, R269K, D278A, V281MC
Wilantho A (2011)421377421377JF928827None   S24N, D25E, V31I, S39C, I60M, I72V, I84M, F100Y, L101I, T112V, T125A, D167E, K173KR, K188R, V201I, I203M, T206S, K215N, T218L, L234I, I268IL, R269K, D278A, S283GC
 421376421376JF928826None   K14X, S24N, D25E, V31I, V32I, S39C, I60M, I72V, I84M, F100Y, L101I, T112V, T125A, D167E, K173R, K188R, V201I, I203M, T206S, K215N, T218L, L234I, I268L, R269K, D278A, S283GC
Oliveira (2012)GA10GA10JQ670797None   D6E, E10D, D25E, V31I, L45M, I84M, A91T, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, I203M, L234I, R269K, D278A, S283GC
 GC42GC42JQ670834None   S17N, D25E, V31I, F100Y, L101I, G106A, T112V, T124A, T125A, K136Q, D167E, V201I, I203M, T218I, L234I, S283GC
Bessong (2013)08BBVCT3808BBVCT38HM569284None   D25E, V31I, M50I, I72V, L74I, F100Y, L101I, T112V, T124A, T125A, K136Q, D167E, V201I, I203M, K211R, T218I, L234I, N254H, A265V, R269K, D278A, V281M, S283GC